-
1
-
-
0032900953
-
Biochemical, cellular, and pharmacological aspects of the multidrug transporter
-
DOI 10.1146/annurev.pharmtox.39.1.361
-
Ambudkar SV, Dey S, Hrycyna CA, Ramachandra M, Pastan I, Gottesman MM. 1999. Biochemical, cellular, and pharmacological aspects of the multidrug transporter. Annu Rev Pharmacol Toxicol 39:361-398. (Pubitemid 29222564)
-
(1999)
Annual Review of Pharmacology and Toxicology
, vol.39
, pp. 361-398
-
-
Ambudkar, S.V.1
Dey, S.2
Hrycyna, C.A.3
Ramachandra, M.4
Pastan, I.5
Gottesman, M.M.6
-
2
-
-
0034827621
-
Reversing effect of agosterol A, a spongean sterol acetate, on multidrug resistance in human carcinoma cells
-
Aoki S, Chen ZS, Higasiyama K, Setiawan A, Akiyama S, Kobayashi M. 2001. Reversing effect of agosterol A, a spongean sterol acetate, on multidrug resistance in human carcinoma cells. Jpn J Cancer Res 92:886-895. (Pubitemid 32894100)
-
(2001)
Japanese Journal of Cancer Research
, vol.92
, Issue.8
, pp. 886-895
-
-
Aoki, S.1
Chen, Z.-S.2
Higasiyama, K.3
Setiawan, A.4
Akiyama, S.-I.5
Kobayashi, M.6
-
3
-
-
73949103220
-
Molecular mechanism of ATP-dependent solute transport by multidrug resistance-associated protein 1
-
Chang XB. 2010. Molecular mechanism of ATP-dependent solute transport by multidrug resistance-associated protein 1. Methods Mol Biol 596:223-249.
-
(2010)
Methods Mol Biol
, vol.596
, pp. 223-249
-
-
Chang, X.B.1
-
4
-
-
4344563023
-
Reversal of P-gp mediated multidrug resistance in-vitro and in-vivo by FG020318
-
DOI 10.1211/0022357043879
-
Chen LM, Liang YJ, Ruan JW, Ding Y, Wang XW, Shi Z, Gu LQ, Yang XP, Fu LW. 2004. Reversal of P-gp mediated multidrug resistance in-vitro and in-vivo by FG020318. J Pharm Pharmacol 56:1061-1066. (Pubitemid 39140063)
-
(2004)
Journal of Pharmacy and Pharmacology
, vol.56
, Issue.8
, pp. 1061-1066
-
-
Chen, L.-M.1
Liang, Y.-J.2
Ruan, J.-W.3
Ding, Y.4
Wang, X.-W.5
Shi, Z.6
Gu, L.-Q.7
Yang, X.-P.8
Fu, L.-W.9
-
5
-
-
75149143463
-
Reversal of P-gp-mediated multidrug resistance by bromotetrandrine in vivo is associated with enhanced accumulation of chemotherapeutical drug in tumor tissue
-
Chen LM, Liang YJ, Zhang X, Su XD, Dai CL, Wang FP, Yan YY, Tao LY, Fu LW. 2009. Reversal of P-gp-mediated multidrug resistance by bromotetrandrine in vivo is associated with enhanced accumulation of chemotherapeutical drug in tumor tissue. Anticancer Res 29:4597-4604.
-
(2009)
Anticancer Res
, vol.29
, pp. 4597-4604
-
-
Chen, L.M.1
Liang, Y.J.2
Zhang, X.3
Su, X.D.4
Dai, C.L.5
Wang, F.P.6
Yan, Y.Y.7
Tao, L.Y.8
Fu, L.W.9
-
6
-
-
77954513679
-
Euphorbiasteroid reverses P-glycoprotein-mediated multi-drug resistance in human sarcoma cell line MES-SA/Dx5
-
Choi JS, Kang NS, Min YK, Kim SH. 2009. Euphorbiasteroid reverses P-glycoprotein-mediated multi-drug resistance in human sarcoma cell line MES-SA/Dx5. Phytother Res 24:1042-1046.
-
(2009)
Phytother Res
, vol.24
, pp. 1042-1046
-
-
Choi, J.S.1
Kang, N.S.2
Min, Y.K.3
Kim, S.H.4
-
7
-
-
0023033333
-
Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells
-
Cornwell MM, Gottesman MM, Pastan IH. 1986. Increased vinblastine binding to membrane vesicles from multidrug-resistant KB cells. J Biol Chem 261:7921-7928. (Pubitemid 17208724)
-
(1986)
Journal of Biological Chemistry
, vol.261
, Issue.17
, pp. 7921-7928
-
-
Cornwell, M.M.1
Gottesman, M.M.2
Pastan, I.H.3
-
8
-
-
34547850491
-
Tetrandrine achieved plasma concentrations capable of reversing MDR in vitro and had no apparent effect on doxorubicin pharmacokinetics in mice
-
DOI 10.1007/s00280-007-0420-0
-
Dai CL, Xiong HY, Tang LF, Zhang X, Liang YJ, Zeng MS, Chen LM, Wang XH, Fu LW. 2007. Tetrandrine achieved plasma concentrations capable of reversing MDR in vitro and had no apparent effect on doxorubicin pharmacokinetics in mice. Cancer Chemother Pharmacol 60:741-750. (Pubitemid 47247285)
-
(2007)
Cancer Chemotherapy and Pharmacology
, vol.60
, Issue.5
, pp. 741-750
-
-
Dai, C.-L.1
Xiong, H.-Y.2
Tang, L.-F.3
Zhang, X.4
Liang, Y.-J.5
Zeng, M.-S.6
Chen, L.-M.7
Wang, X.-H.8
Fu, L.-W.9
-
9
-
-
54249157033
-
Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2
-
Dai CL, Tiwari AK, Wu CP, Su XD, Wang SR, Liu DG, Ashby CR, Jr, Huang Y, Robey RW, Liang YJ, Chen LM, Shi CJ, Ambudkar SV, Chen ZS, Fu LW. 2008. Lapatinib (Tykerb, GW572016) reverses multidrug resistance in cancer cells by inhibiting the activity of ATP-binding cassette subfamily B member 1 and G member 2. Cancer Res 68:7905-7914.
-
(2008)
Cancer Res
, vol.68
, pp. 7905-7914
-
-
Dai, C.L.1
Tiwari, A.K.2
Wu, C.P.3
Su, X.D.4
Wang, S.R.5
Liu, D.G.6
Ashby Jr., C.R.7
Huang, Y.8
Robey, R.W.9
Liang, Y.J.10
Chen, L.M.11
Shi, C.J.12
Ambudkar, S.V.13
Chen, Z.S.14
Fu, L.W.15
-
10
-
-
67349207358
-
Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2
-
Dai CL, Liang YJ, Wang YS, Tiwari AK, Yan YY, Wang F, Chen ZS, Tong XZ, Fu LW. 2009. Sensitization of ABCG2-overexpressing cells to conventional chemotherapeutic agent by sunitinib was associated with inhibiting the function of ABCG2. Cancer Lett 279:74-83.
-
(2009)
Cancer Lett
, vol.279
, pp. 74-83
-
-
Dai, C.L.1
Liang, Y.J.2
Wang, Y.S.3
Tiwari, A.K.4
Yan, Y.Y.5
Wang, F.6
Chen, Z.S.7
Tong, X.Z.8
Fu, L.W.9
-
11
-
-
0034917716
-
The human ATP-binding cassette (ABC) transporter superfamily
-
DOI 10.1101/gr.GR-1649R
-
Dean M, Rzhetsky A, Allikmets R. 2001. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res 11:1156-1166. (Pubitemid 32677289)
-
(2001)
Genome Research
, vol.11
, Issue.7
, pp. 1156-1166
-
-
Dean, M.1
Rzhetsky, A.2
Allikmets, R.3
-
12
-
-
34249334671
-
FG020326-loaded nanoparticle with PEG and PDLLA improved pharmacodynamics of reversing multidrug resistance in vitro and in vivo
-
Deng WJ, Yang XQ, Liang YJ, Chen LM, Yan YY, Shuai XT, Fu LW. 2007. FG020326-loaded nanoparticle with PEG and PDLLA improved pharmacodynamics of reversing multidrug resistance in vitro and in vivo. Acta Pharmacol Sin 28:913-920.
-
(2007)
Acta Pharmacol Sin
, vol.28
, pp. 913-920
-
-
Deng, W.J.1
Yang, X.Q.2
Liang, Y.J.3
Chen, L.M.4
Yan, Y.Y.5
Shuai, X.T.6
Fu, L.W.7
-
13
-
-
33644534548
-
New macrocyclic lathyrane diterpenes, from Euphorbia lagascae, as inhibitors of multidrug resistance of tumour cells
-
DOI 10.1055/s-2005-873196
-
Duarte N, Gyemant N, Abreu PM, Molnar J, Ferreira MJ. 2006. New macrocyclic lathyrane diterpenes, from Euphorbia lagascae, as inhibitors of multidrug resistance of tumour cells. Planta Med 72:162-168. (Pubitemid 43293872)
-
(2006)
Planta Medica
, vol.72
, Issue.2
, pp. 162-168
-
-
Duarte, N.1
Gyemant, N.2
Abreu, P.M.3
Molnar, J.4
Ferreira, M.J.U.5
-
14
-
-
33750953574
-
Apoptosis induction and modulation of P-glycoprotein mediated multidrug resistance by new macrocyclic lathyrane-type diterpenoids
-
DOI 10.1016/j.bmc.2006.09.028, PII S0968089606007590
-
Duarte N, Varga A, Cherepnev G, Radics R, Molnar J, Ferreira MJ. 2007. Apoptosis induction and modulation of P-glycoprotein mediated multidrug resistance by new macrocyclic lathyrane-type diterpenoids. Bioorg Med Chem 15:546-554. (Pubitemid 44738549)
-
(2007)
Bioorganic and Medicinal Chemistry
, vol.15
, Issue.1
, pp. 546-554
-
-
Duarte, N.1
Varga, A.2
Cherepnev, G.3
Radics, R.4
Molnar, J.5
Ferreira, M.-J.U.6
-
15
-
-
53249105258
-
Synergistic interaction between p-glycoprotein modulators and epirubicine on resistant cancer cells
-
Duarte N, Jardanhazy A, Molnar J, Hilgeroth A, Ferreira MJ. 2008. Synergistic interaction between p-glycoprotein modulators and epirubicine on resistant cancer cells. Bioorg Med Chem 16:9323-9330.
-
(2008)
Bioorg Med Chem
, vol.16
, pp. 9323-9330
-
-
Duarte, N.1
Jardanhazy, A.2
Molnar, J.3
Hilgeroth, A.4
Ferreira, M.J.5
-
16
-
-
35348965689
-
New MDR modulators and apoptosis inducers from Euphorbia species
-
Engi H, Vasas A, Redei D, Molnar J, Hohmann J. 2007. New MDR modulators and apoptosis inducers from Euphorbia species. Anticancer Res 27:3451-3458. (Pubitemid 47607575)
-
(2007)
Anticancer Research
, vol.27
, Issue.5 A
, pp. 3451-3458
-
-
Engi, H.1
Vasas, A.2
Redei, D.3
Molnar, J.4
Hohmann, J.5
-
17
-
-
75149114141
-
Multidrug efflux pumps: Substrate selection in ATP-binding cassette multidrug efflux pumps-First come, first served?
-
Ernst R, Kueppers P, Stindt J, Kuchler K, Schmitt L. 2010. Multidrug efflux pumps: Substrate selection in ATP-binding cassette multidrug efflux pumps-First come, first served? FEBS J 277:540-549.
-
(2010)
FEBS J
, vol.277
, pp. 540-549
-
-
Ernst, R.1
Kueppers, P.2
Stindt, J.3
Kuchler, K.4
Schmitt, L.5
-
18
-
-
27944468181
-
The effects of jatrophane derivatives on the reversion of MDR1- And MRP-mediated multidrug resistance in the MDA-MB-231 (HTB-26) cell line
-
Ferreira MJ, Gyemant N, Madureira AM, Tanaka M, Koos K, Didziapetris R, Molnar J. 2005. The effects of jatrophane derivatives on the reversion of MDR1- and MRP-mediated multidrug resistance in the MDA-MB-231 (HTB-26) cell line. Anticancer Res 25:4173-4178. (Pubitemid 41665201)
-
(2005)
Anticancer Research
, vol.25
, Issue.6 B
, pp. 4173-4178
-
-
Ferreira, M.-J.U.1
Gyemant, N.2
Madureira, A.M.3
Tanaka, M.4
Koos, K.5
Didziapetris, R.6
Molnar, J.7
-
19
-
-
0036164671
-
The multidrug resistance of tumour cells was reversed by tetrandrine in vitro and in xenografts derived from human breast adenocarcinoma MCF-7/adr cells
-
DOI 10.1016/S0959-8049(01)00356-2, PII S0959804901003562
-
Fu LW, Zhang YM, Liang YJ, Yang XP, Pan QC. 2002. The multidrug resistance of tumour cells was reversed by tetrandrine in vitro and in xenografts derived from human breast adenocarcinoma MCF-7/adr cells. Eur J Cancer 38:418-426. (Pubitemid 34121971)
-
(2002)
European Journal of Cancer
, vol.38
, Issue.3
, pp. 418-426
-
-
Fu, L.W.1
Zhang, Y.M.2
Liang, Y.J.3
Yang, X.P.4
Pan, Q.C.5
-
20
-
-
2542491777
-
The role of ABC transporters in drug resistance, metabolism and toxicity
-
Glavinas H, Krajcsi P, Cserepes J, Sarkadi B. 2004. The role of ABC transporters in drug resistance, metabolism and toxicity. Curr Drug Deliv 1:27-42.
-
(2004)
Curr Drug Deliv
, vol.1
, pp. 27-42
-
-
Glavinas, H.1
Krajcsi, P.2
Cserepes, J.3
Sarkadi, B.4
-
21
-
-
0023813001
-
Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ADM cells
-
Hamada H, Tsuruo T. 1988. Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ADM cells. Cancer Res 48:4926-4932.
-
(1988)
Cancer Res
, vol.48
, pp. 4926-4932
-
-
Hamada, H.1
Tsuruo, T.2
-
22
-
-
66449129065
-
Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures
-
Jiao W, Dong W, Li Z, Deng M, Lu R. 2009. Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures. Bioorg Med Chem 17:4786-4792.
-
(2009)
Bioorg Med Chem
, vol.17
, pp. 4786-4792
-
-
Jiao, W.1
Dong, W.2
Li, Z.3
Deng, M.4
Lu, R.5
-
23
-
-
0034947674
-
From MDR to MXR: New understanding of multidrug resistance systems, their properties and clinical significance
-
Litman T, Druley TE, Stein WD, Bates SE. 2001. From MDR to MXR: New understanding of multidrug resistance systems, their properties and clinical significance. Cell Mol Life Sci 58:931-959. (Pubitemid 32652819)
-
(2001)
Cellular and Molecular Life Sciences
, vol.58
, Issue.7
, pp. 931-959
-
-
Litman, T.1
Druley, T.E.2
Stein, W.D.3
Bates, S.E.4
-
24
-
-
34948887693
-
ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein
-
DOI 10.1038/sj.bjc.6603985, PII 6603985
-
Mi Y, Lou L. 2007. ZD6474 reverses multidrug resistance by directly inhibiting the function of P-glycoprotein. Br J Cancer 97:934-940. (Pubitemid 47519322)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.7
, pp. 934-940
-
-
Mi, Y.1
Lou, L.2
-
25
-
-
0042068263
-
A functional study on polymorphism of the ATP-binding cassette transporter ABCG2: Critical role of arginine-482 in methotrexate transport
-
DOI 10.1042/BJ20030150
-
Mitomo H, Kato R, Ito A, Kasamatsu S, Ikegami Y, Kii I, Kudo A, Kobatake E, Sumino Y, Ishikawa T. 2003. A functional study on polymorphism of the ATP-binding cassette transporter ABC G2: Critical role of arginine-482 in methotrexate transport. Biochem J 373:767-774. (Pubitemid 36981086)
-
(2003)
Biochemical Journal
, vol.373
, Issue.3
, pp. 767-774
-
-
Mitomo, H.1
Kato, R.2
Ito, A.3
Kasamatsu, S.4
Ikegami, Y.5
Kii, I.6
Kudos, A.7
Kobatake, E.8
Sumino, Y.9
Ishikawa, T.10
-
26
-
-
76749084410
-
A P-glycoprotein substrate transport assessed by comparing cellular and vesicular ATPase activity
-
Nervi P, Li-Blatter X, Aanismaa P. Seelig 2010.A P-glycoprotein substrate transport assessed by comparing cellular and vesicular ATPase activity. Biochim Biophys Acta 1798:515-525.
-
(2010)
Biochim Biophys Acta
, vol.1798
, pp. 515-525
-
-
Nervi, P.1
Li-Blatter, X.2
Seelig, A.P.3
-
27
-
-
73949111398
-
Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation 2010
-
Padowski JM, Pollack GM. Pharmacokinetic and pharmacodynamic implications of P-glycoprotein modulation 2010. Methods Mol Biol 596:359-384.
-
Methods Mol Biol
, vol.596
, pp. 359-384
-
-
Padowski, J.M.1
Pollack, G.M.2
-
29
-
-
32544451627
-
Reversal of MDR1/P-glycoprotein-mediated multidrug resistance by vector-based RNA interference in vitro and in vivo
-
Shi Z, Liang YJ, Chen ZS, Wang XW, Wang XH, Ding Y, Chen LM, Yang XP, Fu LW. 2006. Reversal of MDR1/P-glycoprotein-mediated multidrug resistance by vector-based RNA interference in vitro and in vivo. Cancer Biol Ther 5:39-47. (Pubitemid 43234976)
-
(2006)
Cancer Biology and Therapy
, vol.5
, Issue.1
, pp. 39-47
-
-
Shi, Z.1
Liang, Y.-J.2
Chen, Z.-S.3
Wang, X.-W.4
Wang, X.-H.5
Ding, Y.6
Chen, L.-M.7
Yang, X.-P.8
Fu, L.-W.9
-
30
-
-
36348967305
-
Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance
-
DOI 10.1158/0008-5472.CAN-07-2686
-
Shi Z, Peng XX, Kim IW, Shukla S, Si QS, Robey RW, Bates SE, Shen T, Ashby CR, Jr, Fu LW, Ambudkar SV, Chen ZS. 2007. Erlotinib (Tarceva, OSI-774) antagonizes ATP-binding cassette subfamily B member 1 and ATP-binding cassette subfamily G member 2-mediated drug resistance. Cancer Res 67: 11012-11020. (Pubitemid 350145931)
-
(2007)
Cancer Research
, vol.67
, Issue.22
, pp. 11012-11020
-
-
Shi, Z.1
Peng, X.-X.2
Kim, I.-W.3
Shukla, S.4
Si, Q.-S.5
Robey, R.W.6
Bates, S.E.7
Shen, T.8
Ashby Jr., C.R.9
Fu, L.-W.10
Ambudkar, S.V.11
Chen, Z.-S.12
-
31
-
-
54849439280
-
Chemical and pharmacological research of the plants in genus Euphorbia
-
Shi QW, Su XH, Kiyota H. 2008. Chemical and pharmacological research of the plants in genus Euphorbia. Chem Rev 108:4295-4327.
-
(2008)
Chem Rev
, vol.108
, pp. 4295-4327
-
-
Shi, Q.W.1
Su, X.H.2
Kiyota, H.3
-
32
-
-
69049090809
-
Cediranib (recentin, AZD2171) reverses ABCB1- And ABCC1-mediated multidrug resistance by inhibition of their transport function
-
Tao LY, Liang YJ, Wang F, Chen LM, Yan YY, Dai CL, Fu LW. 2009. Cediranib (recentin, AZD2171) reverses ABCB1- and ABCC1-mediated multidrug resistance by inhibition of their transport function. Cancer Chemother Pharmacol 64:961-969.
-
(2009)
Cancer Chemother Pharmacol
, vol.64
, pp. 961-969
-
-
Tao, L.Y.1
Liang, Y.J.2
Wang, F.3
Chen, L.M.4
Yan, Y.Y.5
Dai, C.L.6
Fu, L.W.7
-
33
-
-
42549160421
-
Anthracenedione derivative 1403P-3 induces apoptosis in KB and KBv200 cells via reactive oxygen species-independent mitochondrial pathway and death receptor pathway
-
Zhang JY, Wu HY, Xia XK, Liang YJ, Yan YY, She ZG, Lin YC, Fu LW. 2007. Anthracenedione derivative 1403P-3 induces apoptosis in KB and KBv200 cells via reactive oxygen species-independent mitochondrial pathway and death receptor pathway. Cancer Biol Ther 6:1413-1421.
-
(2007)
Cancer Biol Ther
, vol.6
, pp. 1413-1421
-
-
Zhang, J.Y.1
Wu, H.Y.2
Xia, X.K.3
Liang, Y.J.4
Yan, Y.Y.5
She, Z.G.6
Lin, Y.C.7
Fu, L.W.8
-
34
-
-
68449090917
-
Secalonic acid D induced leukemia cell apoptosis and cell cycle arrest of G(1) with involvement of GSK-3beta/beta-catenin/c-Myc pathway
-
Zhang JY, Tao LY, Liang YJ, Yan YY, Dai CL, Xia XK, She ZG, Lin YC, Fu LW. 2009. Secalonic acid D induced leukemia cell apoptosis and cell cycle arrest of G(1) with involvement of GSK-3beta/beta-catenin/c-Myc pathway. Cell Cycle 8:2444-2450.
-
(2009)
Cell Cycle
, vol.8
, pp. 2444-2450
-
-
Zhang, J.Y.1
Tao, L.Y.2
Liang, Y.J.3
Yan, Y.Y.4
Dai, C.L.5
Xia, X.K.6
She, Z.G.7
Lin, Y.C.8
Fu, L.W.9
-
35
-
-
77949404364
-
Assignments of 1H and 13C NMR signals of Euphorbia factor L1 and investigation of its anticancer activity in vitro
-
Zhang JY, Zhang C, Chen HB, Fu LW, Tao YW, Zheng XQ, Cao ZM, Zhong YF, Yu LH. 2010. Assignments of 1H and 13C NMR signals of Euphorbia factor L1 and investigation of its anticancer activity in vitro. J Med Plant Res 4:335-338.
-
(2010)
J Med Plant Res
, vol.4
, pp. 335-338
-
-
Zhang, J.Y.1
Zhang, C.2
Chen, H.B.3
Fu, L.W.4
Tao, Y.W.5
Zheng, X.Q.6
Cao, Z.M.7
Zhong, Y.F.8
Yu, L.H.9
-
36
-
-
65449152867
-
Vandetanib (Zactima, ZD6474) antagonizes ABCC1- And ABCG2-mediated multidrug resistance by inhibition of their transport function
-
Zheng LS, Wang F, Li YH, Zhang X, Chen LM, Liang YJ, Dai CL, Yan YY, Tao LY, Mi YJ, Yang AK, To KK, Fu LW. 2009. Vandetanib (Zactima, ZD6474) antagonizes ABCC1- and ABCG2-mediated multidrug resistance by inhibition of their transport function. PLoS One 4:e5172.
-
(2009)
PLoS One
, vol.4
-
-
Zheng, L.S.1
Wang, F.2
Li, Y.H.3
Zhang, X.4
Chen, L.M.5
Liang, Y.J.6
Dai, C.L.7
Yan, Y.Y.8
Tao, L.Y.9
Mi, Y.J.10
Yang, A.K.11
To, K.K.12
Fu, L.W.13
|