Peptide aptamer mimicking RAD51-binding domain of BRCA2 inhibits DNA damage repair and survival in Trypanosoma brucei

Microbial Pathogenesis

Volumn 50, Issue 5, 2011, Pages 252-262

  Hall, Mack ^a   Misra, Smita ^a   Chaudhuri, Minu ^a   Chaudhuri, Gautam ^a  

^a MEHARRY MEDICAL COLLEGE   (United States)

Author keywords

Aptamer; BRCA2; DNA repair; Homologous recombination; Methyl methane sulfonate; RAD51; Trypanosoma brucei; Yeast 2 hybrid analysis

Indexed keywords

BRCA2 PROTEIN; MESYLIC ACID METHYL ESTER; PEPTIDE APTAMER; RAD51 PROTEIN;

AMINO ACID SEQUENCE; ANTIPROTOZOAL ACTIVITY; ARTICLE; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; HOMOLOGOUS RECOMBINATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE SURVIVAL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; TRYPANOSOMA BRUCEI; TWO HYBRID SYSTEM;

APTAMERS, PEPTIDE; BRCA2 PROTEIN; CELL SURVIVAL; DNA REPAIR; PROTEIN BINDING; PROTOZOAN PROTEINS; RAD51 RECOMBINASE; TRYPANOSOMA BRUCEI BRUCEI; TWO-HYBRID SYSTEM TECHNIQUES;

EUKARYOTA; MAMMALIA; PROTOZOA; TRYPANOSOMA BRUCEI;

EID: 79953045713     PISSN: 08824010     EISSN: 10961208     Source Type: Journal    
DOI: 10.1016/j.micpath.2010.11.007     Document Type: Article

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