메뉴 건너뛰기




Volumn 48, Issue 4, 2008, Pages 1128-1137

Hepatocellular cancer arises from loss of transforming growth factor beta signaling adaptor protein embryonic liver fodrin through abnormal angiogenesis

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTOR PROTEIN; FODRIN; RETINOBLASTOMA PROTEIN; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA; ACTIN BINDING PROTEIN; CARRIER PROTEIN;

EID: 54449089923     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.22460     Document Type: Article
Times cited : (64)

References (49)
  • 1
    • 0035888074 scopus 로고    scopus 로고
    • Estimating the world cancer burden: Globocan 2000
    • Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world cancer burden: Globocan 2000. Int J Cancer 2001;94:153-156.
    • (2001) Int J Cancer , vol.94 , pp. 153-156
    • Parkin, D.M.1    Bray, F.2    Ferlay, J.3    Pisani, P.4
  • 2
    • 7044231396 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Recent trends in the United States
    • El-Serag HB. Hepatocellular carcinoma: Recent trends in the United States. Gastroenterology 2004;127:S27-S34.
    • (2004) Gastroenterology , vol.127
    • El-Serag, H.B.1
  • 3
    • 20344366296 scopus 로고    scopus 로고
    • Hepatocellular carcinoma: Molecular pathways and new therapeutic targets
    • Roberts LR, Gores GJ. Hepatocellular carcinoma: Molecular pathways and new therapeutic targets. Semin Liver Dis 2005;25:212-225.
    • (2005) Semin Liver Dis , vol.25 , pp. 212-225
    • Roberts, L.R.1    Gores, G.J.2
  • 5
    • 3042761526 scopus 로고    scopus 로고
    • Angiogenesis in hepatocellular carcinoma: The retrospectives and perspectives
    • Sun HC, Tang ZY. Angiogenesis in hepatocellular carcinoma: The retrospectives and perspectives. J Cancer Res Clin Oncol 2004;130:307-319.
    • (2004) J Cancer Res Clin Oncol , vol.130 , pp. 307-319
    • Sun, H.C.1    Tang, Z.Y.2
  • 6
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 7
    • 0037872699 scopus 로고    scopus 로고
    • Angiogenesis in ischemic and neoplastic disorders
    • Semenza GL. Angiogenesis in ischemic and neoplastic disorders. Annu Rev Med 2003;54:17-28.
    • (2003) Annu Rev Med , vol.54 , pp. 17-28
    • Semenza, G.L.1
  • 8
    • 3242663393 scopus 로고    scopus 로고
    • Participation of cyclin D1 deregulation in TNP-470-mediated cytostatic effect: Involvement of senescence
    • Lien WH, Chen CK, Lai LY, Chen YH, Wu MP, Wu LW. Participation of cyclin D1 deregulation in TNP-470-mediated cytostatic effect: Involvement of senescence. Biochem Pharmacol 2004;68:729-738.
    • (2004) Biochem Pharmacol , vol.68 , pp. 729-738
    • Lien, W.H.1    Chen, C.K.2    Lai, L.Y.3    Chen, Y.H.4    Wu, M.P.5    Wu, L.W.6
  • 9
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • Hanahan D, Folkman J. Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 1996;86:353-364.
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 10
  • 11
    • 7844240481 scopus 로고    scopus 로고
    • Disruption of the antiproliferative TGF-beta signaling pathways in human pancreatic cancer cells
    • Villanueva A, Garcia C, Paules AB, Vicente M, Megias M, Reyes G, et al. Disruption of the antiproliferative TGF-beta signaling pathways in human pancreatic cancer cells. Oncogene 1998;17:1969-1978.
    • (1998) Oncogene , vol.17 , pp. 1969-1978
    • Villanueva, A.1    Garcia, C.2    Paules, A.B.3    Vicente, M.4    Megias, M.5    Reyes, G.6
  • 12
    • 0035860239 scopus 로고    scopus 로고
    • Expression of TGF-beta signaling genes in the normal, premalignant, and malignant human trophoblast: Loss of smad3 in choriocarcinoma cells
    • Xu G, Chakraborty C, Lala PK. Expression of TGF-beta signaling genes in the normal, premalignant, and malignant human trophoblast: Loss of smad3 in choriocarcinoma cells. Biochem Biophys Res Commun 2001; 287:47-55.
    • (2001) Biochem Biophys Res Commun , vol.287 , pp. 47-55
    • Xu, G.1    Chakraborty, C.2    Lala, P.K.3
  • 13
    • 0033555627 scopus 로고    scopus 로고
    • Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers
    • Grady WM, Myeroff LL, Swinler SE, Rajput A, Thiagalingam S, Lutterbaugh JD, et al. Mutational inactivation of transforming growth factor beta receptor type II in microsatellite stable colon cancers. Cancer Res 1999;59:320-324.
    • (1999) Cancer Res , vol.59 , pp. 320-324
    • Grady, W.M.1    Myeroff, L.L.2    Swinler, S.E.3    Rajput, A.4    Thiagalingam, S.5    Lutterbaugh, J.D.6
  • 14
    • 0034795917 scopus 로고    scopus 로고
    • Comprehensive analysis of SMAD4 mutations and protein expression in juvenile polyposis: Evidence for a distinct genetic pathway and polyp morphology in SMAD4 mutation carriers
    • Woodford-Richens KL, Rowan AJ, Poulsom R, Bevan S, Salovaara R, Aaltonen LA, et al. Comprehensive analysis of SMAD4 mutations and protein expression in juvenile polyposis: Evidence for a distinct genetic pathway and polyp morphology in SMAD4 mutation carriers. Am J Pathol 2001;159:1293-1300.
    • (2001) Am J Pathol , vol.159 , pp. 1293-1300
    • Woodford-Richens, K.L.1    Rowan, A.J.2    Poulsom, R.3    Bevan, S.4    Salovaara, R.5    Aaltonen, L.A.6
  • 15
    • 30144440059 scopus 로고    scopus 로고
    • Transforming growth factor-beta signal transduction in angiogenesis and vascular disorders
    • Bertolino P, Deckers M, Lebrin F, ten Dijke P. Transforming growth factor-beta signal transduction in angiogenesis and vascular disorders. Chest 2005;128:585S-590S.
    • (2005) Chest , vol.128
    • Bertolino, P.1    Deckers, M.2    Lebrin, F.3    ten Dijke, P.4
  • 17
    • 0030926005 scopus 로고    scopus 로고
    • A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity
    • Feng XH, Derynck R. A kinase subdomain of transforming growth factor-beta (TGF-beta) type I receptor determines the TGF-beta intracellular signaling specificity. EMBO J 1997;16:3912-3923.
    • (1997) EMBO J , vol.16 , pp. 3912-3923
    • Feng, X.H.1    Derynck, R.2
  • 18
    • 0024281442 scopus 로고
    • Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells
    • Kimchi A, Wang XF, Weinberg RA, Cheifetz S, Massague J. Absence of TGF-beta receptors and growth inhibitory responses in retinoblastoma cells. Science 1988;240:196-199.
    • (1988) Science , vol.240 , pp. 196-199
    • Kimchi, A.1    Wang, X.F.2    Weinberg, R.A.3    Cheifetz, S.4    Massague, J.5
  • 19
    • 26444585020 scopus 로고    scopus 로고
    • Transforming growth factor-beta signaling in stem cells and cancer
    • Mishra L, Derynck R, Mishra B. Transforming growth factor-beta signaling in stem cells and cancer. Science 2005;310:68-71.
    • (2005) Science , vol.310 , pp. 68-71
    • Mishra, L.1    Derynck, R.2    Mishra, B.3
  • 20
    • 0033880909 scopus 로고    scopus 로고
    • Spectrin tethers and mesh in the biosynthetic pathway
    • De Matteis MA, Morrow JS. Spectrin tethers and mesh in the biosynthetic pathway. J Cell Sci 2000;113(Pt 13):2331-2343.
    • (2000) J Cell Sci , vol.113 , Issue.PART 13 , pp. 2331-2343
    • De Matteis, M.A.1    Morrow, J.S.2
  • 21
    • 0037462502 scopus 로고    scopus 로고
    • Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice
    • Tang Y, Katuri V, Dillner A, Mishra B, Deng CX, Mishra L. Disruption of transforming growth factor-beta signaling in ELF beta-spectrin-deficient mice. Science 2003;299:574-577.
    • (2003) Science , vol.299 , pp. 574-577
    • Tang, Y.1    Katuri, V.2    Dillner, A.3    Mishra, B.4    Deng, C.X.5    Mishra, L.6
  • 22
    • 0034951680 scopus 로고    scopus 로고
    • Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development
    • Weinstein M, Monga SP, Liu Y, Brodie SG, Tang Y, Li C, et al. Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on beta1-integrin to promote normal liver development. Mol Cell Biol 2001;21:5122-5131.
    • (2001) Mol Cell Biol , vol.21 , pp. 5122-5131
    • Weinstein, M.1    Monga, S.P.2    Liu, Y.3    Brodie, S.G.4    Tang, Y.5    Li, C.6
  • 23
    • 11144299533 scopus 로고    scopus 로고
    • Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-spectrin, in primary biliary cirrhosis
    • Mishra B, Tang Y, Katuri V, Fleury T, Said AH, Rashid A, et al. Loss of cooperative function of transforming growth factor-beta signaling proteins, smad3 with embryonic liver fodrin, a beta-spectrin, in primary biliary cirrhosis. Liver Int 2004;24:637-645.
    • (2004) Liver Int , vol.24 , pp. 637-645
    • Mishra, B.1    Tang, Y.2    Katuri, V.3    Fleury, T.4    Said, A.H.5    Rashid, A.6
  • 24
    • 35848951652 scopus 로고    scopus 로고
    • Disruption of transforming growth factor-beta signaling through beta-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation
    • Kitisin K, Ganesan N, Tang Y, Jogunoori W, Volpe EA, Kim SS, et al. Disruption of transforming growth factor-beta signaling through beta-spectrin ELF leads to hepatocellular cancer through cyclin D1 activation. Oncogene 2007;26:7103-7110.
    • (2007) Oncogene , vol.26 , pp. 7103-7110
    • Kitisin, K.1    Ganesan, N.2    Tang, Y.3    Jogunoori, W.4    Volpe, E.A.5    Kim, S.S.6
  • 25
    • 33748641755 scopus 로고    scopus 로고
    • Hyperplasia and spontaneous tumor development in the gynecologic system in mice lacking the BRCA1-Delta11 isoform
    • Kim SS, Cao L, Lim SC, Li C, Wang RH, Xu X, et al. Hyperplasia and spontaneous tumor development in the gynecologic system in mice lacking the BRCA1-Delta11 isoform. Mol Cell Biol 2006;26:6983-6992.
    • (2006) Mol Cell Biol , vol.26 , pp. 6983-6992
    • Kim, S.S.1    Cao, L.2    Lim, S.C.3    Li, C.4    Wang, R.H.5    Xu, X.6
  • 26
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 27
    • 0033552955 scopus 로고    scopus 로고
    • Elf3 encodes a novel 200-kD beta-spectrin: Role in liver development
    • Mishra L, Cai T, Yu P, Monga SP, Mishra B. Elf3 encodes a novel 200-kD beta-spectrin: Role in liver development. Oncogene 1999;18:353-364.
    • (1999) Oncogene , vol.18 , pp. 353-364
    • Mishra, L.1    Cai, T.2    Yu, P.3    Monga, S.P.4    Mishra, B.5
  • 28
    • 0034595635 scopus 로고    scopus 로고
    • Receptor chimeras indicate that the vascular endothelial growth factor receptor-1 (VEGFR-1) modulates mitogenic activity of VEGFR-2 in endothelial cells
    • Rahimi N, Dayanir V, Lashkari K. Receptor chimeras indicate that the vascular endothelial growth factor receptor-1 (VEGFR-1) modulates mitogenic activity of VEGFR-2 in endothelial cells. J Biol Chem 2000;275: 16986-16992.
    • (2000) J Biol Chem , vol.275 , pp. 16986-16992
    • Rahimi, N.1    Dayanir, V.2    Lashkari, K.3
  • 29
    • 0037326702 scopus 로고    scopus 로고
    • Signal transduction by vascular endothelial growth factor receptors
    • Claesson-Welsh L. Signal transduction by vascular endothelial growth factor receptors. Biochem Soc Trans 2003;31:20-24.
    • (2003) Biochem Soc Trans , vol.31 , pp. 20-24
    • Claesson-Welsh, L.1
  • 30
    • 0033381357 scopus 로고    scopus 로고
    • The role for transforming growth factor-beta (TGF-beta) in human cancer
    • Gold LI. The role for transforming growth factor-beta (TGF-beta) in human cancer. Crit Rev Oncog 1999;10:303-360.
    • (1999) Crit Rev Oncog , vol.10 , pp. 303-360
    • Gold, L.I.1
  • 31
    • 0034604110 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in human disease
    • Blobe GC, Schiemann WP, Lodish HF. Role of transforming growth factor beta in human disease. N Engl J Med 2000;342:1350-1358.
    • (2000) N Engl J Med , vol.342 , pp. 1350-1358
    • Blobe, G.C.1    Schiemann, W.P.2    Lodish, H.F.3
  • 33
    • 0037757793 scopus 로고    scopus 로고
    • Role of Smad4 (DPC4) inactivation in human cancer
    • Miyaki M, Kuroki T. Role of Smad4 (DPC4) inactivation in human cancer. Biochem Biophys Res Commun 2003;306:799-804.
    • (2003) Biochem Biophys Res Commun , vol.306 , pp. 799-804
    • Miyaki, M.1    Kuroki, T.2
  • 35
    • 20144378766 scopus 로고    scopus 로고
    • Transforming growth factor-beta suppresses nonmetastatic colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis
    • Tang Y, Katuri V, Srinivasan R, Fogt F, Redman R, Anand G, et al. Transforming growth factor-beta suppresses nonmetastatic colon cancer through Smad4 and adaptor protein ELF at an early stage of tumorigenesis. Cancer Res 2005;65:4228-4237.
    • (2005) Cancer Res , vol.65 , pp. 4228-4237
    • Tang, Y.1    Katuri, V.2    Srinivasan, R.3    Fogt, F.4    Redman, R.5    Anand, G.6
  • 36
    • 33645297918 scopus 로고    scopus 로고
    • Critical interactions between TGF-beta signaling/ELF, and E-cadherin/beta-catenin mediated tumor suppression
    • Katuri V, Tang Y, Li C, Jogunoori W, Deng CX, Rashid A, et al. Critical interactions between TGF-beta signaling/ELF, and E-cadherin/beta-catenin mediated tumor suppression. Oncogene 2006;25:1871-1886.
    • (2006) Oncogene , vol.25 , pp. 1871-1886
    • Katuri, V.1    Tang, Y.2    Li, C.3    Jogunoori, W.4    Deng, C.X.5    Rashid, A.6
  • 37
    • 22844440952 scopus 로고    scopus 로고
    • Inhibition of Smad antiproliferative function by CDK phosphorylation
    • Liu F, Matsuura I. Inhibition of Smad antiproliferative function by CDK phosphorylation. Cell Cycle 2005;4:63-66.
    • (2005) Cell Cycle , vol.4 , pp. 63-66
    • Liu, F.1    Matsuura, I.2
  • 38
    • 33646470279 scopus 로고    scopus 로고
    • TGF-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: Role of the beta-spectrin, ELF
    • Kim SS, Shetty K, Katuri V, Kitisin K, Baek HJ, Tang Y, et al. TGF-beta signaling pathway inactivation and cell cycle deregulation in the development of gastric cancer: Role of the beta-spectrin, ELF. Biochem Biophys Res Commun 2006;344:1216-1223.
    • (2006) Biochem Biophys Res Commun , vol.344 , pp. 1216-1223
    • Kim, S.S.1    Shetty, K.2    Katuri, V.3    Kitisin, K.4    Baek, H.J.5    Tang, Y.6
  • 39
    • 33745639683 scopus 로고    scopus 로고
    • Inactivation of TGF-beta signaling in lung cancer results in increased CDK4 activity that can be rescued by ELF
    • Baek HJ, Kim SS, da Silva FM, Volpe EA, Evans S, Mishra B, et al. Inactivation of TGF-beta signaling in lung cancer results in increased CDK4 activity that can be rescued by ELF. Biochem Biophys Res Commun 2006;346:1150-1157.
    • (2006) Biochem Biophys Res Commun , vol.346 , pp. 1150-1157
    • Baek, H.J.1    Kim, S.S.2    da Silva, F.M.3    Volpe, E.A.4    Evans, S.5    Mishra, B.6
  • 40
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • Folkman J. Angiogenesis in cancer, vascular, rheumatoid and other disease. Nat Med 1995;1:27-31.
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 41
    • 0025141337 scopus 로고
    • What is the evidence that tumors are angiogenesis dependent?
    • Folkman J. What is the evidence that tumors are angiogenesis dependent? J Natl Cancer Inst 1990;82:4-6.
    • (1990) J Natl Cancer Inst , vol.82 , pp. 4-6
    • Folkman, J.1
  • 43
    • 0030908887 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor in normal liver and hepatocellular carcinoma: An immunohistochemical study
    • Chow NH, Hsu PI, Lin XZ, Yang HB, Chan SH, Cheng KS, et al. Expression of vascular endothelial growth factor in normal liver and hepatocellular carcinoma: An immunohistochemical study. Hum Pathol 1997;28: 698-703.
    • (1997) Hum Pathol , vol.28 , pp. 698-703
    • Chow, N.H.1    Hsu, P.I.2    Lin, X.Z.3    Yang, H.B.4    Chan, S.H.5    Cheng, K.S.6
  • 44
    • 0030723789 scopus 로고    scopus 로고
    • Increased expression of vascular endothelial growth factor in human hepatocellular carcinoma
    • Miura H, Miyazaki T, Kuroda M, Oka T, Machinami R, Kodama T, et al. Increased expression of vascular endothelial growth factor in human hepatocellular carcinoma. J Hepatol 1997;27:854-861.
    • (1997) J Hepatol , vol.27 , pp. 854-861
    • Miura, H.1    Miyazaki, T.2    Kuroda, M.3    Oka, T.4    Machinami, R.5    Kodama, T.6
  • 45
  • 46
    • 0031778206 scopus 로고    scopus 로고
    • Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: Possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver
    • El-Assal ON, Yamanoi A, Soda Y, Yamaguchi M, Igarashi M, Yamamoto A, et al. Clinical significance of microvessel density and vascular endothelial growth factor expression in hepatocellular carcinoma and surrounding liver: Possible involvement of vascular endothelial growth factor in the angiogenesis of cirrhotic liver. HEPATOLOGY 1998;27:1554-1562.
    • (1998) HEPATOLOGY , vol.27 , pp. 1554-1562
    • El-Assal, O.N.1    Yamanoi, A.2    Soda, Y.3    Yamaguchi, M.4    Igarashi, M.5    Yamamoto, A.6
  • 47
    • 2542556259 scopus 로고    scopus 로고
    • Involvement of the vascular endothelial growth factor receptor-1 in murine hepatocellular carcinoma development
    • Yoshiji H, Kuriyama S, Yoshii J, Ikenaka Y, Noguchi R, Yanase K, et al. Involvement of the vascular endothelial growth factor receptor-1 in murine hepatocellular carcinoma development. J Hepatol 2004;41:97-103.
    • (2004) J Hepatol , vol.41 , pp. 97-103
    • Yoshiji, H.1    Kuriyama, S.2    Yoshii, J.3    Ikenaka, Y.4    Noguchi, R.5    Yanase, K.6
  • 48
    • 2542523903 scopus 로고    scopus 로고
    • Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice
    • Yoshiji H, Kuriyama S, Yoshii J, Ikenaka Y, Noguchi R, Hicklin DJ, et al. Halting the interaction between vascular endothelial growth factor and its receptors attenuates liver carcinogenesis in mice. HEPATOLOGY 2004;39: 1517-1524.
    • (2004) HEPATOLOGY , vol.39 , pp. 1517-1524
    • Yoshiji, H.1    Kuriyama, S.2    Yoshii, J.3    Ikenaka, Y.4    Noguchi, R.5    Hicklin, D.J.6
  • 49
    • 34548295317 scopus 로고    scopus 로고
    • Association between vascular endothelial growth factor gene polymorphisms and survival in hepatocellular carcinoma patients
    • Kong SY, Park JW, Lee JA, Park JE, Park KW, Hong EK, et al. Association between vascular endothelial growth factor gene polymorphisms and survival in hepatocellular carcinoma patients. HEPATOLOGY 2007;46:446-455.
    • (2007) HEPATOLOGY , vol.46 , pp. 446-455
    • Kong, S.Y.1    Park, J.W.2    Lee, J.A.3    Park, J.E.4    Park, K.W.5    Hong, E.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.