Helicobacter pylori induces macrophage apoptosis by activation of arginase II

Journal of Immunology

Volumn 168, Issue 9, 2002, Pages 4692-4700

  Gobert, Alain P ^a   Cheng, Yulan ^a   Wang, Jian Ying ^a   Boucher, Jean Luc ^a   Iyer, Ramaswamy K ^a   Cederbaum, Stephen D ^a   Casero Jr , Robert A ^a   Newton, Jamie C ^a   Wilson, Keith T ^a  

^a UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGINASE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ENTERITIS; ENZYME ACTIVATION; GASTRITIS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; MACROPHAGE; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL;

EID: 0036570172     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.168.9.4692     Document Type: Article

References (63)

1. Decreased prevalence of Helicobacter pylori infection in gastroesophageal reflux disease
2. Lymphocytes in the human gastric mucosa during Helicobacter pylori have a T helper cell 1 phenotype
3. Epithelial cytotoxicity, immune responses, and inflammatory components of Helicobacter pylori gastritis
4. Helicobacter pylori stimulates inducible nitric oxide synthase expression and activity in a murine macrophage cell line
5. Increased expression and cellular localization of inducible nitric oxide synthase and cyclooxygenase 2 in Helicobacter pylori gastritis
6. Soluble surface proteins from Helicobacter pylori activate monocytes/macrophages by lipopolysaccharide-independent mechanism
7. + Helicobacter pylori strains
8. The effect of class II major histocompatibility complex expression on adherence of Helicobacter pylori and induction of apoptosis in gastric epithelial cells: A mechanism for T helper cell type 1-mediated damage
9. Surface proteins from Helicobacter pylori exhibit chemotactic activity for human leukocytes and are present in gastric mucosa
10. Interleukin 1 is processed and released during apoptosis
11. Nitric oxide-mediated apoptosis in murine peritoneal macrophages
12. Co- induction of arginase and nitric oxide synthase in murine macrophages activated by lipopolysaccharide
13. Nitric oxide biosynthesis, nitric oxide synthase inhibitors and arginase competition for L-arginine utilization
14. L-arginine availability modulates local nitric oxide production and parasite killing in experimental trypanosomiasis
15. Helicobacter pylori arginase inhibits nitric oxide production by eukaryotic cells: A strategy for bacterial survival
16. Arginase II downregulates nitric oxide (NO) production and prevents NO-mediated apoptosis in murine macrophage-derived RAW 264.7 cells
17. Spermine inhibits proinflammatory cytokine synthesis in human mononuclear cells: A counterregulatory mechanism that restrains the immune response
18. 2+-RhoA signaling pathway required for polyamine-dependent intestinal epithelial cell migration
19. Polyamine depletion stabilizes p53 resulting in inhibition of normal intestinal epithelial cell proliferation
20. Involvement of polyamines in apoptosis: Facts and controversies: Effectors or protectors?
21. ω-hydroxynor-L-arginine
22. A standardized mouse model of Helicobacter pylori infection: Introducing the Sydney strain
23. Murine macrophages use oxygen- and nitric oxide-dependent mechanisms to synthesize S-nitroso-albumin and to kill extracellular trypanosomes
24. Suppression of in vitro cytotoxic response by macrophages due to induced arginase
25. Increased expression of inducible nitric oxide synthase and cyclooxygenase-2 in Barrett's esophagus and associated adenocarcinomas
26. Promoter methylation regulates Helicobacter pyloristimulated cyclooxygenase-2 expression in gastric epithelial cells
27. Subcellular location and differential Ab specificity of arginase in tissue culture and whole animals
28. Synergistic induction of ornithine decarboxylase by asparagine and gut peptides in intestinal crypt cells
29. Arginase I: A limiting factor for nitric oxide and polyamine synthesis by activated macrophages?
30. Elevated arginase I expression in rat aortic smooth muscle cells increases cell proliferation
31. Arginine metabolism: Nitric oxide and beyond
32. + translocation
33. Distinct arginase isoforms expressed in primary and transformed macrophages: Regulation by oxygen tension
34. Differential regulation of arginases and inducible nitric oxide synthase in murine macrophage cells
35. Regulation of the genes for arginase isoforms and related enzymes in mouse macrophages by lipopolysaccharide
36. The involvement of tyrosine kinases, cyclic AMP/protein kinase A, and p38 mitogen-activated protein kinase in IL-13-mediated arginase I induction in macrophages: Its implications in IL-13-inhibited nitric oxide production
37. Glucocorticoids inhibit lipopolysaccharide induced up-regulation of arginase in rat alveolar macrophages
38. Helicobacter pylori infection activates NF-κB in gastric epithelial cells
39. Nitric oxide as a bioregulator of apoptosis
40. NF-κB, inducible nitric oxide synthase and apoptosis by Helicobacter pylori infection
41. Nitric oxide synthase induces macrophage death by apoptosis
42. Suppression of apoptosis by nitric oxide via inhibition of interleukin-1β-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases
43. S-nitrosylation regulates apoptosis
44. Nitric oxide inhibits tumor necrosis factor-α-induced apoptosis by reducing the generation of ceramide
45. Lipopolysaccharide-induced apoptosis of macrophages determines the up-regulation of concentrative nucleoside transporters Cnt1 and Cnt2 through tumor necrosis factorα-dependent and -independent mechanisms
46. Inhibition of ornithine decarboxylase potentiates nitric oxide production in LPS-activated J774 cells
47. Differential gene expression in p53-mediated apoptosis-resistant vs. apoptosis-sensitive tumor cell lines
48. ω-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells
49. Modulatory effect of dexamethasone on ornithine decarboxylase activity and gene expression: A possible post-transcriptional regulation by a neutral metalloprotease
50. Ornithine decarboxylase: Essential in proliferation but not differentiation of human promyelocytic leukemia cells
51. Ornithine decarboxylase is a mediator of c-Myc-induced apoptosis
52. Polyamine depletion protects HL-60 cells from 2-deoxy-D-ribose-induced apoptosis
53. NF-κB activation and susceptibility to apoptosis after polyamine depletion in intestinal epithelial cells
54. Polyamines in cell growth and cell death: Molecular mechanisms and therapeutic applications
55. Induction of apoptosis by excessive polyamine accumulation in ornithine decarboxylase-overproducing L1210 cells
56. Polyamine depletion induces rapid NF-κB activation in IEC-6 cells
57. An essential role for NF-κB in preventing TNF-α-induced cell death
58. Suppression of TNF-α-induced apoptosis by NF-κB
59. Activation of peroxisome proliferator-activated receptor γ suppresses nuclear factor κB-mediated apoptosis induced by Helicobacter pylori in gastric epithelial cells
60. The urea cycle of Helicobacter pylori
61. Helicobacter pylori rocF is required for arginase activity and acid protection in vitro but is not essential for colonization of mice or for urease activity
62. Potential relevance of agmatine as a virulence factor of Helicobacter pylori
63. Helicobacter pylori produces histamine and spermidine