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Volumn 41, Issue 3, 2005, Pages 99-109

Ligand-activated Flpe for temporally regulated gene modifications

Author keywords

Flpe; Induction; Recombinase; Tamoxifen

Indexed keywords

CRE RECOMBINASE; ESTROGEN RECEPTOR; FLIPPASE RECOMBINASE; GENE PRODUCT; HYBRID PROTEIN; LIGAND; STEROID RECEPTOR; TAMOXIFEN; UNCLASSIFIED DRUG;

EID: 17044404727     PISSN: 1526954X     EISSN: None     Source Type: Journal    
DOI: 10.1002/gene.20101     Document Type: Article
Times cited : (52)

References (36)
  • 1
    • 4043122029 scopus 로고    scopus 로고
    • Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning
    • Ahn S, Joyner AL. 2004. Dynamic changes in the response of cells to positive hedgehog signaling during mouse limb patterning. Cell 118:505-516.
    • (2004) Cell , vol.118 , pp. 505-516
    • Ahn, S.1    Joyner, A.L.2
  • 2
    • 0035185002 scopus 로고    scopus 로고
    • A FLP indicator strain, R26::FRAP, driving alkaline phosphatase expression from the ROSA26 locus
    • Awatramani R, Soriano P, Mai JJ, Dymecki SM. 2001. A FLP indicator strain, R26::FRAP, driving alkaline phosphatase expression from the ROSA26 locus. Nat Genet 29:257-259.
    • (2001) Nat Genet , vol.29 , pp. 257-259
    • Awatramani, R.1    Soriano, P.2    Mai, J.J.3    Dymecki, S.M.4
  • 3
    • 0041353550 scopus 로고    scopus 로고
    • Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation
    • Awatramani R, Soriano P, Rodriguez CI, Mai JJ, Dymecki SM. 2003. Cryptic boundaries in roof plate and choroid plexus identified by intersectional gene activation. Nat Genet 35:70-75.
    • (2003) Nat Genet , vol.35 , pp. 70-75
    • Awatramani, R.1    Soriano, P.2    Rodriguez, C.I.3    Mai, J.J.4    Dymecki, S.M.5
  • 4
    • 0031033948 scopus 로고    scopus 로고
    • The expression and function of Notch pathway genes in the developing rat eye
    • Bao ZZ, Cepko CL. 1997. The expression and function of Notch pathway genes in the developing rat eye. J Neurosci 17:1425-1434.
    • (1997) J Neurosci , vol.17 , pp. 1425-1434
    • Bao, Z.Z.1    Cepko, C.L.2
  • 5
    • 0027359404 scopus 로고
    • Isolation of Hsp90 mutants by screening for decreased steroid receptor function
    • Bohen SP, Yamamoto KR. 1993. Isolation of Hsp90 mutants by screening for decreased steroid receptor function. Proc Natl Acad Sci U S A 90:11424-11428.
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 11424-11428
    • Bohen, S.P.1    Yamamoto, K.R.2
  • 7
    • 0031874849 scopus 로고    scopus 로고
    • Improved properties of Flp recombinase evolved by cycling mutagenesis
    • Buchholz F, Angrand P-O, Stewart AF. 1998. Improved properties of Flp recombinase evolved by cycling mutagenesis. Nat Biotechnol 16:657-662.
    • (1998) Nat Biotechnol , vol.16 , pp. 657-662
    • Buchholz, F.1    Angrand, P.-O.2    Stewart, A.F.3
  • 8
    • 0027254748 scopus 로고
    • A 5′ element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila
    • Chung JH, Whitely M, Felsenfeld G. 1993. A 5′ element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila. Cell 74:505-514.
    • (1993) Cell , vol.74 , pp. 505-514
    • Chung, J.H.1    Whitely, M.2    Felsenfeld, G.3
  • 10
    • 0032481124 scopus 로고    scopus 로고
    • Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase
    • Danielian PS, Muccino D, Rowitch DH, Michael SK, McMahon AP. 1998. Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol 8:1323-1326.
    • (1998) Curr Biol , vol.8 , pp. 1323-1326
    • Danielian, P.S.1    Muccino, D.2    Rowitch, D.H.3    Michael, S.K.4    McMahon, A.P.5
  • 11
    • 0032169048 scopus 로고    scopus 로고
    • Using Flp-recombinase to characterize expansion of Wnt1-expressing neural progenitors in the mouse
    • Dymecki SM, Tomasiewicz H. 1998. Using Flp-recombinase to characterize expansion of Wnt1-expressing neural progenitors in the mouse. Dev Biol 201:57-65.
    • (1998) Dev Biol , vol.201 , pp. 57-65
    • Dymecki, S.M.1    Tomasiewicz, H.2
  • 13
    • 0028093078 scopus 로고
    • Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS
    • Echelard Y, Vassileva G, McMahon AP. 1994. Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS. Development 120:2213-2224.
    • (1994) Development , vol.120 , pp. 2213-2224
    • Echelard, Y.1    Vassileva, G.2    McMahon, A.P.3
  • 15
    • 0031589555 scopus 로고    scopus 로고
    • Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains
    • Feil R, Wagner J, Metzger D, Chambon P. 1997. Regulation of Cre recombinase activity by mutated estrogen receptor ligand-binding domains. Biochem Res Commun 237:752-757.
    • (1997) Biochem Res Commun , vol.237 , pp. 752-757
    • Feil, R.1    Wagner, J.2    Metzger, D.3    Chambon, P.4
  • 16
    • 0036164048 scopus 로고    scopus 로고
    • A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action
    • Guo C, Yang W, Lobe CG. 2002. A Cre recombinase transgene with mosaic, widespread tamoxifen-inducible action. genesis 32:8-18.
    • (2002) Genesis , vol.32 , pp. 8-18
    • Guo, C.1    Yang, W.2    Lobe, C.G.3
  • 17
    • 0037090881 scopus 로고    scopus 로고
    • Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: A tool for temporally regulated gene activation/inactivation in the mouse
    • Hayashi S, McMahon AP 2002. Efficient recombination in diverse tissues by a tamoxifen-inducible form of Cre: a tool for temporally regulated gene activation/inactivation in the mouse. Dev Biol 244(2):305-18.
    • (2002) Dev Biol , vol.244 , Issue.2 , pp. 305-318
    • Hayashi, S.1    McMahon, A.P.2
  • 19
    • 0035793045 scopus 로고    scopus 로고
    • Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (CreERT2) in adipocytes
    • Imai T, Jiang M, Chambon P. 2001. Impaired adipogenesis and lipolysis in the mouse upon selective ablation of the retinoid X receptor alpha mediated by a tamoxifen-inducible chimeric Cre recombinase (CreERT2) in adipocytes. Proc Natl Acad Sci U S A 98:224-228.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 224-228
    • Imai, T.1    Jiang, M.2    Chambon, P.3
  • 20
    • 0033571243 scopus 로고    scopus 로고
    • Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: Comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases
    • Indra AK, Warot X, Brocard J, Bornert JM, Xiao JH, Chambon P, Metzger D. 1999. Temporally-controlled site-specific mutagenesis in the basal layer of the epidermis: comparison of the recombinase activity of the tamoxifen-inducible Cre-ER(T) and Cre-ER(T2) recombinases. Nucleic Acids Res 27:4324-4327.
    • (1999) Nucleic Acids Res , vol.27 , pp. 4324-4327
    • Indra, A.K.1    Warot, X.2    Brocard, J.3    Bornert, J.M.4    Xiao, J.H.5    Chambon, P.6    Metzger, D.7
  • 23
    • 0029043630 scopus 로고
    • Ligand-regulated site-specific recombination
    • Logie C, Stewart AF. 1995. Ligand-regulated site-specific recombination. Proc Natl Acad Sci U S A 92:5940-5944.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 5940-5944
    • Logie, C.1    Stewart, A.F.2
  • 24
    • 0032230285 scopus 로고    scopus 로고
    • Positive and negative discrimination of estrogen receptor agonists and antagonists using site-specific DNA recombinase fusion proteins
    • Logie C, Nichols M, Myles K, Funder JW, Stewart AF. 1998. Positive and negative discrimination of estrogen receptor agonists and antagonists using site-specific DNA recombinase fusion proteins. Mol Endocrinol 12:1120-1132.
    • (1998) Mol Endocrinol , vol.12 , pp. 1120-1132
    • Logie, C.1    Nichols, M.2    Myles, K.3    Funder, J.W.4    Stewart, A.F.5
  • 25
    • 0029164598 scopus 로고
    • Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase
    • Metzger D, Clifford J, Chiba H, Chambon P 1995. Conditional site-specific recombination in mammalian cells using a ligand-dependent chimeric Cre recombinase. Proc Natl Acad Sci U S A 92:6991-6995.
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 6991-6995
    • Metzger, D.1    Clifford, J.2    Chiba, H.3    Chambon, P.4
  • 26
    • 0025884056 scopus 로고
    • Efficient selection for high-expression transfectants with a novel eukaryotic vector
    • Niwa H, Yamamura K, Miyazaki J. 1991. Efficient selection for high-expression transfectants with a novel eukaryotic vector. Gene 108:193-200.
    • (1991) Gene , vol.108 , pp. 193-200
    • Niwa, H.1    Yamamura, K.2    Miyazaki, J.3
  • 28
    • 0027760995 scopus 로고
    • Sonic hedgehog mediates the polarizing activity of the ZPA
    • Riddle RD, Johnson RL, Laufer E, Tabin C. 1993. Sonic hedgehog mediates the polarizing activity of the ZPA. Cell 75:1425-1434.
    • (1993) Cell , vol.75 , pp. 1425-1434
    • Riddle, R.D.1    Johnson, R.L.2    Laufer, E.3    Tabin, C.4
  • 30
    • 0027256152 scopus 로고
    • Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90
    • Scherrer LC, Picard D, Massa E, Harmon JM, Simons SJ, Yamamoto KR, Pratt WB. 1993. Evidence that the hormone binding domain of steroid receptors confers hormonal control on chimeric proteins by determining their hormone-regulated binding to heat-shock protein 90. Biochemistry 32:5381-5386.
    • (1993) Biochemistry , vol.32 , pp. 5381-5386
    • Scherrer, L.C.1    Picard, D.2    Massa, E.3    Harmon, J.M.4    Simons, S.J.5    Yamamoto, K.R.6    Pratt, W.B.7
  • 33
    • 0001244671 scopus 로고
    • Whole mount in situ hybridization of vertebrate embryos
    • Oxford: IRL Press
    • Wilkinson DG. 1992. Whole mount in situ hybridization of vertebrate embryos. In: In situ hybridization: a practical approach. Oxford: IRL Press. p 74-83.
    • (1992) In Situ Hybridization: A Practical Approach , pp. 74-83
    • Wilkinson, D.G.1
  • 34
    • 0030990991 scopus 로고    scopus 로고
    • Disruption of overlapping transcripts in the ROSA beta geo 26 trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells
    • Zambrowicz BP, Imamoto A, Fiering S, Herzenberg LA, Kerr WG, Soriano P. 1997. Disruption of overlapping transcripts in the ROSA beta geo 26 trap strain leads to widespread expression of beta-galactosidase in mouse embryos and hematopoietic cells. Proc Natl Acad Sci U S A 94:3789-3794.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 3789-3794
    • Zambrowicz, B.P.1    Imamoto, A.2    Fiering, S.3    Herzenberg, L.A.4    Kerr, W.G.5    Soriano, P.6
  • 35
    • 4043064327 scopus 로고    scopus 로고
    • Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1
    • Zervas M, Millet S, Ahn S, Joyner AL. 2004. Cell behaviors and genetic lineages of the mesencephalon and rhombomere 1. Neuron 43:345-357.
    • (2004) Neuron , vol.43 , pp. 345-357
    • Zervas, M.1    Millet, S.2    Ahn, S.3    Joyner, A.L.4
  • 36
    • 0037062516 scopus 로고    scopus 로고
    • Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate
    • Zirlinger M, Lo L, McMahon AP, Anderson DJ. 2002. Transient expression of the bHLH factor neurogenin-2 marks a subpopulation of neural crest cells biased for a sensory but not a neuronal fate. Proc Natl Acad Sci U S A 99:8084-8089.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 8084-8089
    • Zirlinger, M.1    Lo, L.2    McMahon, A.P.3    Anderson, D.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.