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Volumn 89, Issue 9, 2004, Pages 4755-4761

11β-hydroxysteroid dehydrogenase type 1 activity in lean and obese males with type 2 diabetes mellitus

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; CHOLESTEROL; CORTISONE; GLUCOCORTICOID; HYDROCORTISONE; ISOENZYME; TETRAHYDROCORTISOL; TETRAHYDROCORTISONE;

EID: 4544263736     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2003-032240     Document Type: Article
Times cited : (142)

References (45)
  • 1
    • 0034119138 scopus 로고    scopus 로고
    • The perils of portliness: Causes and consequences of visceral adiposity
    • Montague CT, O'Rahilly S 2000 The perils of portliness: causes and consequences of visceral adiposity. Diabetes 49:883-888
    • (2000) Diabetes , vol.49 , pp. 883-888
    • Montague, C.T.1    O'Rahilly, S.2
  • 3
    • 0033038329 scopus 로고    scopus 로고
    • Insulin sensitivity in subjects with type 2 diabetes. Relationship to cardiovascular risk factors: The Insulin Resistance Atherosclerosis Study
    • Haffner SM, D'Agostino Jr R, Mykkanen L, Tracy R, Howard B, Rewers M, Selby J, Savage PJ, Saad MF 1999 Insulin sensitivity in subjects with type 2 diabetes. Relationship to cardiovascular risk factors: the Insulin Resistance Atherosclerosis Study. Diabetes Care 22:562-568
    • (1999) Diabetes Care , vol.22 , pp. 562-568
    • Haffner, S.M.1    D'Agostino Jr., R.2    Mykkanen, L.3    Tracy, R.4    Howard, B.5    Rewers, M.6    Selby, J.7    Savage, P.J.8    Saad, M.F.9
  • 4
    • 0032587240 scopus 로고    scopus 로고
    • The role of TNFα and TNF receptors in obesity and insulin resistance
    • Hotamisligil GS 1999 The role of TNFα and TNF receptors in obesity and insulin resistance. J Intern Med 245:621-625
    • (1999) J Intern Med , vol.245 , pp. 621-625
    • Hotamisligil, G.S.1
  • 7
    • 0036134187 scopus 로고    scopus 로고
    • Resistin and obesity-associated insulin resistance
    • Steppan CM, Lazar MA 2002 Resistin and obesity-associated insulin resistance. Trends Endocrinol Metab 13:18-23
    • (2002) Trends Endocrinol Metab , vol.13 , pp. 18-23
    • Steppan, C.M.1    Lazar, M.A.2
  • 8
    • 0035488931 scopus 로고    scopus 로고
    • The relation of markers of inflammation to the development of glucose disorders in the elderly: The Cardiovascular Health Study
    • Barzilay JI, Abraham L, Heckbert SR, Cushman M, Kuller LH, Resnick HE, Tracy RP 2001 The relation of markers of inflammation to the development of glucose disorders in the elderly: the Cardiovascular Health Study. Diabetes 50:2384-2389
    • (2001) Diabetes , vol.50 , pp. 2384-2389
    • Barzilay, J.I.1    Abraham, L.2    Heckbert, S.R.3    Cushman, M.4    Kuller, L.H.5    Resnick, H.E.6    Tracy, R.P.7
  • 9
    • 1642467862 scopus 로고    scopus 로고
    • Decreased serum levels of adiponectin are a risk factor for the progression to type 2 diabetes in the Japanese population: The Funagata study
    • Daimon M, Oizumi T, Saitoh T, Kameda W, Hirata A, Yamaguchi H, Ohnuma H, Igarashi M, Tominaga M, Kato T 2003 Decreased serum levels of adiponectin are a risk factor for the progression to type 2 diabetes in the Japanese population: the Funagata study. Diabetes Care 26:2015-2020
    • (2003) Diabetes Care , vol.26 , pp. 2015-2020
    • Daimon, M.1    Oizumi, T.2    Saitoh, T.3    Kameda, W.4    Hirata, A.5    Yamaguchi, H.6    Ohnuma, H.7    Igarashi, M.8    Tominaga, M.9    Kato, T.10
  • 10
    • 0023695231 scopus 로고
    • Abdominal obesity and the development of noninsulin-dependent diabetes mellitus
    • Bjorntorp P 1988 Abdominal obesity and the development of noninsulin-dependent diabetes mellitus. Diabetes Metab Rev 4:615-622
    • (1988) Diabetes Metab Rev , vol.4 , pp. 615-622
    • Bjorntorp, P.1
  • 11
    • 0027503864 scopus 로고
    • Altered adrenocorticotropin and Cortisol secretion in abdominal obesity: Implications for the insulin resistance syndrome
    • Hautanen A, Adlercreutz H 1993 Altered adrenocorticotropin and Cortisol secretion in abdominal obesity: implications for the insulin resistance syndrome. J Intern Med 234:461-469
    • (1993) J Intern Med , vol.234 , pp. 461-469
    • Hautanen, A.1    Adlercreutz, H.2
  • 12
    • 0026095840 scopus 로고
    • The human gene for 11β-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization
    • Tannin GM, Agarwal AK, Monder C, New MI, White PC 1991 The human gene for 11β-hydroxysteroid dehydrogenase. Structure, tissue distribution, and chromosomal localization. J Biol Chem 266:16653-16658
    • (1991) J Biol Chem , vol.266 , pp. 16653-16658
    • Tannin, G.M.1    Agarwal, A.K.2    Monder, C.3    New, M.I.4    White, P.C.5
  • 13
    • 0028034209 scopus 로고
    • Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme
    • Albiston AL, Obeyesekere VR, Smith RE, Krozowski ZS 1994 Cloning and tissue distribution of the human 11β-hydroxysteroid dehydrogenase type 2 enzyme. Mol Cell Endocrinol 105:R11-R17
    • (1994) Mol Cell Endocrinol , vol.105
    • Albiston, A.L.1    Obeyesekere, V.R.2    Smith, R.E.3    Krozowski, Z.S.4
  • 14
    • 0031046241 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess
    • White PC, Mune T, Agarwal AK 1997 11β-Hydroxysteroid dehydrogenase and the syndrome of apparent mineralocorticoid excess. Endocr Rev 18:135-156
    • (1997) Endocr Rev , vol.18 , pp. 135-156
    • White, P.C.1    Mune, T.2    Agarwal, A.K.3
  • 15
    • 0030936556 scopus 로고    scopus 로고
    • Does central obesity reflect "Cushing's disease of the omentum"?
    • Bujalska IJ, Kumar S, Stewart PM 1997 Does central obesity reflect "Cushing's disease of the omentum"? Lancet 349:1210-1213
    • (1997) Lancet , vol.349 , pp. 1210-1213
    • Bujalska, I.J.1    Kumar, S.2    Stewart, P.M.3
  • 19
    • 0032990860 scopus 로고    scopus 로고
    • Cortisol metabolism in human obesity: Impaired cortisone→cortisol conversion in subjects with central adiposity
    • Stewart PM, Boulton A, Kumar S, Clark PM, Shackleton CH 1999 Cortisol metabolism in human obesity: impaired cortisone→cortisol conversion in subjects with central adiposity. J Clin Endocrinol Metab 84:1022-1027
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 1022-1027
    • Stewart, P.M.1    Boulton, A.2    Kumar, S.3    Clark, P.M.4    Shackleton, C.H.5
  • 21
    • 0026089570 scopus 로고
    • Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians
    • McKeigue PM, Shah B, Marmot MG 1991 Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians. Lancet 337:382-386
    • (1991) Lancet , vol.337 , pp. 382-386
    • McKeigue, P.M.1    Shah, B.2    Marmot, M.G.3
  • 22
    • 0031596094 scopus 로고    scopus 로고
    • 11β-Hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction
    • Shams M, Kilby MD, Somerset DA, Howie A, Gupta A, Wood PJ, Afnan M, Stewart PM 1998 11β-Hydroxysteroid dehydrogenase type 2 in human pregnancy and reduced expression in intrauterine growth restriction. Hum Reprod 13:799-804
    • (1998) Hum Reprod , vol.13 , pp. 799-804
    • Shams, M.1    Kilby, M.D.2    Somerset, D.A.3    Howie, A.4    Gupta, A.5    Wood, P.J.6    Afnan, M.7    Stewart, P.M.8
  • 23
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC 1985 Homeostasis model assessment: insulin resistance and β-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412-419
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 24
    • 0027414682 scopus 로고
    • Mass spectrometry in the diagnosis of steroid-related disorders and hypertension research
    • Shackleton CHL 1993 Mass spectrometry in the diagnosis of steroid-related disorders and hypertension research. J Steroid Biochem Mol Biol 45:127-140
    • (1993) J Steroid Biochem Mol Biol , vol.45 , pp. 127-140
    • Shackleton, C.H.L.1
  • 25
    • 0029847585 scopus 로고    scopus 로고
    • Urinary free cortisone and the assessment of 11β-hydroxysteroid dehydrogenase activity in man
    • Oxf
    • Palermo M, Shackleton CH, Mantero F, Stewart PM 1996 Urinary free cortisone and the assessment of 11β-hydroxysteroid dehydrogenase activity in man. Clin Endocrinol (Oxf) 45:605-611
    • (1996) Clin Endocrinol , vol.45 , pp. 605-611
    • Palermo, M.1    Shackleton, C.H.2    Mantero, F.3    Stewart, P.M.4
  • 26
    • 0000934190 scopus 로고
    • Study of adrenocortical function in obesity
    • Migeon CJ, Green OC, Eckert JP 1963 Study of adrenocortical function in obesity. Metabolism 12:718-739
    • (1963) Metabolism , vol.12 , pp. 718-739
    • Migeon, C.J.1    Green, O.C.2    Eckert, J.P.3
  • 28
    • 0034797813 scopus 로고    scopus 로고
    • Fat distribution in obese women is associated with subtle alterations of the hypothalamic-pituitary-adrenal axis activity and sensitivity to glucocorticoids
    • Oxf
    • Duclos M, Gatta B, Corcuff JB, Rashedi M, Pehourcq F, Roger P 2001 Fat distribution in obese women is associated with subtle alterations of the hypothalamic-pituitary-adrenal axis activity and sensitivity to glucocorticoids. Clin Endocrinol (Oxf) 55:447-454
    • (2001) Clin Endocrinol , vol.55 , pp. 447-454
    • Duclos, M.1    Gatta, B.2    Corcuff, J.B.3    Rashedi, M.4    Pehourcq, F.5    Roger, P.6
  • 29
    • 0027162106 scopus 로고
    • Hyperactivity of the hypothalamo-pituitary-adrenal axis in obesity: A study of ACTH, AVP, β-lipotrophin and cortisol responses to insulin-induced hypoglycaemia
    • Oxf
    • Weaver JU, Kopelman PG, McLoughlin L, Forsling ML, Grossman A 1993 Hyperactivity of the hypothalamo-pituitary-adrenal axis in obesity: a study of ACTH, AVP, β-lipotrophin and cortisol responses to insulin-induced hypoglycaemia. Clin Endocrinol (Oxf) 39:345-350
    • (1993) Clin Endocrinol , vol.39 , pp. 345-350
    • Weaver, J.U.1    Kopelman, P.G.2    McLoughlin, L.3    Forsling, M.L.4    Grossman, A.5
  • 30
    • 0033305631 scopus 로고    scopus 로고
    • Differentiation of adipose stromal cells: The roles of glucocorticoids and 11β-hydroxysteroid dehydrogenase
    • Bujalska IJ, Kumar S, Hewison M, Stewart PM 1999 Differentiation of adipose stromal cells: the roles of glucocorticoids and 11β-hydroxysteroid dehydrogenase. Endocrinology 140:3188-3196
    • (1999) Endocrinology , vol.140 , pp. 3188-3196
    • Bujalska, I.J.1    Kumar, S.2    Hewison, M.3    Stewart, P.M.4
  • 31
    • 0036959901 scopus 로고    scopus 로고
    • A "switch" in dehydrogenase to reductase activity of 11β-hydroxysteroid dehydrogenase type 1 and differentiation of human adipose stromal cells
    • Bujalska IJ, Hewison M, Stewart PM 2002 A "switch" in dehydrogenase to reductase activity of 11β-hydroxysteroid dehydrogenase type 1 and differentiation of human adipose stromal cells. J Clin Endocrinol Metab 87:1205-1210
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1205-1210
    • Bujalska, I.J.1    Hewison, M.2    Stewart, P.M.3
  • 32
    • 0036882136 scopus 로고    scopus 로고
    • Expression of 11β-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity
    • Tomlinson JW, Sinha B, Bujalska I, Hewison M, Stewart PM 2002 Expression of 11β-hydroxysteroid dehydrogenase type 1 in adipose tissue is not increased in human obesity. J Clin Endocrinol Metab 87:5630-5635
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5630-5635
    • Tomlinson, J.W.1    Sinha, B.2    Bujalska, I.3    Hewison, M.4    Stewart, P.M.5
  • 33
    • 0037902924 scopus 로고    scopus 로고
    • Subcutaneous adipose 11β-hydroxysteroid dehydrogenase type 1 activity and messenger ribonucleic acid levels are associated with adiposity and insulinemia in Pima Indians and Caucasians
    • Lindsay RS, Wake DJ, Nair S, Bunt J, Livingstone DE, Permana PA, Tataranni PA, Walker BR 2003 Subcutaneous adipose 11β-hydroxysteroid dehydrogenase type 1 activity and messenger ribonucleic acid levels are associated with adiposity and insulinemia in Pima Indians and Caucasians. J Clin Endocrinol Metab 88:2738-2744
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 2738-2744
    • Lindsay, R.S.1    Wake, D.J.2    Nair, S.3    Bunt, J.4    Livingstone, D.E.5    Permana, P.A.6    Tataranni, P.A.7    Walker, B.R.8
  • 34
    • 0036324073 scopus 로고    scopus 로고
    • Tissue-specific changes in peripheral cortisol metabolism in obese women: Increased adipose 11β-hydroxysteroid dehydrogenase type 1 activity
    • Rask E, Walker BR, Soderberg S, Livingstone DE, Eliasson M, Johnson O, Andrew R, Olsson T 2002 Tissue-specific changes in peripheral cortisol metabolism in obese women: increased adipose 11β-hydroxysteroid dehydrogenase type 1 activity. J Clin Endocrinol Metab 87:3330-3336
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 3330-3336
    • Rask, E.1    Walker, B.R.2    Soderberg, S.3    Livingstone, D.E.4    Eliasson, M.5    Johnson, O.6    Andrew, R.7    Olsson, T.8
  • 35
    • 0036075081 scopus 로고    scopus 로고
    • Expression of the mRNA coding for 11β-hydroxysteroid dehydrogenase type 1 in adipose tissue from obese patients: An in situ hybridization study
    • Paulmyer-Lacroix O, Boullu S, Oliver C, Alessi MC, Grino M 2002 Expression of the mRNA coding for 11β-hydroxysteroid dehydrogenase type 1 in adipose tissue from obese patients: an in situ hybridization study. J Clin Endocrinol Metab 87:2701-2705
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 2701-2705
    • Paulmyer-Lacroix, O.1    Boullu, S.2    Oliver, C.3    Alessi, M.C.4    Grino, M.5
  • 39
    • 0026051922 scopus 로고
    • Regulation of 11β-hydroxysteroid dehydrogenase activity in human skin fibroblasts: Enzymatic modulation of glucocorticoid action
    • Hammami MM, Siiteri PK 1991 Regulation of 11β-hydroxysteroid dehydrogenase activity in human skin fibroblasts: enzymatic modulation of glucocorticoid action. J Clin Endocrinol Metab 73:326-334
    • (1991) J Clin Endocrinol Metab , vol.73 , pp. 326-334
    • Hammami, M.M.1    Siiteri, P.K.2
  • 40
    • 0034099201 scopus 로고    scopus 로고
    • Lack of relationship between 11β-hydroxysteroid dehydrogenase setpoint and insulin sensitivity in the basal state and after 24 h of insulin infusion in healthy subjects and type 2 diabetic patients
    • Oxf
    • Kerstens MN, Riemens SC, Sluiter WJ, Pratt JJ, Wollhers BG, Dullaart RP 2000 Lack of relationship between 11β-hydroxysteroid dehydrogenase setpoint and insulin sensitivity in the basal state and after 24 h of insulin infusion in healthy subjects and type 2 diabetic patients. Clin Endocrinol (Oxf) 52:403-411
    • (2000) Clin Endocrinol , vol.52 , pp. 403-411
    • Kerstens, M.N.1    Riemens, S.C.2    Sluiter, W.J.3    Pratt, J.J.4    Wollhers, B.G.5    Dullaart, R.P.6
  • 41
    • 0036925387 scopus 로고    scopus 로고
    • Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance
    • Andrews RC, Herlihy O, Livingstone DE, Andrew R, Walker BR 2002 Abnormal cortisol metabolism and tissue sensitivity to cortisol in patients with glucose intolerance. J Clin Endocrinol Metab 87:5587-5593
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 5587-5593
    • Andrews, R.C.1    Herlihy, O.2    Livingstone, D.E.3    Andrew, R.4    Walker, B.R.5
  • 42
    • 10744221420 scopus 로고    scopus 로고
    • Body fat distribution and cortisol metabolism in healthy men: Enhanced 5β-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver
    • Westerbacka J, Yki-Jarvinen H, Vehkavaara S, Hakkinen AM, Andrew R, Wake DJ, Seckl JR, Walker BR 2003 Body fat distribution and cortisol metabolism in healthy men: enhanced 5β-reductase and lower cortisol/cortisone metabolite ratios in men with fatty liver. J Clin Endocrinol Metab 88:4924-4931
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 4924-4931
    • Westerbacka, J.1    Yki-Jarvinen, H.2    Vehkavaara, S.3    Hakkinen, A.M.4    Andrew, R.5    Wake, D.J.6    Seckl, J.R.7    Walker, B.R.8
  • 44
    • 0028839840 scopus 로고
    • Carbenoxolone increases hepatic insulin sensitivity in man: A novel role for 11-oxosteroid reductase in enhancing glucocorticoid receptor activation
    • Walker BR, Connacher AA, Lindsay RM, Webb DJ, Edwards CR 1995 Carbenoxolone increases hepatic insulin sensitivity in man: a novel role for 11-oxosteroid reductase in enhancing glucocorticoid receptor activation. J Clin Endocrinol Metab 80:3155-3159
    • (1995) J Clin Endocrinol Metab , vol.80 , pp. 3155-3159
    • Walker, B.R.1    Connacher, A.A.2    Lindsay, R.M.3    Webb, D.J.4    Edwards, C.R.5
  • 45
    • 0037238379 scopus 로고    scopus 로고
    • Effects of the 11β-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes
    • Andrews RC, Rooyackers O, Walker BR 2003 Effects of the 11β-hydroxysteroid dehydrogenase inhibitor carbenoxolone on insulin sensitivity in men with type 2 diabetes. J Clin Endocrinol Metab 88:285-291
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 285-291
    • Andrews, R.C.1    Rooyackers, O.2    Walker, B.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.