Genetic polymorphisms in folate and alcohol metabolism and breast cancer risk: A case-control study in Thai women

Breast Cancer Research and Treatment

Volumn 123, Issue 3, 2010, Pages 885-893

  Sangrajrang, Suleeporn ^a   Sato, Yasunori ^b   Sakamoto, Hiromi ^b   Ohnami, Sumiko ^b   Khuhaprema, Thiravud ^a   Yoshida, Teruhiko ^b  

^a NATIONAL CANCER INSTITUTE   (Thailand)

^b NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Alcohol; Breast cancer; Folate; Metabolizing enzyme; Single nucleotide polymorphisms

Indexed keywords

5,10 METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); ALCOHOL; CYTOCHROME P450 2E1; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; FOLIC ACID; GLUTATHIONE TRANSFERASE P1; METHIONINE SYNTHASE; METHIONINE SYNTHASE REDUCTASE; SEROTONIN TRANSPORTER; ARYLAMINE ACETYLTRANSFERASE; DRD3 PROTEIN, HUMAN; FERREDOXIN NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE REDUCTASE; NAT2 PROTEIN, HUMAN; SLC6A4 PROTEIN, HUMAN;

ADH1C GENE; ADULT; ALCOHOL CONSUMPTION; ALCOHOL METABOLISM; ALDH2 GENE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; CYP2E1 GENE; DRD2 GENE; DRD3 GENE; FEMALE; FOLATE METABOLISM; GENE; GENE INTERACTION; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; GSTP1 GENE; HOMOZYGOTE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MENOPAUSE; MTHFR GENE; MTR GENE; MTRR GENE; NAT1 GENE; NAT2 GENE; POSTMENOPAUSE; PREMENOPAUSE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SLC6A4 GENE; THAILAND; TYMS GENE; BIOTRANSFORMATION; BREAST TUMOR; DRINKING BEHAVIOR; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MIDDLE AGED; PHENOTYPE; RISK; RISK ASSESSMENT; RISK FACTOR; STATISTICAL MODEL;

ADULT; ALCOHOL DRINKING; ARYLAMINE N-ACETYLTRANSFERASE; BIOTRANSFORMATION; BREAST NEOPLASMS; CASE-CONTROL STUDIES; ETHANOL; FEMALE; FERREDOXIN-NADP REDUCTASE; FOLIC ACID; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LOGISTIC MODELS; MIDDLE AGED; ODDS RATIO; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, DOPAMINE D2; RECEPTORS, DOPAMINE D3; RISK ASSESSMENT; RISK FACTORS; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; THAILAND;

EID: 79952114981     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-010-0804-4     Document Type: Article

References (36)

1. Sriplung H, Sontipong S, Martin N, Wiangnon S, Vootiprux V, Cheirsilpa A, Kanchanabat C, Khuhaprema T (2005) Cancer incidence in Thailand, 1995-1997. Asian Pac J Cancer Prev 6(3):276-281
2. Stover PJ (2004) Physiology of folate and vitamin B12 in health and disease. Nutr Rev 62(6Pt2):S3-S12
3. Kim YI (1999) Folate and carcinogenesis: evidence, mechanisms and implications. J Nutr Biochem 10(2):66-88
4. Longnecker MP (1994) Alcoholic beverage consumption in relation to risk of breast cancer: meta-Analysis and review. Cancer Causes Control 5(1):73-82 (Pubitemid 24066596)
5. Smith-Warner SA, Spiegelman D, Yaun SS, van den Brandt PA, Folsom AR, Goldbohm RA, Graham S, Holmberg L, Howe GR, Marshall JR, Miller AB, Potter JD, Speizer FE, Willett WC, Wolk A, Hunter DJ (1998) Alcohol and breast cancer in women: A pooled analysis of cohort studies. JAMA 279(7):535-540 (Pubitemid 28113433)
6. Singletary KW, Gapstur SM (2001) Alcohol and breast cancer: review of epidemiologic and experimental evidence and potential mechanisms. JAMA 286(17):2143-2151 (Pubitemid 34044116)
7. Purohit V (1998) Moderate alcohol consumption and estrogen levels in postmenopausal women: A review. Alcohol Clin Exp Res 22(5):994-997 (Pubitemid 28408990)
8. Thomas DB (1995) Alcohol as a cause of cancer. Environ Health Perspect 103(Suppl. 8):153-160 (Pubitemid 26040892)
9. Feron VJ, Til HP, de Vrijer F, Woutersen RA, Cassee FR, van Bladeren PJ (1991) Aldehydes: occurrence, carcinogenic potential, mechanism of action and risk assessment. Mutat Res 259(3-4):363-385
10. Halsted CH, Villanueva JA, Devlin AM, Chandler CJ (2002) Metabolic interactions of alcohol and folate. J Nutr 132(Suppl. 8):2367S-2372S (Pubitemid 34848109)
11. Zhang S, Willett WC, Selhub J, Hunter DJ, Giovannucci EL, Holmes MD, Colditz GA, Hankinson SE (2003) Plasma folate, vitamin B6, vitamin B12, homocysteine, and risk of breast cancer. J Natl Cancer Inst 95(5):373-380 (Pubitemid 36395257)
12. Rohan TE, Jain MG, Howe GR, Miller AB (2000) Dietary folate consumption and breast cancer risk. J Natl Cancer Inst 92(3):266-269 (Pubitemid 30099787)
13. Sellers TA, Kushi LH, Cerhan JR, Vierkant RA, Gapstur SM, Vachon CM, Olson JE, Therneau TM, Folsom AR (2001) Dietary folate intake, alcohol, and risk of breast cancer in a prospective study of postmenopausal women. Epidemiology 12(4):420-428 (Pubitemid 32566484)
14. Negri E, La Vecchia C, Franceschi S (2000) Re: dietary folate consumption and breast cancer risk. J Natl Cancer Inst 92(15):1270-1271 (Pubitemid 30627736)
15. Yoshimura K, Hanaoka T, Ohnami S, Ohnami S, Kohno T, Liu Y, Yoshida T, Sakamoto H, Tsugane S (2003) Allele frequencies of single nucleotide polymorphisms (SNPs) in 40 candidate genes for gene-environment studies on cancer: data from populationbased Japanese random samples. J Hum Genet 48(12):654-658 (Pubitemid 38031310)
16. Ergul E, Sazci A, Utkan Z, Canturk NZ (2003) Polymorphisms in the MTHFR gene are associated with breast cancer. Tumor Biol 24(6):286-290 (Pubitemid 38327990)
17. Semenza JC, Delfino RJ, Ziogas A, Anton-Culver H (2003) Breast cancer risk and methylenetetrahydrofolate reductase polymorphism. Breast Cancer Res Treat 77(3):217-223 (Pubitemid 36197636)
18. Gershoni-Baruch R, Dagan E, Israeli D, Kasinetz L, Kadouri E, Friedman E (2000) Association of the C677T polymorphism in the MTHFR gene with breast and/or ovarian cancer risk in Jewish women. Eur J Cancer 36(18):2313-2316
19. Yu CP, Wu MH, Chou YC, Yang T, You SL, Chen CJ, Sun CA (2007) Breast cancer risk associated with multigenotypic polymorphisms in folate-metabolizing genes: A nested case-control study in Taiwan. Anticancer Res 27(3B):1727-1732 (Pubitemid 46807266)
20. Le Marchand L, Haiman CA, Wilkens LR, Kolonel LN, Henderson BE (2004) MTHFR polymorphisms, diet, HRT, and breast cancer risk: the multiethnic cohort study. Cancer Epidemiol Biomarkers Prev 13(12):2071-2077 (Pubitemid 40054300)
21. Sharp L, Little J, Schofield AC, Pavlidou E, Cotton SC, Miedzybrodzka Z, Baird JO, Haites NE, Heys SD, Grubb DA (2002) Folate and breast cancer: the role of polymorphisms in methylenetetrahydrofolate reductase (MTHFR). Cancer Lett 181(1):65-71 (Pubitemid 34310663)
22. Linnebank M, Schmidt S, Kölsch H, Linnebank A, Heun R, Schmidt-Wolf IG, Glasmacher A, Fliessbach K, Klockgether T, Schlegel U, Pels H (2004) The methionine synthase polymorphism D919G alters susceptibility to primary central nervous system lymphoma. Br J Cancer 90(10):1969-1971 (Pubitemid 38746338)
23. Lu CM, Chung MC, Huang CH, Ko YC (2005) Interaction effect in bladder cancer between N-Acetyltransferase 2 genotype and alcohol drinking. Urol Int 75(4):360-364
24. Rodrigo L, Alvarez V, Rodriguez M, Pérez R, Alvarez R, Coto E (1999) N-Acetyltransferase-2, glutathione S-Transferase M1, alcohol dehydrogenase, and cytochrome P450IIE1 genotypes in alcoholic liver cirrhosis: A case-control study. Scand J Gastroenterol 34(3):303-307 (Pubitemid 29193004)
25. Hamajima N, Hirose K, Tajima K et al (2002) Alcohol, tobacco and breast cancer-collaborative reanalysis of individual data from 53 epidemiological studies, including 58, 515 women with breast cancer and 95, 067 women without the disease. Br J Cancer 87(11):1234-1245
26. Bowlin SJ, Leske MC, Varma A, Nasca P, Weinstein A, Caplan L (1997) Breast cancer risk and alcohol consumption: results from a large case-control study. Int J Epidemiol 26(5):915-923 (Pubitemid 27478505)
27. Brodie MS, Shefner SA, Dunmiddie TV (1990) Ethanol increases the firing rate of dopamine neurons of the rat ventral tegmental area in vitro. Brain Res 508(1):65-69 (Pubitemid 20042066)
28. Brodie MS (2002) Increased ethanol excitation of dopaminergic neurons of the ventral tegmental area after chronic ethanol treatment. Alcohol Clin Exp Res 26(7):1024-1030 (Pubitemid 34778780)
29. McBride WJ, Chernet E, Dyr W, Lumeng L, Li TK (1993) Densities of dopamine D2 receptors are reduced in CNS regions of alcohol-preferring P rats. Alcohol 10(5):387-390 (Pubitemid 23276856)
30. Stefanini E, Frau M, Garau MG, Garau B, Fadda F, Gessa GL (1992) Alcohol-preferring rats have fewer dopamine D2 receptors in the limbic system. Alcohol Alcohol 27(2):127-130
31. Noble EP, Blum K, Ritchie T, Montgomery A, Sheridan PJ (1991) Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism. Arch Gen Psychiatry 48(7):648-654
32. Reich T, Hinrichs A, Culverhouse R, Bierut L (1999) Genetic studies of alcoholism and substance dependence. Am J Hum Genet 65(3):599-605 (Pubitemid 30468703)
33. Blum K, Noble EP, Sheridan PJ, Montgomery A, Ritchie T, Jagadeeswaran P, Nogami H, Briggs AH, Cohn JB (1990) Allelic association of human dopamine D2 receptor gene in alcoholism. JAMA 263(15):2055-2060 (Pubitemid 20139952)
34. Bolos AM, Dean M, Lucas-Derse S, Ramsburg M, Brown GL, Goldman D (1990) Population and pedigree studies reveal a lack of association between the dopamine D2 receptor gene and alcoholism. JAMA 264(24):3156-3160
35. Huang SY, Lin WW, Ko HC, Lee JF, Wang TJ, Chou YH, Yin SJ, Lu RB (2004) Possible interaction of alcohol dehydrogenase and aldehyde dehydrogenase genes with the dopamine D2 receptor gene in anxiety-depressive alcohol dependence. Alcohol Clin Exp Res 28(3):374-384
36. Philibert RA, Sandhu H, Hollenbeck N, Gunter T, Adams W, Madan A (2008) The relationship of 5HTT (SLC6A4) methylation and genotype on mRNA expression and liability to major depression and alcohol dependence in subjects from the Iowa Adoption Studies. Am J Med Genet B 147B(5):543-549 (Pubitemid 351961655)