Central nervous system function in youth with type 1 diabetes 12 years after disease onset

Diabetes Care

Volumn 32, Issue 3, 2009, Pages 445-450

  Northam, Elisabeth A ^a,b   Rankins, Debbie ^b   Lin, Ashleigh ^b   Wellard, R Mark ^c,d   Pell, Gaby S ^d   Finch, Sue J ^a   Werther, George A ^e   Cameron, Fergus J ^e  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b MURDOCH CHILDREN'S RESEARCH INSTITUTE   (Australia)

^c QUEENSLAND UNIVERSITY OF TECHNOLOGY   (Australia)

^d AUSTIN HEALTH   (Australia)

^e ROYAL CHILDREN'S HOSPITAL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE; INOSITOL; N ACETYLASPARTIC ACID;

ADULT; ARTICLE; BASAL GANGLION; BRAIN FUNCTION; BRAIN SIZE; CAUDATE NUCLEUS; CENTRAL NERVOUS SYSTEM; COGNITION; CONTROLLED STUDY; DEMYELINATION; DIABETIC PATIENT; FEMALE; FRONTAL CORTEX; FRONTAL LOBE; GLIOSIS; GRAY MATTER; HUMAN; HYPOGLYCEMIA; INSULA; INSULIN DEPENDENT DIABETES MELLITUS; INTELLIGENCE QUOTIENT; MAJOR CLINICAL STUDY; MALE; METABOLIC REGULATION; NEUROIMAGING; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OSMOLARITY; PROSPECTIVE STUDY; RATING SCALE; SUBICULUM; TEMPORAL LOBE; THALAMUS; WECHSLER ABBREVIATED SCALE OF GENERAL INTELLIGENCE; WHITE MATTER;

ADOLESCENT; ADULT; AGE OF ONSET; BRAIN; CASE-CONTROL STUDIES; DIABETES MELLITUS, TYPE 1; FEMALE; HUMANS; INTELLIGENCE; INTELLIGENCE TESTS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; THALAMUS; TIME FACTORS; YOUNG ADULT;

EID: 64749088646     PISSN: 01495992     EISSN: 19355548     Source Type: Journal    
DOI: 10.2337/dc08-1657     Document Type: Article

References (25)

1. McCall A, Figlewicz D: How does diabetes mellitus produce brain dysfunction? Diabetes Spectrum 10:25-31, 1997
2. Musen G, Lyoo IK, Sparks CR, Weinger K, Hwang J, Ryan CM, Jimerson DC, Hennen J, Renshaw PF, Jacobson AM: Effects of type 1 diabetes on gray matter density as measured by voxel-based morphometry. Diabetes 55:326-333, 2006
3. Wessels AM, Simsek S, Remijnse PL, Veltman DJ, Biessels GJ, Barkhof F, Scheltens P, Snoek FJ, Heine RJ, Rombouts SA: Voxel-based morphometry demonstrates reduced grey matter density on brain MRI in patients with diabetic retinopathy. Diabetologia 49:2474-2480, 2006
4. Geissler A, Frund R, Scholmerich J, Feuerbach S, Zietz B: Alterations of cerebral metabolism in patients with diabetes mellitus studied by proton magnetic resonance spectroscopy. Exp Clin Endocrinol Diabetes 111:421-427, 2003
5. Makimattila S, Malmberg-Ceder K, Hakkinen AM, Vuori K, Salonen O, Summanen P, Yke-Jarvinen H, Kaste M, Heikkinen S, Lundbom N, Roine RO: Brain metabolic alterations in patients with type 1 diabetes-hyperglycemia-induced injury. J Cereb Blood Row Metab 24: 1393-1399, 2004
6. Brands AM, Biessels GJ, de Haan EH, Kappelle LJ, Kessels RP: The effects of type 1 diabetes on cognitive performance: a meta-analysis. Diabetes Care 28:726-735, 2005
7. Ryan C: Why is cognitive dysfunction associated with the development of diabetes early in life? The diathesis hypothesis. Pediatr Diabetes 7:289-297, 2006
8. Northam E, Rankins D, Cameron F: Therapy insight: the impact of type 1 diabetes on brain development and function. Nat Clin Pract Neurol 2:78-86, 2006
9. Perantie DC, Wu J, Roller JM, Lim A, Warren SL, Black KJ, Sadler M, White NH, Hershey T: Regional brain volume differences associated with hyperglycemia and severe hypoglycemia in youth with type 1 diabetes. Diabetes Care 30: 2331-2337,2007
10. Sarac K, Akinci A, Alkan A, Asian M, Baysal T, Ozcan C: Brain metabolite changes on proton magnetic resonance spectroscopy in children with poorly controlled type 1 diabetes. Neuroradiology 47:562-565, 2007
11. The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study Research Group: Long-term effect of diabetes and its treatment on cognitive function. N Engl J Med 356:1842-1852, 2007
12. Northam EA, Anderson PJ, Jacobs R, Hughes M, Warne G, Werther G: Neuro- psychological profiles of children with type 1 diabetes 6 years after disease onset. Diabetes Care 24:1541-1546, 2001
13. Wechsler D: Wechsler Abbreviated Scale of Intelligence Manual. The Psychological Corporation, San Antonio, TX, 1999
14. Provencher SW: Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 30: 672-679, 1993
15. Ashburner J, Friston KJ: Voxel-based morphometry-the methods. Neuroimage 11:805-821,2000
16. Pell GS, Briellmann RS, Waites AB, Abbott DF, Jackson GD: Voxel-based relaxometry: a new approach for analysis of T2 relaxometry changes in epilepsy. Neuro-image 21:707-713, 2004
17. Ross AJ, Sachdev PS: Magnetic resonance spectroscopy in cognitive research. Brain Res 44:83-102, 2004
18. Kantarci K, Petersen RC, Boeve BF, Knopman DS, Tang-Wai DF, O'Brien PC, Weigand SD, Edland SD, Smith GE, Ivnik RJ, Ferman TJ, Tangalos EG, Jack CR: MR spectroscopy in common dementias. Neurology 63:1393-1398, 2004
19. Malone JI, Hanna SK, Saporta S: Hyperglycemic brain injury in the rat. Brain Res 1076:9-15, 2006
20. Cameron FJ, Kean MJ, Wellard RM, Werther GA, Neils JJ, Inder TE: Insights into the acute metabolic changes associated with childhood diabetes. Diabet Med 22: 648-653, 2005
21. Muranyi M, Fujioka M, He Q, Han A, Yong G, Csiszar K, Li P: Diabetes activates cell death pathway after transient focal cerebral ischemia. Diabetes 52:481-486, 2003
22. Dreifuss S, Vingerhoets FJ, Lazeyras F, Andino SG, Spinelli L, Delavelle J, Seeck M: Volumetric measurements of subcortical nuclei in patients with temporal lobe epilepsy. Neurology 57:1636-1641, 2001
23. Briellmann RS, Jackson GD, Pell GS, Mitchell LA, Abbott DF: Structural abnormalities remote from the seizure focus: a study using T2 relaxometry at 3T. Neurology 62:2303-2308, 2004
24. Lenroot RK, Giedd JN: Brain development in children and adolescents: Insights from anatomical magnetic resonance imaging. Neurosci Biobehav Rev 30:718-729, 2006
25. Biessels GJ, Staekenborg S, Brunner E, Brayne C, Scheltens P: Risk of dementia in diabetes mellitus: a systematic review. Lancet Neurol 5:64-74, 2006