-
1
-
-
0036780907
-
Evolutionary and historical aspects of the burden of malaria
-
DOI 10.1128/CMR.15.4.564-594.2002
-
Carter R, Mendis KN. Evolutionary and historical aspects of the burden of malaria. Clin Microbiol Rev 2002;15:564-94 (Pubitemid 41184079)
-
(2002)
Clinical Microbiology Reviews
, vol.15
, Issue.4
, pp. 564-594
-
-
Carter, R.1
Mendis, K.N.2
-
2
-
-
79952968165
-
-
2008
-
WHO. Malaria report, 2008. Available from: http://wwwwhoint/malaria/ publications/atoz/9789241563697/en/indexhtml 2008
-
(2008)
(WHO) WHO Malaria Report
-
-
-
3
-
-
40049110830
-
Artemisinin-based combination treatment of falciparum malaria
-
Nosten F, White NJ. Artemisinin-based combination treatment of falciparum malaria. Am J Trop Med Hyg 2007;77:181-92
-
(2007)
Am J Trop Med Hyg
, vol.77
, pp. 181-92
-
-
Nosten, F.1
White, N.J.2
-
4
-
-
0031722604
-
Safety assessment of peroxide antimalarials: Clinical and chemical perspectives
-
DOI 10.1046/j.1365-2125.1998.00838.x
-
Park BK, O?Neill PM, Maggs JL, et al. Safety assessment of peroxide antimalarials: clinical and chemical perspectives. Br J Clin Pharmacol 1998;46:521-9 (Pubitemid 28522114)
-
(1998)
British Journal of Clinical Pharmacology
, vol.46
, Issue.6
, pp. 521-529
-
-
Kevin Park, B.1
O'Neill, P.M.2
Maggs, J.L.3
Pirmohamed, M.4
-
6
-
-
73849135944
-
Pharmacokinetics of artemether-lumefantrine and artesunate-amodiaquine in children in Kampala, Uganda
-
Mwesigwa J, Parikh S, McGee B, et al. Pharmacokinetics of artemether-lumefantrine and artesunate-amodiaquine in children in Kampala, Uganda. Antimicrob Agents Chemother 2010;54:52-9
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 52-9
-
-
Mwesigwa, J.1
Parikh, S.2
McGee, B.3
-
7
-
-
70349085389
-
Population pharmacokinetics of artesunate and amodiaquine in African children
-
Stepniewska K, Taylor W, Sirima SB, et al. Population pharmacokinetics of artesunate and amodiaquine in African children. Malar J 2009;8:200
-
(2009)
Malar J
, vol.8
, pp. 200
-
-
Stepniewska, K.1
Taylor, W.2
Sirima, S.B.3
-
8
-
-
56549110631
-
Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: A randomised, single-blind, multicentre trial
-
Abdulla S, Sagara I, Borrmann S, et al. Efficacy and safety of artemether-lumefantrine dispersible tablets compared with crushed commercial tablets in African infants and children with uncomplicated malaria: a randomised, single-blind, multicentre trial. Lancet 2008;372:1819-27
-
(2008)
Lancet
, vol.372
, pp. 1819-27
-
-
Abdulla, S.1
Sagara, I.2
Borrmann, S.3
-
9
-
-
74849111616
-
Do paediatric drug formulations of artemisinin combination therapies improve the treatment of children with malaria? A systematic review and meta-analysis
-
Kurth F, Belard S, Adegnika AA, et al. Do paediatric drug formulations of artemisinin combination therapies improve the treatment of children with malaria? A systematic review and meta-analysis. Lancet Infect Dis 2010;10:125-32
-
(2010)
Lancet Infect Dis
, vol.10
, pp. 125-32
-
-
Kurth, F.1
Belard, S.2
Adegnika, A.A.3
-
10
-
-
74049133225
-
A randomized trial of artesunate mefloquine versus artemether lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Senegalese children
-
Faye B, Ndiaye JL, Tine R, et al. A randomized trial of artesunate mefloquine versus artemether lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Senegalese children. Am J Trop Med Hyg 2010;82:140-4
-
(2010)
Am J Trop Med Hyg
, vol.82
, pp. 140-4
-
-
Faye, B.1
Ndiaye, J.L.2
Tine, R.3
-
11
-
-
77952476472
-
Efficacy and safety of a new pediatric artesunate-mefloquine drug formulation for the treatment of uncomplicated falciparum malaria in Gabon
-
Bouyou-Akotet MK, Ramharter M, Ngoungou EB, et al. Efficacy and safety of a new pediatric artesunate-mefloquine drug formulation for the treatment of uncomplicated falciparum malaria in Gabon. Wien Klin Wochenschr 2010;122:173-8
-
(2010)
Wien Klin Wochenschr
, vol.122
, pp. 173-8
-
-
Bouyou-Akotet, M.K.1
Ramharter, M.2
Ngoungou, E.B.3
-
12
-
-
2542640961
-
A medicinal chemistry perspective on artemisinin and related endoperoxides
-
DOI 10.1021/jm030571c
-
O?Neill PM, Posner GH. A medicinal chemistry perspective on artemisinin and related endoperoxides. J Med Chem 2004;47:2945-64 (Pubitemid 38702690)
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, Issue.12
, pp. 2945-2964
-
-
O'Neill, P.M.1
Posner, G.H.2
-
13
-
-
0027197112
-
Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu)
-
Meshnick SR, Yang YZ, Lima V, et al. Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu). Antimicrob Agents Chemother 1993;37:1108-14 (Pubitemid 23141328)
-
(1993)
Antimicrobial Agents and Chemotherapy
, vol.37
, Issue.5
, pp. 1108-1114
-
-
Meshnick, S.R.1
Yang, Y.-Z.2
Lima, V.3
Kuypers, F.4
Kamchonwongpaisan, S.5
Yuthavong, Y.6
-
14
-
-
34548293148
-
Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs
-
DOI 10.1002/anie.200604697
-
Stocks PA, Bray PG, Barton VE, et al. Evidence for a common non-heme chelatable-iron-dependent activation mechanism for semisynthetic and synthetic endoperoxide antimalarial drugs. Angew ChemInt Ed 2007;46:6278-83 (Pubitemid 47329416)
-
(2007)
Angewandte Chemie - International Edition
, vol.46
, Issue.33
, pp. 6278-6283
-
-
Stocks, P.A.1
Bray, P.G.2
Barton, V.E.3
Al-Helal, M.4
Jones, M.5
Araujo, N.C.6
Gibbons, P.7
Ward, S.A.8
Hughes, R.H.9
Biagini, G.A.10
Davies, J.11
Amewu, R.12
Mercer, A.E.13
Ellis, G.14
O'Neill, P.M.15
-
15
-
-
0042860063
-
Artemisinins target the SERCA of Plasmodium falciparum
-
DOI 10.1038/nature01813
-
Eckstein-Ludwig U, Webb RJ, van Goethem IDA, et al. Artemisinins target the SERCA of plasmodium falciparum. Nature 2003;424:957-61 (Pubitemid 37051688)
-
(2003)
Nature
, vol.424
, Issue.6951
, pp. 957-961
-
-
Eckstein-Ludwig, U.1
Webb, R.J.2
Van Goethem, I.D.A.3
East, J.M.4
Lee, A.G.5
Kimura, M.6
O'Neill, P.M.7
Bray, P.G.8
Ward, S.A.9
Krishna, S.10
-
16
-
-
0030893778
-
Artemisinin enhances heme-catalysed oxidation of lipid membranes
-
DOI 10.1016/S0891-5849(96)00508-4, PII S0891584996005084
-
Berman PA, Adams PA. Artemisinin enhances heme-catalysed oxidation of lipid membranes. Free Radic Biol Med 1997;22:1283-8 (Pubitemid 27171971)
-
(1997)
Free Radical Biology and Medicine
, vol.22
, Issue.7
, pp. 1283-1288
-
-
Berman, P.A.1
Adams, P.A.2
-
17
-
-
26444465676
-
The antimalarial drug artemisinin alkylates heme in infected mice
-
DOI 10.1073/pnas.0500972102
-
Robert A, Benoit-Vical F, Claparols C, et al. The antimalarial drug artemisinin alkylates heme in infected mice. Proc Natl Acad Sci USA 2005;102:13676-80 (Pubitemid 41420907)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.38
, pp. 13676-13680
-
-
Robert, A.1
Benoit-Vical, F.2
Claparols, C.3
Meunier, B.4
-
18
-
-
0141483123
-
450s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data
-
DOI 10.1007/s00228-003-0636-9
-
Li XQ, Bjorkman A, Andersson TB, et al. Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data. Eur J Clin Pharmacol 2003;59:429-42 (Pubitemid 37214951)
-
(2003)
European Journal of Clinical Pharmacology
, vol.59
, Issue.5-6
, pp. 429-442
-
-
Li, X.-Q.1
Bjorkman, A.2
Andersson, T.B.3
Gustafsson, L.L.4
Masimirembwa, C.M.5
-
19
-
-
0033959522
-
Biliary metabolites of β-artemether in rats: Biotransformations of an antimalarial endoperoxide
-
Maggs JL, Bishop LPD, Edwards G, et al. Biliary metabolites of beta-artemether in rats: Biotransformations of an antimalarial endoperoxide. Drug Metab Dispos 2000;28:209-17 (Pubitemid 30069006)
-
(2000)
Drug Metabolism and Disposition
, vol.28
, Issue.2
, pp. 209-217
-
-
Maggs, J.L.1
Bishop, L.P.D.2
Edwards, G.3
O'Neill, P.M.4
Ward, S.A.5
Winstanley, P.A.6
Park, B.K.7
-
20
-
-
0030879988
-
The rat biliary metabolites of dihydroartemisinin, an antimalarial endoperoxide
-
Maggs JL, Madden S, Bishop LP, et al. The rat biliary metabolites of dihydroartemisinin, an antimalarial endoperoxide. Drug Metab Dispos 1997;25:1200-4 (Pubitemid 27446591)
-
(1997)
Drug Metabolism and Disposition
, vol.25
, Issue.10
, pp. 1200-1204
-
-
Maggs, J.L.1
Madden, S.2
Bishop, L.P.3
O'Neill, P.M.4
Park, B.K.5
-
21
-
-
33645120407
-
Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer
-
Nagar S, Remmel RP. Uridine diphosphoglucuronosyltransferase pharmacogenetics and cancer. Oncogene 2006;25:1659-72
-
(2006)
Oncogene
, vol.25
, pp. 1659-72
-
-
Nagar, S.1
Remmel, R.P.2
-
22
-
-
71849088050
-
Pharmacogenetics of antimalarial drugs: Effect on metabolism and transport
-
Kerb R, Fux R, Morike K, et al. Pharmacogenetics of antimalarial drugs: effect on metabolism and transport. Lancet Infect Dis 2009;9:760-74
-
(2009)
Lancet Infect Dis
, vol.9
, pp. 760-74
-
-
Kerb, R.1
Fux, R.2
Morike, K.3
-
24
-
-
70350146352
-
Pharmacokinetic and toxicological profile of artemisinin compounds: An update
-
Medhi B, Patyar S, Rao RS, et al. Pharmacokinetic and toxicological profile of artemisinin compounds: an update. Pharmacology 2009;84:323-32
-
(2009)
Pharmacology
, vol.84
, pp. 323-32
-
-
Medhi, B.1
Patyar, S.2
Rao, R.S.3
-
25
-
-
70349963483
-
Embryotoxicity of the artemisinin antimalarials and potential consequences for use in women in the first trimester
-
Clark RL. Embryotoxicity of the artemisinin antimalarials and potential consequences for use in women in the first trimester. Reprod Toxicol 2009;28:285-96
-
(2009)
Reprod Toxicol
, vol.28
, pp. 285-96
-
-
Clark, R.L.1
-
26
-
-
34248229771
-
Evidence for the involvement of carbon-centered radicals in the induction of apoptotic cell death by artemisinin compounds
-
DOI 10.1074/jbc.M610375200
-
Mercer AE, Maggs JL, Sun XM, et al. Evidence for the involvement of carbon-centered radicals in the induction of apoptotic cell death by artemisinin compounds. J Biol Chem 2007;282:9372-82 (Pubitemid 47104599)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.13
, pp. 9372-9382
-
-
Mercer, A.E.1
Maggs, J.L.2
Sun, X.-M.3
Cohen, G.M.4
Chadwick, J.5
O'Neill, P.M.6
Park, B.K.7
-
27
-
-
58449099020
-
The role of bioactivation in the pharmacology and toxicology of the artemisinin-based antimalarials
-
Mercer AE. The role of bioactivation in the pharmacology and toxicology of the artemisinin-based antimalarials. Curr Opin Drug Discov Dev 2009;12:125-32
-
(2009)
Curr Opin Drug Discov Dev
, vol.12
, pp. 125-32
-
-
Mercer, A.E.1
-
28
-
-
28244475056
-
Dihydroartemisinin is cytotoxic to papillomavirus-expressing epithelial cells in vitro and in vivo
-
DOI 10.1158/0008-5472.CAN-05-1216
-
Disbrow GL, Baege AC, Kierpiec KA, et al. Dihydroartemisinin is cytotoxic to papillomavirus-expressing epithelial cells in vitro and in vivo. Cancer Res 2005;65:10854-61 (Pubitemid 41713353)
-
(2005)
Cancer Research
, vol.65
, Issue.23
, pp. 10854-10861
-
-
Disbrow, G.L.1
Baege, A.C.2
Kierpiec, K.A.3
Yuan, H.4
Centeno, J.A.5
Thibodeaux, C.A.6
Hartmann, D.7
Schlegel, R.8
-
29
-
-
70449562761
-
Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target
-
Zhang S, Gerhard GS. Heme mediates cytotoxicity from artemisinin and serves as a general anti-proliferation target. Plos One 2009;4:e7472
-
(2009)
Plos One
, vol.4
-
-
Zhang, S.1
Gerhard, G.S.2
-
30
-
-
11344274401
-
Pharmacokinetic investigation on the therapeutic potential of Artemotil (β-arteether) in Thai patients with severe Plasmodium falciparum malaria
-
Li QG, Lugt CB, Looareesuwan S, et al. Pharmacokinetic investigation on the therapeutic potential of artemotil (beta-arteether) in Thai patients with severe plasmodium falciparum malaria. Am J Trop Med Hyg 2004;71:723-31 (Pubitemid 40075620)
-
(2004)
American Journal of Tropical Medicine and Hygiene
, vol.71
, Issue.6
, pp. 723-731
-
-
Li, Q.1
Lugt, C.B.2
Looareesuwan, S.3
Krudsood, S.4
Wilairatana, P.5
Vannaphan, S.6
Chalearmrult, K.7
Milhous, W.K.8
-
31
-
-
0035999639
-
Dose-finding and efficacy study for i.m. artemotil (beta-arteether) and comparison with i.m. artemether in acute uncomplicated P. falciparum malaria
-
DOI 10.1046/j.1365-2125.2002.01590.x
-
Looareesuwan S, Oosterhuis B, Schilizzi BM, et al. Dose-finding and efficacy study for i.m. artemotil (beta-arteether) and comparison with i.m. artemether in acute uncomplicated P-falciparum malaria. Br J Clin Pharmacol 2002;53:492-500 (Pubitemid 34526501)
-
(2002)
British Journal of Clinical Pharmacology
, vol.53
, Issue.5
, pp. 492-500
-
-
Looareesuwan, S.1
Oosterhuis, B.2
Schilizzi, B.M.3
Sollie, F.A.E.4
Wilairatana, P.5
Krudsood, S.6
Lugt, Ch.B.7
Peeters, P.A.M.8
Peggins, J.O.9
-
32
-
-
45349106663
-
Impaired clinical response in a patient with uncomplicated falciparum malaria who received poor-quality and underdosed intramuscular artemether
-
Keoluangkhot V, Green MD, Nyadong L, et al. Impaired clinical response in a patient with uncomplicated falciparum malaria who received poor-quality and underdosed intramuscular artemether. Am J Trop Med Hyg 2008;78:552-5 (Pubitemid 351845155)
-
(2008)
American Journal of Tropical Medicine and Hygiene
, vol.78
, Issue.4
, pp. 552-555
-
-
Keoluangkhot, V.1
Green, M.D.2
Nyadong, L.3
Fernandez, F.M.4
Mayxay, M.5
Newton, P.N.6
-
33
-
-
0032804039
-
The pfmdr1 gene is associated with a multidrug-resistant phenotype in plasmodium falciparum from the western border of Thailand
-
Price RN, Cassar C, Brockman A, et al. The pfmdr1 gene is associated with a multidrug-resistant phenotype in plasmodium falciparum from the western border of Thailand. Antimicrob Agents Chemother 1999;43:2943-9
-
(1999)
Antimicrob Agents Chemother
, vol.43
, pp. 2943-9
-
-
Price, R.N.1
Cassar, C.2
Brockman, A.3
-
34
-
-
0036168512
-
Oral artesunate dose-response relationship in acute falciparum malaria
-
DOI 10.1128/AAC.46.3.778-782.2002
-
Angus BJ, Thaiaporn I, Chanthapadith K, et al. Oral artesunate dose-response relationship in acute falciparum malaria. Antimicrob Agents Chemother 2002;46:778-82 (Pubitemid 34157663)
-
(2002)
Antimicrobial Agents and Chemotherapy
, vol.46
, Issue.3
, pp. 778-782
-
-
Angus, B.J.1
Thaiaporn, I.2
Chanthapadith, K.3
Suputtamongkol, Y.4
White, N.J.5
-
35
-
-
1642482269
-
Artemisinin derivatives: Toxic for laboratory animals, safe for humans?
-
DOI 10.1016/j.toxlet.2003.12.009
-
Gordi T, Lepist EI. Artemisinin derivatives: toxic for laboratory animals, safe for humans? Toxicol Lett 2004;147:99-107 (Pubitemid 38130178)
-
(2004)
Toxicology Letters
, vol.147
, Issue.2
, pp. 99-107
-
-
Gordi, T.1
Lepist, E.-I.2
-
36
-
-
12244298238
-
Penetration of dihydroartemisinin into cerebrospinal fluid after administration of intravenous artesunate in severe falciparum malaria
-
DOI 10.1128/AAC.47.1.368-370.2003
-
Davis TME, Binh TQ, Ilett KF, et al. Penetration of dihydroartemisinin into cerebrospinal fluid after administration of intravenous artesunate in severe falciparum malaria. Antimicrob Agents Chemother 2003;47:368-70 (Pubitemid 36070387)
-
(2003)
Antimicrobial Agents and Chemotherapy
, vol.47
, Issue.1
, pp. 368-370
-
-
Davis, T.M.E.1
Binh, T.Q.2
Ilett, K.F.3
Batty, K.T.4
Phuong, H.L.5
Chiswell, G.M.6
Phuong, V.D.B.7
Agus, C.8
-
37
-
-
0031963524
-
A pharmacokinetic and pharmacodynamic study of intravenous vs oral artesunate in uncomplicated falciparum malaria
-
DOI 10.1046/j.1365-2125.1998.00655.x
-
Batty KT, Thu LTA, Davis TME, et al. A pharmacokinetic and pharmacodynamic study of intravenous vs oral artesunate in uncomplicated falciparum malaria. Br J Clin Pharmacol 1998;45:123-9 (Pubitemid 28045678)
-
(1998)
British Journal of Clinical Pharmacology
, vol.45
, Issue.2
, pp. 123-129
-
-
Batty, K.T.1
Thu, L.T.A.2
Davis, T.M.E.3
Ilett, K.F.4
Mai, T.X.5
Hung, N.C.6
Tien, N.P.7
Powell, S.M.8
Thien, H.V.9
Binh, T.Q.10
Kim, N.V.11
-
38
-
-
0031758826
-
A pharmacokinetic and pharmacodynamic study of artesunate for vivax malaria
-
Batty KT, Thu LA, Ilett KF, et al. A pharmacokinetic and pharmacodynamic study of artesunate for vivax malaria. Am J Trop Med Hyg 1998;59:823-7 (Pubitemid 28524545)
-
(1998)
American Journal of Tropical Medicine and Hygiene
, vol.59
, Issue.5
, pp. 823-827
-
-
Batty, K.T.1
Thu, L.T.A.2
Ilett, K.F.3
Tien, N.P.4
Powell, S.M.5
Hung, N.C.6
Mai, T.X.7
Van Chon, V.8
Van Thien, H.9
Binh, T.Q.10
Van Kim, N.11
Davis, T.M.E.12
-
39
-
-
3342899925
-
Disposition of artesunate and dihydroartemisinin after administration of artesunate suppositories in children from Papua New Guinea with uncomplicated malaria
-
DOI 10.1128/AAC.48.8.2966-2972.2004
-
Karunajeewa HA, Ilett KF, Dufall K, et al. Disposition of artesunate and dihydroartemisinin after administration of artesunate suppositories in children from Papua New Guinea with uncomplicated malaria. Antimicrob Agents Chemother 2004;48:2966-72 (Pubitemid 38989162)
-
(2004)
Antimicrobial Agents and Chemotherapy
, vol.48
, Issue.8
, pp. 2966-2972
-
-
Karunajeewa, H.A.1
Ilett, K.F.2
Dufall, K.3
Kemiki, A.4
Bockarie, M.5
Alpers, M.P.6
Barrett, P.H.7
Vicini, P.8
Davis, T.M.E.9
-
40
-
-
0031900724
-
Plasma levels of artesunate and dihydroartemisinin in children with Plasmodium falciparum malaria in Gabon after administration of 50-milligram artesunate suppositories
-
Halpaap B, Ndjave M, Paris M, et al. Plasma levels of artesunate and dihydroartemisinin in children with plasmodium falciparum malaria in Gabon after administration of 50-milligram artesunate suppositories. Am J Trop Med Hyg 1998;58:365-8 (Pubitemid 28160762)
-
(1998)
American Journal of Tropical Medicine and Hygiene
, vol.58
, Issue.3
, pp. 365-368
-
-
Halpaap, B.1
Ndjave, M.2
Paris, M.3
Benakis, A.4
Kremsner, P.G.5
-
41
-
-
34447332876
-
Comparative study of the effectiveness and pharmacokinetics of two rectal artesunate/oral mefloquine combination regimens for the treatment of uncomplicated childhood falciparum malaria
-
DOI 10.1179/146532807X170466
-
Sirivichayakul C, Sabchareon A, Pengsaa K, et al. Comparative study of the effectiveness and pharmacokinetics of two rectal artesunate oral mefloquine combination regimens for the treatment of uncomplicated childhood falciparum malaria. Ann Trop Paediatr 2007;27:17-24 (Pubitemid 47628957)
-
(2007)
Annals of Tropical Paediatrics
, vol.27
, Issue.1
, pp. 17-24
-
-
Sirivichayakul, C.1
Sabchareon, A.2
Pengsaa, K.3
Thaiarporn, I.4
Chaivisuth, A.5
Na-Bangchang, K.6
Wisetsing, P.7
Chanthavanich, P.8
Pojjaroen-Anant, C.9
-
42
-
-
0031917554
-
Comparative clinical trial of artesunate suppositories and oral artesunate in combination with mefloquine in the treatment of children with acute falciparum malaria
-
Sabchareon A, Attanath P, Chanthavanich P, et al. Comparative clinical trial of artesunate suppositories and oral artesunate in combination with mefloquine ln the treatment of children with acute falciparum malaria. Am J Trop Med Hyg 1998;58:11-16 (Pubitemid 28071402)
-
(1998)
American Journal of Tropical Medicine and Hygiene
, vol.58
, Issue.1
, pp. 11-16
-
-
Sabchareon, A.1
Attanath, P.2
Chanthavanich, P.3
Phanuaksook, P.4
Prarinyanupharb, V.5
Poonpanich, Y.6
Mookmanee, D.7
Teja-Isavadharm, P.8
Heppner, D.G.9
Brewer, T.G.10
Chongsuphajaisiddhi, T.11
-
43
-
-
0035143173
-
Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria
-
DOI 10.1128/AAC.45.2.509-516.2001
-
Krishna S, Planche T, Agbenyega T, et al. Bioavailability and preliminary clinical efficacy of intrarectal artesunate in Ghanaian children with moderate malaria. Antimicrob Agents Chemother 2001;45:509-16 (Pubitemid 32105288)
-
(2001)
Antimicrobial Agents and Chemotherapy
, vol.45
, Issue.2
, pp. 509-516
-
-
Krishna, S.1
Planche, T.2
Agbenyega, T.3
Woodrow, C.4
Agranoff, D.5
Bedu-Addo, G.6
Owusu-Ofori, A.K.7
Appiah, J.A.8
Ramanathan, S.9
Mansor, S.M.10
Navaratnam, V.11
-
45
-
-
12644290292
-
Pharmacokinetics of oral artesunate in children with moderately severe Plasmodium falciparum malaria
-
Bethell DB, TejaIsavadharm P, Cao XTP, et al. Pharmacokinetics of oral artesunate in children with moderately severe plasmodium falciparum malaria. Trans R Soc Trop Med Hyg 1997;91:195-8 (Pubitemid 27197293)
-
(1997)
Transactions of the Royal Society of Tropical Medicine and Hygiene
, vol.91
, Issue.2
, pp. 195-198
-
-
Bethell, D.B.1
Teja-Isavadharm, P.2
Phuong, C.X.T.3
Thuy, P.T.T.4
Mai, T.T.T.5
Thuy, T.T.N.6
Ha, N.T.T.7
Phuong, P.T.8
Kyle, D.9
Day, N.P.J.10
White, N.J.11
-
46
-
-
35448966698
-
Pharmacokinetics of two paediatric artesunate-mefloquine drug formulations in the treatment of uncomplicated falciparum malaria in Gabon
-
DOI 10.1093/jac/dkm355
-
Ramharter M, Kurth FM, Belard S, et al. Pharmacokinetics of two paediatric artesunate-mefloquine drug formulations in the treatment of uncomplicated falciparum malaria in Gabon. J Antimicrob Chemother 2007;60:1091-6 (Pubitemid 47617759)
-
(2007)
Journal of Antimicrobial Chemotherapy
, vol.60
, Issue.5
, pp. 1091-1096
-
-
Ramharter, M.1
Kurth, F.M.2
Belard, S.3
Bouyou-Akotet, M.K.4
Mamfoumbi, M.M.5
Agnandji, S.T.6
Missinou, M.A.7
Adegnika, A.A.8
Issifou, S.9
Cambon, N.10
Heidecker, J.L.11
Kombila, M.12
Kremsner, P.G.13
-
47
-
-
0031886621
-
Artemisinin population pharmacokinetics in children and adults with uncomplicated falciparum malaria
-
DOI 10.1046/j.1365-2125.1998.00686.x
-
Sidhu JS, Ashton M, Huong NV, et al. Artemisinin population pharmacokinetics in children and adults with uncomplicated falciparum malaria. Br J Clin Pharmacol 1998;45:347-54 (Pubitemid 28138826)
-
(1998)
British Journal of Clinical Pharmacology
, vol.45
, Issue.4
, pp. 347-354
-
-
Sidhu, J.S.1
Ashton, M.2
Huong, N.V.3
Hai, T.N.4
Karlsson, M.O.5
Sy, N.D.6
Jonsson, E.N.7
Cong, L.D.8
-
48
-
-
51749098784
-
Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon
-
Ramharter M, Kurth F, Schreier AC, et al. Fixed-dose pyronaridine- artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon. J Infect Dis 2008;198:911-19
-
(2008)
J Infect Dis
, vol.198
, pp. 911-19
-
-
Ramharter, M.1
Kurth, F.2
Schreier, A.C.3
-
49
-
-
33845294744
-
Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients
-
Simpson JA, Agbenyega T, Barnes KI, et al. Population pharmacokinetics of artesunate and dihydroartemisinin following intra-rectal dosing of artesunate in malaria patients. PLoS Med 2006;3:e444
-
(2006)
PLoS Med
, vol.3
-
-
Simpson, J.A.1
Agbenyega, T.2
Barnes, K.I.3
-
50
-
-
70350100287
-
Artemisinin resistance on the Thai-Cambodian border
-
Yeung S, Socheat D, Moorthy VS, et al. Artemisinin resistance on the Thai-Cambodian border. Lancet 2009;374:1418-19
-
(2009)
Lancet
, vol.374
, pp. 1418-19
-
-
Yeung, S.1
Socheat, D.2
Moorthy, V.S.3
-
52
-
-
34447512467
-
Prediction of drug clearance in children: Impact of allometric exponents, body weight, and age
-
DOI 10.1097/FTD.0b013e318042d3c4, PII 0000769120070600000002
-
Mahmood I. Prediction of drug clearance in children: impact of allometric exponents, body weight, and age. Ther Drug Monit 2007;29:271-8 (Pubitemid 47262255)
-
(2007)
Therapeutic Drug Monitoring
, vol.29
, Issue.3
, pp. 271-278
-
-
Mahmood, I.1
-
53
-
-
0141857724
-
Developmental pharmacology - Drug disposition, action, and therapy in infants and children
-
DOI 10.1056/NEJMra035092
-
Kearns GL, Abdel-Rahman SM, Alander SW, et al. Developmental pharmacology -drug disposition, action, and therapy in infants and children. N Engl J Med 2003;349:1157-67 (Pubitemid 37122329)
-
(2003)
New England Journal of Medicine
, vol.349
, Issue.12
, pp. 1157-1167
-
-
Kearns, G.L.1
Abdel-Rahman, S.M.2
Alander, S.W.3
Blowey, D.L.4
Leeder, J.S.5
Kauffman, R.E.6
-
54
-
-
33646932658
-
Back to basics: Understanding drugs in children: Pharmacokinetic maturation
-
Tetelbaum M, Finkelstein Y, Nava-Ocampo AA, et al. Back to basics: understanding drugs in children: pharmacokinetic maturation. Pediatr Rev 2005;26:321-8
-
(2005)
Pediatr Rev
, vol.26
, pp. 321-8
-
-
Tetelbaum, M.1
Finkelstein, Y.2
Nava-Ocampo, A.A.3
-
55
-
-
0032806472
-
Malaria parasitemia and childhood diarrhea in a peri-urban area of Guinea-Bissau
-
Sodemann M, Jakobsen M, Molbak K, et al. Malaria parasitemia and childhood diarrhea in a peri-urban area of Guinea-Bissau. Am J Trop Med Hyg 1999;61:336-8 (Pubitemid 29380272)
-
(1999)
American Journal of Tropical Medicine and Hygiene
, vol.61
, Issue.2
, pp. 336-338
-
-
Sodemann, M.1
Jakobsen, M.S.2
Molbak, K.3
Alvarenga, I.C.4
Martins, C.5
Aaby, P.6
-
56
-
-
0141791117
-
The development of drug metabolising enzymes and their influence on the susceptibility to adverse drug reactions in children
-
DOI 10.1016/S0300-483X(03)00249-X
-
Johnson TN. The development of drug metabolising enzymes and their influence on the susceptibility to adverse drug reactions in children. Toxicology 2003;192:37-48 (Pubitemid 37153342)
-
(2003)
Toxicology
, vol.192
, Issue.1
, pp. 37-48
-
-
Johnson, T.N.1
-
57
-
-
33645821243
-
Pharmacological research in pediatrics: From neonates to adolescents
-
Rakhmanina NY, van den Anker JN. Pharmacological research in pediatrics: from neonates to adolescents. Adv Drug Deliv Rev 2006;58:4-14
-
(2006)
Adv Drug Deliv Rev
, vol.58
, pp. 4-14
-
-
Rakhmanina, N.Y.1
Van Den Anker, J.N.2
-
58
-
-
33845741225
-
Physiology-based versus allometric scaling of clearance in children; An eliminating process based comparison
-
Edgington AN, Willman W. Physiology-based versus allometric scaling of clearance in children; an eliminating process based comparison. Paediatr Perinat Drug Ther 2006;7:146-53
-
(2006)
Paediatr Perinat Drug Ther
, vol.7
, pp. 146-53
-
-
Edgington, A.N.1
Willman, W.2
-
60
-
-
0033020642
-
Glucuronidation in humans. Pharmacogenetic and developmental aspects
-
DOI 10.2165/00003088-199936060-00005
-
de Wildt SN, Kearns GL, Leeder JS, et al. Glucuronidation in humans -Pharmacogenetic and developmental aspects. Clin Pharmacokinet 1999;36:439-52 (Pubitemid 29317491)
-
(1999)
Clinical Pharmacokinetics
, vol.36
, Issue.6
, pp. 439-452
-
-
De Wildt, S.N.1
Kearns, G.L.2
Leeder, J.S.3
Van Den Anker, J.N.4
-
61
-
-
34249649717
-
Malnutrition and infection: Complex mechanisms and global impacts
-
DOI 10.1371/journal.pmed.0040115
-
Schaible UE, Kaufmann SHE. Malnutrition and infection: complex mechanisms and global impacts. PLoS Med 2007;4:0806-12 (Pubitemid 46842571)
-
(2007)
PLoS Medicine
, vol.4
, Issue.5
, pp. 0806-0812
-
-
Schaible, U.E.1
Kaufmann, S.H.E.2
-
62
-
-
73849142431
-
Pathophysiological changes that affect drug disposition in protein-energy malnourished children
-
Oshikoya KA, Senbanjo IO. Pathophysiological changes that affect drug disposition in protein-energy malnourished children. Nutr Metab 2009;50:6
-
(2009)
Nutr Metab
, vol.50
, pp. 6
-
-
Oshikoya, K.A.1
Senbanjo, I.O.2
-
63
-
-
67949120449
-
Impact of child malnutrition on the specific anti-plasmodium falciparum antibody response
-
Fillol F, Sarr J, Boulanger D, et al. Impact of child malnutrition on the specific anti-plasmodium falciparum antibody response. Malar J 2009;8:116
-
(2009)
Malar J
, vol.8
, pp. 116
-
-
Fillol, F.1
Sarr, J.2
Boulanger, D.3
-
64
-
-
0036240963
-
Increased risk for malaria in chronically malnuurished children under 5 years of age in rural gambia
-
DOI 10.1093/tropej/48.2.78
-
Deen JL, Walraven GEL, von Seidlein L. Increased risk for malaria in chronically malnourished children under 5 years of age in Rural Gambia. J Trop Pediatr 2002;48:78-83 (Pubitemid 34461029)
-
(2002)
Journal of Tropical Pediatrics
, vol.48
, Issue.2
, pp. 78-83
-
-
Deen, J.L.1
Walraven, G.E.L.2
Von Seidlein, L.3
-
65
-
-
66149144295
-
Reduced efficacy of intermittent preventive treatment of malaria in malnourished children
-
Danquah I, Dietz E, Zanger P, et al. Reduced efficacy of intermittent preventive treatment of malaria in malnourished children. Antimicrob Agents Chemother 2009;53:1753-9
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 1753-9
-
-
Danquah, I.1
Dietz, E.2
Zanger, P.3
-
66
-
-
33846105531
-
Artemether/lumefantrine in the treatment of uncomplicated falciparum malaria
-
DOI 10.1517/14656566.8.1.75
-
Kokwaro G, Mwai L, Nzila A. Artemether/lumefantrine in the treatment of uncomplicated falciparum malaria. Expert Opin Pharmacother 2007;8:75-94 (Pubitemid 46070831)
-
(2007)
Expert Opinion on Pharmacotherapy
, vol.8
, Issue.1
, pp. 75-94
-
-
Kokwaro, G.1
Mwai, L.2
Nzila, A.3
-
67
-
-
0036900184
-
Maldigestion and malabsorption of dietary lipid during severe childhood malnutrition
-
DOI 10.1136/adc.87.6.522
-
Murphy JL, Badaloo AV, Chambers B, et al. Maldigestion and malabsorption of dietary lipid during severe childhood malnutrition. Arch Dis Child 2002;87:522-5 (Pubitemid 35440705)
-
(2002)
Archives of Disease in Childhood
, vol.87
, Issue.6
, pp. 522-525
-
-
Murphy, J.L.1
Badaloo, A.V.2
Chambers, B.3
Forrester, T.E.4
Wootton, S.A.5
Jackson, A.A.6
-
68
-
-
77957670976
-
A systematic review of pharmacokinetics studies in children with protein-energy malnutrition
-
Oshikoya KA, Sammons HM, Choonara I. A systematic review of pharmacokinetics studies in children with protein-energy malnutrition. Eur J Clin Pharmacol 2010;66:1025-35
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 1025-35
-
-
Oshikoya, K.A.1
Sammons, H.M.2
Choonara, I.3
-
69
-
-
0345148422
-
Suppression of Rat Hepatic Cytochrome P450s by protein-calorie malnutrition: Complete or partial restoration by cysteine or methionine supplementation
-
Cho MK, Kim YG, Lee MG, et al. Suppression of Rat Hepatic Cytochrome P450s by protein-calorie malnutrition: complete or partial restoration by cysteine or methionine supplementation. Arch Biochem Biophys 1999;372:150-8
-
(1999)
Arch Biochem Biophys
, vol.372
, pp. 150-8
-
-
Cho, M.K.1
Kim, Y.G.2
Lee, M.G.3
-
70
-
-
0021359811
-
Control of glucuronidation during hypoxia. Limitation by UDP-glucose pyrophosphorylase
-
Aw TY, Jones DP. Control of glucuronidation during hypoxia -limitation by udp-glucose pyrophosphorylase. Biochem J 1984;219:707-12 (Pubitemid 14141731)
-
(1984)
Biochemical Journal
, vol.219
, Issue.3
, pp. 707-712
-
-
Aw, T.Y.1
Jones, D.P.2
-
71
-
-
0025324937
-
The effect of dietary energy and protein deficiency on drug metabolism
-
DOI 10.1007/BF00278583
-
Hamberg O, Ovesen L, Dorfeldt A, et al. The effect of dietary energy and protein-deficiency on drug-metabolism. Eur J Clin Pharmacol 1990;38:567-70 (Pubitemid 20206029)
-
(1990)
European Journal of Clinical Pharmacology
, vol.38
, Issue.6
, pp. 567-570
-
-
Hamberg, O.1
Ovesen, L.2
Dorfeldt, A.3
Loft, S.4
Sonne, J.5
-
72
-
-
77953830070
-
Global impacts of human mineral malnutrition
-
Stein AJ. Global impacts of human mineral malnutrition. Plant Soil 2009;335:133-54
-
(2009)
Plant Soil
, vol.335
, pp. 133-54
-
-
Stein, A.J.1
-
73
-
-
0020471128
-
Mechanisms of anemia in protein-energy malnutrition in Johannesburg
-
Macdougall LG, Moodley G, Eyberg C, et al. Mechanisms of anemia in protein-energy malnutrition in Johannesburg. Am J Clin Nutr 1982;35:229-35 (Pubitemid 12121020)
-
(1982)
American Journal of Clinical Nutrition
, vol.35
, Issue.2
, pp. 229-235
-
-
Macdougall, L.G.1
Moodley, G.2
Eyberg, C.3
Quirk, M.4
-
74
-
-
77957670976
-
A systematic review of pharmacokinetics studies in children with protein-energy malnutrition
-
Oshikoya K, Sammons H, Choonara I. A systematic review of pharmacokinetics studies in children with protein-energy malnutrition. Eur J Clin Pharmacol 2010;66:1025-35
-
(2010)
Eur J Clin Pharmacol
, vol.66
, pp. 1025-35
-
-
Oshikoya, K.1
Sammons, H.2
Choonara, I.3
-
75
-
-
34249012765
-
New developments in synthetic peroxidic drugs as artemisinin mimics
-
DOI 10.1016/j.drudis.2007.04.009, PII S1359644607001870
-
Jefford CW. New developments in synthetic peroxidic drugs as artemisinin mimics. Drug Discov Today 2007;12:487-95 (Pubitemid 46783690)
-
(2007)
Drug Discovery Today
, vol.12
, Issue.11-12
, pp. 487-495
-
-
Jefford, C.W.1
-
76
-
-
4344630762
-
Identification of an antimalarial synthetic trioxolane drug development candidate
-
DOI 10.1038/nature02779
-
Vennerstrom JL, Arbe-Barnes S, Brun R, et al. Identification of an antimalarial synthetic trioxolane drug development candidate. Nature 2004;430:900-4 (Pubitemid 39119218)
-
(2004)
Nature
, vol.430
, Issue.7002
, pp. 900-904
-
-
Vennerstrom, J.L.1
Arbe-Barnes, S.2
Brun, R.3
Charman, S.A.4
Chiu, F.C.K.5
Chollet, J.6
Dong, Y.7
Dorn, A.8
Hunziker, D.9
Matile, H.10
McIntosh, K.11
Padmanilayam, M.12
Santo Tomas, J.13
Scheurer, C.14
Scorneaux, B.15
Tang, Y.16
Urwyler, H.17
Wittlin, S.18
Charman, W.H.19
|