Hepatic deletion of Smad7 in mouse leads to spontaneous liver dysfunction and aggravates alcoholic liver injury

PLoS ONE

Volumn 6, Issue 2, 2011, Pages

  Zhu, Lu ^a   Wang, Lingdi ^a   Wang, Xiao ^a   Luo, Xiaolin ^a   Yang, Ling ^a   Zhang, Rui ^a   Yin, Hongkun ^a   Xie, Dong ^a   Pan, Yi ^a   Chen, Yan ^a  

^a UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CRE RECOMBINASE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMAD7 PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; SMAD7 PROTEIN, MOUSE;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL LIVER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL MOTILITY; CONTROLLED STUDY; DISEASE EXACERBATION; EPITHELIAL MESENCHYMAL TRANSITION; GENE DELETION; IMMUNOHISTOCHEMISTRY; LIPOGENESIS; LIVER CELL; LIVER DYSFUNCTION; LIVER FUNCTION; MALE; MOUSE; NONHUMAN; OVERALL SURVIVAL; PATHOGENESIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; ANTIBODY SPECIFICITY; CELL CULTURE; DISEASE COURSE; GENETICS; LIVER; LIVER DISEASE; LIVER FUNCTION TEST; METABOLISM; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE;

MUS;

ANIMALS; CELLS, CULTURED; DISEASE PROGRESSION; GENE DELETION; HEPATOCYTES; LIVER; LIVER DISEASES; LIVER DISEASES, ALCOHOLIC; LIVER FUNCTION TESTS; MALE; MICE; MICE, TRANSGENIC; ORGAN SPECIFICITY; SMAD7 PROTEIN;

EID: 79952254584     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0017415     Document Type: Article

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