Anthracenedione derivative 1403P-3 induces apoptosis in KB and KBv200 cells via reactive oxygen species-independent mitochondrial pathway and death receptor pathway

Cancer Biology and Therapy

Volumn 6, Issue 9, 2007, Pages 1409-1417

  Zhang, Jian Ye ^a   Wu, Hai Ying ^a   Xia, Xue Kui ^a   Liang, Yong Ju ^a   Yan, Yan Yan ^a   She, Zhi Gang ^a   Lin, Yong Cheng ^a   Fu, Li Wu ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Anthracenedione derivative; Apoptosis; Bid; Caspases; Cytochrome c; KB cells; KBv200 cells; Multidrug resistance

Indexed keywords

1403P 3; 4 [5 (4 METHYL 1 PIPERAZINYL)[2,5' BI 1H BENZIMIDAZOL] 2' YL]PHENOL; ANTHRAQUINONE DERIVATIVE; BENZYLOXYCARBONYLISOLEUCYLGLUTAMYLTHREONYLASPARTYL FLUOROMETHYL KETONE; CASPASE 2; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 8 INHIBITOR; CASPASE 9; CYTOCHROME C; CYTOTOXIC AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; REACTIVE OXYGEN METABOLITE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN KB; CONTROLLED STUDY; CYTOTOXICITY; DNA BINDING; DNA FRAGMENTATION; DRUG STRUCTURE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IC 50; MITOCHONDRIAL MEMBRANE POTENTIAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA;

EID: 42549160421     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.6.9.4543     Document Type: Article

References (44)