Quantitative structure-property relationships for physiologically based pharmacokinetic modeling of volatile organic chemicals in rats

Toxicology and Applied Pharmacology

Volumn 189, Issue 3, 2003, Pages 221-232

  Béliveau, Martin ^a   Tardif, Robert ^a   Krishnan, Kannan ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

PBPK models; Pharmacokinetics; QSAR; VOCs

Indexed keywords

1,1 DICHLORO 2,2,2 TRIFLUOROETHANE; 1,1,1 TRICHLOROETHANE; 1,2,4 TRIMETHYLBENZENE; 1,3 DICHLOROPROPENE; ALKANE DERIVATIVE; AROMATIC HYDROCARBON; BENZENE DERIVATIVE; BROMINE; CARBON; CHLORINE; CHLOROFORM; CYTOCHROME P450 2E1; DICHLOROMETHANE; ETHYLBENZENE; ETHYLENE DERIVATIVE; HYDROGEN; TOLUENE; TRICHLOROETHYLENE; UNCLASSIFIED DRUG; VOLATILE ORGANIC COMPOUND;

ARTICLE; CALIBRATION; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; CONTROLLED STUDY; LIVER CLEARANCE; MEDICAL LITERATURE; MOLECULAR WEIGHT; NONHUMAN; PARTITION COEFFICIENT; PHYSIOLOGY; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RAT;

EID: 0038278532     PISSN: 0041008X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0041-008X(03)00129-7     Document Type: Article

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