-
1
-
-
54449089923
-
Hepatocellular cancer arises from loss of transforming growth factor beta signaling adaptor protein embryonic liver fodrin through abnormal angiogenesis
-
Baek H.J., Lim S.C., Kitisin K., Jogunoori W., Tang Y., Marshall M.B., Mishra B., Kim T.H., Cho K.H., Kim S.S. and Mishra L. (2008). Hepatocellular cancer arises from loss of transforming growth factor beta signaling adaptor protein embryonic liver fodrin through abnormal angiogenesis. Hepatology 48, 1128-1137.
-
(2008)
Hepatology
, vol.48
, pp. 1128-1137
-
-
Baek, H.J.1
Lim, S.C.2
Kitisin, K.3
Jogunoori, W.4
Tang, Y.5
Marshall, M.B.6
Mishra, B.7
Kim, T.H.8
Cho, K.H.9
Kim, S.S.10
Mishra, L.11
-
2
-
-
70349290728
-
Evolution of spectrin function in cytoskeletal and membrane networks
-
Baines A.J. (2009). Evolution of spectrin function in cytoskeletal and membrane networks. Biochem. Soc. Trans. 37, 796-803.
-
(2009)
Biochem. Soc. Trans.
, vol.37
, pp. 796-803
-
-
Baines, A.J.1
-
3
-
-
0034958883
-
Spectrin and ankyrin-based pathways: Metazoan inventions for integrating cells into tissues
-
Bennett V. and Baines A.J. (2001). Spectrin and ankyrin-based pathways: Metazoan inventions for integrating cells into tissues. Physiol. Rev. 81, 1353-1392.
-
(2001)
Physiol. Rev.
, vol.81
, pp. 1353-1392
-
-
Bennett, V.1
Baines, A.J.2
-
5
-
-
65449178092
-
Localization and structure of the ankyrinbinding site on beta2-spectrin
-
Davis L., Abdi K., Machius M., Brautigam C., Tomchick D.R., Bennett V. and Michaely P. (2009). Localization and structure of the ankyrinbinding site on beta2-spectrin. J. Biol. Chem. 284, 6982-6987.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 6982-6987
-
-
Davis, L.1
Abdi, K.2
Machius, M.3
Brautigam, C.4
Tomchick, D.R.5
Bennett, V.6
Michaely, P.7
-
6
-
-
0142104985
-
Smad-dependent and smadindependent pathways in tgf-beta family signalling
-
Derynck R. and Zhang Y.E. (2003). Smad-dependent and smadindependent pathways in tgf-beta family signalling. Nature 425, 577-584.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
7
-
-
65949114866
-
Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma
-
Erkan M., Reiser-Erkan C., Michalski C.W., Deucker S., Sauliunaite D., Streit S., Esposito I., Friess H. and Kleeff J. (2009). Cancer-stellate cell interactions perpetuate the hypoxia-fibrosis cycle in pancreatic ductal adenocarcinoma. Neoplasia 11, 497-508.
-
(2009)
Neoplasia
, vol.11
, pp. 497-508
-
-
Erkan, M.1
Reiser-Erkan, C.2
Michalski, C.W.3
Deucker, S.4
Sauliunaite, D.5
Streit, S.6
Esposito, I.7
Friess, H.8
Kleeff, J.9
-
8
-
-
34247236139
-
Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity
-
Erkan M., Kleeff J., Gorbachevski A., Reiser C., Mitkus T., Esposito I., Giese T., Buchler M.W., Giese N.A. and Friess H. (2007). Periostin creates a tumor-supportive microenvironment in the pancreas by sustaining fibrogenic stellate cell activity. Gastroenterology 132, 1447-1464.
-
(2007)
Gastroenterology
, vol.132
, pp. 1447-1464
-
-
Erkan, M.1
Kleeff, J.2
Gorbachevski, A.3
Reiser, C.4
Mitkus, T.5
Esposito, I.6
Giese, T.7
Buchler, M.W.8
Giese, N.A.9
Friess, H.10
-
9
-
-
34748822998
-
Hypothetical progression model of pancreatic cancer with origin in the centroacinar-acinar compartment
-
Esposito I., Seiler C., Bergmann F., Kleeff J., Friess H. and Schirmacher P. (2007). Hypothetical progression model of pancreatic cancer with origin in the centroacinar-acinar compartment. Pancreas 35, 212-217.
-
(2007)
Pancreas
, vol.35
, pp. 212-217
-
-
Esposito, I.1
Seiler, C.2
Bergmann, F.3
Kleeff, J.4
Friess, H.5
Schirmacher, P.6
-
10
-
-
43449107352
-
Most pancreatic cancer resections are r1 resections
-
Esposito I., Kleeff J., Bergmann F., Reiser C., Herpel E., Friess H., Schirmacher P. and Buchler M.W. (2008). Most pancreatic cancer resections are r1 resections. An. Surg. Oncol. 15, 1651-1660.
-
(2008)
An. Surg. Oncol.
, vol.15
, pp. 1651-1660
-
-
Esposito, I.1
Kleeff, J.2
Bergmann, F.3
Reiser, C.4
Herpel, E.5
Friess, H.6
Schirmacher, P.7
Buchler, M.W.8
-
11
-
-
0027131252
-
Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival
-
Friess H., Yamanaka Y., Buchler M., Ebert M., Beger H.G., Gold L.I. and Korc M. (1993). Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology 105, 1846-1856.
-
(1993)
Gastroenterology
, vol.105
, pp. 1846-1856
-
-
Friess, H.1
Yamanaka, Y.2
Buchler, M.3
Ebert, M.4
Beger, H.G.5
Gold, L.I.6
Korc, M.7
-
13
-
-
0033588274
-
Structures of two repeats of spectrin suggest models of flexibility
-
Grum V.L., Li D., MacDonald R.I. and Mondragon A. (1999). Structures of two repeats of spectrin suggest models of flexibility. Cell 98, 523-535.
-
(1999)
Cell
, vol.98
, pp. 523-535
-
-
Grum, V.L.1
Li, D.2
McDonald, R.I.3
Mondragon, A.4
-
14
-
-
0030593038
-
Dpc4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn S.A., Schutte M., Hoque A.T., Moskaluk C.A., da Costa L.T., Rozenblum E., Weinstein C.L., Fischer A., Yeo C.J., Hruban R.H. and Kern S.E. (1996). Dpc4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271, 350-353.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
15
-
-
0028679744
-
Actin-binding proteins 1: Spectrin superfamily
-
Hartwig J.H. (1994). Actin-binding proteins 1: Spectrin superfamily. Protein Profile 1, 706-778.
-
(1994)
Protein Profile
, vol.1
, pp. 706-778
-
-
Hartwig, J.H.1
-
16
-
-
67650874081
-
Cancer statistics, 2009
-
Jemal A., Siegel R., Ward E., Hao Y., Xu J. and Thun M.J. (2009). Cancer statistics, 2009. CA Cancer J. Clin. 59, 225-249.
-
(2009)
CA Cancer J. Clin.
, vol.59
, pp. 225-249
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Thun, M.J.6
-
17
-
-
52149123619
-
Core signaling pathways in human pancreatic cancers revealed by global genomic analyses
-
Jones S., Zhang X., Parsons D.W., Lin J.C., Leary R.J., Angenendt P., Mankoo P., Carter H., Kamiyama H., Jimeno A., Hong S.M., Fu B., Lin M.T., Calhoun E.S., Kamiyama M., Walter K., Nikolskaya T., Nikolsky Y., Hartigan J., Smith D.R., Hidalgo M., Leach S.D., Klein A.P., Jaffee E.M., Goggins M., Maitra A., Iacobuzio-Donahue C., Eshleman J.R., Kern S.E., Hruban R.H., Karchin R., Papadopoulos N., Parmigiani G., Vogelstein B., Velculescu V.E. and Kinzler K.W. (2008). Core signaling pathways in human pancreatic cancers revealed by global genomic analyses. Science 321, 1801-1806.
-
(2008)
Science
, vol.321
, pp. 1801-1806
-
-
Jones, S.1
Zhang, X.2
Parsons, D.W.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Kamiyama, H.9
Jimeno, A.10
Hong, S.M.11
Fu, B.12
Lin, M.T.13
Calhoun, E.S.14
Kamiyama, M.15
Walter, K.16
Nikolskaya, T.17
Nikolsky, Y.18
Hartigan, J.19
Smith, D.R.20
Hidalgo, M.21
Leach, S.D.22
Klein, A.P.23
Jaffee, E.M.24
Goggins, M.25
Maitra, A.26
Iacobuzio-Donahue, C.27
Eshleman, J.R.28
Kern, S.E.29
Hruban, R.H.30
Karchin, R.31
Papadopoulos, N.32
Parmigiani, G.33
Vogelstein, B.34
Velculescu, V.E.35
Kinzler, K.W.36
more..
-
18
-
-
28544436147
-
Inactivation of elf/tgf-beta signaling in human gastrointestinal cancer
-
Katuri V., Tang Y., Marshall B., Rashid A., Jogunoori W., Volpe E.A., Sidawy A.N., Evans S., Blay J., Gallicano G.I., Premkumar Reddy E., Mishra L. and Mishra B. (2005). Inactivation of elf/tgf-beta signaling in human gastrointestinal cancer. Oncogene 24, 8012-8024.
-
(2005)
Oncogene
, vol.24
, pp. 8012-8024
-
-
Katuri, V.1
Tang, Y.2
Marshall, B.3
Rashid, A.4
Jogunoori, W.5
Volpe, E.A.6
Sidawy, A.N.7
Evans, S.8
Blay, J.9
Gallicano, G.I.10
Premkumar Reddy, E.11
Mishra, L.12
Mishra, B.13
-
19
-
-
33646470279
-
Tgf-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: Role of the beta-spectrin, elf
-
Kim S.S., Shetty K., Katuri V., Kitisin K., Baek H.J., Tang Y., Marshall B., Johnson L., Mishra B. and Mishra L. (2006). Tgf-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: Role of the beta-spectrin, elf. Biochem. Biophys. Res. Commun. 344, 1216-1223.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.344
, pp. 1216-1223
-
-
Kim, S.S.1
Shetty, K.2
Katuri, V.3
Kitisin, K.4
Baek, H.J.5
Tang, Y.6
Marshall, B.7
Johnson, L.8
Mishra, B.9
Mishra, L.10
-
20
-
-
35848951652
-
Disruption of transforming growth factor-beta signaling through betaspectrin elf leads to hepatocellular cancer through cyclin d1 activation
-
Kitisin K., Ganesan N., Tang Y., Jogunoori W., Volpe E.A., Kim S.S., Katuri V., Kallakury B., Pishvaian M., Albanese C., Mendelson J., Zasloff M., Rashid A., Fishbein T., Evans S.R., Sidawy A., Reddy E.P., Mishra B., Johnson L.B., Shetty K. and Mishra L. (2007). Disruption of transforming growth factor-beta signaling through betaspectrin elf leads to hepatocellular cancer through cyclin d1 activation. Oncogene 26, 7103-7110.
-
(2007)
Oncogene
, vol.26
, pp. 7103-7110
-
-
Kitisin, K.1
Ganesan, N.2
Tang, Y.3
Jogunoori, W.4
Volpe, E.A.5
Kim, S.S.6
Katuri, V.7
Kallakury, B.8
Pishvaian, M.9
Albanese, C.10
Mendelson, J.11
Zasloff, M.12
Rashid, A.13
Fishbein, T.14
Evans, S.R.15
Sidawy, A.16
Reddy, E.P.17
Mishra, B.18
Johnson, L.B.19
Shetty, K.20
Mishra, L.21
more..
-
21
-
-
0033573974
-
Smad6 suppresses tgf-beta-induced growth inhibition in colo-357 pancreatic cancer cells and is overexpressed in pancreatic cancer
-
Kleeff J., Maruyama H., Friess H., Buchler M.W., Falb D. and Korc M. (1999a). Smad6 suppresses tgf-beta-induced growth inhibition in colo-357 pancreatic cancer cells and is overexpressed in pancreatic cancer. Biochem. Biophys. Res. Commun. 255, 268-273.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.255
, pp. 268-273
-
-
Kleeff, J.1
Maruyama, H.2
Friess, H.3
Buchler, M.W.4
Falb, D.5
Korc, M.6
-
22
-
-
0033598408
-
The tgf-beta signaling inhibitor smad7 enhances tumorigenicity in pancreatic cancer
-
Kleeff J., Ishiwata T., Maruyama H., Friess H., Truong P., Buchler M.W., Falb D. and Korc M. (1999b). The tgf-beta signaling inhibitor smad7 enhances tumorigenicity in pancreatic cancer. Oncogene 18, 5363-5372.
-
(1999)
Oncogene
, vol.18
, pp. 5363-5372
-
-
Kleeff, J.1
Ishiwata, T.2
Maruyama, H.3
Friess, H.4
Truong, P.5
Buchler, M.W.6
Falb, D.7
Korc, M.8
-
23
-
-
0002426462
-
Ductal adenocarcinoma of the pancreas. In: Who classification of tumours
-
S.R. Hamilton and L.A. Aaltonen (eds). IARC Press. Lyon
-
Klöppel G., Hruban R.H., Longnecker D.S., Adler G., Kern S.E. and Partanen T.J. (2000). Ductal adenocarcinoma of the pancreas. In: Who classification of tumours. Pathology and genetics of tumours of the digestive system. S.R. Hamilton and L.A. Aaltonen (eds). IARC Press. Lyon. pp. 221-230.
-
(2000)
Pathology and genetics of tumours of the digestive system
, pp. 221-230
-
-
Klöppel, G.1
Hruban, R.H.2
Longnecker, D.S.3
Adler, G.4
Kern, S.E.5
Partanen, T.J.6
-
25
-
-
0034644472
-
Tgfbeta signaling in growth control, cancer, and heritable disorders
-
Massague J., Blain S.W. and Lo R.S. (2000). Tgfbeta signaling in growth control, cancer, and heritable disorders. Cell 103, 295-309.
-
(2000)
Cell
, vol.103
, pp. 295-309
-
-
Massague, J.1
Blain, S.W.2
Lo, R.S.3
-
26
-
-
26444520301
-
The role of praja and elf in tgfbeta signaling and gastric cancer
-
Mishra L., Katuri V. and Evans S. (2005). The role of praja and elf in tgfbeta signaling and gastric cancer. Cancer Biol. Ther. 4, 694-699.
-
(2005)
Cancer Biol. Ther.
, vol.4
, pp. 694-699
-
-
Mishra, L.1
Katuri, V.2
Evans, S.3
-
27
-
-
0033552955
-
Elf3 encodes a novel 200-kd beta-spectrin: Role in liver development
-
Mishra L., Cai T., Yu P., Monga S.P. and Mishra B. (1999). Elf3 encodes a novel 200-kd beta-spectrin: Role in liver development. Oncogene 18, 353-364.
-
(1999)
Oncogene
, vol.18
, pp. 353-364
-
-
Mishra, L.1
Cai, T.2
Yu, P.3
Monga, S.P.4
Mishra, B.5
-
28
-
-
0031936709
-
Identification of elf1, a beta-spectrin, in early mouse liver development
-
Mishra L., Cai T., Levine A., Weng D., Mezey E., Mishra B. and Gearhart J. (1998). Identification of elf1, a beta-spectrin, in early mouse liver development. Int. J. Dev. Biol. 42, 221-224.
-
(1998)
Int. J. Dev. Biol.
, vol.42
, pp. 221-224
-
-
Mishra, L.1
Cai, T.2
Levine, A.3
Weng, D.4
Mezey, E.5
Mishra, B.6
Gearhart, J.7
-
29
-
-
0020790044
-
The influence of membrane skeleton on red cell deformability, membrane material properties, and shape
-
Mohandas N., Chasis J.A. and Shohet S.B. (1983). The influence of membrane skeleton on red cell deformability, membrane material properties, and shape. Semin. Hematol. 20, 225-242.
-
(1983)
Semin. Hematol.
, vol.20
, pp. 225-242
-
-
Mohandas, N.1
Chasis, J.A.2
Shohet, S.B.3
-
30
-
-
21344464960
-
Defects in ankyrin-based cellular pathways in metazoan physiology
-
Mohler P.J. and Bennett V. (2005). Defects in ankyrin-based cellular pathways in metazoan physiology. Front. Biosci. 10, 2832-2840.
-
(2005)
Front. Biosci.
, vol.10
, pp. 2832-2840
-
-
Mohler, P.J.1
Bennett, V.2
-
31
-
-
58149173406
-
Hypoxia-inducible proto-oncogene pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma
-
Reiser-Erkan C., Erkan M., Pan Z., Bekasi S., Giese N.A., Streit S., Michalski C.W., Friess H. and Kleeff J. (2008). Hypoxia-inducible proto-oncogene pim-1 is a prognostic marker in pancreatic ductal adenocarcinoma. Cancer Biol. Ther. 7, 1352-1359.
-
(2008)
Cancer Biol. Ther.
, vol.7
, pp. 1352-1359
-
-
Reiser-Erkan, C.1
Erkan, M.2
Pan, Z.3
Bekasi, S.4
Giese, N.A.5
Streit, S.6
Michalski, C.W.7
Friess, H.8
Kleeff, J.9
-
32
-
-
0242499448
-
Cytostatic and apoptotic actions of tgf-beta in homeostasis and cancer
-
Siegel P.M. and Massague J. (2003). Cytostatic and apoptotic actions of tgf-beta in homeostasis and cancer. Nat. Rev. Cancer 3, 807-821.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 807-821
-
-
Siegel, P.M.1
Massague, J.2
-
33
-
-
0021272595
-
Erythrocyte spectrin is comprised of many homologous triple helical segments
-
Speicher D.W. and Marchesi V.T. (1984). Erythrocyte spectrin is comprised of many homologous triple helical segments. Nature 311, 177-180.
-
(1984)
Nature
, vol.311
, pp. 177-180
-
-
Speicher, D.W.1
Marchesi, V.T.2
-
34
-
-
0037462502
-
Disruption of transforming growth factor-beta signaling in elf beta-spectrin-deficient mice
-
Tang Y., Katuri V., Dillner A., Mishra B., Deng C.X. and Mishra L. (2003). Disruption of transforming growth factor-beta signaling in elf beta-spectrin-deficient mice. Science 299, 574-577.
-
(2003)
Science
, vol.299
, pp. 574-577
-
-
Tang, Y.1
Katuri, V.2
Dillner, A.3
Mishra, B.4
Deng, C.X.5
Mishra, L.6
-
35
-
-
20144378766
-
Transforming growth factor-beta suppresses nonmetastatic colon cancer through smad4 and adaptor protein elf at an early stage of tumorigenesis
-
Tang Y., Katuri V., Srinivasan R., Fogt F., Redman R., Anand G., Said A., Fishbein T., Zasloff M., Reddy E.P., Mishra B. and Mishra L. (2005). Transforming growth factor-beta suppresses nonmetastatic colon cancer through smad4 and adaptor protein elf at an early stage of tumorigenesis. Cancer Res. 65, 4228-4237.
-
(2005)
Cancer Res.
, vol.65
, pp. 4228-4237
-
-
Tang, Y.1
Katuri, V.2
Srinivasan, R.3
Fogt, F.4
Redman, R.5
Anand, G.6
Said, A.7
Fishbein, T.8
Zasloff, M.9
Reddy, E.P.10
Mishra, B.11
Mishra, L.12
-
36
-
-
40649116943
-
Progenitor/stem cells give rise to liver cancer due to aberrant tgf-beta and il-6 signaling
-
Tang Y., Kitisin K., Jogunoori W., Li C., Deng C.X., Mueller S.C., Ressom H.W., Rashid A., He A.R., Mendelson J.S., Jessup J.M., Shetty K., Zasloff M., Mishra B., Reddy E.P., Johnson L. and Mishra L. (2008). Progenitor/stem cells give rise to liver cancer due to aberrant tgf-beta and il-6 signaling. Proc. Natl. Acad. Sci. USA 105, 2445-2450.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 2445-2450
-
-
Tang, Y.1
Kitisin, K.2
Jogunoori, W.3
Li, C.4
Deng, C.X.5
Mueller, S.C.6
Ressom, H.W.7
Rashid, A.8
He, A.R.9
Mendelson, J.S.10
Jessup, J.M.11
Shetty, K.12
Zasloff, M.13
Mishra, B.14
Reddy, E.P.15
Johnson, L.16
Mishra, L.17
-
37
-
-
35348901453
-
Basics of tgf-beta and pancreatic cancer
-
Truty M.J. and Urrutia R. (2007). Basics of tgf-beta and pancreatic cancer. Pancreatology 7, 423-435.
-
(2007)
Pancreatology
, vol.7
, pp. 423-435
-
-
Truty, M.J.1
Urrutia, R.2
-
38
-
-
0032711157
-
Enhanced expression of the type ii transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer
-
Wagner M., Kleeff J., Friess H., Buchler M.W. and Korc M. (1999). Enhanced expression of the type ii transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer. Pancreas 19, 370-376.
-
(1999)
Pancreas
, vol.19
, pp. 370-376
-
-
Wagner, M.1
Kleeff, J.2
Friess, H.3
Buchler, M.W.4
Korc, M.5
-
39
-
-
34547830182
-
Molecular pathogenesis of pancreatic cancer: Advances and challenges
-
Welsch T., Kleeff J. and Friess H. (2007). Molecular pathogenesis of pancreatic cancer: Advances and challenges. Curr. Mol. Med. 7, 504-521.
-
(2007)
Curr. Mol. Med.
, vol.7
, pp. 504-521
-
-
Welsch, T.1
Kleeff, J.2
Friess, H.3
-
40
-
-
34547789841
-
Tgf-beta signaling alterations and susceptibility to colorectal cancer
-
Spec No 1
-
Xu Y. and Pasche B. (2007). Tgf-beta signaling alterations and susceptibility to colorectal cancer. Hum. Mol. Genet. 16 Spec No 1, R14-20.
-
(2007)
Hum. Mol. Genet.
, vol.16
-
-
Xu, Y.1
Pasche, B.2
-
41
-
-
84861361652
-
-
Accepted May 17
-
Accepted May 17, 2010
-
(2010)
-
-
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