Tissue distribution in mice and metabolism in murine and human liver of apigenin and tricin, flavones with putative cancer chemopreventive properties

Cancer Chemotherapy and Pharmacology

Volumn 60, Issue 2, 2007, Pages 257-266

  Cai, Hong ^a   Boocock, David J ^a   Steward, William P ^a   Gescher, Andreas J ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

Chemoprevention; Flavonoids; Metabolism

Indexed keywords

ADENOSINE 3' PHOSPHATE 5' PHOSPHOSULFATE; APIGENIN; BETA GLUCURONIDASE; FLAVONE; SULFATE; TRICIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHEMOPROPHYLAXIS; COLORECTAL ADENOMA; CONTROLLED STUDY; CYTOSOL; DIETARY INTAKE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG METABOLISM; ENZYME METABOLISM; GASTROINTESTINAL MUCOSA; GLUCURONIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; IN VITRO STUDY; LIVER METABOLISM; LIVER MICROSOME; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SULFONATION; TISSUE DISTRIBUTION; ULTRAVIOLET RADIATION;

ANIMALS; ANTINEOPLASTIC AGENTS; APIGENIN; CHEMOPREVENTION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOSOL; FLAVONOIDS; HUMANS; INTESTINAL MUCOSA; MICE; MICE, INBRED C57BL; MICROSOMES, LIVER; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TISSUE DISTRIBUTION;

EID: 34248350462     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-006-0368-5     Document Type: Article

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