Flavonoids from Artemisia copa with anti-inflammatory activity

Planta Medica

Volumn 72, Issue 1, 2006, Pages 72-74

  Moscatelli, Valeria ^a,c   Hnatyszyn, Oksana ^a   Acevedo, Cristina ^a   Megías, Javier ^b   Alcaraz, María José ^b   Ferraro, Graciela ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

^b UNIVERSITY OF VALENCIA   (Spain)

^c Faculty of Pharmacy   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ANTIINFLAMMATORY AGENT; ARTEMISIA COPA EXTRACT; AXILLARIN; CHRYSOERIOL; CYCLOOXYGENASE 2; DICHLOROMETHANE; FLAVONOID; INDOMETACIN; JACEOSIDIN; LIPOPOLYSACCHARIDE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; NITRIC OXIDE; PENDULETIN; PHOSPHOLIPASE A2; PLANT EXTRACT; PROSTAGLANDIN E2; SCALARADIAL; SPINACETIN; TRICIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIINFLAMMATORY ACTIVITY; ARTEMISIA; ARTEMISIA COPA; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ISOLATION; DRUG MECHANISM; ENZYME INHIBITION; FRACTIONATION; IC 50; MACROPHAGE; MOUSE; NONHUMAN; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTEMISIA; CELL LINE; CYCLOOXYGENASE 2; FLAVONOIDS; MICE; MOLECULAR STRUCTURE; PHOSPHOLIPASES A;

ANIMALIA; ARTEMISIA; ARTEMISIA COPA;

EID: 32644450768     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2005-873177     Document Type: Article

References (15)

1. Ratera EL, Ratera MO. Plantas de la Flora Argentina empleadas en Medicina Popular. Buenos Aires: Editorial Hemisferio Sur, 1980: p. 108
2. Giberti G. Herbal folk medicine in Northwestern Argentina: Compositae. J Ethnopharmacol 1983; 7: 321-41
3. Quarenghi de Riera MV, Catalan CN, Israilev LRA, Seeligmann P. Flavonoides foliares de Artemisia copa (Compositae). Bol Soc Argent Bot 1991; 27: 253-5
4. Miño J, Moscatelli V, Hnatyszyn O, Gorzalczany S, Acevedo C, Ferraro G. Antinociceptive and anti-inflammatory activities of Artemisia copa extracts. Pharmacol Res 2004; 50: 59-63
5. Vane JR, Mitchell JA, Appleton I, Tomlison A, Bishop-Bailey D, Croxtall J et al. Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proc Natl Acad Sci USA 1994; 91: 2046-50
6. Liu XH, Kirschenbaum A, Yao S, Lee R, Holland JF, Levine AC. Inhibition of cyclooxygenase-2 suppresses angiogenesis and the growth of prostate cancer in vivo. J Urol 2000; 164: 820-5
7. Warner TD, Giuliano F, Vojnovic I, Bukasa A, Mitchell JA, Vane JR. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: a full in vitro analysis. Proc Natl Acad Sci USA 1999; 96: 7563-8
8. Justice E, Carruthers DM. Cardiovascular risk and COX-2 inhibition in rheumatological practice. J Hum Hypertens 2005; 19: 1-5
9. Schinella GR, Giner RM, Recio MC, Mordujovich DB, Rios JL, Manez S. Anti-inflammatory effects of South American Tanacetum vulgare. J Pharm Pharmacol 1998; 50: 1069-74
10. Mishra B, Priyadarsini KI, Kumar MS, Unnikrishnan MK, Mohan H. Effect of O-glycosylation on the antioxidant activity and free radical reactions of a plant flavonoid, chrysoeriol. Bioorg Med Chem 2003; 11: 2677-85
11. Kwon YS, Kim CM. Antioxidant constituents from the stem of Sorghum bicolor. Arch Pharm Res 2003; 26: 535-9
12. Kim SR, Park MJ, Lee MK, Sung SH, Park EJ, Kim J et al. Flavonoids of Inula britannica protect cultured cortical cells from necrotic cell death induced by glutamate. Free Radic Biol Med 2002; 32: 596-604
13. Lee HG, Yu KA, Oh WK, Baeg TW, Oh HC, Ahn JS et al. Inhibitory effect of jaceosidin isolated from Artemisia argyi on the function of E6 and E7 oncoproteins of HPV 16. J Ethnopharmacol 2005; 98: 339-43
14. Misko TP, Schilling RJ, Salvemini D, Moore WM, Currie MG. A fluorometric assay for the measurement of nitrite in biological samples. Anal Biochem 1993; 214: 11-6
15. García Pastor P, De Rosa S, De Giulio A, Paya M, Alcaraz MJ. Modulation of acute and chronic inflammatory processes by cacospongionolide B, a novel inhibitor of human synovial phospholipase A2. Br J Pharmacol 1999; 126: 301-11