Increased bioavailability of tricin-amino acid derivatives via a prodrug approach

Journal of Medicinal Chemistry

Volumn 54, Issue 5, 2011, Pages 1529-1536

  Ninomiya, Masayuki ^a   Tanaka, Kaori ^a   Tsuchida, Yuzo ^b   Muto, Yoshinori ^a   Koketsu, Mamoru ^a   Watanabe, Kunitomo ^a  

^a GIFU UNIVERSITY   (Japan)

^b Hououdou Co Ltd   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

4',5,7 TRIHYDROXY 3',5' DIMETHOXYFLAVONE; FLAVONE DERIVATIVE; PRODRUG; QUERCETIN; QUERCETIN ALANINE GLUTAMIC ACID; TRICIN ALANINE; TRICIN ALANINE ASPARTIC ACID; TRICIN ALANINE GLUTAMIC ACID; TRICIN AMINO ACID DERIVATIVE; TRICIN ASPARTIC ACID; TRICIN GLUTAMIC ACID; TRICIN GLYCINE; TRICIN PHENYLALANINE; TRICIN VALINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG STABILITY; DRUG SYNTHESIS; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; RAT; SINGLE DRUG DOSE;

ADMINISTRATION, ORAL; ALANINE; ANIMALS; ANTIVIRAL AGENTS; BIOLOGICAL AVAILABILITY; CELL LINE; CELL MEMBRANE PERMEABILITY; CYTOMEGALOVIRUS; DOGS; DRUG STABILITY; FLAVONOIDS; GLUTAMIC ACID; MALE; PRODRUGS; RATS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 79952272904     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm1015457     Document Type: Article

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