Chronic treatment with the antidepressant amitriptyline prevents impairments in water maze learning in aging rats

Journal of Neuroscience

Volumn 22, Issue 4, 2002, Pages 1436-1442

  Yau, Joyce L W ^a   Noble, June ^b   Hibberd, Carina ^c   Rowe, Wayne B ^a   Meaney, Michael J ^a   Morris, Richard G M ^b   Seckl, Jonathan R ^c  

^a WESTERN GENERAL HOSPITAL   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Amitriptyline; Anxiety; Corticosterone; Glucocorticoid; Spatial learning; Water maze

Indexed keywords

AMITRIPTYLINE; ANTIDEPRESSANT AGENT; CORTICOSTERONE; GLUCOCORTICOID;

AGED; AGING; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CHRONOPHARMACOLOGY; COGNITIVE DEFECT; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; FEEDBACK SYSTEM; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; LEARNING; LONG TERM EXPOSURE; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; PSYCHOPHARMACOLOGY; RAT; TASK PERFORMANCE;

EID: 0037083649     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-04-01436.2002     Document Type: Article

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