Histamine-induced inhibition of leukotriene biosynthesis in human neutrophils: Involvement of the H 2 receptor and cAMP

British Journal of Pharmacology

Volumn 141, Issue 4, 2004, Pages 552-561

  Flamand, Nicolas ^a   Plante, Hendrick ^a   Picard, Serge ^a   Laviolette, Michel ^b   Borgeat, Pierre ^a  

^a Université Laval   (Canada)

^b UNIVERSITÉ LAVAL   (Canada)

Author keywords

5 Lipoxygenase; Arachidonic acid; Autacoid; cAMP; Histamine; Leukocyte; Leukotriene; Lipid mediator; PKA

Indexed keywords

ADENOSINE; ARACHIDONATE 5 LIPOXYGENASE; CALCIMYCIN; CIMETIDINE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; G PROTEIN COUPLED RECEPTOR; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; HISTAMINE H2 RECEPTOR; HISTAMINE H2 RECEPTOR ANTAGONIST; HISTAMINE H3 RECEPTOR ANTAGONIST; HISTAMINE H4 RECEPTOR ANTAGONIST; KT 5720; LEUKOTRIENE; LIGAND; LIPOXYGENASE INHIBITOR; MEPYRAMINE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROSTAGLANDIN E2; RANITIDINE; THAPSIGARGIN; TIOTIDINE; UNCLASSIFIED DRUG;

ALLERGY; ARACHIDONIC ACID METABOLISM; ARTICLE; ASTHMA; CELL NUCLEUS MEMBRANE; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ASSAY; ENZYME INHIBITION; HISTAMINE RELEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; INFLAMMATION; INHIBITION KINETICS; MEDIATOR RELEASE; NEUTROPHIL; PRIORITY JOURNAL; RECEPTOR BINDING; REGULATORY MECHANISM;

ARACHIDONATE 5-LIPOXYGENASE; ARACHIDONIC ACID; CALCIUM; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DEPRESSION, CHEMICAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; HISTAMINE; HISTAMINE AGONISTS; HISTAMINE ANTAGONISTS; HUMANS; ISOQUINOLINES; LEUKOTRIENE B4; LEUKOTRIENES; NEUTROPHILS; NUCLEAR ENVELOPE; PHOSPHOLIPASES A; RECEPTORS, HISTAMINE H2; STIMULATION, CHEMICAL; SULFONAMIDES; TRANSLOCATION, GENETIC;

EID: 1842610701     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705654     Document Type: Article

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