Hyperactivity of hypothalamic pituitary axis in neonatal clomipramine model of depression

Journal of Neural Transmission

Volumn 105, Issue 10-12, 1998, Pages 1335-1339

  Prathiba, J ^a   Kumar, K B ^a   Karanth, K S ^a  

^a KASTURBA MEDICAL COLLEGE   (India)

Author keywords

Corticosterone levels; Dexamethasone suppression; Neonatal clomipramine; REM sleep deprivation

Indexed keywords

CLOMIPRAMINE; CORTICOSTERONE; DEXAMETHASONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DEPRESSION; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MALE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; REM SLEEP DEPRIVATION; SUBCUTANEOUS DRUG ADMINISTRATION;

ANIMALS; ANIMALS, NEWBORN; CLOMIPRAMINE; DEPRESSION; DEPRESSION, CHEMICAL; DEXAMETHASONE; DISEASE MODELS, ANIMAL; GLUCOCORTICOIDS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; RATS; RATS, WISTAR; SECRETORY RATE; SLEEP, REM;

EID: 0032418121     PISSN: 03009564     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007020050135     Document Type: Article

References (16)

1. Asnis GM, Halbreich U, Sachar EJ, Swaminathan R, Ostrow LC, Novacenko H, Davis M, Endicott J, Puig-Antich J (1983) Plasma cortisol secretion and REM period latency in adult endogenous depression. Am J Psychiatry 140: 750-752
2. Greden JF, Gardner R, King D, Grunhaus L, Carroll BJ, Kronfol Z (1983) Dexamethasone suppression tests in antidepressant treatment of melancholia. Arch Gen Psychiatry 40: 493-500
3. Greenberg L, Edwards E, Henn FA (1989) Dexamethasone suppression test in helpless rats. Biol Psychiatry 26: 530-532
4. Hartley P, Neill D, Hagler M, Kors D, Vogel G (1990) Procedure and age-dependent hyperactivity in a new animal model of endogenous depression. Neurosci Biobehav Rev 14:69-72
5. Mattingly D (1962) A simple fluorimetric method for the estimation of free 11-hydroxy corticoids in human plasma. J Clin Pathol 15: 374-379
6. Neill D, Vogel G, Hagler M, Kors D, Hennessey A (1990) Diminished sexual activity in a new animal model of endogenous depression. Neurosci Biobehav Rev 14: 73-76
7. Prathiba J, Kumar KB, Karanth KS (1995) Effects of neonatal clomipramine on cholinergic receptor sensitivity and passive avoidance behavior in adult rats. J Neural Transm 100: 93-99
8. Shiromani PJ, Gillin JC, Henrisken SJ (1987) Acetylcholine and the regulation of REM sleep: basic mechanisms and clinical implications for affective illness and narcolepsy. Ann Rev Pharmacol Toxicol 27: 137-156
9. Smotherman WP, Hunt LE, McGinnis LM, Levine S (1979) Motherinfant separation in group living rhesus macaques: a hormonal analysis. Dev Psychobiol 12: 211-217
10. Steiner SS, Eliman SJ (1972) Relation between REM sleep and intracranial self stimulation. Science 177: 112-1124
11. Van Riezen H, Schmieden H, Wren A (1976) Behavioral changes following olfactory bulbectomy in rat: a possible model for the detection of antidepressant drugs. Br J Pharmacol 52: 426-427
12. Vogel G, Hartley P, Neill D, Hagler M, Kors D (1988) Animal depression moel by neonatal clomipramine: Reduction of shock induced aggression. Pharmacol Biochem Behav 31: 103-106
13. Vogel G, Neill D, Hagler M, Kors D (1990a) A new animal model of endogenous depression: a summary of present findings. Neurosci Biobehav Rev 14: 85-91
14. Vogel G, Neill D, Hagler M, Kors D, Hartley P (1990b) Decreased intracranial self stimulatiuon in a new animal model of endogenous depression. Neurosci Biobehav Rev 14: 65-68
15. Vogel G, Neill D, Kors D, Hagler M (1990c) REM sleep abnormalities in a new animal model of endogenous depression. Neurosci Biobehav Rev 14: 77-83
16. Willner P (1985) Depression: a psychobiological synthesis. Wiley, New York