Inhibition of neural crest migration underlies craniofacial dysmorphology and Hirschsprung's disease in Bardet-Biedl syndrome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 18, 2008, Pages 6714-6719

  Tobin, Jonathan L ^a   Di Franco, Matt ^b   Eichers, Erica ^c   May Simera, Helen ^a   Garcia, Monica ^c   Yan, Jiong ^c   Quinlan, Robyn ^a   Justice, Monica J ^c   Hennekam, Raoul C ^a,f   Briscoe, James ^d   Tada, Masazumi ^e   Mayor, Roberto ^e   Burns, Alan J ^a   Lupski, James R ^c   Hammond, Peter ^a,b   Beales, Philip L ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

^d NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^e UNIVERSITY COLLEGE LONDON   (United Kingdom)

^f UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Cell migration; Cilia; Sonic hedgehog; Wnt

Indexed keywords

SONIC HEDGEHOG PROTEIN; WNT PROTEIN; ZEBRAFISH PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; BARDET BIEDL SYNDROME; CELL MIGRATION; CHROMOSOME ABERRATION; CONTROLLED STUDY; CRANIOFACIAL MALFORMATION; HIRSCHSPRUNG DISEASE; HUMAN; MOUSE; NEURAL CREST; NEURAL CREST CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; ANIMAL; CELL MOTION; CELL STRAIN 3T3; CONGENITAL MALFORMATION; EUKARYOTIC FLAGELLUM; GASTROINTESTINAL MOTILITY; GENETICS; INTESTINE INNERVATION; METABOLISM; MUTATION; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; THREE DIMENSIONAL IMAGING; ZEBRA FISH;

DANIO RERIO; ERINACEIDAE;

ANIMALS; BARDET-BIEDL SYNDROME; CELL MOVEMENT; CILIA; CRANIOFACIAL ABNORMALITIES; ENTERIC NERVOUS SYSTEM; GASTROINTESTINAL MOTILITY; HEDGEHOG PROTEINS; HIRSCHSPRUNG DISEASE; HUMANS; IMAGING, THREE-DIMENSIONAL; MICE; MUTATION; NEURAL CREST; NIH 3T3 CELLS; PHENOTYPE; SIGNAL TRANSDUCTION; WNT PROTEINS; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 44349147745     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0707057105     Document Type: Article

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