Properties of human and rabbit cytosolic serine hydroxymethyltransferase are changed by single nucleotide polymorphic mutations

Archives of Biochemistry and Biophysics

Volumn 442, Issue 1, 2005, Pages 92-101

  Fu, Tzu Fun ^a   Hunt, Sharyn ^b   Schirch, Verne ^b   Safo, Martin K ^b   Chen, Bing Hung ^a,c  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

B6 enzyme; Folate binding affinity; Folic acid; Gene polymorphism; Homocysteine; One carbon metabolism; Serine hydroxymethyltransferase; Single nucleotide polymorphism; Site directed mutagenesis; Tetrahydrofolate

Indexed keywords

5 FORMYLTETRAHYDROPTEROYL PENTAGLUTAMATE; 5,10 METHENYLTETRAHYDROPTEROYL PENTAGLUTAMATE; ASPARAGINE; COMPLEMENTARY DNA; ENZYME; GLUTAMIC ACID DERIVATIVE; GLYCINE; GLYCINE HYDROXYMETHYLTRANSFERASE; LEUCINE; PHENYLALANINE; PYRIDOXAL 5 PHOSPHATE; SERINE; TETRAHYDROFOLIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DISSOCIATION CONSTANT; ENZYME CHEMISTRY; ENZYME STABILITY; ENZYME STRUCTURE; ESCHERICHIA COLI; GENE EXPRESSION SYSTEM; MUTAGENESIS; MUTANT; MUTATIONAL ANALYSIS; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MODIFICATION; PROTEIN PURIFICATION; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE;

ANIMALS; APOENZYMES; CYTOSOL; DNA, COMPLEMENTARY; GLYCINE HYDROXYMETHYLTRANSFERASE; HOLOENZYMES; HUMANS; KINETICS; LIGANDS; MOLECULAR STRUCTURE; MUTATION; NUCLEOTIDES; POLYMORPHISM, SINGLE NUCLEOTIDE; PTEROYLPOLYGLUTAMIC ACIDS; PYRIDOXAL PHOSPHATE; RABBITS; SPECIES SPECIFICITY; TETRAHYDROFOLATES;

ESCHERICHIA COLI; ORYCTOLAGUS CUNICULUS;

EID: 25144475606     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.abb.2005.07.018     Document Type: Article

References (59)

1. E.M. Balk, J. Lau, L.C. Goudas, H.S. Jordan, B. Kupelnick, L.U. Kim, and R.H. Karas Ann. Intern. Med. 139 2003 670 682
2. P. Frosst, H.J. Blom, R. Milos, P. Goyette, C.A. Sheppard, R.G. Matthews, G.J. Boers, H.M. den, L.A. Kluijtmans, and L.P. van den Heuvel Nat. Genet. 10 1995 111 113
3. R. Maas, and R.H. Boger Atheroscler. Suppl 4 2003 5 17
4. A. Loktionov J. Nutr. Biochem. 14 2003 426 451
5. J.L. Gueant, R.M. Gueant-Rodriguez, G. Anello, P. Bosco, L. Brunaud, C. Romano, R. Ferri, A. Romano, M. Candito, and B. Namour Clin. Chem. Lab Med. 41 2003 1473 1477
6. G. D'Aniello, P. Florio, L. Sabatini, F.M. Severi, D. Fineschi, G. Cito, C.G. Guidoni, and F. Petraglia J. Hypertens. 21 2003 1915 1920
7. K.J. Lievers, L.A. Kluijtmans, and H.J. Blom Ann. Clin. Biochem. 40 2003 46 59
8. S. Girgis, I.M. Nasrallah, J.R. Suh, E. Oppenheim, K.A. Zanetti, M.G. Mastri, and P.J. Stover Gene 210 1998 315 324
9. P.J. Stover, L.H. Chen, J.R. Suh, D.M. Stover, K. Keyomarsi, and B. Shane J. Biol. Chem. 272 1997 1842 1848
10. M.R. Narkewicz, S.D. Sauls, S.S. Tjoa, C. Teng, and P.V. Fennessey Biochem. J. 313 Pt 3 1996 991 996
11. T.F. Fu, J.P. Rife, and V. Schirch Arch. Biochem. Biophys. 393 2001 42 50
12. J.F. Gregory III, G.J. Cuskelly, B. Shane, J.P. Toth, T.G. Baumgartner, and P.W. Stacpoole Am. J. Clin. Nutr. 72 2000 1535 1541
13. P. Stover, and V. Schirch J. Biol. Chem. 265 1990 14227 14233
14. P. Stover, and V. Schirch Biochemistry 31 1992 2155 2164
15. P. Stover, and V. Schirch J. Biol. Chem. 266 1991 1543 1550
16. P. Stover, H. Kruschwitz, and V. Schirch Adv. Exp. Med. Biol. 338 1993 679 685
17. S. Girgis, J.R. Suh, J. Jolivet, and P.J. Stover J. Biol. Chem. 272 1997 4729 4734
18. S.B. Renwick, K. Snell, and U. Baumann Structure 6 1998 1105 1116
19. V. Trivedi, A. Gupta, V.R. Jala, P. Saravanan, G.S. Rao, N.A. Rao, H.S. Savithri, and H.S. Subramanya J. Biol. Chem. 277 2002 17161 17169
20. D.M. Szebenyi, X. Liu, I.A. Kriksunov, P.J. Stover, and D.J. Thiel Biochemistry 39 2000 13313 13323
21. J.N. Scarsdale, S. Radaev, G. Kazanina, V. Schirch, and H.T. Wright J. Mol. Biol. 296 2000 155 168
22. J.N. Scarsdale, G. Kazanina, S. Radaev, V. Schirch, and H.T. Wright Biochemistry 38 1999 8347 8358
23. N.V. Grishin, M.A. Phillips, and E.J. Goldsmith Protein Sci. 4 1995 1291 1304
24. F.W. Alexander, E. Sandmeier, P.K. Mehta, and P. Christen Eur. J. Biochem. 219 1994 953 960
25. S. Chaturvedi, and V. Bhakuni J. Biol. Chem. 278 2003 40793 40805
26. K.A. Zanetti, and P.J. Stover J. Biol. Chem. 278 2003 10142 10149
27. S.G. Heil, N.M. Van der Put, E.T. Waas, H.M. den, F.J. Trijbels, and H.J. Blom Mol. Genet. Metab 73 2001 164 172
28. A. Hishida, K. Matsuo, N. Hamajima, H. Ito, M. Ogura, Y. Kagami, H. Taji, Y. Morishima, N. Emi, and K. Tajima Haematologica 88 2003 159 166
29. C.L. Relton, C.S. Wilding, M.S. Pearce, A.J. Laffling, P.A. Jonas, S.A. Lynch, E.J. Tawn, and J. Burn J. Med. Genet. 41 2004 256 260
30. C.L. Relton, C.S. Wilding, A.J. Laffling, P.A. Jonas, T. Burgess, K. Binks, E.J. Tawn, and J. Burn Mol. Genet. Metab 81 2004 273 281
31. C.F. Skibola, M.T. Smith, A. Hubbard, B. Shane, A.C. Roberts, G.R. Law, S. Rollinson, E. Roman, R.A. Cartwright, and G.J. Morgan Blood 99 2002 3786 3791
32. T.F. Fu, S.M. di, and V. Schirch Anal. Biochem. 290 2001 359 365
33. H. Kruschwitz, S. Ren, S.M. Di, and V. Schirch Protein Expr. Purif. 6 1995 411 416
34. M.L. di Salvo, F.S. Delle, B.D. De, F. Bossa, and V. Schirch Protein Expr. Purif. 13 1998 177 183
35. T.F. Fu, E.S. Boja, M.K. Safo, and V. Schirch J. Biol. Chem. 278 2003 31088 31094
36. T.F. Fu, J.N. Scarsdale, G. Kazanina, V. Schirch, and H.T. Wright J. Biol. Chem. 278 2003 2645 2653
37. V. Schirch, K. Shostak, M. Zamora, and M. Guatam-Basak J. Biol. Chem. 266 1991 759 764
38. L.V. Schirch, C.M. Tatum Jr., and S.J. Benkovic Biochemistry 16 1977 410 419
39. M.S. Chen, and L.V. Schirch J. Biol. Chem. 248 1973 7979 7984
40. D.M. Szebenyi, F.N. Musayev, M.L. di Salvo, M.K. Safo, and V. Schirch Biochemistry 43 2004 6865 6876
41. V. Schirch, S. Hopkins, E. Villar, and S. Angelaccio J. Bacteriol. 163 1985 1 7
42. L. Schirch, and M. Ropp Biochemistry 6 1967 253 257
43. L. Schirch, and T. Gross J. Biol. Chem. 243 1968 5651 5655
44. M.C. Anguera, J.R. Suh, H. Ghandour, I.M. Nasrallah, J. Selhub, and P.J. Stover J. Biol. Chem. 278 2003 29856 29862
45. H.L. Kruschwitz, D. McDonald, E.A. Cossins, and V. Schirch J. Biol. Chem. 269 1994 28757 28763
46. W.B. Holmes, and D.R. Appling J. Biol. Chem. 277 2002 20205 20213
47. M.H. Cordes, N.P. Walsh, C.J. McKnight, and R.T. Sauer Science 284 1999 325 328
48. M.H. Cordes, R.E. Burton, N.P. Walsh, C.J. McKnight, and R.t. Sauer Nat. Struct. Biol. 7 2000 1129 1132
49. A. Witte, G. Schrot, P. Schon, and W. Lubitz Mol. Microbiol. 26 1997 337 346
50. K. Yamada, Z. Chen, R. Rozen, and R.G. Matthews Proc. Natl. Acad. Sci. USA 98 2001 14853 14858
51. R.G. Matthews, C. Sheppard, and C. Goulding Eur. J. Pediatr. 157 Suppl. 2 1998 S54 S59
52. J. Sumner, D.A. Jencks, S. Khani, and R.G. Matthews J. Biol. Chem. 261 1986 7697 7700
53. S. Gulati, P. Baker, Y.N. Li, B. Fowler, W. Kruger, L.C. Brody, and R. Banerjee Hum. Mol. Genet. 5 1996 1859 1865
54. T.H. Rod, J.L. Radkiewicz, and C.L. Brooks III Proc. Natl. Acad. Sci. USA 100 2003 6980 6985
55. P.T. Rajagopalan, S. Lutz, and S.J. Benkovic Biochemistry 41 2002 12618 12628
56. J. Chen, C. Kyte, M. Valcin, W. Chan, J.G. Wetmur, J. Selhub, D.J. Hunter, and J. Ma Int. J. Cancer 110 2004 617 620
57. C.F. Skibola, M.S. Forrest, F. Coppede, L. Agana, A. Hubbard, M.T. Smith, P.M. Bracci, and E.A. Holly Blood 104 2004 2155 2162
58. J.B. Scheer, A.D. Mackey, and J.F. Gregory III J. Nutr. 135 2005 233 238
59. F. Martini, S. Angelaccio, S. Pascarella, D. Barra, F. Bossa, and V. Schirch J. Biol. Chem. 262 1987 5499 5509