메뉴 건너뛰기




Volumn 16, Issue 4, 2011, Pages 368-379

CNOT2 depletion disrupts and inhibits the CCR4-NOT deadenylase complex and induces apoptotic cell death

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CHEMOKINE RECEPTOR CCR4; CYCLOHEXIMIDE; PROTEIN CNOT2; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 79953016388     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2011.01492.x     Document Type: Article
Times cited : (66)

References (45)
  • 3
    • 0033911879 scopus 로고    scopus 로고
    • Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast
    • Badarinarayana, V., Chiang, Y.C. & Denis, C.L. (2000) Functional interaction of CCR4-NOT proteins with TATAA-binding protein (TBP) and its associated factors in yeast. Genetics 155, 1045-1054.
    • (2000) Genetics , vol.155 , pp. 1045-1054
    • Badarinarayana, V.1    Chiang, Y.C.2    Denis, C.L.3
  • 4
    • 33751188946 scopus 로고    scopus 로고
    • Cycloheximide protects HepG2 cells from serum withdrawal-induced apoptosis by decreasing p53 and phosphorylated p53 levels
    • Bai, J. & Cederbaum, A.I. (2006) Cycloheximide protects HepG2 cells from serum withdrawal-induced apoptosis by decreasing p53 and phosphorylated p53 levels. J. Pharmacol. Exp. Ther. 312, 1435-1443.
    • (2006) J. Pharmacol. Exp. Ther. , vol.312 , pp. 1435-1443
    • Bai, J.1    Cederbaum, A.I.2
  • 5
    • 0032874875 scopus 로고    scopus 로고
    • The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5
    • Bai, Y., Salvadore, C., Chiang, Y.C., Collart, M.A., Liu, H.Y. & Denis, C.L. (1999) The CCR4 and CAF1 proteins of the CCR4-NOT complex are physically and functionally separated from NOT2, NOT4, and NOT5. Mol. Cell. Biol. 19, 6642-6651.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 6642-6651
    • Bai, Y.1    Salvadore, C.2    Chiang, Y.C.3    Collart, M.A.4    Liu, H.Y.5    Denis, C.L.6
  • 6
    • 66049158810 scopus 로고    scopus 로고
    • Polysomes, P bodies and stress granules: states and fates of eukaryotic mRNAs
    • Balagopal, V. & Parker, R. (2009) Polysomes, P bodies and stress granules: states and fates of eukaryotic mRNAs. Curr. Opin. Cell Biol. 21, 403-408.
    • (2009) Curr. Opin. Cell Biol. , vol.21 , pp. 403-408
    • Balagopal, V.1    Parker, R.2
  • 7
    • 27144515901 scopus 로고    scopus 로고
    • Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies
    • Brengues, M., Teizeira, D. & Parker, R. (2005) Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies. Science 310, 486-489.
    • (2005) Science , vol.310 , pp. 486-489
    • Brengues, M.1    Teizeira, D.2    Parker, R.3
  • 8
    • 0030698129 scopus 로고    scopus 로고
    • A pathway distinct from the mammalian unfolded protein response regulates expression of endoplasmic reticulum chaperones in non-stressed cells
    • Brewer, J.W., Cleveland, J.L. & Hendershot, L.M. (1997) A pathway distinct from the mammalian unfolded protein response regulates expression of endoplasmic reticulum chaperones in non-stressed cells. EMBO J. 16, 7207-7216.
    • (1997) EMBO J. , vol.16 , pp. 7207-7216
    • Brewer, J.W.1    Cleveland, J.L.2    Hendershot, L.M.3
  • 9
    • 0037086701 scopus 로고    scopus 로고
    • CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase
    • Chen, J., Chiang, Y.C. & Denis, C.L. (2002) CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase. EMBO J. 21, 1414-1426.
    • (2002) EMBO J. , vol.21 , pp. 1414-1426
    • Chen, J.1    Chiang, Y.C.2    Denis, C.L.3
  • 10
    • 0242285769 scopus 로고    scopus 로고
    • Global control of gene expression in yeast by the Ccr4-Not complex
    • Collart, M.A. (2003) Global control of gene expression in yeast by the Ccr4-Not complex. Gene 313, 1-16.
    • (2003) Gene , vol.313 , pp. 1-16
    • Collart, M.A.1
  • 11
    • 0028268566 scopus 로고
    • NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization
    • Collart, M.A. & Struhl, K. (1994) NOT1(CDC39), NOT2(CDC36), NOT3, and NOT4 encode a global-negative regulator of transcription that differentially affects TATA-element utilization. Genes Dev. 8, 525-537.
    • (1994) Genes Dev. , vol.8 , pp. 525-537
    • Collart, M.A.1    Struhl, K.2
  • 12
    • 4143055666 scopus 로고    scopus 로고
    • The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways?
    • Collart, M.A. & Timmers, H.T. (2004) The eukaryotic Ccr4-not complex: a regulatory platform integrating mRNA metabolism with cellular signaling pathways? Prog. Nucleic Acid Res. Mol. Biol. 77, 289-322.
    • (2004) Prog. Nucleic Acid Res. Mol. Biol. , vol.77 , pp. 289-322
    • Collart, M.A.1    Timmers, H.T.2
  • 13
    • 2442566370 scopus 로고    scopus 로고
    • Cytoplasmic foci are sites of mRNA decay in human cells
    • Cougot, N., Babajko, S. & Seraphin, B. (2004) Cytoplasmic foci are sites of mRNA decay in human cells. J. Cell Biol. 165, 31-40.
    • (2004) J. Cell Biol. , vol.165 , pp. 31-40
    • Cougot, N.1    Babajko, S.2    Seraphin, B.3
  • 14
    • 0035875115 scopus 로고    scopus 로고
    • The yeast POP2 encodes a nuclease involved in mRNA deadenylation
    • Daugeron, M.C., Mauxion, F. & Seraphin, B. (2001) The yeast POP2 encodes a nuclease involved in mRNA deadenylation. Nucleic Acid Res. 29, 2448-2455.
    • (2001) Nucleic Acid Res. , vol.29 , pp. 2448-2455
    • Daugeron, M.C.1    Mauxion, F.2    Seraphin, B.3
  • 15
    • 0021702006 scopus 로고
    • Identification of new genes involved in the regulation of yeast alcohol dehydrogenase II
    • Denis, C.L. (1984) Identification of new genes involved in the regulation of yeast alcohol dehydrogenase II. Genetics 108, 833-844.
    • (1984) Genetics , vol.108 , pp. 833-844
    • Denis, C.L.1
  • 16
    • 0347323165 scopus 로고    scopus 로고
    • The CCR4-NOT complex plays diverse roles in mRNA metabolism
    • Denis, C.L. & Chen, J. (2003) The CCR4-NOT complex plays diverse roles in mRNA metabolism. Prog. Nucleic Acid Res. Mol. Biol. 73, 221-250.
    • (2003) Prog. Nucleic Acid Res. Mol. Biol. , vol.73 , pp. 221-250
    • Denis, C.L.1    Chen, J.2
  • 18
    • 0031882779 scopus 로고    scopus 로고
    • Regena (Rga), a Drosophila homolog of the global negative transcriptional regulator CDC36 (NOT2) from yeast, modifies gene expression and suppresses position effect variegation
    • Frolov, M.V., Benevolenskaya, E.V. & Birchler, J.A. (1998) Regena (Rga), a Drosophila homolog of the global negative transcriptional regulator CDC36 (NOT2) from yeast, modifies gene expression and suppresses position effect variegation. Genetics 148, 317-329.
    • (1998) Genetics , vol.148 , pp. 317-329
    • Frolov, M.V.1    Benevolenskaya, E.V.2    Birchler, J.A.3
  • 21
    • 0033231020 scopus 로고    scopus 로고
    • From receptors to stress-activated MAP kinases
    • Ichijo, H. (1999) From receptors to stress-activated MAP kinases. Oncogene 18, 6087-6093.
    • (1999) Oncogene , vol.18 , pp. 6087-6093
    • Ichijo, H.1
  • 22
    • 0036853914 scopus 로고    scopus 로고
    • Orchestrating the unfolded protein response in health and disease
    • Kaufman, R.J. (2002) Orchestrating the unfolded protein response in health and disease. J. Clin. Invest. 110, 1389-1398.
    • (2002) J. Clin. Invest. , vol.110 , pp. 1389-1398
    • Kaufman, R.J.1
  • 26
    • 0035831551 scopus 로고    scopus 로고
    • Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme
    • Liu, H.Y., Chiang, Y.C., Pan, J., Chen, J., Salvadore, C., Audino, D.C., Badarinarayana, V., Palaniswamy, V., Anderson, B. & Denis, C.L. (2001) Characterization of CAF4 and CAF16 reveals a functional connection between the CCR4-NOT complex and a subset of SRB proteins of the RNA polymerase II holoenzyme. J. Biol. Chem. 276, 7541-7548.
    • (2001) J. Biol. Chem. , vol.276 , pp. 7541-7548
    • Liu, H.Y.1    Chiang, Y.C.2    Pan, J.3    Chen, J.4    Salvadore, C.5    Audino, D.C.6    Badarinarayana, V.7    Palaniswamy, V.8    Anderson, B.9    Denis, C.L.10
  • 28
    • 0035144493 scopus 로고    scopus 로고
    • GADD153 sensitizes cells to endoplasmic reticulum stress by down- regulating BCL2 and perturbing the cellular redox state
    • McCullough, K.D., Martindale, J.L., Klotz, L.O., Aw, T.Y. & Holbrook, N.J. (2001) GADD153 sensitizes cells to endoplasmic reticulum stress by down- regulating BCL2 and perturbing the cellular redox state. Mol. Cell. Biol. 21, 1249-1259.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.O.3    Aw, T.Y.4    Holbrook, N.J.5
  • 30
    • 34347338699 scopus 로고    scopus 로고
    • Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth
    • Morita, M., Suzuki, T., Nakamura, T., Yokoyama, K., Miyasaka, T. & Yamamoto, T. (2007) Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth. Mol. Cell. Biol. 27, 4980-4990.
    • (2007) Mol. Cell. Biol. , vol.27 , pp. 4980-4990
    • Morita, M.1    Suzuki, T.2    Nakamura, T.3    Yokoyama, K.4    Miyasaka, T.5    Yamamoto, T.6
  • 31
    • 29244470510 scopus 로고    scopus 로고
    • Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells
    • Nawrocki, S.T., Carew, J.S., Dunner, K. Jr, Boise, L.H., Chiao, P.J., Huang, P., Abbruzzese, J.L. & McConkey, D.J. (2005) Bortezomib inhibits PKR-like endoplasmic reticulum (ER) kinase and induces apoptosis via ER stress in human pancreatic cancer cells. Cancer Res. 65, 11510-11519.
    • (2005) Cancer Res. , vol.65 , pp. 11510-11519
    • Nawrocki, S.T.1    Carew, J.S.2    Dunner Jr, K.3    Boise, L.H.4    Chiao, P.J.5    Huang, P.6    Abbruzzese, J.L.7    McConkey, D.J.8
  • 32
    • 0036971207 scopus 로고    scopus 로고
    • Characterization of mutations in NOT2 indicates that it plays an important role in maintaining the integrity of the CCR4-NOT complex
    • Russell, P., Benson, J.D. & Denis, C.L. (2002) Characterization of mutations in NOT2 indicates that it plays an important role in maintaining the integrity of the CCR4-NOT complex. J. Mol. Biol. 322, 27-39.
    • (2002) J. Mol. Biol. , vol.322 , pp. 27-39
    • Russell, P.1    Benson, J.D.2    Denis, C.L.3
  • 33
    • 0030817668 scopus 로고    scopus 로고
    • Cycloheximide prevents apoptosis, reactive oxygen species production, and glutathione depletion induced by transforming growth factor β in fetal rat hepatocytes in primary culture
    • Sanchez, A., Alvarez, A.M., Benito, M. & Fabregat, I. (1997) Cycloheximide prevents apoptosis, reactive oxygen species production, and glutathione depletion induced by transforming growth factor β in fetal rat hepatocytes in primary culture. Hepatology 26, 935-943.
    • (1997) Hepatology , vol.26 , pp. 935-943
    • Sanchez, A.1    Alvarez, A.M.2    Benito, M.3    Fabregat, I.4
  • 34
    • 41449116766 scopus 로고    scopus 로고
    • Ero1 and redox homeostasis in the endoplasmic reticulum
    • Sevier, C.S. & Kaiser, C.A. (2008) Ero1 and redox homeostasis in the endoplasmic reticulum. Biochem. Biophys. Acta 2783, 549-556.
    • (2008) Biochem. Biophys. Acta , vol.2783 , pp. 549-556
    • Sevier, C.S.1    Kaiser, C.A.2
  • 35
    • 0037968357 scopus 로고    scopus 로고
    • Decapping and decay of messenger RNA occur in cytoplasmic processing bodies
    • Sheth, U. & Parker, R. (2003) Decapping and decay of messenger RNA occur in cytoplasmic processing bodies. Science 300, 805-808.
    • (2003) Science , vol.300 , pp. 805-808
    • Sheth, U.1    Parker, R.2
  • 36
    • 15844431376 scopus 로고    scopus 로고
    • Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans
    • Sonnichsen, B., Koski, L.B., Walsh, A., Marschall, P. & Neumann, B. (2005) Full-genome RNAi profiling of early embryogenesis in Caenorhabditis elegans. Nature 434, 462-469.
    • (2005) Nature , vol.434 , pp. 462-469
    • Sonnichsen, B.1    Koski, L.B.2    Walsh, A.3    Marschall, P.4    Neumann, B.5
  • 37
    • 77649252314 scopus 로고    scopus 로고
    • NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs
    • Suzuki, A., Igarashi, K., Aisaki, K., Kanno, J. & Saga, Y. (2010) NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc. Natl Acad. Sci. USA 23, 3594-3599.
    • (2010) Proc. Natl Acad. Sci. USA , vol.23 , pp. 3594-3599
    • Suzuki, A.1    Igarashi, K.2    Aisaki, K.3    Kanno, J.4    Saga, Y.5
  • 38
    • 34250374824 scopus 로고    scopus 로고
    • Analysis of P-body assembly in Saccharomyces cerevisiae
    • Teixeira, D. & Parker, R. (2007) Analysis of P-body assembly in Saccharomyces cerevisiae. Mol. Biol. Cell 18, 2274-2287.
    • (2007) Mol. Biol. Cell , vol.18 , pp. 2274-2287
    • Teixeira, D.1    Parker, R.2
  • 39
    • 3543016170 scopus 로고    scopus 로고
    • A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila
    • Temme, C., Zaessinger, S., Meyer, S., Simonelig, M. & Wahle, E. (2004) A complex containing the CCR4 and CAF1 proteins is involved in mRNA deadenylation in Drosophila. EMBO J. 23, 2862-2871.
    • (2004) EMBO J. , vol.23 , pp. 2862-2871
    • Temme, C.1    Zaessinger, S.2    Meyer, S.3    Simonelig, M.4    Wahle, E.5
  • 40
    • 0035830508 scopus 로고    scopus 로고
    • The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae
    • Tucker, M., Valencia-Sanchez, M.A., Staples, R.R., Chen, J., Denis, C.L. & Parker, R. (2001) The transcription factor associated Ccr4 and Caf1 proteins are components of the major cytoplasmic mRNA deadenylase in Saccharomyces cerevisiae. Cell 104, 377-386.
    • (2001) Cell , vol.104 , pp. 377-386
    • Tucker, M.1    Valencia-Sanchez, M.A.2    Staples, R.R.3    Chen, J.4    Denis, C.L.5    Parker, R.6
  • 42
    • 33746295893 scopus 로고    scopus 로고
    • Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription
    • Winkler, G.S., Mulder, K.W., Bardwell, V.J., Kalkhoven, E. & Timmers, H.T. (2006) Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription. EMBO J. 25, 3089-3099.
    • (2006) EMBO J. , vol.25 , pp. 3089-3099
    • Winkler, G.S.1    Mulder, K.W.2    Bardwell, V.J.3    Kalkhoven, E.4    Timmers, H.T.5
  • 43
    • 47549087539 scopus 로고    scopus 로고
    • Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells
    • Zheng, D., Ezzeddine, N., Chen, C.Y., Zhu, W., He, X. & Shyu, A.B. (2008) Deadenylation is prerequisite for P-body formation and mRNA decay in mammalian cells. J. Cell Biol. 182, 89-101.
    • (2008) J. Cell Biol. , vol.182 , pp. 89-101
    • Zheng, D.1    Ezzeddine, N.2    Chen, C.Y.3    Zhu, W.4    He, X.5    Shyu, A.B.6
  • 44
    • 0032054744 scopus 로고    scopus 로고
    • CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum
    • Zinszner, H., Kuroda, M., Wang, X., Bathchvarova, N., Lightfoot, T., Remotti, H., Stevens, J.L. & Ron, D. (1998) CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum. Genes Dev. 12, 982-995.
    • (1998) Genes Dev. , vol.12 , pp. 982-995
    • Zinszner, H.1    Kuroda, M.2    Wang, X.3    Bathchvarova, N.4    Lightfoot, T.5    Remotti, H.6    Stevens, J.L.7    Ron, D.8
  • 45
    • 1642483755 scopus 로고    scopus 로고
    • Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex
    • Zwartjes, C.G., Jayne, S., van den Berg, D.L. & Timmers, H.T. (2004) Repression of promoter activity by CNOT2, a subunit of the transcription regulatory Ccr4-not complex. J. Biol. Chem. 279, 10848-10854.
    • (2004) J. Biol. Chem. , vol.279 , pp. 10848-10854
    • Zwartjes, C.G.1    Jayne, S.2    van den Berg, D.L.3    Timmers, H.T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.