Increased whole-body and sustained liver cortisol regeneration by 11β-hydroxysteroid dehydrogenase type 1 in obese men with type 2 diabetes provides a target for enzyme inhibition

Diabetes

Volumn 60, Issue 3, 2011, Pages 720-725

  Stimson, Roland H ^a   Andrew, Ruth ^a   McAvoy, Norma C ^b   Tripathi, Dhiraj ^b   Hayes, Peter C ^b   Walker, Brian R ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; DEXAMETHASONE; HYDROCORTISONE; TRACER;

ADIPOSE TISSUE; ADULT; AGED; ARTERIAL BLOOD; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ENZYME INHIBITION; HEPATIC VEIN; HUMAN; HYDROCORTISONE BLOOD LEVEL; LIVER LEVEL; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SPLANCHNIC BLOOD FLOW; STEADY STATE; TISSUE LEVEL; TREATMENT RESPONSE; WHOLE BODY SCINTISCANNING;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ADULT; AGED; ANALYSIS OF VARIANCE; BODY COMPOSITION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; DEXAMETHASONE; DIABETES MELLITUS, TYPE 2; GLUCOCORTICOIDS; HUMANS; HYDROCORTISONE; LIVER; MALE; MIDDLE AGED; OBESITY; TANDEM MASS SPECTROMETRY;

EID: 79952392526     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db10-0726     Document Type: Article

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