Identification of neural targets for the treatment of psychiatric disorders: The role of functional neuroimaging

Neurosurgery Clinics of North America

Volumn 22, Issue 2, 2011, Pages 279-305

  Vago, David R ^a   Epstein, Jane ^a   Catenaccio, Eva ^a   Stern, Emily ^b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Depression; Neurocircuitry; Neuroimaging; Psychiatric disorders

Indexed keywords

4 AMINOBUTYRIC ACID; ANTIDEPRESSANT AGENT; CHOLINE; GLUCOCORTICOID RECEPTOR;

ABLATION THERAPY; AMYGDALOID NUCLEUS; ANTERIOR CINGULATE; BASAL GANGLION; BRAIN CORTEX; BRAIN DEPTH STIMULATION; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; BRAIN LEVEL; BRAIN MAPPING; BRAIN REGION; CEREBROSPINAL FLUID; CLINICAL FEATURE; CORPUS STRIATUM; DEPRESSION; DIAGNOSTIC VALUE; DISEASE COURSE; DRUG TARGETING; FRONTAL LOBE; FUNCTIONAL ASSESSMENT; HIPPOCAMPUS; HISTORY OF MEDICINE; HUMAN; INSULA; MENTAL DISEASE; MENTAL FUNCTION; NEUROCHEMISTRY; NEUROIMAGING; NEUROPATHOLOGY; NEUROPSYCHIATRY; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; REVIEW; STEREOTAXIC SURGERY; THALAMUS DORSOMEDIAL NUCLEUS;

BRAIN CHEMISTRY; HISTORY, 18TH CENTURY; HISTORY, 19TH CENTURY; HISTORY, 20TH CENTURY; HISTORY, ANCIENT; HUMANS; MENTAL DISORDERS; MODELS, NEUROLOGICAL; NERVE NET; NERVOUS SYSTEM; NEUROLOGY; NEUROPSYCHIATRY; NEUROSURGERY; NEUROSURGICAL PROCEDURES; PHRENOLOGY; PSYCHOSURGERY;

EID: 79952837473     PISSN: 10423680     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nec.2011.01.003     Document Type: Review

References (239)

1. Jackson S.W. Melancholia and depression: from Hippocratic times to modern times 1986, Yale University Press, New Haven (CT).
2. Kutzer M. Tradition, metaphors, anatomy of the brain: the physiology of insanity in the late XVIth and XVIIth centuries, in essays in the history of the physiological sciences: Proceedings of a symposium held at the University Louis Pasteur 1993, 99-116. The Wellcome Institute Series in the History of Medicine, Atlanta (GA). C. Debru (Ed.).
3. Nicolaidis S. Depression and neurosurgery: past, present, and future. Metabolism 2005, 54(5 Suppl 1):28-32.
4. Siegel R.E. Galen on psychology, psychopathology and function and diseases of the nervous system 1973, Karger, Basel (Switzerland).
5. Clarke E., O'Malley C.D. The human brain and spinal cord: a historical study illustrated by writings from antiquity to the twentieth century 1996, Norman neurosciences series; no. 2, Norman Publishers, San Francisco (CA).
6. Gross C.G. Brain, vision, memory: tales in the history of neuroscience 1998, MIT Press, Cambridge (MA).
7. Finger S. Origins of neuroscience: a history of explorations into brain function 1994, Oxford University Press, New York.
8. Zola-Morgan S. Localization of brain function: the legacy of Franz Joseph Gall (1758-1828). Annu Rev Neurosci 1995, 18(1):359-383.
9. Harrington A. Beyond phrenology: localization theory in the modern era. The enchanted loom: chapters in the history of neuroscience 1991, 207-239. Oxford University Press, New York. P. Corsi (Ed.).
10. Bouillaud M.J. Traite clinique et physiologique de l'encephalite ou inflammation du cerveau, et de ses suites 1825, Bailiere, Paris.
11. Finger S. Minds behind the brain: a history of the pioneers and their discoveries 2000, Oxford University Press, Oxford (UK).
12. Farah M.J., Feinberg T.E. Patient-based approaches to cognitive neuroscience 2000, MIT Press, Cambridge (MA).
13. Finger S., Michael F.B., Aminoff J., et al. Chapter 10. The birth of localization theory. History of neurology 2009, 117-128. Elsevier, New York. S. Finger, F. Boller, K. Tyler (Eds.).
14. Damasio H., Grabowski T., Frank R., et al. The return of Phineas Gage: clues about the brain from the skull of a famous patient. Science 1994, 264(5162):1102-1105.
15. Ratiu P., Talos I.F., Haker S., et al. The tale of Phineas Gage, digitally remastered. J Neurotrauma 2004, 21(5):637-643.
16. McHenry L.C. Garrison's history of neurology 1969, Charles C Thomas, Springfield (IL).
17. Jackson J.H. Selected writings of John Hughlings Jackson 1931, Hodder and Stoughton, London.
18. Maclean P.D. The limbic system and its hippocampal formation; studies in animals and their possible application to man. J Neurosurg 1954, 11(1):29-44.
19. Papez J.W. A proposed mechanism of emotion. 1937. J Neuropsychiatry Clin Neurosci 1995, 7(1):103-112.
20. Cannon W.B. The James-Lange theory of emotions: a critical examination and an alternative theory. Am J Psychol 1927, 39:106-124.
21. Alheid G.F., Heimer L. New perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: the striatopallidal, amygdaloid, and corticopetal components of substantia innominata. Neuroscience 1988, 27(1):1-39.
22. Ongur D., Price J.L. The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans. Cereb Cortex 2000, 10(3):206-219.
23. Amaral D.G., Price J.L. Amygdalo-cortical projections in the monkey (Macaca fascicularis). J Comp Neurol 1984, 230(4):465-496.
24. Krettek J.E., Price J.L. An audioradiographic study of projections from the amygdaloid complex to the thalamus and cerebral cortex. J Comp Neurol 1977, 172:723-752.
25. Nauta W.J. Fibre degeneration following lesions of the amygdaloid complex in the monkey. J Anat 1961, 95:515-531.
26. Nauta W.J., Feirtag M. The organization of the brain. Sci Am 1979, 241(3):88-111.
27. Heimer L. Pathways in the brain. Sci Am 1971, 225:48-60.
28. Gray T.S. Functional and anatomical relationships among the amygdala, basal forebrain, ventral striatum, and cortex: an integrative discussion. Advancing from the ventral striatum to the extended amygdala 1999, 439-445. The New York Academy of Sciences, New York. J.F. McGinty (Ed.).
29. De Olmos J.S., Heimer L. The concepts of the ventral striatopallidal system and extended amygdala. Advancing from the ventral striatum to the extended amygdala 1999, 1-33. The New York Academy of Sciences, New York. J.F. McGinty (Ed.).
30. Gardner H.E. The mind's new science: a history of the cognitive revolution 1987, Basic Books, New York.
31. Stein D.J. Cognitive science and psychiatry: an overview. Integr Psychiatry 1993, 9(1):13-24.
32. Benson D.F. Neuropsychiatry and behavioral neurology: past, present, and future. J Neuropsychiatry Clin Neurosci 1996, 8(3):351-357.
33. Geschwind N. Disconnexion syndromes in animals and man: Part I. 1965. Neuropsychol Rev 2010, 20(2):128-157.
34. Ross E.D. Intellectual origins and theoretical framework of behavioral neurology: a response to Michael R. Trimble. Neuropsychiatry Neuropsychol Behav Neurol 1993, 6(1):65-67.
35. LeDoux J.E. The emotional brain: the mysterious underpinnings of emotional life 1996, Simon & Schuster, New York.
36. McGaugh J.L., Roozendaal B., Cahill L. Modulation of memory storage by stress hormones and the amygdaloid complex. The new cognitive neurosciences 2000, 1081-1098. MIT Press, Cambridge (MA). M.S. Gazzaniga (Ed.).
37. Ono T., Nishijo H. Neurophysiological basis of emotion in primates: neuronal responses in the monkey amygdala and anterior cingulate cortex. The new cognitive neurosciences 2000, 1099-1114. MIT Press, Cambridge (MA). M.S. Gazzaniga (Ed.).
38. Robbins T.W., Everitt B.J. Neurobehavioural mechanisms of reward and motivation. Curr Opin Neurobiol 1996, 6(2):228-236.
39. Rolls E.T. The orbitofrontal cortex. The prefrontal cortex: executive and cognitive functions 1998, 67-86. Oxford University Press, New York. A.C. Roberst (Ed.).
40. McEwen B.S. Stress and hippocampal plasticity. Annu Rev Neurosci 1999, 22(1):105-122.
41. Brothers L. The social brain: a project for integrating primate behavior and neuropsychiatry in a new domain. Concepts Neurosci 1990, 1(1):27-51.
42. Cosmides L., Tooby J. The cognitive neurosciences of social reasoning. The new cognitive neurosciences 2000, 1259-1270. MIT Press, Cambridge (MA). M.S. Gazzaniga (Ed.).
43. Jacoby R.J., Levy R., Dawson J.M. Computed tomography in the elderly: I. The normal population. Br J Psychiatry 1980, 136:249-255.
44. Rangel-Guerra R.A., Perez-Payan H., Minkoff L., et al. Nuclear magnetic resonance in bipolar affective disorders. AJNR Am J Neuroradiol 1983, 4(3):229-231.
45. Huettel S.A., Song A.W., McCarthy G. Functional magnetic resonance imaging 2008, Sinauer Associates, Sunderland (MA). 2nd edition.
46. Drevets W.C., Price J.L., Furey M.L. Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. Brain Struct Funct 2008, 213(1/2):93-118.
47. Phillips M.L., Drevets W.C., Rauch S.L., et al. Neurobiology of emotion perception II: implications for major psychiatric disorders. Biol Psychiatry 2003, 54(5):515-528.
48. Price J.L., Drevets W.C. Neurocircuitry of mood disorders. Neuropsychopharmacology 2010, 35(1):192-216.
49. Dolan R.J., Poynton A.M., Bridges P.K., et al. Altered magnetic resonance white-matter T1 values in patients with affective disorder. Br J Psychiatr 1990, 157:107-110.
50. Soares J.C., Mann J.J. The anatomy of mood disorders - review of structural neuroimaging studies. Biol Psychiatry 1997, 41(1):86-106.
51. Dougherty D., Rauch S.L. Neuroimaging and neurobiological models of depression. Harv Rev Psychiatry 1997, 5(3):138-159.
52. Bench C.J., Dolan R.J., Friston K.J., et al. Positron emission tomography in the study of brain metabolism in psychiatric and neuropsychiatric disorders. Br J Psychiatry Suppl 1990, 9:82-95.
53. Sheline Y.I. Neuroimaging studies of mood disorder effects on the brain. Biol Psychiatry 2003, 54(3):338-352.
54. Nestler E.J., Carlezon W.A. The mesolimbic dopamine reward circuit in depression. Biol Psychiatry 2006, 59(12):1151-1159.
55. McEwen B.S., Magarinos A.M. Stress and hippocampal plasticity: implications for the pathophysiology of affective disorders. Hum Psychopharmacol 2001, 16(S1):S7-S19.
56. Mayberg H.S., McGinnis S. Brain mapping: the application, mood and emotions. Brain mapping: the systems 2000, 491-521. Academic Press, San Francisco (CA). A.W. Toga, J.C. Mazziotta (Eds.).
57. Liu D., Diorio J., Tannenbaum B., et al. Maternal care, hippocampal glucocorticoid receptors, and hypothalamic-pituitary-adrenal responses to stress. Science 1997, 277(5332):1659-1662.
58. Sheline Y.I. Hippocampal atrophy in major depression: a result of depression-induced neurotoxicity?. Mol Psychiatry 1996, 1(4):298-299.
59. DeCarolis N.A., Eisch A.J. Hippocampal neurogenesis as a target for the treatment of mental illness: a critical evaluation. Neuropharmacology 2010, 58(6):884-893.
60. Burke H.M., Davis M.C., Otte C., et al. Depression and cortisol responses to psychological stress: a meta-analysis. Psychoneuroendocrinology 2005, 30(9):846-856.
61. Daley S.E., Hammen C., Rao U. Predictors of first onset and recurrence of major depression in young women during the 5 years following high school graduation. J Abnorm Psychol 2000, 109(3):525-533.
62. Kendler K.S., Karkowski L.M., Prescott C.A. Causal relationship between stressful life events and the onset of major depression. Am J Psychiatr 1999, 156(6):837-841.
63. Hammen C., Davila J., Brown G., et al. Psychiatric history and stress: predictors of severity of unipolar depression. J Abnorm Psychol 1992, 101(1):45-52.
64. Strakowski S.M., Adler C.M., DelBello M.P. Volumetric MRI studies of mood disorders: do they distinguish unipolar and bipolar disorder?. Bipolar Disord 2002, 4(2):80-88.
65. Krishnan K.R., McDonald W.M., Tupler L.A. Neuropathology in affective illness. Am J Psychiatr 1993, 150(10):1568-1569.
66. McDonald W.M., Krishnan K.R. Magnetic resonance in patients with affective illness. Eur Arch Psychiatry Clin Neurosci 1992, 241(5):283-290.
67. Drevets W.C., Gadde K., Krishnan K.R. Neuroimaging studies of mood disorders. Neurobiology of mental illness 2004, 461-480. Oxford University Press, New York. D.S. Charney, E.J. Nestler (Eds.).
68. Mayberg H.S. Defining the neural circuitry of depression: toward a new nosology with therapeutic implications. Biol Psychiatry 2007, 61(6):729-730.
69. Rauch S.L. Neuroimaging and neurocircuitry models pertaining to the neurosurgical treatment of psychiatric disorders. Neurosurg Clin N Am 2003, 14(2):213-223. vii-viii.
70. Lorenzetti V., Allen N.B., Fornito A., et al. Structural brain abnormalities in major depressive disorder: a selective review of recent MRI studies. J Affect Disord 2009, 117(1-2):1-17.
71. Ongur D., Ferry A.T., Price J.L. Architectonic subdivision of the human orbital and medial prefrontal cortex. J Comp Neurol 2003, 460(3):425-449.
72. Davidson R.J., Irwin W. The functional neuroanatomy of emotion and affective style. Trends Cogn Sci 1999, 3(1):11-21.
73. Downhill J.E., Robinson R.G. Longitudinal assessment of depression and cognitive impairment following stroke. J Nerv Ment Dis 1994, 182(8):425-431.
74. Gainotti G. Emotional behavior and hemispheric side of the lesion. Cortex 1972, 8(1):41-55.
75. Davidson R.J. Anxiety and affective style: role of prefrontal cortex and amygdala. Biol Psychiatry 2002, 51(1):68-80.
76. Davidson R.J., Lewis D.A., Alloy L.B., et al. Neural and behavioral substrates of mood and mood regulation. Biol Psychiatry 2002, 52(6):478-502.
77. Starkstein S.E., Mayberg H.S., Berthier M.L., et al. Mania after brain injury: neuroradiological and metabolic findings. Ann Neurol 1990, 27(6):652-659.
78. Robinson R.G., Downhill J.E. Lateralization of psychopathology in response to focal brain injury. Brain asymmetry 1995, 693-711. MIT Press, Cambridge (MA). R.J. Davidson, K. Hugdahl (Eds.).
79. Fitzgerald P.B., Oxley T.J., Laird A.R., et al. An analysis of functional neuroimaging studies of dorsolateral prefrontal cortical activity in depression. Psychiatry Res 2006, 148(1):33-45.
80. Davidson R.J., Pizzagalli D., Nitschke J.B., et al. Depression: perspectives from affective neuroscience. Annu Rev Psychol 2002, 53:545-574.
81. Cerullo M.A., Adler C.M., Delbello M.P., et al. The functional neuroanatomy of bipolar disorder. Int Rev Psychiatry 2009, 21(4):314-322.
82. Emsell L., McDonald C. The structural neuroimaging of bipolar disorder. Int Rev Psychiatry 2009, 21(4):297-313.
83. Fleck D.E., Nandagopal J., Cerullo M.A., et al. Morphometric magnetic resonance imaging in psychiatry. Top Magn Reson Imaging 2008, 19(2):131-142.
84. Hallahan B., Newell J., Soares J.C., et al. Structural magnetic resonance imaging in bipolar disorder: an international collaborative mega-analysis of individual adult patient data. Biol Psychiatry 2011, 69(4):326-335.
85. Adler C.M., DelBello M.P., Jarvis K., et al. Voxel-based study of structural changes in first-episode patients with bipolar disorder. Biol Psychiatry 2007, 61(6):776-781.
86. Bremner J.D. Structural changes in the brain in depression and relationship to symptom recurrence. CNS Spectr 2002, 7(2):129-130. 135-9.
87. Lai T., Payne M.E., Byrum C.E., et al. Reduction of orbital frontal cortex volume in geriatric depression. Biol Psychiatry 2000, 48(10):971-975.
88. Rajkowska G., Miguel-Hidalgo J.J., Wei J., et al. Morphometric evidence for neuronal and glial prefrontal cell pathology in major depression. Biol Psychiatry 1999, 45(9):1085-1098.
89. Ekman C.J., Lind J., Rydén E., et al. Manic episodes are associated with grey matter volume reduction - a voxel-based morphometry brain analysis. Acta Psychiatr Scand 2010, 122:507-515.
90. Li C.T., Lin C.P., Chou K.H., et al. Structural and cognitive deficits in remitting and non-remitting recurrent depression: a voxel-based morphometric study. Neuroimage 2010, 50(1):347-356.
91. Critchley H.D., Mathias C.J., Josephs O., et al. Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence. Brain 2003, 126(Pt 10):2139-2152.
92. Mayberg H.S., Brannan S.K., Mahurin R.K., et al. Cingulate function in depression: a potential predictor of treatment response. Neuroreport 1997, 8(4):1057-1061.
93. Ressler K.J., Mayberg H.S. Targeting abnormal neural circuits in mood and anxiety disorders: from the laboratory to the clinic. Nat Neurosci 2007, 10(9):1116-1124.
94. Bench C.J., Friston K.J., Brown R.G., et al. Regional cerebral blood flow in depression measured by positron emission tomography: the relationship with clinical dimensions. Psychol Med 1993, 23(3):579-590.
95. Botteron K.N., Raichle M.E., Drevets W.C., et al. Volumetric reduction in left subgenual prefrontal cortex in early onset depression. Biol Psychiatry 2002, 51(4):342-344.
96. Coryell W., Nopoulos P., Drevets W., et al. Subgenual prefrontal cortex volumes in major depressive disorder and schizophrenia: diagnostic specificity and prognostic implications. Am J Psychiatr 2005, 162(9):1706-1712.
97. Drevets W.C., Savitz J., Trimble M. The subgenual anterior cingulate cortex in mood disorders. CNS Spectr 2008, 13(8):663-681.
98. Ebert D., Ebmeier K.P. The role of the cingulate gyrus in depression: from functional anatomy to neurochemistry. Biol Psychiatry 1996, 39(12):1044-1050.
99. Hastings R.S., Parsey R.V., Oquendo M.A., et al. Volumetric analysis of the prefrontal cortex, amygdala, and hippocampus in major depression. Neuropsychopharmacology 2004, 29(5):952-959.
100. Drevets W.C., Price J.L., Simpson J.R., et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 1997, 386(6627):824-827.
101. Drevets W.C., Ongur D., Price J.L. Neuroimaging abnormalities in the subgenual prefrontal cortex: implications for the pathophysiology of familial mood disorders. Mol Psychiatry 1998, 3(3):220-226. 190-1.
102. Ongur D., Drevets W.C., Price J.L. Glial reduction in the subgenual prefrontal cortex in mood disorders. Proc Natl Acad Sci U S A 1998, 95(22):13290-13295.
103. Rajkowska G. Postmortem studies in mood disorders indicate altered numbers of neurons and glial cells. Biol Psychiatry 2000, 48(8):766-777.
104. McKinnon M.C., Yucel K., Nazarov A., et al. A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder. J Psychiatry Neurosci 2009, 34(1):41-54.
105. Bremner J.D., Narayan M., Anderson E.R., et al. Hippocampal volume reduction in major depression. Am J Psychiatr 2000, 157(1):115-118.
106. Campbell S., Marriott M., Nahmias C., et al. Lower hippocampal volume in patients suffering from depression: a meta-analysis. Am J Psychiatr 2004, 161(4):598-607.
107. Cole J., Toga A.W., Hojatkashani C., et al. Subregional hippocampal deformations in major depressive disorder. J Affect Disord 2010, 126(1/2):272-277.
108. de Asis J.M., Stern E., Alexopoulos G.S., et al. Hippocampal and anterior cingulate activation deficits in patients with geriatric depression. Am J Psychiatr 2001, 158(8):1321-1323.
109. Vakili K., Pillay S.S., Lafer B., et al. Hippocampal volume in primary unipolar major depression: a magnetic resonance imaging study. Biol Psychiatry 2000, 47(12):1087-1090.
110. Neumeister A., Charney D.S., Drevets W.C. Hippocampus, VI. Depression and the hippocampus. Am J Psychiatr 2005, 162(6):1057.
111. Feder A., Nestler E.J., Charney D.S. Psychobiology and molecular genetics of resilience. Nat Rev Neurosci 2009, 10(6):446-457.
112. Frodl T., Meisenzahl E.M., Zetzsche T., et al. Hippocampal changes in patients with a first episode of major depression. Am J Psychiatr 2002, 159(7):1112-1118.
113. Drevets W., Gadde K., Krishnan K. Neuroimaging studies of mood disorders. The neurobiological foundation of mental illness 2004, 461-490. Oxford University Press, New York. D.S. Charney, E.J. Nestler, B.J. Bunney (Eds.).
114. Drevets W.C. Neuroimaging abnormalities in the amygdala in mood disorders. Ann N Y Acad Sci 2003, 985:420-444.
115. Sheline Y.I., Gado M.H., Price J.L. Amygdala core nuclei volumes are decreased in recurrent major depression. Neuroreport 1998, 9(9):2023-2028.
116. Bowley M.P., Drevets W.C., Ongür D., et al. Low glial numbers in the amygdala in major depressive disorder. Biol Psychiatry 2002, 52(5):404-412.
117. Krishnan K.R., McDonald W.M., Escalona P.R., et al. Magnetic resonance imaging of the caudate nuclei in depression. Preliminary observations. Arch Gen Psychiatry 1992, 49(7):553-557.
118. Baumann B., Danos P., Krell D., et al. Reduced volume of limbic system-affiliated basal ganglia in mood disorders: preliminary data from a postmortem study. J Neuropsychiatry Clin Neurosci 1999, 11(1):71-78.
119. Carlson P.J., Singh J.B., Zarate C.A., et al. Neural circuitry and neuroplasticity in mood disorders: insights for novel therapeutic targets. NeuroRx 2006, 3(1):22-41.
120. Krishnan K.R., McDonald W.M., Doraiswamy P.M., et al. Neuroanatomical substrates of depression in the elderly. Eur Arch Psychiatry Clin Neurosci 1993, 243(1):41-46.
121. Aylward E.H., Roberts-Twillie J.V., Barta P.E., et al. Basal ganglia volumes and white matter hyperintensities in patients with bipolar disorder. Am J Psychiatr 1994, 151(5):687-693.
122. Bonelli R.M., Kapfhammer H.P., Pillay S.S., et al. Basal ganglia volumetric studies in affective disorder: what did we learn in the last 15 years?. J Neural Transm 2006, 113(2):255-268.
123. Bhatia K.P., Daniel S.E., Marsden C.D. Familial parkinsonism with depression: a clinicopathological study. Ann Neurol 1993, 34(6):842-847.
124. Martinelli P., Giuliani S., Ippoliti M., et al. Familial idiopathic strio-pallido-dentate calcifications with late onset extrapyramidal syndrome. Mov Disord 1993, 8(2):220-222.
125. Drevets W.C. Functional neuroimaging studies of depression: the anatomy of melancholia. Annu Rev Med 1998, 49:341-361.
126. Baxter L.R., Phelps M.E., Mazziotta J.C., et al. Cerebral metabolic rates for glucose in mood disorders. Studies with positron emission tomography and fluorodeoxyglucose F 18. Arch Gen Psychiatry 1985, 42(5):441-447.
127. Buchsbaum M.S. Brain imaging in the search for biological markers in affective disorder. J Clin Psychiatr 1986, 47(Suppl):7-12.
128. Ketter T.A., George M.S., Kimbrell T.A., et al. Functional brain imaging, limbic function, and affective disorders. Neuroscientist 1996, 2(1):55-65.
129. Bench C.J., Friston K.J., Brown R.G., et al. The anatomy of melancholia-focal abnormalities of cerebral blood flow in major depression. Psychol Med 1992, 22(3):607-615.
130. Mayberg H.S. Limbic-cortical dysregulation: a proposed model of depression. J Neuropsychiatry Clin Neurosci 1997, 9(3):471-481.
131. Goldapple K., Segal Z., Garson C., et al. Modulation of cortical-limbic pathways in major depression: treatment-specific effects of cognitive behavior therapy. Arch Gen Psychiatry 2004, 61(1):34-41.
132. Bewernick B.H., Hurlemann R., Matusch A., et al. Nucleus accumbens deep brain stimulation decreases ratings of depression and anxiety in treatment-resistant depression. Biol Psychiatry 2010, 67(2):110-116.
133. Blumberg H.P., Stern E., Martinez D., et al. Increased anterior cingulate and caudate activity in bipolar mania. Biol Psychiatry 2000, 48(11):1045-1052.
134. Blumberg H.P., Stern E., Ricketts S., et al. Rostral and orbital prefrontal cortex dysfunction in the manic state of bipolar disorder. Am J Psychiatr 1999, 156(12):1986-1988.
135. Thayer J.F., Lane R.D. A model of neurovisceral integration in emotion regulation and dysregulation. J Affect Disord 2000, 61(3):201-216.
136. Bush G., Luu P., Posner M.I. Cognitive and emotional influences in anterior cingulate cortex. Trends Cogn Sci 2000, 4(6):215-222.
137. George M.S., Ketter T.A., Parekh P.I., et al. Blunted left cingulate activation in mood disorder subjects during a response interference task (the Stroop). J Neuropsychiatry Clin Neurosci 1997, 9(1):55-63.
138. Pizzagalli D.A., Oakes T.R., Fox A.S., et al. Functional but not structural subgenual prefrontal cortex abnormalities in melancholia. Mol Psychiatry 2004, 9(4):393-405.
139. Mayberg H.S. Clinical correlates of PET- and SPECT-identified defects in dementia. J Clin Psychiatr 1994, 55(Suppl):12-21.
140. Kumar A., Newberg A., Alavi A., et al. Regional cerebral glucose metabolism in late-life depression and Alzheimer disease: a preliminary positron emission tomography study. Proc Natl Acad Sci U S A 1993, 90(15):7019-7023.
141. Liotti M., Mayberg H.S. The role of functional neuroimaging in the neuropsychology of depression. J Clin Exp Neuropsychol 2001, 23(1):121-136.
142. Anand A., Li Y., Wang Y., et al. Activity and connectivity of brain mood regulating circuit in depression: a functional magnetic resonance study. Biol Psychiatry 2005, 57(10):1079-1088.
143. Kumano H., Ida I., Oshima A., et al. Brain metabolic changes associated with predisposition to onset of major depressive disorder and adjustment disorder in cancer patients-a preliminary PET study. J Psychiatr Res 2007, 41(7):591-599.
144. Siegle G.J., Carter C.S., Thase M.E. Use of FMRI to predict recovery from unipolar depression with cognitive behavior therapy. Am J Psychiatr 2006, 163(4):735-738.
145. Kennedy S.H., Evans K.R., Krüger S., et al. Changes in regional brain glucose metabolism measured with positron emission tomography after paroxetine treatment of major depression. Am J Psychiatr 2001, 158(6):899-905.
146. Beauregard M., Leroux J.M., Bergman S., et al. The functional neuroanatomy of major depression: an fMRI study using an emotional activation paradigm. Neuroreport 1998, 9(14):3253-3258.
147. George M.S., Ketter T.A., Parekh P.I., et al. Regional blood-flow correlates of transient self-induced sadness or happiness. Biol Psychiatry 1994, 35(9):647.
148. Fu C.H., Williams S.C., Cleare A.J., et al. Neural responses to sad facial expressions in major depression following cognitive behavioral therapy. Biol Psychiatry 2008, 64(6):505-512.
149. Damasio A.R. Descartes' error: emotion, reason, and the human brain 1994, Avon Books, New York.
150. Osuch E.A., Ketter T.A., Kimbrell T.A., et al. Regional cerebral metabolism associated with anxiety symptoms in affective disorder patients. Biol Psychiatry 2000, 48(10):1020-1023.
151. Drevets W.C., Bogers W., Raichle M.E. Functional anatomical correlates of antidepressant drug treatment assessed using PET measures of regional glucose metabolism. Eur Neuropsychopharmacol 2002, 12(6):527-544.
152. Nobler M.S., Oquendo M.A., Kegeles L.S., et al. Decreased regional brain metabolism after ECT. Am J Psychiatr 2001, 158(2):305-308.
153. Mayberg H.S., Lozano A.M., Voon V., et al. Deep brain stimulation for treatment-resistant depression. Neuron 2005, 45(5):651-660.
154. Mayberg H.S. Modulating dysfunctional limbic-cortical circuits in depression: towards development of brain-based algorithms for diagnosis and optimised treatment. Br Med Bull 2003, 65:193-207.
155. Thomas K.M., Drevets W.C., Dahl R.E., et al. Amygdala response to fearful faces in anxious and depressed children. Arch Gen Psychiatry 2001, 58(11):1057-1063.
156. Siegle G.J., Thompson W., Carter C.S., et al. Increased amygdala and decreased dorsolateral prefrontal BOLD responses in unipolar depression: related and independent features. Biol Psychiatry 2007, 61(2):198-209.
157. Malberg J.E., Eisch A.J., Nestler E.J., et al. Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus. J Neurosci 2000, 20(24):9104-9110.
158. Price J.L., Carmichael S.T., Drevets W.C. Networks related to the orbital and medial prefrontal cortex; a substrate for emotional behavior?. Prog Brain Res 1996, 107:523-536.
159. Baxter L.R., Schwartz J.M., Phelps M.E., et al. Reduction of prefrontal cortex glucose metabolism common to three types of depression. Arch Gen Psychiatry 1989, 46(3):243-250.
160. Strakowski S.M., Delbello M.P., Adler C.M. The functional neuroanatomy of bipolar disorder: a review of neuroimaging findings. Mol Psychiatry 2005, 10(1):105-116.
161. Epstein J., Pan H., Kocsis J.H., et al. Lack of ventral striatal response to positive stimuli in depressed versus normal subjects. Am J Psychiatr 2006, 163(10):1784-1790.
162. McCabe C., Cowen P.J., Harmer C.J. Neural representation of reward in recovered depressed patients. Psychopharmacology (Berl) 2009, 205(4):667-677.
163. Forbes E.E., Dahl R.E. Neural systems of positive affect: relevance to understanding child and adolescent depression?. Dev Psychopathol 2005, 17(3):827-850.
164. Harvey P.O., Pruessner J., Czechowska Y., et al. Individual differences in trait anhedonia: a structural and functional magnetic resonance imaging study in non-clinical subjects. Mol Psychiatry 2007, 12(8):703. 767-75.
165. Beck A.T. The evolution of the cognitive model of depression and its neurobiological correlates. Am J Psychiatr 2008, 165(8):969-977.
166. Dichter G.S., Felder J.N., Petty C., et al. The effects of psychotherapy on neural responses to rewards in major depression. Biol Psychiatry 2009, 66:886-897.
167. Paulus M.P., Stein M.B. Interoception in anxiety and depression. Brain Struct Funct 2010, 214(5/6):451-463.
168. Craig A.D. Interoception: the sense of the physiological condition of the body. Curr Opin Neurobiol 2003, 13(4):500-505.
169. Craig A.D. Emotional moments across time: a possible neural basis for time perception in the anterior insula. Philos Trans R Soc Lond B Biol Sci 2009, 364(1525):1933-1942.
170. Craig A.D. Interoception and emotion. Handbook of emotions 2008, 272-288. Guilford Press, New York. M. Lewis, J.M. Haviland-Jones, L. Feldman Barrett (Eds.).
171. Critchley H.D., Wiens S., Rotshtein P., et al. Neural systems supporting interoceptive awareness. Nat Neurosci 2004, 7(2):189-195.
172. Wiebking C., Bauer A., de Greck M., et al. Abnormal body perception and neural activity in the insula in depression: an fMRI study of the depressed " material me" World J Biol Psychiatry 2010, 11(3):538-549.
173. Lee K.H., Siegle G.J. Common and distinct brain networks underlying explicit emotional evaluation: a meta-analytic study. Soc Cogn Affect Neurosci 2009, [Epub ahead of print].
174. Phillips M.L., Drevets W.C., Rauch S.L., et al. Neurobiology of emotion perception. I: The neural basis of normal emotion perception. Biol Psychiatry 2003, 54(5):504-514.
175. Davidson R.J., Irwin W., Anderle M.J., et al. The neural substrates of affective processing in depressed patients treated with venlafaxine. Am J Psychiatr 2003, 160(1):64-75.
176. Buckner R.L., Andrews-Hanna J.R., Schacter D.L. The brain's default network: anatomy, function, and relevance to disease. Ann N Y Acad Sci 2008, 1124:1-38.
177. Raichle M.E., Snyder A.Z. A default mode of brain function. Proc Natl Acad Sci U S A 2001, 98(2):676-682.
178. Biswal B., Yetkin F.Z., Haughton V.M., et al. Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 1995, 34(4):537-541.
179. Greicius M.D., Supekar K., Menon V., et al. Resting-state functional connectivity reflects structural connectivity in the default mode network. Cereb Cortex 2009, 19(1):72-78.
180. Shehzad Z., Kelly A.M., Reiss P.T., et al. The resting brain: unconstrained yet reliable. Cereb Cortex 2009, 19(10):2209-2229.
181. Andrews-Hanna J.R., Reidler J.S., Huang C., et al. Evidence for the default network's role in spontaneous cognition. J Neurophysiol 2010, 104(1):322-335.
182. Gusnard D.A., Akbudak E., Shulman G.L., et al. Medial prefrontal cortex and self-referential mental activity: relation to a default mode of brain function. Proc Natl Acad Sci U S A 2001, 98(7):4259-4264.
183. Mason M.F., Norton M.I., Van Horn J.D., et al. Wandering minds: the default network and stimulus-independent thought. Science 2007, 315(5810):393-395.
184. Fox M.D., Raichle M.E. Spontaneous fluctuations in brain activity observed with functional magnetic resonance imaging. Nat Rev Neurosci 2007, 8(9):700-711.
185. Northoff G., Heinzel A., de Greck M., et al. Self-referential processing in our brain-a meta-analysis of imaging studies on the self. Neuroimage 2006, 31(1):440-457.
186. Greicius M.D., Flores B.H., Menon V., et al. Resting-state functional connectivity in major depression: abnormally increased contributions from subgenual cingulate cortex and thalamus. Biol Psychiatry 2007, 62(5):429-437.
187. Grimm S., Boesiger P., Beck J., et al. Altered negative BOLD responses in the default-mode network during emotion processing in depressed subjects. Neuropsychopharmacology 2009, 34(4). 932-843.
188. Sheline Y.I., Price JL., Yan Z., et al. Resting-state functional MRI in depression unmasks increased connectivity between networks via the dorsal nexus. Proc Natl Acad Sci U S A 2010, 107(24):11020-11025.
189. Broyd S.J., Demanuele C., Debener S., et al. Default-mode brain dysfunction in mental disorders: a systematic review. Neurosci Biobehav Rev 2009, 33(3):279-296.
190. Berman M.G., Peltier S., Nee D.E., et al. Depression, rumination and the default network. Soc Cogn Affect Neurosci 2010, [Epub ahead of print].
191. Chepenik L.G., Raffo M., Hampson M., et al. Functional connectivity between ventral prefrontal cortex and amygdala at low frequency in the resting state in bipolar disorder. Psychiatry Res 2010, 182(3):207-210.
192. Hasler G., van der Veen J.W., Tumonis T., et al. Reduced prefrontal glutamate/glutamine and gamma-aminobutyric acid levels in major depression determined using proton magnetic resonance spectroscopy. Arch Gen Psychiatry 2007, 64(2):193-200.
193. Horn D.I., Yu C., Steiner J., et al. Glutamatergic and resting-state functional connectivity correlates of severity in major depression - the role of pregenual anterior cingulate cortex and anterior insula. Front Syst Neurosci 2010, 4:33.
194. Ende G., Demirakca T., Tost H. The biochemistry of dysfunctional emotions: proton MR spectroscopic findings in major depressive disorder. Prog Brain Res 2006, 156:481-501.
195. Moore C.M., Breeze J.L., Gruber S.A., et al. Choline, myo-inositol and mood in bipolar disorder: a proton magnetic resonance spectroscopic imaging study of the anterior cingulate cortex. Bipolar Disord 2000, 2(3 Pt 2):207-216.
196. Koenigs M., Grafman J. The functional neuroanatomy of depression: distinct roles for ventromedial and dorsolateral prefrontal cortex. Behav Brain Res 2009, 201(2):239-243.
197. Drevets W.C. Functional anatomical abnormalities in limbic and prefrontal cortical structures in major depression. Prog Brain Res 2000, 126:413-431.
198. Mayberg H.S. Modulating limbic-cortical circuits in depression: targets of antidepressant treatments. Semin Clin Neuropsychiatry 2002, 7(4):255-268.
199. Price J.L. Prefrontal cortical networks related to visceral function and mood. Ann N Y Acad Sci 1999, 877:383-396.
200. Mashour G.A., Walker E.E., Martuza R.L. Psychosurgery: past, present, and future. Brain Res Rev 2005, 48(3):409-419.
201. Delgado M.R., Olsson A., Phelps E.A. Extending animal models of fear conditioning to humans. Biol Psychol 2006, 73(1):39-48.
202. Vallenstein E.S. History of psychosurgery. The history of neurosurgery 1997, 499-516. AANS, Park Ridge (IL). S.H. Greenblatt (Ed.).
203. Bechara A., Damasio H., Damasio A.R. Emotion, decision making and the orbitofrontal cortex. Cereb Cortex 2000, 10(3):295-307.
204. Andersen S.L., Teicher M.H. Stress, sensitive periods and maturational events in adolescent depression. Trends Neurosci 2008, 31(4):183-191.
205. Hare T.A., Tottenham N., Galvan A., et al. Biological substrates of emotional reactivity and regulation in adolescence during an emotional go-nogo task. Biol Psychiatry 2008, 63(10):927-934.
206. Maller J.J., Thomson R.H., Lewis P.M., et al. Traumatic brain injury, major depression, and diffusion tensor imaging: making connections. Brain Res Rev 2010, 64(1):213-240.
207. Charney D.S. Psychobiological mechanisms of resilience and vulnerability: implications for successful adaptation to extreme stress. Am J Psychiatr 2004, 161(2):195-216.
208. Goldman-Rakic P.S. The prefrontal landscape: implications of functional architecture for understanding human mentation and the central executive. Philos Trans R Soc Lond B Biol Sci 1996, 351(1346):1445-1453.
209. Drevets W.C. Neuroimaging and neuropathological studies of depression: implications for the cognitive-emotional features of mood disorders. Curr Opin Neurobiol 2001, 11(2):240-249.
210. Seminowicz D.A., Mayberg H.S., McIntosh A.R., et al. Limbic-frontal circuitry in major depression: a path modeling metanalysis. Neuroimage 2004, 22(1):409-418.
211. Ochsner K.N., Gross J.J. The cognitive control of emotion. Trends Cogn Sci 2005, 9(5):242-249.
212. Larson P.S. Deep brain stimulation for psychiatric disorders. Neurotherapeutics 2008, 5(1):50-58.
213. Nitsche M.A., Boggio P.S., Fregni F., et al. Treatment of depression with transcranial direct current stimulation (tDCS): a review. Exp Neurol 2009, 219(1):14-19.
214. Mayberg H.S. Targeted electrode-based modulation of neural circuits for depression. J Clin Invest 2009, 119(4):717-725.
215. Anderson C.A., Arciniegas D.B. Neurosurgical interventions for neuropsychiatric syndromes. Curr Psychiatry Rep 2004, 6(5):355-363.
216. Feldman R.P., Goodrich J.T. Psychosurgery: a historical overview. Neurosurgery 2001, 48(3):647-657. [discussion: 657-9].
217. Pressman J.D. Last resort: psychosurgery and the limits of medicine 1998, Cambridge University Press, New York.
218. Vallenstein E.S. Great and desperate cures. The rise and decline of psychosurgery and other radical treatments for mental illness 1986, Basic Books, New York.
219. Malhi G.S., Bartlett J.R. Depression: a role for neurosurgery?. Br J Neurosurg 2000, 14(5):415-422. [discussion: 423].
220. Bridges P.K. Investigating psychosurgery. Br J Psychiatr 1990, 157:619.
221. Hodgkiss A.D., Malizia A.L., Bartlett J.R., et al. Outcome after the psychosurgical operation of stereotactic subcaudate tractotomy, 1979-1991. J Neuropsychiatry Clin Neurosci 1995, 7(2):230-234.
222. Feldman R.P., Alterman R.L., Goodrich J.T. Contemporary psychosurgery and a look to the future. J Neurosurg 2001, 95(6):944-956.
223. Marino Junior R., Cosgrove G.R. Neurosurgical treatment of neuropsychiatric illness. Psychiatr Clin North Am 1997, 20(4):933-943.
224. Tye S.J., Frye M.A., Lee K.H. Disrupting disordered neurocircuitry: treating refractory psychiatric illness with neuromodulation. Mayo Clin Proc 2009, 84(6):522-532.
225. Schlaepfer T.E., Cohen M.X., Frick C., et al. Deep brain stimulation to reward circuitry alleviates anhedonia in refractory major depression. Neuropsychopharmacology 2008, 33(2):368-377.
226. Levkovitz Y., Harel E.V., Roth Y., et al. Deep transcranial magnetic stimulation over the prefrontal cortex: evaluation of antidepressant and cognitive effects in depressive patients. Brain Stimul 2009, 2(4):188-200.
227. Rosenberg O., Zangen A., Stryjer R., et al. Response to deep TMS in depressive patients with previous electroconvulsive treatment. Brain Stimul 2010, 3(4):211-217.
228. Slotema C.W., Blom J.D., Hoek H.W., et al. Should we expand the toolbox of psychiatric treatment methods to include repetitive transcranial magnetic stimulation (rTMS)? A meta-analysis of the efficacy of rTMS in psychiatric disorders. J Clin Psychiatr 2010, 71(7):873-884.
229. Nadeau S.E., McCoy K.J., Crucian G.P., et al. Cerebral blood flow changes in depressed patients after treatment with repetitive transcranial magnetic stimulation: evidence of individual variability. Neuropsychiatry Neuropsychol Behav Neurol 2002, 15(3):159-175.
230. Gershon A.A., Dannon P.N., Grunhaus L. Transcranial magnetic stimulation in the treatment of depression. Am J Psychiatr 2003, 160(5):835-845.
231. Pascual-Leone A., Rubio B., Pallardó F., et al. Rapid-rate transcranial magnetic stimulation of left dorsolateral prefrontal cortex in drug-resistant depression. Lancet 1996, 348(9022):233-237.
232. D'Agati D., Bloch Y., Levkovitz Y., et al. rTMS for adolescents: safety and efficacy considerations. Psychiatry Res 2010, 177(3):280-285.
233. Gavrilov L.R., Tsirulnikov E.M., Davies I.A. Application of focused ultrasound for the stimulation of neural structures. Ultrasound Med Biol 1996, 22(2):179-192.
234. Martin E., Jeanmonod D., Morel A., et al. High-intensity focused ultrasound for noninvasive functional neurosurgery. Ann Neurol 2009, 66(6):858-861.
235. Gunther M., Phillips K.D. Cranial electrotherapy stimulation for the treatment of depression. J Psychosoc Nurs Ment Health Serv 2010, 48(11):37-42.
236. Lefaucheur J.P. Principles of therapeutic use of transcranial and epidural cortical stimulation. Clin Neurophysiol 2008, 119(10):2179-2184.
237. Hung C.W., Liou Y.J., Lu S.W., et al. Stem cell-based neuroprotective and neurorestorative strategies. Int J Mol Sci 2010, 11(5):2039-2055.
238. Alexander B., Warner-Schmidt J., Eriksson T., et al. Reversal of depressed behaviors in mice by p11 gene therapy in the nucleus accumbens. Sci Transl Med 2010, 2(54):54ra76.
239. Fu C.H., Williams S.C., Cleare A.J., et al. Attenuation of the neural response to sad faces in major depression by antidepressant treatment: a prospective, event-related functional magnetic resonance imaging study. Arch Gen Psychiatry 2004, 61(9):877-889.