The apolipoprotein E-mimetic peptide COG112 inhibits the inflammatory response to Citrobacter rodentium in colonic epithelial cells by preventing NF-κB activation

Journal of Biological Chemistry

Volumn 283, Issue 24, 2008, Pages 16752-16761

  Singh, Kshipra ^a,b   Chaturvedi, Rupesh ^a,b   Asim, Mohammad ^a,b   Barry, Daniel P ^a,b   Lewis, Nuruddeen D ^a   Vitek, Michael P ^c   Wilson, Keith T ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Optimal Screening Vehicles Division   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BACTERIOLOGY; BIOMIMETICS; ENZYME ACTIVITY; ENZYMES; ESCHERICHIA COLI; PEPTIDES; PLASMA WAVES; PROTEINS;

ADDITIVE EFFECTS; APOLIPOPROTEIN; CHEMOKINES; COLONIC MUCOSAS; ELECTROMOBILITY SHIFT ASSAYS; EPITHELIAL CELLS; IMMUNOBLOTTING; IMMUNOMODULATORY EFFECTS; INFLAMMATORY BOWEL DISEASES; INFLAMMATORY RESPONSES; KINASE ACTIVITIES; KINASE COMPLEXES; NEUROINFLAMMATION; NUCLEAR TRANSLOCATIONS; PROINFLAMMATORY; PROTEIN EXPRESSIONS; SIGNALING EVENTS; SYNTHASE; YOUNG ADULTS;

ENZYME INHIBITION;

3 (4 METHYLPHENYLSULFONYL) 2 PROPENENITRILE; APOLIPOPROTEIN E; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CHEMOKINE; I KAPPA B ALPHA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MACROPHAGE INFLAMMATORY PROTEIN 1; MESSENGER RNA; PEPTIDE COG112; PEPTIDE DERIVATIVE; SYNAPTOTAGMIN I; UNCLASSIFIED DRUG; COG112 PEPTIDE; NFKB1 PROTEIN, MOUSE; PEPTIDE;

ANIMAL CELL; ARTICLE; CITROBACTER RODENTIUM; COLITIS; COLON MUCOSA; CONTROLLED STUDY; DRUG INHIBITION; ENZYME ACTIVITY; EPITHELIUM CELL; GEL MOBILITY SHIFT ASSAY; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; ANIMAL; BIOLOGICAL MODEL; CHEMISTRY; COLON; DOSE RESPONSE; ESCHERICHIA COLI; INFLAMMATION; METABOLISM; MICROBIOLOGY;

CITROBACTER RODENTIUM; ESCHERICHIA COLI; MUS; RODENTIA;

ANIMALS; APOLIPOPROTEINS E; CITROBACTER RODENTIUM; COLON; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; ESCHERICHIA COLI; I-KAPPA B KINASE; INFLAMMATION; MICE; MODELS, BIOLOGICAL; NF-KAPPA B; NF-KAPPA B P50 SUBUNIT; NITRIC OXIDE SYNTHASE TYPE II; PEPTIDES;

EID: 47749138219     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M710530200     Document Type: Article

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