Cell cycle-dependent induction of homologous recombination by a tightly regulated I-SceI fusion protein

PLoS ONE

Volumn 6, Issue 3, 2011, Pages

  Hartlerode, Andrea ^a   Odate, Shobu ^a,b   Shim, Inbo ^a,c   Brown, Jenifer ^a,d   Scully, Ralph ^a  

^a BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^b Department of Structural Biology   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; ESTROGEN RECEPTOR I SCEI FUSION PROTEIN; GENOMIC DNA; HYBRID PROTEIN; UNCLASSIFIED DRUG; DRUG DERIVATIVE; ESTROGEN RECEPTOR; GREEN FLUORESCENT PROTEIN; HYDROXYTAMOXIFEN; TAMOXIFEN; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE;

ARTICLE; BINDING SITE; CELL CYCLE G1 PHASE; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CELL DISRUPTION; CELLULAR DISTRIBUTION; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DNA REPAIR; DOUBLE STRANDED DNA BREAK; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME BINDING; GENE CONTROL; GENE DELETION; GENE DISRUPTION; HOMOLOGOUS RECOMBINATION; LIGAND BINDING; PROTEIN INDUCTION; STABLE EXPRESSION; CELL CYCLE; DRUG EFFECT; GENETIC RECOMBINATION; GENETICS; HUMAN; METABOLISM; TIME; TUMOR CELL LINE;

VERTEBRATA;

BRCA1 PROTEIN; CELL CYCLE; CELL LINE, TUMOR; CHROMOSOME BREAKAGE; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; ENZYME ACTIVATION; GREEN FLUORESCENT PROTEINS; HUMANS; RECEPTORS, ESTROGEN; RECOMBINANT FUSION PROTEINS; RECOMBINATION, GENETIC; S PHASE; TAMOXIFEN; TIME FACTORS;

EID: 79952415961     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0016501     Document Type: Article

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