An Ift80 mouse model of short rib polydactyly syndromes shows defects in hedgehog signalling without loss or malformation of cilia

Human Molecular Genetics

Volumn 20, Issue 7, 2011, Pages 1306-1314

  Rix, Suzanne ^a   Calmont, Amelie ^a   Scambler, Peter J ^a   Beales, Philip L ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; INTRAFLAGELLAR TRANSPORT 80 PROTEIN; SONIC HEDGEHOG PROTEIN; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MALFORMATION; CHONDRODYSPLASIA; CILIARY MOTILITY; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EMBRYOPATHY; GENE CASSETTE; GENOTYPE; GROWTH DISORDER; HOMOZYGOTE; JEUNE ASPHYXIATING THORACIC DYSTROPHY; MOUSE; NEWBORN; NONHUMAN; PHENOTYPE; POLYDACTYLY; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; RIB MALFORMATION; SIGNAL TRANSDUCTION; SURVIVAL; WILD TYPE;

ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; CILIA; DISEASE MODELS, ANIMAL; FIBROBLASTS; HEDGEHOG PROTEINS; HUMANS; MICE; MICE, MUTANT STRAINS; SHORT RIB-POLYDACTYLY SYNDROME; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

ERINACEIDAE; MURINAE;

EID: 79952586302     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr013     Document Type: Article

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