Global analysis of the human gastric epithelial transcriptome altered by Helicobacter pylori eradication in vivo

Gut

Volumn 55, Issue 12, 2006, Pages 1717-1724

  Resnick, M B ^a,b   Sabo, E ^b   Meitner, P A ^b   Kim, S S ^c   Cho, Y ^c   Kim, H K ^c   Tavares, R ^b   Moss, S F ^b  

^a RHODE ISLAND HOSPITAL   (United States)

^b BROWN UNIVERSITY   (United States)

^c Uijeongbu St Mary's Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; CLARITHROMYCIN; MESSENGER RNA; PROTON PUMP INHIBITOR;

ADULT; AGED; ARTICLE; BIOPSY; CONTROLLED STUDY; DNA MICROARRAY; ERADICATION THERAPY; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HELICOBACTER PYLORI; HUMAN; HUMAN TISSUE; LASER CAPTURE MICRODISSECTION; MALE; NUCLEOTIDE SEQUENCE; PEPTIC ULCER; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; STOMACH EPITHELIUM; STOMACH MUCOSA; TRANSCRIPTOMICS; UNINDEXED SEQUENCE;

ADULT; AGED; EPITHELIAL CELLS; FEMALE; GENE EXPRESSION REGULATION; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MALE; MICRODISSECTION; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PEPTIC ULCER; PYLORIC ANTRUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC;

EID: 33845441123     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2006.095646     Document Type: Article

References (58)

1. Suerbaum S, Michetti P. H. pylori infection. N Engl J Med 2002;347:1175-86.
2. Peek RM. Pathogenesis of H. pylori infection. Springer Semin Immunopathol 2005;27:197-215.
3. Backert S, Gressmann H, Kwok T, et al. Gene expression and protein profiling of AGS gastric epithelial cells upon infection with H. pylori. Proteomics 2005;5:3902-18.
4. Myllykangas S, Monni O, Nagy B, et al. Helicobacter pylori infection activates FOS and stress-response genes and alters expression of genes in gastric cancer-specific loci. Genes Chromosomes Cancer 2004;40:334-41.
5. Guillemin K, Salama NR, Tompkins LS, et al. Pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection. Proc Natl Acad Sci USA 2002;99:15136-41.
6. Sepulveda AR, Tao H, Carloni E, et al. Screening of gene expression profiles in gastric epithelial cells induced by Helicobacter pylori using microarray analysis. Aliment Pharmacol Ther 2002;16(Suppl 2):145-57.
7. Bach S, Makristathis A, Rotter M, et al. Expression profiling in AGS cells stimulated with Helicobacter pylori isogenic strains (cagA positive or cagA negative). Infect Immun 2002;70:988-92.
8. Cax JM, Clayton CL, Tomita T, et al. cDNA array analysis of cag pathogenicity island-associated Helicobacter pylori epithelial cell response genes. Infect Immun 2001;69:0970-80.
9. Maeda S, Otsuka M, Hirata Y, et al. cDNA microarray analysis of Helicobacter pylori-mediated alteration of gene expression in gastric cancer cells. Biochem Biophys Res Commun 2001;284:443-9.
10. Chiou CC, Chan CC, Sheu DL, et al. Helicobacter pylori infection induced alteration of gene expression in human gastric cells. Gut 2001;48:598-604.
11. Israel DA, Salama N, Arnold CN, et al. Helicobacter pylori strain-specific differences in genetic content, identified by microarray, influence host inflammatory responses. J Clin Invest 2001;107:611-20.
12. Mannick EE, Schurr JR, Zapata A, et al. Gene expression in gastric biopsies from patients infected with Helicobacter pylori. Scand J Gastroenterol 2004;39:1192-200.
13. Wen S, Felley CP, Bouzourene H, et al. Inflammatory gene profiles in gastric mucosa during Helicobacter pylori infection in humans. J Immunol 2004;172:2595-606.
14. Huff JL, Hansen LM, Solnick JV. Gastric transcription profile of Helicobacter pylori infection in the rhesus macaque. Infect Immun 2004;72:5216-26.
15. Mueller A, Merrell DS, Grimm J, et al. Profiling of microdissected gastric epithelial cells reveals a cell type-specific response to Helicobacter pylori infection. Gastroenterology 2004;127:1446-62.
16. Koehler CI, Mues MB, Dienes HP, et al. Helicobacter pylori genotyping in gastric adenocarcinoma and MALT lymphoma by multiplex PCR analysis of paraffin wax embedded tissues. J Clin Pathol Mol Pathol 2003;56:36-42.
17. Colantuoni C, Henry G, Zeger S, et al. SNOMAD (Standardization and Normalization of MicroArray Data): web-accessible gene expression data analysis. Bioinformatics 2002;18:1540-1.
18. Storey JD, Tibshirani R. Statistical significance for genome-wide studies. Proc Natl Acad Sci USA, 2003;100:9440-5.
19. Dahlquist KD, Salomonis N, Vranizan K, et al. GenMAPP, a new tool for viewing and analyzing microarray data on biological pathways. Nat Genet 2002;31:19-20.
20. Doniger S, Salomonis N, Dahlquist KD, et al. MAPPFinder: using Gene Ontology and GenMAPP to create a global gene-expression profile from microarray data. Genome Biol 2003;4:R7.
21. Kunkel SL, Lukacs NW, Strieter RM. The role of interleukin-8 in the infectious process. Ann N Y Acad Sci 1994;730:134-43.
22. Crabtree JE, Wyatt JI, Trejdosiewicz LK, et al. Interleukin-8 expression in Helicobacter pylori infected, normal, and neoplastic gastroduoaenal mucosa. J Clin Pathol 1994;47:61-6.
23. Yamaoka Y, Kita M, Kodama T, et al. Chemokines in the gastric mucosa in H. pylori infection. Gut 1998;42:609-17.
24. Kumar S, McDonnell PC, Lehr R, et al. Identification and initial characterization of four novel members of the interleukin-1 family. J Biol Chem 2000;275:10308-14.
25. Smith, DE, Renshaw, BR, Ketchem, RR, et al. Four new members expand the interleukin-1 superfamily. J Biol Chem 2000;275:1169-75.
26. El-Omar EM, Rabkin CS, Gammon MD, et al. Increased risk of noncardia gastric cancer associated with proinflammatory cytokine gene polymorphisms. Gastroenterology 2003;124:1193-201.
27. Krauss-Etechmann S, Sammler E, Koletzko S, et al. Chemokine receptor 5 expression in gastric mucosa of Helicobacter pylori-infected and noninfected children. Clin Diagn Lab Immunol 2003;10:22-9.
28. Schmausser B, Endrich S, Brandlein S, et al. The chemokine receptor CCR7 is expressed on epithelium of non-inflamed gastric mucosa, Helicobacter pylori gastritis, gastric carcinoma and its precursor lesions and up-regulated by H. pylori. Clin Exp Immunol 2005;139:323-7.
29. Hamanaka Y, Nakashima M, Wada A, et al. Expression of human beta-defensin 2 (hBD-2) in Helicobacter pylori induced gastritis: antibacterial effect of hBD-2 against Helicobacter pylori. Gut 2001;49:481-7.
30. Du JJ, Dou KF, Peng SY, et al. Study on novel gene GDDR related to gastric cancer. Zhonghua Wai Ke Za Zhi 2005;43:10-13.
31. Westley BR, Griffin SM, May FE. Interaction between TFF1, a gastric tumor suppressor trefoil protein, and TFIZ1, a brichos domain-containing protein with homology to SP-C. Biochemistry 2005;44:7967-75.
32. Lefebvre O, Chenard M-P, Masson R, et al. Gastric mucosa abnormalities and tumorigenesis in mice lacking the pS2 trefoil protein. Science 1996;274:259-2.
33. Henry JA, Bennett MK, Piggott NH, et al. Expression of pNR-2/pS2 protein in diverse human epithelial tumours. Br J Cancer 1991;64:677-82.
34. Muller W, Borchard F. pS2 protein in gastric carcinoma and normal gastric mucosa: association with clinicopathological parameters and patient survival. J Pathol 1993;171:263-9.
35. Park WS, Oh RR, Park JY, et al. Somatic mutations of the trefoil factor family 1 gene in gastric cancer. Gastroenterology 2000;119:691-8.
36. Clyne M, Dillon P, Daly S, et al. Helicobacter pylori interacts with the human single-domain trefoil protein TFF1. Proc Natl Acad Sci USA 2004;101:7409-14.
37. Oien KA, McGregor F, Butler S, et al. Gastrokine 1 is abundantly and specifically expressed in superficial gastric epithelium, down-regulated in gastric carcinoma, and shows high evolutionary conservation. J Pathol 2004;203:789-97.
38. Martin TE, Powell CT, Wang Z, et al. A novel mitogenic protein that is highly expressed in cells of the gastric antrum mucosa. Am J Physiol Gastroinfest Liver Physiol 2003;285:G332-43.
39. Fukui H, Kinoshita Y, Maekawa T, et al. Regenerating gene protein may mediate gastric mucosal proliferation induced by hypergastrinemia in rats. Gastroenterology 1998;115:1483-93.
40. Oue N, Mitoni Y, Aung PP, et al. Expression and localization of Reg IV in human neoplastic and non-neoplastic tissues: Reg IV expression is associated with intestinal and neuroendocrine differentiation in gastric adenocarcinoma. J Pathol 2005;207:185-98.
41. Dhar DK, Udagawa J, Ishihara S, et al. Expression of regenerating gene I in gastric adenocarcinomas: correlation with tumor differentiation status and patient survival. Cancer 2004;100:1130-6.
42. Sekikawa A, Fukui H, Fujii S, et al. REG I protein may function as a trophic and/or anti-apoptotic factor in the development of gastric cancer. Gastroenterology 2005;128:642-53.
43. Yoshino N, Ishihara S, Rumi MA, et al. IL-8 regulates expression of Reg protein in Helicobacter pylori-infected gastric mucosa. Am J Gastroenterol 2005;100:2157-66.
44. Yi HK, Hwang PH, Yang DH, et al. Expression of the insulin-like growth factors (IGFs) and the IGF-binding proteins (IGFBPs) in human gastric cancer cells. Eur J Cancer 2001;37:2257-63.
45. Yatsuya H, Toyoshima H, Tamakoshi K, et al. Serum levels of insulin-like growth factor I, II, and binding protein 3, transforming growth factor beta-1, soluble fas ligand and superoxide dismutase activity in stomach cancer cases and their controls in the JACC Study. J Epidemiol 2005;15(Suppl 2):S120-5.
46. Shirin H, Weinstein IB, Moss SF. Effects of H. pylori infection of gastric epithelial cells on cell cycle control. Front Bioscience 2001;6:e104-18.
47. Goodwin RG, Din WS, Davis-Smith T, et al. Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor. Eur J Immunol 1993;23:2631-41.
48. Wu LC, Wang ZW, Tsan JT, et al. Identification of a RING protein that can interact in vivo with the BRCA1 gene product. Nat Genet 1996;14:430-40.
49. Piacentini M, Evangelisti C, Mastroberadino PG, et al. Does prothymosin-alpha act as a molecular switch between apoptosis and autophagy? Cell Death Differ 2003;10:937-9.
50. Yunta M, Lazo PA. Apoptosis protection and survival signal by the CD53 tetraspanin antigen. Oncogene 2003;27:1219-24.
51. Thome M, Schneider P, Hofmann K, et al. Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors. Nature 1997;386:517-21.
52. Earnshaw WC. Keeping survivin nimble at centromeres in mitosis. Science 2005;310:1443-4.
53. Player A, Barrett JC, Kawasaki ES. Laser capture microdissection, microarrays and the precise definition of a cancer cell. Expert Rev Mol Diagn 2004;4:831-40.
54. Luzzi V, Mahadevappa M, Raja R, et al. Accurate and reproducible gene expression profiles from laser capture microdissection, transcript amplification, and high density oligonucleotide microarray analysis. J Mol Diagn 2003;5:9-14.
55. Upson JJ, Stoyanova R, Cooper HS, et al. Optimized procedures for microarray analysis of histological specimens processed by laser capture microdissection. J Cell Pnysiol 2004;201:366-73.
56. Ma XJ, Wang Z, Ryan P, et al. A two-gene expression ratio predicts clinical outcome in breast cancer patients treated with tamoxifen. Cancer Cell 2004;5:607-16.
57. Kim SS, Meitner P, Konkin TA, et al. Expression of Skp2, c-Myc and p27 proteins but not mRNA after H. pylori eradication in chronic gastritis. Mod Pathol 2006;19:49-58.
58. kip1 in gastric epithelial cells. Cancer Res 2003;63:4739-46.