Chronic escitalopram treatment restores spatial learning, monoamine levels, and hippocampal long-term potentiation in an animal model of depression

Psychopharmacology

Volumn 214, Issue 2, 2011, Pages 477-494

  Bhagya, V ^a   Srikumar, B N ^a,b   Raju, T R ^a   Shankaranarayana Rao, B S ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH AND NEUROSCIENCES   (India)

^b University of Bordeaux   (France)

Author keywords

Cognitive deficits; Endogenous depression; Escitalopram; Long term potentiation; Radial arm maze; Serotonergic dysfunction

Indexed keywords

ACETYLCHOLINESTERASE; CLOMIPRAMINE; DOPAMINE; ESCITALOPRAM; MONOAMINE; NORADRENALIN; SEROTONIN; SUCROSE;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN STEM; CONTROLLED STUDY; CORPUS STRIATUM; DEPRESSION; DRUG EFFICACY; ENZYME ACTIVITY; FORCED SWIMMING TEST; FRONTAL CORTEX; HIPPOCAMPUS; HYPOTHALAMUS; LEARNING; LONG TERM CARE; LONG TERM POTENTIATION; MAZE TEST; MEMORY CONSOLIDATION; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPSE; TASK PERFORMANCE; TREATMENT DURATION; WORKING MEMORY;

ACETYLCHOLINESTERASE; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BIOGENIC MONOAMINES; CITALOPRAM; CLOMIPRAMINE; DEPRESSION; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; FOOD HABITS; HIPPOCAMPUS; LEARNING; LONG-TERM POTENTIATION; MALE; MAZE LEARNING; MEMORY; MOTOR ACTIVITY; RATS; RATS, WISTAR; SEROTONIN UPTAKE INHIBITORS; SWIMMING; TIME FACTORS;

EID: 79952282453     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-010-2054-x     Document Type: Article

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