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Volumn 490, Issue 1-3, 2004, Pages 147-158

Cerebral glucose metabolism in diabetes mellitus

Author keywords

Cerebral glucose metabolism; Diabetes mellitus; Hypoglycemia

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; GLYCOGEN; INSULIN;

EID: 1842684425     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2004.02.052     Document Type: Article
Times cited : (114)

References (127)
  • 1
    • 0019852047 scopus 로고
    • Hypoglycemic brain injury: Phospholipids, free fatty acids, and cyclic nucleotides in the cerebellum of the rat after 30 and 60 minutes of severe insulin-induced hypoglycemia
    • Agardh C.D., Siesjö B.K. Hypoglycemic brain injury: phospholipids, free fatty acids, and cyclic nucleotides in the cerebellum of the rat after 30 and 60 minutes of severe insulin-induced hypoglycemia. J. Cereb. Blood Flow Metab. 1:1981;267-275.
    • (1981) J. Cereb. Blood Flow Metab. , vol.1 , pp. 267-275
    • Agardh, C.D.1    Siesjö, B.K.2
  • 2
    • 0018826967 scopus 로고
    • Severe hypoglycemia leads to accumulation of arachidonic acid in brain tissue
    • Agardh C.D., Westerberg E., Siesjo B.K. Severe hypoglycemia leads to accumulation of arachidonic acid in brain tissue. Acta Physiol. Scand. 109:1980;115-116.
    • (1980) Acta Physiol. Scand. , vol.109 , pp. 115-116
    • Agardh, C.D.1    Westerberg, E.2    Siesjo, B.K.3
  • 3
    • 0019831010 scopus 로고
    • Hypoglycemic brain injury: Metabolic and structural findings in rat cerebellar cortex during profound insulin-induced hypoglycemia and in the recovery period following glucose administration
    • Agardh C.D., Kalimo H., Olsson Y., Siesjö B.K. Hypoglycemic brain injury: metabolic and structural findings in rat cerebellar cortex during profound insulin-induced hypoglycemia and in the recovery period following glucose administration. J. Cereb. Blood Flow Metab. 1:1981;71-84.
    • (1981) J. Cereb. Blood Flow Metab. , vol.1 , pp. 71-84
    • Agardh, C.D.1    Kalimo, H.2    Olsson, Y.3    Siesjö, B.K.4
  • 4
    • 0022254299 scopus 로고
    • The temporal evolution of hypoglycemic brain damage: II. Light- and electron-microscopic findings in the hippocampal gyrus and subiculum of the rat
    • Auer R.N., Kalimo H., Olsson Y., Siesjö B.K. The temporal evolution of hypoglycemic brain damage: II. Light- and electron-microscopic findings in the hippocampal gyrus and subiculum of the rat. Acta Neuropathol. (Berl.). 67:1985;25-36.
    • (1985) Acta Neuropathol. (Berl.) , vol.67 , pp. 25-36
    • Auer, R.N.1    Kalimo, H.2    Olsson, Y.3    Siesjö, B.K.4
  • 5
    • 0022263019 scopus 로고
    • The temporal evolution of hypoglycemic brain damage: I. Light- and electron-microscopic findings in the rat cerebral cortex
    • Auer R.N., Kalimo H., Olsson Y., Siesjö B.K. The temporal evolution of hypoglycemic brain damage: I. Light- and electron-microscopic findings in the rat cerebral cortex. Acta Neuropathol. (Berl.). 67:1985;13-24.
    • (1985) Acta Neuropathol. (Berl.) , vol.67 , pp. 13-24
    • Auer, R.N.1    Kalimo, H.2    Olsson, Y.3    Siesjö, B.K.4
  • 6
    • 1842720976 scopus 로고
    • Cerebral metabolism and hypoglycaemia
    • V. Marks, & F.C. Rose. Oxford: Blackwell
    • Bachelard H. Cerebral metabolism and hypoglycaemia. Marks V., Rose F.C. Hypoglycaemia. 1981;51-68 Blackwell, Oxford.
    • (1981) Hypoglycaemia , pp. 51-68
    • Bachelard, H.1
  • 7
    • 0036895563 scopus 로고    scopus 로고
    • The role of insulin in human brain glucose metabolism: An 18fluoro-deoxyglucose positron emission tomography study
    • Bingham E.M., Hopkins D., Smith D., Pernet A., Hallett W., Reed L., Marsden P.K., Amiel S.A. The role of insulin in human brain glucose metabolism: an 18fluoro-deoxyglucose positron emission tomography study. Diabetes. 51(12):2002;3384-3390.
    • (2002) Diabetes , vol.51 , Issue.12 , pp. 3384-3390
    • Bingham, E.M.1    Hopkins, D.2    Smith, D.3    Pernet, A.4    Hallett, W.5    Reed, L.6    Marsden, P.K.7    Amiel, S.A.8
  • 8
    • 0035143089 scopus 로고    scopus 로고
    • Effects of short-term improvement of insulin treatment and glycemia on hepatic glycogen metabolism in type 1 diabetes
    • Bischof M.G., Krssak M., Krebs M., Bernroider E., Stingl H., Waldhausl W., Roden M. Effects of short-term improvement of insulin treatment and glycemia on hepatic glycogen metabolism in type 1 diabetes. Diabetes. 50(2):2001;392-398.
    • (2001) Diabetes , vol.50 , Issue.2 , pp. 392-398
    • Bischof, M.G.1    Krssak, M.2    Krebs, M.3    Bernroider, E.4    Stingl, H.5    Waldhausl, W.6    Roden, M.7
  • 10
    • 0033049682 scopus 로고    scopus 로고
    • Chronic hypoglycemia and diabetes impair counterregulation induced by localized 2-deoxy-glucose perfusion of the ventromedial hypothalamus in rats
    • Borg M.A., Borg W.P., Tamborlane W.V., Brines M.L., Shulman G.I., Sherwin R.S. Chronic hypoglycemia and diabetes impair counterregulation induced by localized 2-deoxy-glucose perfusion of the ventromedial hypothalamus in rats. Diabetes. 48(3):1999;584-587.
    • (1999) Diabetes , vol.48 , Issue.3 , pp. 584-587
    • Borg, M.A.1    Borg, W.P.2    Tamborlane, W.V.3    Brines, M.L.4    Shulman, G.I.5    Sherwin, R.S.6
  • 11
    • 0345700729 scopus 로고    scopus 로고
    • Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation
    • Borg M.A., Tamborlane W.V., Shulman G.I., Sherwin R.S. Local lactate perfusion of the ventromedial hypothalamus suppresses hypoglycemic counterregulation. Diabetes. 52(3):2003;663-666.
    • (2003) Diabetes , vol.52 , Issue.3 , pp. 663-666
    • Borg, M.A.1    Tamborlane, W.V.2    Shulman, G.I.3    Sherwin, R.S.4
  • 12
    • 0033777907 scopus 로고    scopus 로고
    • A quantitative analysis of L-glutamate-regulated Na+ dynamics in mouse cortical astrocytes: Implications for cellular bioenergetics
    • Chatton J.Y., Marquet P., Magistretti P.J. A quantitative analysis of L-glutamate-regulated Na+ dynamics in mouse cortical astrocytes: implications for cellular bioenergetics. Eur. J. Neurosci. 12(11):2000;3843-3853.
    • (2000) Eur. J. Neurosci. , vol.12 , Issue.11 , pp. 3843-3853
    • Chatton, J.Y.1    Marquet, P.2    Magistretti, P.J.3
  • 13
    • 0142027742 scopus 로고    scopus 로고
    • GABA uptake into astrocytes is not associated with significant metabolic cost: Implications for brain imaging of inhibitory transmission
    • Chatton J.Y., Pellerin L., Magistretti P.J. GABA uptake into astrocytes is not associated with significant metabolic cost: implications for brain imaging of inhibitory transmission. Proc. Natl. Acad. Sci. U. S. A. 100(21):2003;12456-12461.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , Issue.21 , pp. 12456-12461
    • Chatton, J.Y.1    Pellerin, L.2    Magistretti, P.J.3
  • 15
    • 0242574396 scopus 로고    scopus 로고
    • Energy substrates for neurons during neural activity: A critical review of the astrocyte-neuron lactate shuttle hypothesis
    • Chih C.P., Roberts E.L. Jr. Energy substrates for neurons during neural activity: a critical review of the astrocyte-neuron lactate shuttle hypothesis. J. Cereb. Blood Flow Metab. 23(11):2003;1263-1281.
    • (2003) J. Cereb. Blood Flow Metab. , vol.23 , Issue.11 , pp. 1263-1281
    • Chih, C.P.1    Roberts Jr., E.L.2
  • 16
    • 0012641870 scopus 로고    scopus 로고
    • 13C NMR assessment of brain glycogen concentration and turnover in the awake rat
    • 13C NMR assessment of brain glycogen concentration and turnover in the awake rat. Neurochem. Int. 43.4-43.5:2003;317-322.
    • (2003) Neurochem. Int. , vol.434-435 , pp. 317-322
    • Choi, I.Y.1    Gruetter, R.2
  • 17
    • 0344850193 scopus 로고    scopus 로고
    • Noninvasive measurements of [1-(13)C]glycogen concentrations and metabolism in rat brain in vivo
    • Choi I.Y., Tkac I., Ugurbil K., Gruetter R. Noninvasive measurements of [1-(13)C]glycogen concentrations and metabolism in rat brain in vivo. J. Neurochem. 73.3:1999;1300-1308.
    • (1999) J. Neurochem. , vol.733 , pp. 1300-1308
    • Choi, I.Y.1    Tkac, I.2    Ugurbil, K.3    Gruetter, R.4
  • 18
    • 0034981078 scopus 로고    scopus 로고
    • In vivo measurements of brain glucose transport using the reversible Michaelis-Menten model and simultaneous measurements of cerebral blood flow changes during hypoglycemia
    • Choi I.Y., Lee S.P., Kim S.G., Gruetter R. In vivo measurements of brain glucose transport using the reversible Michaelis-Menten model and simultaneous measurements of cerebral blood flow changes during hypoglycemia. J. Cereb. Blood Flow Metab. 21(6):2001;653-663.
    • (2001) J. Cereb. Blood Flow Metab. , vol.21 , Issue.6 , pp. 653-663
    • Choi, I.Y.1    Lee, S.P.2    Kim, S.G.3    Gruetter, R.4
  • 19
    • 0345074150 scopus 로고    scopus 로고
    • Effect of hypoglycemia on brain glycogen metabolism in vivo
    • Choi I.Y., Seaquist E.R., Gruetter R. Effect of hypoglycemia on brain glycogen metabolism in vivo. J. Neurosci. Res. 72(1):2003;25-32.
    • (2003) J. Neurosci. Res. , vol.72 , Issue.1 , pp. 25-32
    • Choi, I.Y.1    Seaquist, E.R.2    Gruetter, R.3
  • 20
    • 0000202516 scopus 로고    scopus 로고
    • Circulation and energy metabolism of the brain
    • G.J. Siegel, B.W. Agranoff, R.W. Albers, S.K. Molinoff, P.B. Fisher, & M.D. Uhler. Philadelphia: Lippincott-Raven
    • Clarke D.D., Sokoloff L. Circulation and energy metabolism of the brain. Siegel G.J., Agranoff B.W., Albers R.W., Molinoff S.K., Fisher P.B., Uhler M.D. Basic neurochemistry. 1999;637-669 Lippincott-Raven, Philadelphia.
    • (1999) Basic Neurochemistry , pp. 637-669
    • Clarke, D.D.1    Sokoloff, L.2
  • 21
    • 0036021728 scopus 로고    scopus 로고
    • The effects of glucose fluctuation on cognitive function and QOL: The functional costs of hypoglycaemia and hyperglycaemia among adults with type 1 or type 2 diabetes
    • Cox D., Gonder-Frederick L., McCall A., Kovatchev B., Clarke W. The effects of glucose fluctuation on cognitive function and QOL: the functional costs of hypoglycaemia and hyperglycaemia among adults with type 1 or type 2 diabetes. Int. J. Clin. Pract. (Suppl. 129):2002;20-26.
    • (2002) Int. J. Clin. Pract. , vol.129 , Issue.SUPPL. , pp. 20-26
    • Cox, D.1    Gonder-Frederick, L.2    McCall, A.3    Kovatchev, B.4    Clarke, W.5
  • 22
    • 0016198692 scopus 로고
    • The estimation of rates of utilization of glucose and ketone bodies in the brain of the suckling rat using compartmental analysis of isotopic data
    • Cremer J.E., Heath D.F. The estimation of rates of utilization of glucose and ketone bodies in the brain of the suckling rat using compartmental analysis of isotopic data. Biochem. J. 142:1974;527-544.
    • (1974) Biochem. J. , vol.142 , pp. 527-544
    • Cremer, J.E.1    Heath, D.F.2
  • 24
    • 0036898698 scopus 로고    scopus 로고
    • High glycogen levels in brains of rats with minimal environmental stimuli: Implications for metabolic contributions of working astrocytes
    • Cruz N.F., Dienel G.A. High glycogen levels in brains of rats with minimal environmental stimuli: implications for metabolic contributions of working astrocytes. J. Cereb. Blood Flow Metab. 22(12):2002;1476-1489.
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , Issue.12 , pp. 1476-1489
    • Cruz, N.F.1    Dienel, G.A.2
  • 25
    • 0036020278 scopus 로고    scopus 로고
    • Hypoglycaemia: The limiting factor in the glycaemic management of type I and type II diabetes
    • Cryer P.E. Hypoglycaemia: the limiting factor in the glycaemic management of type I and type II diabetes. Diabetologia. 45(7):2002;937-948.
    • (2002) Diabetologia , vol.45 , Issue.7 , pp. 937-948
    • Cryer, P.E.1
  • 27
    • 0001790785 scopus 로고
    • Effects of hypoglycaemia on cognitive function
    • B. Frier, & M. Fisher. London: Edward Arnold
    • Deary I.J. Effects of hypoglycaemia on cognitive function. Frier B., Fisher M. Hypoglycaemia and Diabetes: Clinical and Physiological Aspects. 1993;80-92 Edward Arnold, London.
    • (1993) Hypoglycaemia and Diabetes: Clinical and Physiological Aspects , pp. 80-92
    • Deary, I.J.1
  • 28
    • 0037963512 scopus 로고    scopus 로고
    • Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures
    • Debernardi R., Pierre K., Lengacher S., Magistretti P.J., Pellerin L. Cell-specific expression pattern of monocarboxylate transporters in astrocytes and neurons observed in different mouse brain cortical cell cultures. J. Neurosci. Res. 73(2):2003;141-155.
    • (2003) J. Neurosci. Res. , vol.73 , Issue.2 , pp. 141-155
    • Debernardi, R.1    Pierre, K.2    Lengacher, S.3    Magistretti, P.J.4    Pellerin, L.5
  • 29
    • 0037727912 scopus 로고    scopus 로고
    • Neighborly interactions of metabolically-activated astrocytes in vivo
    • Dienel G.A., Cruz N.F. Neighborly interactions of metabolically-activated astrocytes in vivo. Neurochem. Int. 43(4-5):2003;339-354.
    • (2003) Neurochem. Int. , vol.43 , Issue.45 , pp. 339-354
    • Dienel, G.A.1    Cruz, N.F.2
  • 30
    • 0036897552 scopus 로고    scopus 로고
    • Generalized sensory stimulation of conscious rats increases labeling of oxidative pathways of glucose metabolism when the brain glucose-oxygen uptake ratio rises
    • Dienel G.A., Wang R.Y., Cruz N.F. Generalized sensory stimulation of conscious rats increases labeling of oxidative pathways of glucose metabolism when the brain glucose-oxygen uptake ratio rises. J. Cereb. Blood Flow Metab. 22(12):2002;1490-1502.
    • (2002) J. Cereb. Blood Flow Metab. , vol.22 , Issue.12 , pp. 1490-1502
    • Dienel, G.A.1    Wang, R.Y.2    Cruz, N.F.3
  • 31
    • 0028817548 scopus 로고
    • Cognitive function in patients with insulin-dependent diabetes mellitus during hyperglycemia and hypoglycemia
    • Draelos M.T., Jacobson A.M., Weinger K., Widom B., Ryan C.M., Finkelstein D.M., Simonson D.C. Cognitive function in patients with insulin-dependent diabetes mellitus during hyperglycemia and hypoglycemia. Am. J. Med. 98(2):1995;135-144.
    • (1995) Am. J. Med. , vol.98 , Issue.2 , pp. 135-144
    • Draelos, M.T.1    Jacobson, A.M.2    Weinger, K.3    Widom, B.4    Ryan, C.M.5    Finkelstein, D.M.6    Simonson, D.C.7
  • 32
    • 0023118941 scopus 로고
    • Regional cerebral blood flow decreases during chronic and acute hyperglycemia
    • Duckrow R.B., Beard D.C., Brennan R.W. Regional cerebral blood flow decreases during chronic and acute hyperglycemia. Stroke. 18:1987;52-58.
    • (1987) Stroke , vol.18 , pp. 52-58
    • Duckrow, R.B.1    Beard, D.C.2    Brennan, R.W.3
  • 33
    • 0037707488 scopus 로고    scopus 로고
    • Energy contribution of octanoate to intact rat brain metabolism measured by 13C nuclear magnetic resonance spectroscopy
    • Ebert D., Haller R.G., Walton M.E. Energy contribution of octanoate to intact rat brain metabolism measured by 13C nuclear magnetic resonance spectroscopy. J. Neurosci. 23:2003;5928-5935.
    • (2003) J. Neurosci. , vol.23 , pp. 5928-5935
    • Ebert, D.1    Haller, R.G.2    Walton, M.E.3
  • 34
    • 0031658958 scopus 로고    scopus 로고
    • Blood-to-brain glucose transport and cerebral glucose metabolism are not reduced in poorly controlled type 1 diabetes
    • Fanelli C.G., Dence C.S., Markham J., Videen T.O., Paramore D.S., Cryer P.E., Powers W.J. Blood-to-brain glucose transport and cerebral glucose metabolism are not reduced in poorly controlled type 1 diabetes. Diabetes. 47:1998;1444-1450.
    • (1998) Diabetes , vol.47 , pp. 1444-1450
    • Fanelli, C.G.1    Dence, C.S.2    Markham, J.3    Videen, T.O.4    Paramore, D.S.5    Cryer, P.E.6    Powers, W.J.7
  • 35
    • 0030583628 scopus 로고    scopus 로고
    • Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: A molecular study
    • Figlewicz D.P., Brot M.D., McCall A.L., Szot P. Diabetes causes differential changes in CNS noradrenergic and dopaminergic neurons in the rat: a molecular study. Brain Res. 736(1-2):1996;54-60.
    • (1996) Brain Res. , vol.736 , Issue.12 , pp. 54-60
    • Figlewicz, D.P.1    Brot, M.D.2    McCall, A.L.3    Szot, P.4
  • 36
    • 0012987101 scopus 로고
    • The blood sugar following insulin administration and the symptom complex-hypoglycaemia
    • Fletcher A.A., Campbell W.R. The blood sugar following insulin administration and the symptom complex-hypoglycaemia. J. Metab. Res. (2):1922;637-649.
    • (1922) J. Metab. Res. , Issue.2 , pp. 637-649
    • Fletcher, A.A.1    Campbell, W.R.2
  • 37
    • 0342963103 scopus 로고
    • Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects
    • Fox P.T., Raichle M.E. Focal physiological uncoupling of cerebral blood flow and oxidative metabolism during somatosensory stimulation in human subjects. Proc. Natl. Acad. Sci. U. S. A. 83(4):1986;1140-1144.
    • (1986) Proc. Natl. Acad. Sci. U. S. A. , vol.83 , Issue.4 , pp. 1140-1144
    • Fox, P.T.1    Raichle, M.E.2
  • 38
    • 0023780085 scopus 로고
    • Nonoxidative glucose consumption during focal physiologic neural activity
    • Fox P.T., Raichle M.E., Mintun M.A., Dence C. Nonoxidative glucose consumption during focal physiologic neural activity. Science. 241(4864):1988;462-464.
    • (1988) Science , vol.241 , Issue.4864 , pp. 462-464
    • Fox, P.T.1    Raichle, M.E.2    Mintun, M.A.3    Dence, C.4
  • 39
    • 0019787087 scopus 로고
    • Blood-brain glucose transfer: Repression in chronic hyperglycemia
    • Gjedde A., Crone C. Blood-brain glucose transfer: repression in chronic hyperglycemia. Science. 214:1981;456-457.
    • (1981) Science , vol.214 , pp. 456-457
    • Gjedde, A.1    Crone, C.2
  • 40
    • 0029162104 scopus 로고
    • Hypoglycemia-induced cognitive dysfunction in diabetes mellitus: Effect of hypoglycemia unawareness
    • Gold A.E., MacLeod K.M., Deary I.J., Frier B.M. Hypoglycemia-induced cognitive dysfunction in diabetes mellitus: effect of hypoglycemia unawareness. Physiol. Behav. 58(3):1995;501-511.
    • (1995) Physiol. Behav. , vol.58 , Issue.3 , pp. 501-511
    • Gold, A.E.1    MacLeod, K.M.2    Deary, I.J.3    Frier, B.M.4
  • 41
    • 0002805456 scopus 로고    scopus 로고
    • The emotional, social, and behavioral implications of insulin-induced hypoglycemia
    • Gonder-Frederick L.A., Clarke W.L., Cox D.J. The emotional, social, and behavioral implications of insulin-induced hypoglycemia. Semin. Clin. Neuropsychiatry. 2(1):1997;57-65.
    • (1997) Semin. Clin. Neuropsychiatry , vol.2 , Issue.1 , pp. 57-65
    • Gonder-Frederick, L.A.1    Clarke, W.L.2    Cox, D.J.3
  • 43
    • 0035999512 scopus 로고    scopus 로고
    • 13C NMR studies of compartmentalized cerebral carbohydrate metabolism
    • 13C NMR studies of compartmentalized cerebral carbohydrate metabolism. Neurochem. Int. 41.2-41.3:2002;143-154.
    • (2002) Neurochem. Int. , vol.412-413 , pp. 143-154
    • Gruetter, R.1
  • 44
    • 0141481875 scopus 로고    scopus 로고
    • Glycogen: The forgotten cerebral energy store
    • Gruetter R. Glycogen: the forgotten cerebral energy store. J. Neurosci. Res. 74(2):2003;179-183.
    • (2003) J. Neurosci. Res. , vol.74 , Issue.2 , pp. 179-183
    • Gruetter, R.1
  • 45
    • 0021166411 scopus 로고
    • Cerebral extracellular calcium activity in severe hypoglycemia: Relation to extracellular potassium and energy state
    • Harris R.J., Wieloch T., Symon L., Siesjö B.K. Cerebral extracellular calcium activity in severe hypoglycemia: relation to extracellular potassium and energy state. J. Cereb. Blood Flow Metab. 4:1984;187-193.
    • (1984) J. Cereb. Blood Flow Metab. , vol.4 , pp. 187-193
    • Harris, R.J.1    Wieloch, T.2    Symon, L.3    Siesjö, B.K.4
  • 46
    • 0018751594 scopus 로고
    • Ketone bodies are selectively used by individual brain regions
    • Hawkins R.A., Biebuyck J.F. Ketone bodies are selectively used by individual brain regions. Science. 205:1979;325-327.
    • (1979) Science , vol.205 , pp. 325-327
    • Hawkins, R.A.1    Biebuyck, J.F.2
  • 47
    • 0023252127 scopus 로고
    • Glucose and fatty acid metabolism in normal and diabetic rabbit cerebral microvessels
    • Hingorani V., Brecher P. Glucose and fatty acid metabolism in normal and diabetic rabbit cerebral microvessels. Am. J. Physiol. 252:1987;E648-E653.
    • (1987) Am. J. Physiol. , vol.252
    • Hingorani, V.1    Brecher, P.2
  • 48
    • 0020691399 scopus 로고
    • A survey of cognitive functioning at difference glucose levels in diabetic persons
    • Holmes C.S., Hayford J.T., Gonzalez J.L., Weydert J.A. A survey of cognitive functioning at difference glucose levels in diabetic persons. Diab. Care. 6:1983;180-185.
    • (1983) Diab. Care , vol.6 , pp. 180-185
    • Holmes, C.S.1    Hayford, J.T.2    Gonzalez, J.L.3    Weydert, J.A.4
  • 49
    • 0036788292 scopus 로고    scopus 로고
    • AICAR Administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats
    • Iglesias M.A., Ye J.M., Frangioudakis G., Saha A.K., Tomas E., Ruderman N.B., Cooney G.J., Kraegen E.W. AICAR Administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats. Diabetes. 51(10):2002;2886-2894.
    • (2002) Diabetes , vol.51 , Issue.10 , pp. 2886-2894
    • Iglesias, M.A.1    Ye, J.M.2    Frangioudakis, G.3    Saha, A.K.4    Tomas, E.5    Ruderman, N.B.6    Cooney, G.J.7    Kraegen, E.W.8
  • 50
    • 0025363792 scopus 로고
    • Regional brain glucose metabolism and blood flow in streptozocin-induced diabetic rats
    • Jakobsen J., Nedergaard M., Aarslew-Jensen M., Diemer N.H. Regional brain glucose metabolism and blood flow in streptozocin-induced diabetic rats. Diabetes. 39:1990;437-440.
    • (1990) Diabetes , vol.39 , pp. 437-440
    • Jakobsen, J.1    Nedergaard, M.2    Aarslew-Jensen, M.3    Diemer, N.H.4
  • 51
    • 0020027766 scopus 로고
    • Thickened cerebral cortical capillary basement membranes in diabetics
    • Johnson P.C., Brendel K., Meezan E. Thickened cerebral cortical capillary basement membranes in diabetics. Arch. Pathol. Lab. Med. 106:1982;214-217.
    • (1982) Arch. Pathol. Lab. Med. , vol.106 , pp. 214-217
    • Johnson, P.C.1    Brendel, K.2    Meezan, E.3
  • 53
    • 0035685698 scopus 로고    scopus 로고
    • The extended GLUT-family of sugar/polyol transport facilitators: Nomenclature, sequence characteristics, and potential function of its novel members (review)
    • Joost H.G., Thorens B. The extended GLUT-family of sugar/polyol transport facilitators: nomenclature, sequence characteristics, and potential function of its novel members (review). Mol. Membr. Biol. 18(4):2001;247-256.
    • (2001) Mol. Membr. Biol. , vol.18 , Issue.4 , pp. 247-256
    • Joost, H.G.1    Thorens, B.2
  • 54
    • 0022261630 scopus 로고
    • The temporal evolution of hypoglycemic brain damage: III. Light and electron microscopic findings in the rat caudoputamen
    • Kalimo H., Auer R.N., Siesjö B.K. The temporal evolution of hypoglycemic brain damage: III. Light and electron microscopic findings in the rat caudoputamen. Acta Neuropathol. (Berl.). 67:1985;37-50.
    • (1985) Acta Neuropathol. (Berl.) , vol.67 , pp. 37-50
    • Kalimo, H.1    Auer, R.N.2    Siesjö, B.K.3
  • 55
    • 0022969829 scopus 로고
    • Impaired autoregulation of cerebral blood flow in long-term type I (insulin-dependent) diabetic patients with nephropathy and retinopathy
    • Kastrup J., Rrsgaard S., Parving H.H., Lassen N.A. Impaired autoregulation of cerebral blood flow in long-term type I (insulin-dependent) diabetic patients with nephropathy and retinopathy. Clin. Physiol. 6:1986;549-559.
    • (1986) Clin. Physiol. , vol.6 , pp. 549-559
    • Kastrup, J.1    Rrsgaard, S.2    Parving, H.H.3    Lassen, N.A.4
  • 56
    • 0025036203 scopus 로고
    • Intravenous lidocaine and cerebral blood flow: Impaired microvascular reactivity in diabetic patients
    • Kastrup J., Petersen P., Dejgard A. Intravenous lidocaine and cerebral blood flow: impaired microvascular reactivity in diabetic patients. J. Clin. Pharmacol. 30:1990;318-323.
    • (1990) J. Clin. Pharmacol. , vol.30 , pp. 318-323
    • Kastrup, J.1    Petersen, P.2    Dejgard, A.3
  • 57
    • 0032914534 scopus 로고    scopus 로고
    • Neurocognitive functioning in children diagnosed with diabetes before age 10 years
    • Kaufman F.R., Epport K., Engilman R., Halvorson M. Neurocognitive functioning in children diagnosed with diabetes before age 10 years. J. Diabetes Its Complicat. 13(1):1999;31-38.
    • (1999) J. Diabetes Its Complicat. , vol.13 , Issue.1 , pp. 31-38
    • Kaufman, F.R.1    Epport, K.2    Engilman, R.3    Halvorson, M.4
  • 58
    • 0000005104 scopus 로고
    • Blood flow and oxygen consumption of the human brain in diabetic acidosis and coma
    • Kety S.S., Polis B.D., Nadler C.S., Schmidt C.F. Blood flow and oxygen consumption of the human brain in diabetic acidosis and coma. J. Clin. Invest. 27:1948;500-510.
    • (1948) J. Clin. Invest. , vol.27 , pp. 500-510
    • Kety, S.S.1    Polis, B.D.2    Nadler, C.S.3    Schmidt, C.F.4
  • 59
    • 84925030894 scopus 로고
    • Cerebral blood flow and metabolism in schizophrenia. The effects of barbiturate semi-narcosis, insulin coma, and electroshock
    • Kety S.S., Woodford R.B., Harmel M.H., Freyhan F.A., Appel K.E., Schmidt C.F. Cerebral blood flow and metabolism in schizophrenia. The effects of barbiturate semi-narcosis, insulin coma, and electroshock. Am. J. Psychiatry. 104:1948;765-770.
    • (1948) Am. J. Psychiatry , vol.104 , pp. 765-770
    • Kety, S.S.1    Woodford, R.B.2    Harmel, M.H.3    Freyhan, F.A.4    Appel, K.E.5    Schmidt, C.F.6
  • 61
    • 0036662943 scopus 로고    scopus 로고
    • Brain glycogen decreases with increased periods of wakefulness: Implications for homeostatic drive to sleep
    • Kong J., Shepel P.N., Holden C.P., Mackiewicz M., Pack A.I., Geiger J.D. Brain glycogen decreases with increased periods of wakefulness: implications for homeostatic drive to sleep. J. Neurosci. 22(13):2002;5581-5587.
    • (2002) J. Neurosci. , vol.22 , Issue.13 , pp. 5581-5587
    • Kong, J.1    Shepel, P.N.2    Holden, C.P.3    MacKiewicz, M.4    Pack, A.I.5    Geiger, J.D.6
  • 62
    • 1842720977 scopus 로고    scopus 로고
    • Do people with T1DM recognize hyperglycemia?
    • (Abstract #1643)
    • Kovatchev B., Cox D., Summeers K. Do people with T1DM recognize hyperglycemia? Diabetes. 50(Suppl. 2):2001;. (Abstract #1643).
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 2
    • Kovatchev, B.1    Cox, D.2    Summeers, K.3
  • 63
    • 0024349850 scopus 로고
    • Impaired beta-adrenergic mediated cerebral blood flow response in streptozotocin diabetic rats
    • Lass P., Knudsen G.M., Pedersen E.V., Barry D.I. Impaired beta-adrenergic mediated cerebral blood flow response in streptozotocin diabetic rats. Pharmacol. Toxicol. 65:1989;318-320.
    • (1989) Pharmacol. Toxicol. , vol.65 , pp. 318-320
    • Lass, P.1    Knudsen, G.M.2    Pedersen, E.V.3    Barry, D.I.4
  • 66
    • 0032525884 scopus 로고    scopus 로고
    • Specific inhibition of GLUT2 in arcuate nucleus by antisense oligonucleotides suppresses nervous control of insulin secretion
    • Leloup C., Orosco M., Serradas P., Nicolaidis S., Penicaud L. Specific inhibition of GLUT2 in arcuate nucleus by antisense oligonucleotides suppresses nervous control of insulin secretion. Brain Res. Mol. Brain Res. 57(2):1998;275-280.
    • (1998) Brain Res. Mol. Brain Res. , vol.57 , Issue.2 , pp. 275-280
    • Leloup, C.1    Orosco, M.2    Serradas, P.3    Nicolaidis, S.4    Penicaud, L.5
  • 67
    • 0016116659 scopus 로고
    • Changes in carbohydrate substrates, amino acids and ammonia in the brain during insulin-induced hypoglycemia
    • Lewis L.D., Ljunggren B., Norberg K., Siesjö B.K. Changes in carbohydrate substrates, amino acids and ammonia in the brain during insulin-induced hypoglycemia. J. Neurochem. 23:1974;659-671.
    • (1974) J. Neurochem. , vol.23 , pp. 659-671
    • Lewis, L.D.1    Ljunggren, B.2    Norberg, K.3    Siesjö, B.K.4
  • 69
    • 0026683654 scopus 로고
    • The impact of diabetes on the CNS
    • McCall A.L. The impact of diabetes on the CNS. Diabetes. 41.5:1992;557-570.
    • (1992) Diabetes , vol.415 , pp. 557-570
    • McCall, A.L.1
  • 71
    • 0031204959 scopus 로고    scopus 로고
    • IDDM, counterregulation, and the brain
    • McCall A.L. IDDM, counterregulation, and the brain. Diabetes Care. 20.8:1997;1228-1230.
    • (1997) Diabetes Care , vol.208 , pp. 1228-1230
    • McCall, A.L.1
  • 72
    • 0031776183 scopus 로고    scopus 로고
    • New findings and treatment strategies for hypoglycemia and hypoglycemia unawareness
    • McCall A.L. New findings and treatment strategies for hypoglycemia and hypoglycemia unawareness. Curr. Opin. Endocrinol. Diabetes. 5:1998;136-143.
    • (1998) Curr. Opin. Endocrinol. Diabetes , vol.5 , pp. 136-143
    • McCall, A.L.1
  • 73
    • 0036369932 scopus 로고    scopus 로고
    • Diabetes mellitus and the central nervous system
    • McCall A.L. Diabetes mellitus and the central nervous system. Int. Rev. Neurobiol. 51:2002;415-453.
    • (2002) Int. Rev. Neurobiol. , vol.51 , pp. 415-453
    • McCall, A.L.1
  • 74
    • 0007392926 scopus 로고    scopus 로고
    • How does diabetes mellitus produce brain dysfunction?
    • McCall A.L., Figlewicz D.P. How does diabetes mellitus produce brain dysfunction? Diabetes Spectr. 10(1):1997;25-32.
    • (1997) Diabetes Spectr. , vol.10 , Issue.1 , pp. 25-32
    • McCall, A.L.1    Figlewicz, D.P.2
  • 75
    • 0012728882 scopus 로고
    • Metabolic fuel and amino acid transport into the brain in experimental diabetes mellitus
    • McCall A.L., Millington W.R., Wurtman R.J. Metabolic fuel and amino acid transport into the brain in experimental diabetes mellitus. Proc. Natl. Acad. Sci. U.S.A. 79:1982;5406-5410.
    • (1982) Proc. Natl. Acad. Sci. U.S.A. , vol.79 , pp. 5406-5410
    • McCall, A.L.1    Millington, W.R.2    Wurtman, R.J.3
  • 76
    • 0021507059 scopus 로고
    • Diabetes-induced alterations of glucose metabolism in rat cerebral microvessels
    • (End. Metab. 10)
    • McCall A.L., Gould J.B., Ruderman N.B. Diabetes-induced alterations of glucose metabolism in rat cerebral microvessels. Am. J. Physiol. 247:1984;E462-E467. (End. Metab. 10).
    • (1984) Am. J. Physiol. , vol.247
    • McCall, A.L.1    Gould, J.B.2    Ruderman, N.B.3
  • 78
    • 0023883412 scopus 로고
    • Effects of hypoglycemia and diabetes on fuel metabolism by rat brain microvessels
    • (End. Metab. 17)
    • McCall A.L., Sussman I., Tornheim K., Cordero R., Ruderman N.B. Effects of hypoglycemia and diabetes on fuel metabolism by rat brain microvessels. Am. J. Physiol. 254:1988;E272-E278. (End. Metab. 17).
    • (1988) Am. J. Physiol. , vol.254
    • McCall, A.L.1    Sussman, I.2    Tornheim, K.3    Cordero, R.4    Ruderman, N.B.5
  • 79
    • 0031023398 scopus 로고    scopus 로고
    • Forebrain endothelium expresses GLUT4, the insulin-responsive glucose transporter
    • McCall A.L., Van Bueren A.M., Huang L., Stenbit A., Celnik E., Charron M.J. Forebrain endothelium expresses GLUT4, the insulin-responsive glucose transporter. Brain Res. 744(2):1997;318-326.
    • (1997) Brain Res. , vol.744 , Issue.2 , pp. 318-326
    • McCall, A.L.1    Van Bueren, A.M.2    Huang, L.3    Stenbit, A.4    Celnik, E.5    Charron, M.J.6
  • 82
    • 0024066763 scopus 로고
    • Diabetes and the central nervous system
    • Mooradian A.D. Diabetes and the central nervous system. Endo. Rev. 9(3):1988;346-356.
    • (1988) Endo. Rev. , vol.9 , Issue.3 , pp. 346-356
    • Mooradian, A.D.1
  • 83
    • 0030890905 scopus 로고    scopus 로고
    • Central nervous system complications of diabetes mellitus - A perspective from the blood-brain barrier
    • Mooradian A.D. Central nervous system complications of diabetes mellitus - a perspective from the blood-brain barrier. Brain Res. Rev. 23(3):1997;210-218.
    • (1997) Brain Res. Rev. , vol.23 , Issue.3 , pp. 210-218
    • Mooradian, A.D.1
  • 84
    • 0026747016 scopus 로고
    • Beta-adrenergic receptor activity of cerebral microvessels in experimental diabetes mellitus
    • Mooradian A.D., Scarpace P.J. Beta-adrenergic receptor activity of cerebral microvessels in experimental diabetes mellitus. Brain Res. 583((1-2)):1992;155-160.
    • (1992) Brain Res. , vol.583 , Issue.1-2 , pp. 155-160
    • Mooradian, A.D.1    Scarpace, P.J.2
  • 85
    • 0026462612 scopus 로고
    • The effect of experimentally induced diabetes mellitus on the lipid order and composition of rat cerebral microvessels
    • Mooradian A.D., Smith T.L. The effect of experimentally induced diabetes mellitus on the lipid order and composition of rat cerebral microvessels. Neurosci. Lett. 145(2):1992;145-148.
    • (1992) Neurosci. Lett. , vol.145 , Issue.2 , pp. 145-148
    • Mooradian, A.D.1    Smith, T.L.2
  • 86
    • 0028170399 scopus 로고
    • Adenosine triphosphatases of rat cerebral microvessels. Effect of age and diabetes mellitus
    • Mooradian A.D., Grabau G., Bastani B. Adenosine triphosphatases of rat cerebral microvessels. Effect of age and diabetes mellitus. Life Sci. 55.16:1994;1261-1265.
    • (1994) Life Sci. , vol.5516 , pp. 1261-1265
    • Mooradian, A.D.1    Grabau, G.2    Bastani, B.3
  • 87
    • 0027955018 scopus 로고
    • Diabetes-related changes in the protein composition of rat cerebral microvessels
    • Mooradian A.D., Pinnas J.L., Lung C.C., Yahya M.D., Meredith K. Diabetes-related changes in the protein composition of rat cerebral microvessels. Neurochem. Res. 19(2):1994;123-128.
    • (1994) Neurochem. Res. , vol.19 , Issue.2 , pp. 123-128
    • Mooradian, A.D.1    Pinnas, J.L.2    Lung, C.C.3    Yahya, M.D.4    Meredith, K.5
  • 88
    • 0018897183 scopus 로고
    • Cerebral lesions in rats with streptozotocin-induced diabetes
    • Mukai N., Hori S., Pomeroy M. Cerebral lesions in rats with streptozotocin-induced diabetes. Acta Neuropathol. (Berl.). 51:1980;79-84.
    • (1980) Acta Neuropathol. (Berl.) , vol.51 , pp. 79-84
    • Mukai, N.1    Hori, S.2    Pomeroy, M.3
  • 89
    • 0023223807 scopus 로고
    • Cerebral blood flow increases during insulin-induced hypoglycaemia in type 1 (insulin-dependent) diabetic patients and control subjects
    • Neil H.A., Gale E.A., Hamilton S.J., Lopez Espinoza I., Kaura R., McCarthy S.T. Cerebral blood flow increases during insulin-induced hypoglycaemia in type 1 (insulin-dependent) diabetic patients and control subjects. Diabetologia. 30:1987;305-309.
    • (1987) Diabetologia , vol.30 , pp. 305-309
    • Neil, H.A.1    Gale, E.A.2    Hamilton, S.J.3    Lopez Espinoza, I.4    Kaura, R.5    McCarthy, S.T.6
  • 90
    • 0035805090 scopus 로고    scopus 로고
    • Co-localization of GLUT1 and GLUT4 in the blood-brain barrier of the rat ventromedial hypothalamus
    • Ngarmukos C., Baur E.L., Kumagai A.K. Co-localization of GLUT1 and GLUT4 in the blood-brain barrier of the rat ventromedial hypothalamus. Brain Res. 900(1):2001;1-8.
    • (2001) Brain Res. , vol.900 , Issue.1 , pp. 1-8
    • Ngarmukos, C.1    Baur, E.L.2    Kumagai, A.K.3
  • 91
    • 0037288941 scopus 로고    scopus 로고
    • Insulin and leptin revisited: Adiposity signals with overlapping physiological and intracellular signaling capabilities
    • Niswender K.D., Schwartz M.W. Insulin and leptin revisited: adiposity signals with overlapping physiological and intracellular signaling capabilities. Front. Neuroendocrinol. 24(1):2003;1-10.
    • (2003) Front. Neuroendocrinol. , vol.24 , Issue.1 , pp. 1-10
    • Niswender, K.D.1    Schwartz, M.W.2
  • 92
    • 0037315042 scopus 로고    scopus 로고
    • Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key mediator of insulin-induced anorexia
    • Niswender K.D., Morrison C.D., Clegg D.J., Olson R., Baskin D.G., Myers M.G. Jr., Seeley R.J., Schwartz M.W. Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia. Diabetes. 52(2):2003;227-231.
    • (2003) Diabetes , vol.52 , Issue.2 , pp. 227-231
    • Niswender, K.D.1    Morrison, C.D.2    Clegg, D.J.3    Olson, R.4    Baskin, D.G.5    Myers Jr., M.G.6    Seeley, R.J.7    Schwartz, M.W.8
  • 93
    • 0017233305 scopus 로고
    • Oxidative metabolism of the cerebral cortex of the rat in severe insulin-induced hypoglycemia
    • Norberg K., Siesjö B.K. Oxidative metabolism of the cerebral cortex of the rat in severe insulin-induced hypoglycemia. J. Neurochem. 26:1976;345-352.
    • (1976) J. Neurochem. , vol.26 , pp. 345-352
    • Norberg, K.1    Siesjö, B.K.2
  • 95
    • 0037727903 scopus 로고    scopus 로고
    • Direct, noninvasive measurement of brain glycogen metabolism in humans
    • Oz G., Henry P.G., Seaquist E.R., Gruetter R. Direct, noninvasive measurement of brain glycogen metabolism in humans. Neurochem. Int. 43(4-5):2003;323-329.
    • (2003) Neurochem. Int. , vol.43 , Issue.45 , pp. 323-329
    • Oz, G.1    Henry, P.G.2    Seaquist, E.R.3    Gruetter, R.4
  • 98
    • 0019861178 scopus 로고
    • Regulation of extra- and intracellular pH in the brain in severe hypoglycemia
    • Pelligrino D., Siesjö B.K. Regulation of extra- and intracellular pH in the brain in severe hypoglycemia. J. Cereb. Blood Flow Metab. 1:1981;85-96.
    • (1981) J. Cereb. Blood Flow Metab. , vol.1 , pp. 85-96
    • Pelligrino, D.1    Siesjö, B.K.2
  • 99
    • 0019417353 scopus 로고
    • Effects of insulin-induced hypoglycemia on intracellular pH and impedance in the cerebral cortex of the rat
    • Pelligrino D., Almquist L.O., Siesjö B.K. Effects of insulin-induced hypoglycemia on intracellular pH and impedance in the cerebral cortex of the rat. Brain Res. 221:1981;129-147.
    • (1981) Brain Res. , vol.221 , pp. 129-147
    • Pelligrino, D.1    Almquist, L.O.2    Siesjö, B.K.3
  • 100
    • 0025132115 scopus 로고
    • Brain glucose utilization and transport and cortical function in chronic vs. acute hypoglycemia
    • Pelligrino D.A., Segil L.J., Albrecht R.F. Brain glucose utilization and transport and cortical function in chronic vs. acute hypoglycemia. Am. J. Physiol. 259:1990;E729-E735.
    • (1990) Am. J. Physiol. , vol.259
    • Pelligrino, D.A.1    Segil, L.J.2    Albrecht, R.F.3
  • 103
    • 0242485280 scopus 로고    scopus 로고
    • Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain
    • Rafiki A., Boulland A., Halestrap J.L., Ottersen A.P., Bergersen O.P. Highly differential expression of the monocarboxylate transporters MCT2 and MCT4 in the developing rat brain. Neuroscience. 122(3):2003;677-688.
    • (2003) Neuroscience , vol.122 , Issue.3 , pp. 677-688
    • Rafiki, A.1    Boulland, A.2    Halestrap, J.L.3    Ottersen, A.P.4    Bergersen, O.P.5
  • 104
    • 50549202600 scopus 로고
    • The glucose-fatty acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus
    • Randle P.J., Garland P.B., Hales C.N., Newsholme E.A. The glucose-fatty acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus. Lancet. I:1963;785-789.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 105
    • 0343674519 scopus 로고    scopus 로고
    • Oxidative stress and HNE conjugation of GLUT3 are increased in the hippocampus of diabetic rats subjected to stress
    • Reagan L.P., Magarinos A.M., Yee D.K., Swzeda L.I., van Bueren A., McCall A.L., McEwen B.S. Oxidative stress and HNE conjugation of GLUT3 are increased in the hippocampus of diabetic rats subjected to stress. Brain Res. 862(1-2):2000;292-300.
    • (2000) Brain Res. , vol.862 , Issue.12 , pp. 292-300
    • Reagan, L.P.1    Magarinos, A.M.2    Yee, D.K.3    Swzeda, L.I.4    Van Bueren, A.5    McCall, A.L.6    McEwen, B.S.7
  • 106
    • 0037023202 scopus 로고    scopus 로고
    • GLUT8 glucose transporter is localized to excitatory and inhibitory neurons in the rat hippocampus
    • Reagan L.P., Rosell D.R., Alves S.E., Hoskin E.K., McCall A.L., Charron M.J., McEwen B.S. GLUT8 glucose transporter is localized to excitatory and inhibitory neurons in the rat hippocampus. Brain Res. 932(1-2):2002;129-134.
    • (2002) Brain Res. , vol.932 , Issue.12 , pp. 129-134
    • Reagan, L.P.1    Rosell, D.R.2    Alves, S.E.3    Hoskin, E.K.4    McCall, A.L.5    Charron, M.J.6    McEwen, B.S.7
  • 107
    • 34250537223 scopus 로고
    • Pathological changes in the central and peripheral nervous system of young long-term diabetics
    • Reske-Nielsen E., Lundback K., Rafaelsen O.J. Pathological changes in the central and peripheral nervous system of young long-term diabetics. Diabetologia. 1:1965;233-237.
    • (1965) Diabetologia , vol.1 , pp. 233-237
    • Reske-Nielsen, E.1    Lundback, K.2    Rafaelsen, O.J.3
  • 108
    • 0033504804 scopus 로고    scopus 로고
    • The effect of hypoglycemic seizures on cognitive function in children with diabetes: A 7-year prospective study
    • Rovet J.F., Ehrlich R.M. The effect of hypoglycemic seizures on cognitive function in children with diabetes: a 7-year prospective study. J. Pediatr. 134(4):1999;503-506.
    • (1999) J. Pediatr. , vol.134 , Issue.4 , pp. 503-506
    • Rovet, J.F.1    Ehrlich, R.M.2
  • 109
    • 0015950390 scopus 로고
    • Regulation of glucose and ketone-body metabolism in brain of anaesthetized rats
    • Ruderman N.B., Ross P.S., Berger M., Goodman M.N. Regulation of glucose and ketone-body metabolism in brain of anaesthetized rats. Biochem. J. 138:1974;1-10.
    • (1974) Biochem. J , vol.138 , pp. 1-10
    • Ruderman, N.B.1    Ross, P.S.2    Berger, M.3    Goodman, M.N.4
  • 110
    • 0036826490 scopus 로고    scopus 로고
    • Brain glycogen: An insulin-sensitive carbohydrate store
    • Seaquist E.R., Gruetter R. Brain glycogen: an insulin-sensitive carbohydrate store. Diabetes Nutr. Metab. 15.5:2002;285-289.
    • (2002) Diabetes Nutr. Metab. , vol.155 , pp. 285-289
    • Seaquist, E.R.1    Gruetter, R.2
  • 111
    • 0035488776 scopus 로고    scopus 로고
    • The effect of insulin on in vivo cerebral glucose concentrations and rates of glucose transport/metabolism in humans
    • Seaquist E.R., Damberg G.S., Tkac I., Gruetter R. The effect of insulin on in vivo cerebral glucose concentrations and rates of glucose transport/metabolism in humans. Diabetes. 50(10):2001;2203-2209.
    • (2001) Diabetes , vol.50 , Issue.10 , pp. 2203-2209
    • Seaquist, E.R.1    Damberg, G.S.2    Tkac, I.3    Gruetter, R.4
  • 112
    • 0026672396 scopus 로고
    • Human small intestine facilitative fructose/glucose transporter (GLUT5) is also present in insulin-responsive tissues and brain. Investigation of biochemical characteristics and translocation
    • Sheperd P.R., Gibbs E.M., Wesslau C., Gould G.W., Kahn B.B. Human small intestine facilitative fructose/glucose transporter (GLUT5) is also present in insulin-responsive tissues and brain. Investigation of biochemical characteristics and translocation. Diabetes. 41:1992;1360-1365.
    • (1992) Diabetes , vol.41 , pp. 1360-1365
    • Sheperd, P.R.1    Gibbs, E.M.2    Wesslau, C.3    Gould, G.W.4    Kahn, B.B.5
  • 113
    • 0034744514 scopus 로고    scopus 로고
    • 13C NMR of intermediary metabolism: Implications for systemic physiology
    • Shulman R.G., Rothman D.L. 13C NMR of intermediary metabolism: implications for systemic physiology. Annu. Rev. Physiol. 63:2001;15-48.
    • (2001) Annu. Rev. Physiol. , vol.63 , pp. 15-48
    • Shulman, R.G.1    Rothman, D.L.2
  • 114
    • 0035933156 scopus 로고    scopus 로고
    • Cerebral energetics and the glycogen shunt: Neurochemical basis of functional imaging
    • Shulman R.G., Hyder F., Rothman D.L. Cerebral energetics and the glycogen shunt: neurochemical basis of functional imaging. Proc. Natl. Acad. Sci. 98(11):2001;6417R-6422R.
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , Issue.11
    • Shulman, R.G.1    Hyder, F.2    Rothman, D.L.3
  • 115
    • 0012412824 scopus 로고
    • Metabolism of substrates in the brain
    • Chichester: Wiley
    • Siesjö B.K. Metabolism of substrates in the brain. Brain Energy Metabolism. 1978;151-209 Wiley, Chichester.
    • (1978) Brain Energy Metabolism , pp. 151-209
    • Siesjö, B.K.1
  • 116
    • 0023836876 scopus 로고
    • Hypoglycemia, brain metabolism, and brain damage
    • Siesjö B.K. Hypoglycemia, brain metabolism, and brain damage. Diabetes/Metab. Rev. 4:1988;113-144.
    • (1988) Diabetes/Metab. Rev. , vol.4 , pp. 113-144
    • Siesjö, B.K.1
  • 119
    • 0028924906 scopus 로고
    • Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression
    • Sipols A.J., Baskin D.G., Schwartz M.W. Effect of intracerebroventricular insulin infusion on diabetic hyperphagia and hypothalamic neuropeptide gene expression. Diabetes. 44(2):1995;147-151.
    • (1995) Diabetes , vol.44 , Issue.2 , pp. 147-151
    • Sipols, A.J.1    Baskin, D.G.2    Schwartz, M.W.3
  • 120
    • 0344011439 scopus 로고    scopus 로고
    • Hypoglycemic neuronal death and cognitive impairment are prevented by poly(ADP-ribose) polymerase inhibitors administered after hypoglycemia
    • Suh S.W., Aoyama K., Chen Y., Garnier P., Matsumori Y., Gum E., Liu J., Swanson R.A. Hypoglycemic neuronal death and cognitive impairment are prevented by poly(ADP-ribose) polymerase inhibitors administered after hypoglycemia. J. Neurosci. 23(33):2003;10681-10690.
    • (2003) J. Neurosci. , vol.23 , Issue.33 , pp. 10681-10690
    • Suh, S.W.1    Aoyama, K.2    Chen, Y.3    Garnier, P.4    Matsumori, Y.5    Gum, E.6    Liu, J.7    Swanson, R.A.8
  • 121
    • 0023757322 scopus 로고
    • Chronic exposure to high glucose decreases myo-inositol in cultured cerebral microvascular pericytes but not in endothelium
    • Sussman I., Carson M.P., Schultz V., Wu X.P., McCall A.L., Ruderman N.B., Tornheim K. Chronic exposure to high glucose decreases myo-inositol in cultured cerebral microvascular pericytes but not in endothelium. Diabetologia. 31:1988;771-775.
    • (1988) Diabetologia , vol.31 , pp. 771-775
    • Sussman, I.1    Carson, M.P.2    Schultz, V.3    Wu, X.P.4    McCall, A.L.5    Ruderman, N.B.6    Tornheim, K.7
  • 122
    • 0035891258 scopus 로고    scopus 로고
    • Increased intracranial arterial resistance in patients with type 2 diabetes mellitus
    • Tkac I., Troscak M., Javorsky M., Petrik R., Tomcova M. Increased intracranial arterial resistance in patients with type 2 diabetes mellitus. Wien. Klin. Wochenschr. 113(22):2001;870-873.
    • (2001) Wien. Klin. Wochenschr. , vol.113 , Issue.22 , pp. 870-873
    • Tkac, I.1    Troscak, M.2    Javorsky, M.3    Petrik, R.4    Tomcova, M.5
  • 123
    • 0030972576 scopus 로고    scopus 로고
    • Chronic insulin hypoglycemia induces GLUT-3 protein in rat brain neurons
    • Uehara Y., Nipper V., McCall A.L. Chronic insulin hypoglycemia induces GLUT-3 protein in rat brain neurons. Am. J. Physiol: Endocrinol. Metab. 272.4:1997;E716-E719.
    • (1997) Am. J. Physiol: Endocrinol. Metab. , vol.2724
    • Uehara, Y.1    Nipper, V.2    McCall, A.L.3
  • 125
    • 0025504552 scopus 로고
    • Reduced regional cerebral blood flow in aged noninsulin-dependent diabetic patients with no history of cerebrovascular disease: Evaluation by N-isopropyl-123I-p-iodoamphetamine with single-photon emission computed tomography
    • Wakisaka M., Nagamachi S., Inoue K., Morotomi Y., Nunoi K., Fujishima M. Reduced regional cerebral blood flow in aged noninsulin-dependent diabetic patients with no history of cerebrovascular disease: evaluation by N-isopropyl-123I-p-iodoamphetamine with single-photon emission computed tomography. J. Diabetes Its Complicat. 4:1990;170-174.
    • (1990) J. Diabetes Its Complicat. , vol.4 , pp. 170-174
    • Wakisaka, M.1    Nagamachi, S.2    Inoue, K.3    Morotomi, Y.4    Nunoi, K.5    Fujishima, M.6
  • 126
    • 0022344980 scopus 로고
    • Hypoglycemia-induced neuronal damage prevented by an N-Methyl-D-Aspartate antagonist
    • Wieloch T. Hypoglycemia-induced neuronal damage prevented by an N-Methyl-D-Aspartate antagonist. Science. 230:1985;681-683.
    • (1985) Science , vol.230 , pp. 681-683
    • Wieloch, T.1
  • 127
    • 0021273322 scopus 로고
    • Influence of severe hypoglycemia on brain extracellular calcium and potassium activities, energy, and phospholipid metabolism
    • Wieloch T., Harris R.J., Symon L., Siesjö B.K. Influence of severe hypoglycemia on brain extracellular calcium and potassium activities, energy, and phospholipid metabolism. J. Neurochem. 43:1984;160-168.
    • (1984) J. Neurochem. , vol.43 , pp. 160-168
    • Wieloch, T.1    Harris, R.J.2    Symon, L.3    Siesjö, B.K.4


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