How to make drugs orally active: A substrate template for peptide transporter PePT1

Angewandte Chemie - International Edition

Volumn 39, Issue 3, 2000, Pages 505-508

  Bailey, Patrick D ^a   Boyd, C A Richard ^b   Bronk, J Ramsey ^c   Collier, Ian D ^a   Meredith, David ^b   Morgan, Keith M ^a   Temple, Catherine S ^b  

^a HERIOT WATT UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF YORK   (United Kingdom)

Author keywords

Drug research; Molecular modeling; Molecular recognition; Peptides; Structure activity relationships

Indexed keywords

AMINO ACID DERIVATIVE; ANILIDE; BETA AMINO ACID; BETA LACTAM DERIVATIVE; CARRIER PROTEIN; DIPEPTIDE; MEMBRANE PROTEIN; PROTEIN PEPT1; TRIPEPTIDE; UNCLASSIFIED DRUG;

ALKYLATION; ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG TRANSPORT; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR MODEL; MOLECULAR RECOGNITION; NONHUMAN; RAT; SMALL INTESTINE; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; XENOPUS LAEVIS;

EID: 0034603011     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1521-3773(20000204)39:3<505::aid-anie505>3.0.co;2-b     Document Type: Article

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