Evolutionarily conserved function of Gbx2 in anterior hindbrain development

Developmental Dynamics

Volumn 240, Issue 4, 2011, Pages 828-838

  Burroughs Garcia, Jessica ^a   Sittaramane, Vinoth ^a   Chandrasekhar, Anand ^a   Waters, Samuel T ^a  

^a UNIVERSITY OF MISSOURI   (United States)

Author keywords

Anterior hindbrain; gbx2; Gbx2; Isthmus; Midbrain hindbrain boundary; Mouse; Zebrafish

Indexed keywords

BRAIN PROTEIN; HOMEODOMAIN PROTEIN; MESSENGER RNA; PROTEIN GBX2; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; CARBOXY TERMINAL SEQUENCE; CELL DEATH; CELL PROLIFERATION; CONSERVATION GENETICS; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; GENE FUNCTION; KNOCKOUT GENE; MOLECULAR EVOLUTION; MOTONEURON; NONHUMAN; PERIKARYON; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RHOMBENCEPHALON; TRIGEMINAL NERVE; ZEBRA FISH;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BIOLOGICAL EVOLUTION; CELL DEATH; CELL PROLIFERATION; CONSERVED SEQUENCE; EMBRYO, MAMMALIAN; EMBRYO, NONMAMMALIAN; EMBRYONIC DEVELOPMENT; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HOMEODOMAIN PROTEINS; MICE; RHOMBENCEPHALON; ZEBRAFISH; ZEBRAFISH PROTEINS;

DANIO RERIO; MUS;

EID: 79952636213     PISSN: 10588388     EISSN: 10970177     Source Type: Journal    
DOI: 10.1002/dvdy.22589     Document Type: Article

References (54)

1. Bally-Cuif L, Wassef M. 1995. Determination events in the nervous system of the vertebrate embryo. Curr Opin Genet Dev 5: 450-458.
2. Bouillet P, Chazaud C, Oulad-Abdelghani M, Dolle P, Chambon P. 1995. Sequence and expression pattern of the Stra7 (Gbx-2) homeobox-containing gene induced by retinoic acid in P19 embryonal carcinoma cells. Dev Dyn 204: 372-382.
3. Brenner RM, Slayden OD, Rodgers WH, Critchley HO, Carroll R, Nie XJ, Mah K. 2003. Immunocytochemical assessment of mitotic activity with an antibody to phosphorylated histone H3 in the macaque and human endometrium. Hum Reprod 18: 1185-1193.
4. Broccoli V, Boncinelli E, Wurst W. 1999. The caudal limit of Otx2 expression positions the isthmic organizer. Nature 401: 164-168.
5. Brodski C, Weisenhorn DM, Signore M, Sillaber I, Oesterheld M, Broccoli V, Acampora D, Simeone A, Wurst W. 2003. Location and size of dopaminergic and serotonergic cell populations are controlled by the position of the midbrain-hindbrain organizer. J Neurosci 23: 4199-4207.
6. Carroll SB. 2000. Endless forms: the evolution of gene regulation and morphological diversity. Cell 101: 577-580.
7. Chandrasekhar A. 2004. Turning heads: development of vertebrate branchiomotor neurons. Dev Dyn 229: 143-161.
8. Chandrasekhar A, Moens CB, Warren JT, Jr., Kimmel CB, Kuwada JY. 1997. Development of branchiomotor neurons in zebrafish. Development 124: 2633-2644.
9. Chapman G, Rathjen PD. 1995. Sequence and evolutionary conservation of the murine Gbx-2 homeobox gene. FEBS Lett 364: 289-292.
10. Dermitzakis ET, Clark AG. 2002. Evolution of transcription factor binding sites in Mammalian gene regulatory regions: conservation and turnover. Mol Biol Evol 19: 1114-1121.
11. Heimbucher T, Murko C, Bajoghli B, Aghaallaei N, Huber A, Stebegg R, Eberhard D, Fink M, Simeone A, Czerny T. 2007. Gbx2 and Otx2 interact with the WD40 domain of Groucho/Tle corepressors. Mol Cell Biol 27: 340-351.
12. Higashijima S, Hotta Y, Okamoto H. 2000. Visualization of cranial motor neurons in live transgenic zebrafish expressing green fluorescent protein under the control of the islet-1 promoter/enhancer. J Neurosci 20: 206-218.
13. Houart C, Westerfield M, Wilson SW. 1998. A small population of anterior cells patterns the forebrain during zebrafish gastrulation. Nature 391: 788-792.
14. Hsia CC, McGinnis W. 2003. Evolution of transcription factor function. Curr Opin Genet Dev 13: 199-206.
15. Islam ME, Kikuta H, Inoue F, Kanai M, Kawakami A, Parvin MS, Takeda H, Yamasu K. 2006. Three enhancer regions regulate gbx2 gene expression in the isthmic region during zebrafish development. Mech Dev 123: 907-924.
16. Jimenez G, Paroush Z, Ish-Horowicz D. 1997. Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed. Genes Dev 11: 3072-3082.
17. Katahira T, Sato T, Sugiyama S, Okafuji T, Araki I, Funahashi J, Nakamura H. 2000. Interaction between Otx2 and Gbx2 defines the organizing center for the optic tectum. Mech Dev 91: 43-52.
18. Kay BK, Williamson MP, Sudol M. 2000. The importance of being proline: the interaction of proline-rich motifs in signaling proteins with their cognate domains. Faseb J 14: 231-241.
19. Kikuta H, Kanai M, Ito Y, Yamasu K. 2003. gbx2 Homeobox gene is required for the maintenance of the isthmic region in the zebrafish embryonic brain. Dev Dyn 228: 433-450.
20. Li B, Kuriyama S, Moreno M, Mayor R. 2009. The posteriorizing gene Gbx2 is a direct target of Wnt signalling and the earliest factor in neural crest induction. Development 136: 3267-3278.
21. Li JY, Joyner AL. 2001. Otx2 and Gbx2 are required for refinement and not induction of mid-hindbrain gene expression. Development 128: 4979-4991.
22. Li JY, Lao Z, Joyner AL. 2002. Changing requirements for Gbx2 in development of the cerebellum and maintenance of the mid/hindbrain organizer. Neuron 36: 31-43.
23. Li JY, Lao Z, Joyner AL. 2005. New regulatory interactions and cellular responses in the isthmic organizer region revealed by altering Gbx2 expression. Development 132: 1971-1981.
24. Lin Z, Cantos R, Patente M, Wu DK. 2005. Gbx2 is required for the morphogenesis of the mouse inner ear: a downstream candidate of hindbrain signaling. Development 132: 2309-2318.
25. Liu A, Joyner AL. 2001a. Early anterior/posterior patterning of the midbrain and cerebellum. Annu Rev Neurosci 24: 869-896.
26. Liu A, Joyner AL. 2001b. EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region. Development 128: 181-191.
27. Lumsden A, Krumlauf R. 1996. Patterning the vertebrate neuraxis. Science 274: 1109-1115.
28. Mann RS, Chan SK. 1996. Extra specificity from extradenticle: the partnership between HOX and PBX/EXD homeodomain proteins. Trends Genet 12: 258-262.
29. Martinez-Barbera JP, Signore M, Boyl PP, Puelles E, Acampora D, Gogoi R, Schubert F, Lumsden A, Simeone A. 2001. Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2. Development 128: 4789-4800.
30. McClintock JM, Kheirbek MA, Prince VE. 2002. Knockdown of duplicated zebrafish hoxb1 genes reveals distinct roles in hindbrain patterning and a novel mechanism of duplicate gene retention. Development 129: 2339-2354.
31. Mermod N, O'Neill EA, Kelly TJ, Tjian R. 1989. The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domain. Cell 58: 741-753.
32. Millet S, Campbell K, Epstein DJ, Losos K, Harris E, Joyner AL. 1999. A role for Gbx2 in repression of Otx2 and positioning the mid/hindbrain organizer. Nature 401: 161-164.
33. Miyashita T, Harigai M, Hanada M, Reed JC. 1994. Identification of a p53-dependent negative response element in the bcl-2 gene. Cancer Res 54: 3131-3135.
34. Moens CB, Prince VE. 2002. Constructing the hindbrain: insights from the zebrafish. Dev Dyn 224: 1-17.
35. Pfeffer PL, Gerster T, Lun K, Brand M, Busslinger M. 1998. Characterization of three novel members of the zebrafish Pax2/5/8 family: dependency of Pax5 and Pax8 expression on the Pax2.1 (noi) function. Development 125: 3063-3074.
36. Prince VE, Moens CB, Kimmel CB, Ho RK. 1998. Zebrafish hox genes: expression in the hindbrain region of wild-type and mutants of the segmentation gene, valentino. Development 125: 393-406.
37. Rhinn M, Brand M. 2001. The midbrain: hindbrain boundary organizer. Curr Opin Neurobiol 11: 34-42.
38. Rhinn M, Lun K, Amores A, Yan YL, Postlethwait JH, Brand M. 2003. Cloning, expression and relationship of zebrafish gbx1 and gbx2 genes to Fgf signaling. Mech Dev 120: 919-936.
39. Rhinn M, Lun K, Ahrendt R, Geffarth M, Brand M. 2009. Zebrafish gbx1 refines the midbrain-hindbrain boundary border and mediates the Wnt8 posteriorization signal. Neural Dev 4: 12.
40. Robu ME, Larson JD, Nasevicius A, Beiraghi S, Brenner C, Farber SA, Ekker SC. 2007. p53 activation by knockdown technologies. PLoS Genet 3: e78.
41. Roperch JP, Alvaro V, Prieur S, Tuynder M, Nemani M, Lethrosne F, Piouffre L, Gendron MC, Israeli D, Dausset J, Oren M, Amson R, Telerman A. 1998. Inhibition of presenilin 1 expression is promoted by p53 and p21WAF-1 and results in apoptosis and tumor suppression. Nat Med 4: 835-838.
42. Schilling TF, Prince V, Ingham PW. 2001. Plasticity in zebrafish hox expression in the hindbrain and cranial neural crest. Dev Biol 231: 201-216.
43. Shimamura K, Rubenstein JL. 1997. Inductive interactions direct early regionalization of the mouse forebrain. Development 124: 2709-2718.
44. Simeone A. 2000. Positioning the isthmic organizer where Otx2 and Gbx2meet. Trends Genet 16: 237-240.
45. Smith ST, Jaynes JB. 1996. A conserved region of engrailed, shared among all en-, gsc-, Nk1-, Nk2- and msh-class homeoproteins, mediates active transcriptional repression in vivo. Development 122: 3141-3150.
46. Tucker B, Lardelli M. 2007. A rapid apoptosis assay measuring relative acridine orange fluorescence in zebrafish embryos. Zebrafish 4: 113-116.
47. Vanderlaan G, Tyurina OV, Karlstrom RO, Chandrasekhar A. 2005. Gli function is essential for motor neuron induction in zebrafish. Dev Biol 282: 550-570.
48. von Bubnoff A, Schmidt JE, Kimelman D. 1996. The Xenopus laevis homeobox gene Xgbx-2 is an early marker of anteroposterior patterning in the ectoderm. Mech Dev 54: 149-160.
49. Wassarman KM, Lewandoski M, Campbell K, Joyner AL, Rubenstein JL, Martinez S, Martin GR. 1997. Specification of the anterior hindbrain and establishment of a normal mid/hindbrain organizer is dependent on Gbx2 gene function. Development 124: 2923-2934.
50. Waters ST, Lewandoski M. 2006. A threshold requirement for Gbx2 levels in hindbrain development. Development 133: 1991-2000.
51. Waters ST, Wilson CP, Lewandoski M. 2003. Cloning and embryonic expression analysis of the mouse Gbx1 gene. Gene Expr Patterns 3: 313-317.
52. Westerfield M. 2000. The zebrafish book. A guide for the laboratory use of zebrafish (Danio rerio). 4th edition. Eugene, Oregon: University of Oregon Press.
53. Wingate RJ. 2001. The rhombic lip and early cerebellar development. Curr Opin Neurobiol 11: 82-88.
54. Wurst W, Bally-Cuif L. 2001. Neural plate patterning: upstream and downstream of the isthmic organizer. Nat Rev Neurosci 2: 99-108.