Biliary metabolites of β-artemether in rats: Biotransformations of an antimalarial endoperoxide

Drug Metabolism and Disposition

Volumn 28, Issue 2, 2000, Pages 209-217

  Maggs, James L ^a   Bishop, Laurence P D ^a   Edwards, Geoffrey ^a,b   O'Neill, Paul M ^a   Ward, Stephen A ^a   Winstanley, Peter A ^a   Park, B Kevin ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

^b LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; BETA ARTEMETHER; DIHYDROARTEMISININ; DRUG METABOLITE; GLUCURONIDE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG BILE LEVEL; DRUG GLUCURONIDATION; DRUG HYDROXYLATION; DRUG METABOLISM; DRUG STRUCTURE; DRUG TRANSFORMATION; ISOMER; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REACTION ANALYSIS;

ANIMALS; ANTIMALARIALS; ARTEMISININS; BILE; BIOTRANSFORMATION; FREE RADICALS; GLUCURONIDES; HYDROLYSIS; HYDROXYLATION; ISOMERISM; MALE; MASS SPECTROMETRY; PEROXIDES; RATS; RATS, WISTAR; SESQUITERPENES; TISSUE DISTRIBUTION;

ANIMALIA; RATTUS NORVEGICUS;

EID: 0033959522     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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