-
1
-
-
0022540321
-
CpG-rich islands and the function of DNA methylation
-
Bird AP. CpG-rich islands and the function of DNA methylation. Nature 1986, 321(6067):209-213.
-
(1986)
Nature
, vol.321
, Issue.6067
, pp. 209-213
-
-
Bird, A.P.1
-
2
-
-
31944432339
-
A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters
-
Saxonov S, Berg P, Brutlag DL. A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promoters. Proc Natl Acad Sci USA 2006, 103(5):1412-1417.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.5
, pp. 1412-1417
-
-
Saxonov, S.1
Berg, P.2
Brutlag, D.L.3
-
3
-
-
34248358308
-
Hyperconserved CpG domains underlie Polycombbinding sites
-
Tanay A, O'Donnell AH, Damelin M, Bestor TH. Hyperconserved CpG domains underlie Polycombbinding sites. Proc Natl Acad Sci USA 2007, 104(13):5521-5526.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.13
, pp. 5521-5526
-
-
Tanay, A.1
O'Donnell, A.H.2
Damelin, M.3
Bestor, T.H.4
-
4
-
-
33645777446
-
CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure
-
Bock C, Paulsen M, Tierling S, Mikeska T, Lengauer T, Walter J. CpG island methylation in human lymphocytes is highly correlated with DNA sequence, repeats, and predicted DNA structure. PLoS Genet 2006, 2(3):e26.
-
(2006)
PLoS Genet
, vol.2
, Issue.3
-
-
Bock, C.1
Paulsen, M.2
Tierling, S.3
Mikeska, T.4
Lengauer, T.5
Walter, J.6
-
5
-
-
34047116826
-
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
-
Weber M, Hellmann I, Stadler MB, Ramos L, Paabo S, Rebhan M, Schubeler D. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome. Nat Genet 2007, 39(4):457-466.
-
(2007)
Nat Genet
, vol.39
, Issue.4
, pp. 457-466
-
-
Weber, M.1
Hellmann, I.2
Stadler, M.B.3
Ramos, L.4
Paabo, S.5
Rebhan, M.6
Schubeler, D.7
-
6
-
-
0033615717
-
DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
-
Okano M, Bell DW, Haber DA, Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99(3):247-257.
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 247-257
-
-
Okano, M.1
Bell, D.W.2
Haber, D.A.3
Li, E.4
-
7
-
-
0026708177
-
Targeted mutation of the DNA methyltransferase gene results in embryonic lethality
-
Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992, 69(6):915-926.
-
(1992)
Cell
, vol.69
, Issue.6
, pp. 915-926
-
-
Li, E.1
Bestor, T.H.2
Jaenisch, R.3
-
8
-
-
0027378582
-
Role for DNA methylation in genomic imprinting
-
Li E, Beard C, Jaenisch R. Role for DNA methylation in genomic imprinting. Nature 1993, 366(6453):362-365.
-
(1993)
Nature
, vol.366
, Issue.6453
, pp. 362-365
-
-
Li, E.1
Beard, C.2
Jaenisch, R.3
-
9
-
-
0019510628
-
Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation
-
Mohandas T, Sparkes RS, Shapiro LJ, Reactivation of an inactive human X chromosome: evidence for X inactivation by DNA methylation. Science 1981, 211(4480):393-396.
-
(1981)
Science
, vol.211
, Issue.4480
, pp. 393-396
-
-
Mohandas, T.1
Sparkes, R.S.2
Shapiro, L.J.3
-
10
-
-
43749098985
-
DNA methylation landscapes: provocative insights from epigenomics
-
Suzuki MM, Bird A. DNA methylation landscapes: provocative insights from epigenomics. Nat Rev Genet 2008, 9(6):465-476.
-
(2008)
Nat Rev Genet
, vol.9
, Issue.6
, pp. 465-476
-
-
Suzuki, M.M.1
Bird, A.2
-
11
-
-
37249026814
-
Genome-wide analysis of DNA methylation patterns
-
Zilberman D, Henikoff S. Genome-wide analysis of DNA methylation patterns. Development 2007, 134(22):3959-3965.
-
(2007)
Development
, vol.134
, Issue.22
, pp. 3959-3965
-
-
Zilberman, D.1
Henikoff, S.2
-
12
-
-
40749109894
-
Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning
-
Cokus SJ, Feng S, Zhang X, Chen Z, Merriman B, Haudenschild CD, Pradhan S, Nelson SF, Pellegrini M, Jacobsen SE. Shotgun bisulphite sequencing of the Arabidopsis genome reveals DNA methylation patterning. Nature 2008, 452(7184):215-219.
-
(2008)
Nature
, vol.452
, Issue.7184
, pp. 215-219
-
-
Cokus, S.J.1
Feng, S.2
Zhang, X.3
Chen, Z.4
Merriman, B.5
Haudenschild, C.D.6
Pradhan, S.7
Nelson, S.F.8
Pellegrini, M.9
Jacobsen, S.E.10
-
13
-
-
42749087226
-
Highly integrated single-base resolution maps of the epigenome in Arabidopsis
-
Lister R, O'Malley RC, Tonti-Filippini J, Gregory BD, Berry CC, Millar AH, Ecker JR. Highly integrated single-base resolution maps of the epigenome in Arabidopsis. Cell 2008, 133(3):523-536.
-
(2008)
Cell
, vol.133
, Issue.3
, pp. 523-536
-
-
Lister, R.1
O'Malley, R.C.2
Tonti-Filippini, J.3
Gregory, B.D.4
Berry, C.C.5
Millar, A.H.6
Ecker, J.R.7
-
14
-
-
31744433660
-
Evidence for an instructive mechanism of de novo methylation in cancer cells
-
Keshet I, Schlesinger Y, Farkash S, Rand E, Hecht M, Segal E, Pikarski E, Young RA, Niveleau A, Cedar H, Simon I. Evidence for an instructive mechanism of de novo methylation in cancer cells. Nat Genet 2006, 38(2):149-153.
-
(2006)
Nat Genet
, vol.38
, Issue.2
, pp. 149-153
-
-
Keshet, I.1
Schlesinger, Y.2
Farkash, S.3
Rand, E.4
Hecht, M.5
Segal, E.6
Pikarski, E.7
Young, R.A.8
Niveleau, A.9
Cedar, H.10
Simon, I.11
-
15
-
-
64349091471
-
Targeted and genomescale strategies reveal gene-body methylation signatures in human cells
-
Ball MP, Li JB, Gao Y, Lee JH, LeProust EM, Park IH, Xie B, Daley GQ, Church GM. Targeted and genomescale strategies reveal gene-body methylation signatures in human cells. Nat Biotechnol 2009, 27(4):361-368.
-
(2009)
Nat Biotechnol
, vol.27
, Issue.4
, pp. 361-368
-
-
Ball, M.P.1
Li, J.B.2
Gao, Y.3
Lee, J.H.4
LeProust, E.M.5
Park, I.H.6
Xie, B.7
Daley, G.Q.8
Church, G.M.9
-
16
-
-
64349106730
-
Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming
-
Deng J, Shoemaker R, Xie B, Gore A, LeProust EM, Antosiewicz-Bourget J, Egli D, Maherali N, Park IH, Yu J, Daley GQ, Eggan K, Hochedlinger K, Thomson J, Wang W, Gao Y, Zhang K. Targeted bisulfite sequencing reveals changes in DNA methylation associated with nuclear reprogramming. Nat Biotechnol 2009, 27(4):353-360.
-
(2009)
Nat Biotechnol
, vol.27
, Issue.4
, pp. 353-360
-
-
Deng, J.1
Shoemaker, R.2
Xie, B.3
Gore, A.4
LeProust, E.M.5
Antosiewicz-Bourget, J.6
Egli, D.7
Maherali, N.8
Park, I.H.9
Yu, J.10
Daley, G.Q.11
Eggan, K.12
Hochedlinger, K.13
Thomson, J.14
Wang, W.15
Gao, Y.16
Zhang, K.17
-
17
-
-
0023216891
-
CpG islands in vertebrate genomes
-
Gardiner-Garden M, Frommer M. CpG islands in vertebrate genomes. J Mol Biol 1987, 196(2):261-282.
-
(1987)
J Mol Biol
, vol.196
, Issue.2
, pp. 261-282
-
-
Gardiner-Garden, M.1
Frommer, M.2
-
18
-
-
0035999991
-
CpGProD: identifying CpG islands associated with transcription start sites in large genomic mammalian sequences
-
Ponger L, Mouchiroud D. CpGProD: identifying CpG islands associated with transcription start sites in large genomic mammalian sequences. Bioinformatics 2002, 18(4):631-633.
-
(2002)
Bioinformatics
, vol.18
, Issue.4
, pp. 631-633
-
-
Ponger, L.1
Mouchiroud, D.2
-
19
-
-
38949212693
-
A novel CpG island set identifies tissue-specific methylation at developmental gene loci
-
Illingworth R, Kerr A, Desousa D, Jorgensen H, Ellis P, Stalker J, Jackson D, Clee C, Plumb R, Rogers J, Humphray S, Cox T, Langford C, Bird A. A novel CpG island set identifies tissue-specific methylation at developmental gene loci. PLoS Biol 2008, 6(1):e22.
-
(2008)
PLoS Biol
, vol.6
, Issue.1
-
-
Illingworth, R.1
Kerr, A.2
Desousa, D.3
Jorgensen, H.4
Ellis, P.5
Stalker, J.6
Jackson, D.7
Clee, C.8
Plumb, R.9
Rogers, J.10
Humphray, S.11
Cox, T.12
Langford, C.13
Bird, A.14
-
20
-
-
0037133565
-
Comprehensive analysis of CpG islands in human chromosomes 21 and 22
-
Takai D, Jones PA. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci USA 2002, 99(6):3740-3745.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, Issue.6
, pp. 3740-3745
-
-
Takai, D.1
Jones, P.A.2
-
21
-
-
0345603004
-
The CpG island searcher: a new WWW resource
-
Takai D, Jones PA. The CpG island searcher: a new WWW resource. Silico Biol 2003, 3(3):235-240.
-
(2003)
Silico Biol
, vol.3
, Issue.3
, pp. 235-240
-
-
Takai, D.1
Jones, P.A.2
-
22
-
-
34347337742
-
CpG island mapping by epigenome prediction
-
Bock C, Walter J, Paulsen M, Lengauer T. CpG island mapping by epigenome prediction. PLoS Comput Biol 2007, 3(6):e110.
-
(2007)
PLoS Comput Biol
, vol.3
, Issue.6
-
-
Bock, C.1
Walter, J.2
Paulsen, M.3
Lengauer, T.4
-
23
-
-
66149147557
-
Developmental programming of CpG island methylation profiles in the human genome
-
Straussman R, Nejman D, Roberts D, Steinfeld I, Blum B, Benvenisty N, Simon I, Yakhini Z, Cedar H. Developmental programming of CpG island methylation profiles in the human genome. Nat Struct Mol Biol 2009, 16(5):564-571.
-
(2009)
Nat Struct Mol Biol
, vol.16
, Issue.5
, pp. 564-571
-
-
Straussman, R.1
Nejman, D.2
Roberts, D.3
Steinfeld, I.4
Blum, B.5
Benvenisty, N.6
Simon, I.7
Yakhini, Z.8
Cedar, H.9
-
24
-
-
0026740497
-
Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line
-
Kafri T, Ariel M, Brandeis M, Shemer R, Urven L, McCarrey J, Cedar H, Razin A. Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line. Genes Dev 1992, 6(5):705-714.
-
(1992)
Genes Dev
, vol.6
, Issue.5
, pp. 705-714
-
-
Kafri, T.1
Ariel, M.2
Brandeis, M.3
Shemer, R.4
Urven, L.5
McCarrey, J.6
Cedar, H.7
Razin, A.8
-
25
-
-
33751505540
-
DNA methylation profiling of human chromosomes 6, 20 and 22
-
Eckhardt F, Lewin J, Cortese R, Rakyan VK, Attwood J, Burger M, Burton J, Cox TV, Davies R, Down TA, Haefliger C, Horton R, Howe K, Jackson DK, Kunde J, Koenig C, Liddle J, Niblett D, Otto T, Pettett R, Seemann S, Thompson C, West T, Rogers J, Olek A, Berlin K, Beck S. DNA methylation profiling of human chromosomes 6, 20 and 22. Nat Genet 2006, 38(12):1378-1385.
-
(2006)
Nat Genet
, vol.38
, Issue.12
, pp. 1378-1385
-
-
Eckhardt, F.1
Lewin, J.2
Cortese, R.3
Rakyan, V.K.4
Attwood, J.5
Burger, M.6
Burton, J.7
Cox, T.V.8
Davies, R.9
Down, T.A.10
Haefliger, C.11
Horton, R.12
Howe, K.13
Jackson, D.K.14
Kunde, J.15
Koenig, C.16
Liddle, J.17
Niblett, D.18
Otto, T.19
Pettett, R.20
Seemann, S.21
Thompson, C.22
West, T.23
Rogers, J.24
Olek, A.25
Berlin, K.26
Beck, S.27
more..
-
26
-
-
51649129596
-
Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors
-
Mohn F, Weber M, Rebhan M, Roloff TC, Richter J, Stadler MB, Bibel M, Schubeler D. Lineage-specific polycomb targets and de novo DNA methylation define restriction and potential of neuronal progenitors. Mol Cell 2008, 30(6):755-766.
-
(2008)
Mol Cell
, vol.30
, Issue.6
, pp. 755-766
-
-
Mohn, F.1
Weber, M.2
Rebhan, M.3
Roloff, T.C.4
Richter, J.5
Stadler, M.B.6
Bibel, M.7
Schubeler, D.8
-
27
-
-
58849091905
-
A human B cell methylome at 100-base pair resolution
-
Rauch TA, Wu X, Zhong X, Riggs AD, Pfeifer GP. A human B cell methylome at 100-base pair resolution. Proc Natl Acad Sci USA 2009, 106(3):671-678.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.3
, pp. 671-678
-
-
Rauch, T.A.1
Wu, X.2
Zhong, X.3
Riggs, A.D.4
Pfeifer, G.P.5
-
28
-
-
50649108994
-
An integrated resource for genomewide identification and analysis of human tissue-specific differentially methylated regions (tDMRs)
-
Rakyan VK, Down TA, Thorne NP, Flicek P, Kulesha E, Graf S, Tomazou EM, Backdahl L, Johnson N, Herberth M, Howe KL, Jackson DK, Miretti MM, Fiegler H, Marioni JC, Birney E, Hubbard TJ, Carter NP, Tavare S, Beck S. An integrated resource for genomewide identification and analysis of human tissue-specific differentially methylated regions (tDMRs). Genome Res 2008, 18(9):1518-1529.
-
(2008)
Genome Res
, vol.18
, Issue.9
, pp. 1518-1529
-
-
Rakyan, V.K.1
Down, T.A.2
Thorne, N.P.3
Flicek, P.4
Kulesha, E.5
Graf, S.6
Tomazou, E.M.7
Backdahl, L.8
Johnson, N.9
Herberth, M.10
Howe, K.L.11
Jackson, D.K.12
Miretti, M.M.13
Fiegler, H.14
Marioni, J.C.15
Birney, E.16
Hubbard, T.J.17
Carter, N.P.18
Tavare, S.19
Beck, S.20
more..
-
29
-
-
35948981875
-
Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters
-
Shen L, Kondo Y, Guo Y, Zhang J, Zhang L, Ahmed S, Shu J, Chen X, Waterland RA, Issa JP. Genome-wide profiling of DNA methylation reveals a class of normally methylated CpG island promoters. PLoS Genet 2007, 3(10):2023-2036.
-
(2007)
PLoS Genet
, vol.3
, Issue.10
, pp. 2023-2036
-
-
Shen, L.1
Kondo, Y.2
Guo, Y.3
Zhang, J.4
Zhang, L.5
Ahmed, S.6
Shu, J.7
Chen, X.8
Waterland, R.A.9
Issa, J.P.10
-
30
-
-
0028104109
-
Sp1 elements protect a CpG island from de novo methylation
-
Brandeis M, FrankD,Keshet I, Siegfried Z, Mendelsohn M, Nemes A, Temper V, Razin A, Cedar H. Sp1 elements protect a CpG island from de novo methylation. Nature 1994, 371(6496):435-438.
-
(1994)
Nature
, vol.371
, Issue.6496
, pp. 435-438
-
-
Brandeis, M.1
Frank, D.2
Keshet, I.3
Siegfried, Z.4
Mendelsohn, M.5
Nemes, A.6
Temper, V.7
Razin, A.8
Cedar, H.9
-
31
-
-
0027960055
-
Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island
-
Macleod D, Charlton J, Mullins J, Bird AP. Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev 1994, 8(19):2282-2292.
-
(1994)
Genes Dev
, vol.8
, Issue.19
, pp. 2282-2292
-
-
Macleod, D.1
Charlton, J.2
Mullins, J.3
Bird, A.P.4
-
32
-
-
0032992224
-
DNA methylation represses transcription in vivo
-
Siegfried Z, Eden S, Mendelsohn M, Feng X, Tsuberi BZ, Cedar H. DNA methylation represses transcription in vivo. Nat Genet 1999, 22(2):203-206.
-
(1999)
Nat Genet
, vol.22
, Issue.2
, pp. 203-206
-
-
Siegfried, Z.1
Eden, S.2
Mendelsohn, M.3
Feng, X.4
Tsuberi, B.Z.5
Cedar, H.6
-
33
-
-
49649125042
-
Genomescale DNA methylation maps of pluripotent and differentiated cells
-
Meissner A, Mikkelsen TS, Gu H, Wernig,M, Hanna J, Sivachenko A, Zhang X, Bernstein BE, Nusbaum C, Jaffe DB, Gnirke A, Jaenisch R, Lander ES. Genomescale DNA methylation maps of pluripotent and differentiated cells. Nature 2008, 454(7205):766-770.
-
(2008)
Nature
, vol.454
, Issue.7205
, pp. 766-770
-
-
Meissner, A.1
Mikkelsen, T.S.2
Gu, H.3
Wernig, M.4
Hanna, J.5
Sivachenko, A.6
Zhang, X.7
Bernstein, B.E.8
Nusbaum, C.9
Jaffe, D.B.10
Gnirke, A.11
Jaenisch, R.12
Lander, E.S.13
-
34
-
-
34547725157
-
DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
-
Ooi SK, Qiu C, Bernstein E, Li K, Jia D, Yang Z, Erdjument-Bromage H, Tempst P, Lin SP, Allis CD, Cheng X, Bestor TH. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature 2007, 448(7154):714-717.
-
(2007)
Nature
, vol.448
, Issue.7154
, pp. 714-717
-
-
Ooi, S.K.1
Qiu, C.2
Bernstein, E.3
Li, K.4
Jia, D.5
Yang, Z.6
Erdjument-Bromage, H.7
Tempst, P.8
Lin, S.P.9
Allis, C.D.10
Cheng, X.11
Bestor, T.H.12
-
35
-
-
45349086923
-
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes
-
Farthing CR, Ficz G, Ng RK, Chan CF, Andrews S, Dean W, Hemberger M, Reik W. Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes. PLoS Genet 2008, 4(6):e1000116.
-
(2008)
PLoS Genet
, vol.4
, Issue.6
-
-
Farthing, C.R.1
Ficz, G.2
Ng, R.K.3
Chan, C.F.4
Andrews, S.5
Dean, W.6
Hemberger, M.7
Reik, W.8
-
36
-
-
0025322399
-
Sex difference in methylation of single-copy genes in human meiotic germ cells: implications for X chromosome inactivation, parental imprinting, and origin of CpG mutations
-
Driscoll DJ, Migeon BR. Sex difference in methylation of single-copy genes in human meiotic germ cells: implications for X chromosome inactivation, parental imprinting, and origin of CpG mutations. Somat Cell Mol Genet 1990, 16(3):267-282.
-
(1990)
Somat Cell Mol Genet
, vol.16
, Issue.3
, pp. 267-282
-
-
Driscoll, D.J.1
Migeon, B.R.2
-
37
-
-
32344450824
-
Genomic DNA methylation: the mark and its mediators
-
Klose RJ, Bird AP. Genomic DNA methylation: the mark and its mediators. Trends Biochem Sci 2006, 31(2):89-97.
-
(2006)
Trends Biochem Sci
, vol.31
, Issue.2
, pp. 89-97
-
-
Klose, R.J.1
Bird, A.P.2
-
38
-
-
14644406272
-
Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping
-
Roh TY, Cuddapah S, Zhao K. Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping. Genes Dev 2005, 19(5):542-552.
-
(2005)
Genes Dev
, vol.19
, Issue.5
, pp. 542-552
-
-
Roh, T.Y.1
Cuddapah, S.2
Zhao, K.3
-
39
-
-
34547624303
-
Genome-wide maps of chromatin state in pluripotent and lineage-committed cells
-
Mikkelsen TS, Ku M, Jaffe DB, Issac B, Lieberman E, Giannoukos G, Alvarez P, Brockman W, Kim TK, Koche RP, Lee W, Mendenhall E, O'Donovan A, Presser A, Russ C, Xie X, Meissner A, Wernig M, Jaenisch R, Nusbaum C, Lander ES, Bernstein BE. Genome-wide maps of chromatin state in pluripotent and lineage-committed cells. Nature 2007, 448(7153):553-560.
-
(2007)
Nature
, vol.448
, Issue.7153
, pp. 553-560
-
-
Mikkelsen, T.S.1
Ku, M.2
Jaffe, D.B.3
Issac, B.4
Lieberman, E.5
Giannoukos, G.6
Alvarez, P.7
Brockman, W.8
Kim, T.K.9
Koche, R.P.10
Lee, W.11
Mendenhall, E.12
O'Donovan, A.13
Presser, A.14
Russ, C.15
Xie, X.16
Meissner, A.17
Wernig, M.18
Jaenisch, R.19
Nusbaum, C.20
Lander, E.S.21
Bernstein, B.E.22
more..
-
40
-
-
24344466882
-
DNA methylation and histone modifications: teaming up to silence genes
-
Fuks F. DNA methylation and histone modifications: teaming up to silence genes. Curr Opin Genet Dev 2005, 15(5):490-495.
-
(2005)
Curr Opin Genet Dev
, vol.15
, Issue.5
, pp. 490-495
-
-
Fuks, F.1
-
41
-
-
38649126918
-
Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation
-
Fouse SD, Shen Y, Pellegrini M, Cole S, Meissner A, Van Neste L, Jaenisch R, Fan G. Promoter CpG methylation contributes to ES cell gene regulation in parallel with Oct4/Nanog, PcG complex, and histone H3 K4/K27 trimethylation. Cell Stem Cell 2008, 2(2):160-169.
-
(2008)
Cell Stem Cell
, vol.2
, Issue.2
, pp. 160-169
-
-
Fouse, S.D.1
Shen, Y.2
Pellegrini, M.3
Cole, S.4
Meissner, A.5
Van Neste, L.6
Jaenisch, R.7
Fan, G.8
-
42
-
-
34249692514
-
Role of DNA methylation in stable gene repression
-
Lande-Diner L, Zhang J, Ben-Porath I, Amariglio N, Keshet I, Hecht M, Azuara V, Fisher AG, Rechavi G, Cedar H. Role of DNA methylation in stable gene repression. J Biol Chem 2007, 282(16):12194-12200.
-
(2007)
J Biol Chem
, vol.282
, Issue.16
, pp. 12194-12200
-
-
Lande-Diner, L.1
Zhang, J.2
Ben-Porath, I.3
Amariglio, N.4
Keshet, I.5
Hecht, M.6
Azuara, V.7
Fisher, A.G.8
Rechavi, G.9
Cedar, H.10
-
43
-
-
29244438472
-
CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex
-
Lee JH, Skalnik DG. CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. J Biol Chem 2005, 280(50):41725-41731.
-
(2005)
J Biol Chem
, vol.280
, Issue.50
, pp. 41725-41731
-
-
Lee, J.H.1
Skalnik, D.G.2
-
44
-
-
8644278033
-
Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein
-
Ayton PM, Chen EH, Cleary ML. Binding to nonmethylated CpG DNA is essential for target recognition, transactivation, and myeloid transformation by an MLL oncoprotein. Mol Cell Biol 2004, 24(23):10470-10478.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.23
, pp. 10470-10478
-
-
Ayton, P.M.1
Chen, E.H.2
Cleary, M.L.3
-
45
-
-
13944262010
-
Epigenetic ontogeny of the Igk locus during B cell development
-
Goldmit M, Ji Y, Skok J, Roldan E, Jung S, Cedar H, Bergman Y. Epigenetic ontogeny of the Igk locus during B cell development. Nat Immunol 2005, 6(2):198-203.
-
(2005)
Nat Immunol
, vol.6
, Issue.2
, pp. 198-203
-
-
Goldmit, M.1
Ji, Y.2
Skok, J.3
Roldan, E.4
Jung, S.5
Cedar, H.6
Bergman, Y.7
-
46
-
-
8844265508
-
Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins
-
Ringrose L, Paro R. Epigenetic regulation of cellular memory by the Polycomb and Trithorax group proteins. Annu Rev Genet 2004, 38:413-443.
-
(2004)
Annu Rev Genet
, vol.38
, pp. 413-443
-
-
Ringrose, L.1
Paro, R.2
-
47
-
-
15744396813
-
The key to development: interpreting the histone code?
-
Margueron R, Trojer P, Reinberg D. The key to development: interpreting the histone code? Curr Opin Genet Dev 2005, 15(2):163-176.
-
(2005)
Curr Opin Genet Dev
, vol.15
, Issue.2
, pp. 163-176
-
-
Margueron, R.1
Trojer, P.2
Reinberg, D.3
-
48
-
-
33646070846
-
A bivalent chromatin structure marks key developmental genes in embryonic stem cells
-
Bernstein BE, Mikkelsen TS, Xie X, KamalM, Huebert DJ, Cuff J, Fry B, Meissner A, Wernig M, Plath K, Jaenisch R, Wagschal A, Feil R, Schreiber SL, Lander ES. A bivalent chromatin structure marks key developmental genes in embryonic stem cells. Cell 2006, 125(2):315-326.
-
(2006)
Cell
, vol.125
, Issue.2
, pp. 315-326
-
-
Bernstein, B.E.1
Mikkelsen, T.S.2
Xie, X.3
Kamal, M.4
Huebert, D.J.5
Cuff, J.6
Fry, B.7
Meissner, A.8
Wernig, M.9
Plath, K.10
Jaenisch, R.11
Wagschal, A.12
Feil, R.13
Schreiber, S.L.14
Lander, E.S.15
-
49
-
-
32844459336
-
The Polycomb group protein EZH2 directly controls DNA methylation
-
Vire E, Brenner C, Deplus R, Blanchon L, Fraga M, Didelot C, Morey L, Van Eynde A, Bernard D, Vanderwinden JM, Bollen M, Esteller M, Di Croce L, de Launoit Y, Fuks F. The Polycomb group protein EZH2 directly controls DNA methylation. Nature 2006, 439(7078):871-874.
-
(2006)
Nature
, vol.439
, Issue.7078
, pp. 871-874
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
Blanchon, L.4
Fraga, M.5
Didelot, C.6
Morey, L.7
Van Eynde, A.8
Bernard, D.9
Vanderwinden, J.M.10
Bollen, M.11
Esteller, M.12
Di Croce, L.13
de Launoit, Y.14
Fuks, F.15
-
50
-
-
33846649587
-
Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer
-
Schlesinger Y, Straussman R, Keshet I, Farkash S, Hecht M, Zimmerman J, Eden E, Yakhini Z, Ben-Shushan E, Reubinoff BE, Bergman Y, Simon I, Cedar H. Polycomb-mediated methylation on Lys27 of histone H3 pre-marks genes for de novo methylation in cancer. Nat Genet 2007, 39(2):232-236.
-
(2007)
Nat Genet
, vol.39
, Issue.2
, pp. 232-236
-
-
Schlesinger, Y.1
Straussman, R.2
Keshet, I.3
Farkash, S.4
Hecht, M.5
Zimmerman, J.6
Eden, E.7
Yakhini, Z.8
Ben-Shushan, E.9
Reubinoff, B.E.10
Bergman, Y.11
Simon, I.12
Cedar, H.13
-
51
-
-
51349105905
-
Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
-
Gal-Yam EN, Egger G, Iniguez L, Holster H, Einarsson S, Zhang X, Lin JC, Liang G, Jones PA, Tanay A. Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line. Proc Natl Acad Sci USA 2008, 105(35):12979-12984.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, Issue.35
, pp. 12979-12984
-
-
Gal-Yam, E.N.1
Egger, G.2
Iniguez, L.3
Holster, H.4
Einarsson, S.5
Zhang, X.6
Lin, J.C.7
Liang, G.8
Jones, P.A.9
Tanay, A.10
-
52
-
-
33846569960
-
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
-
Ohm JE, McGarvey KM, Yu X, Cheng L, Schuebel KE, Cope L, Mohammad HP, Chen W, Daniel VC, Yu W, Berman DM, Jenuwein T, Pruitt K, Sharkis SJ,Watkins DN, Herman JG, Baylin SB. A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing. Nat Genet 2007, 39(2):237-242.
-
(2007)
Nat Genet
, vol.39
, Issue.2
, pp. 237-242
-
-
Ohm, J.E.1
McGarvey, K.M.2
Yu, X.3
Cheng, L.4
Schuebel, K.E.5
Cope, L.6
Mohammad, H.P.7
Chen, W.8
Daniel, V.C.9
Yu, W.10
Berman, D.M.11
Jenuwein, T.12
Pruitt, K.13
Sharkis, S.J.14
Watkins, D.N.15
Herman, J.G.16
Baylin, S.B.17
-
53
-
-
33846576622
-
Epigenetic stem cell signature in cancer
-
Widschwendter M, Fiegl H, Egle D, Mueller-Holzner E, Spizzo G, Marth C, Weisenberger DJ, Campan M, Young J, Jacobs I, Laird PW. Epigenetic stem cell signature in cancer. Nat Genet 2007, 39(2):157-158.
-
(2007)
Nat Genet
, vol.39
, Issue.2
, pp. 157-158
-
-
Widschwendter, M.1
Fiegl, H.2
Egle, D.3
Mueller-Holzner, E.4
Spizzo, G.5
Marth, C.6
Weisenberger, D.J.7
Campan, M.8
Young, J.9
Jacobs, I.10
Laird, P.W.11
-
54
-
-
22944489197
-
Silence of the genesmechanisms of long-term repression
-
Lande-Diner L, Cedar H. Silence of the genesmechanisms of long-term repression. Nat Rev Genet 2005, 6(8):648-654.
-
(2005)
Nat Rev Genet
, vol.6
, Issue.8
, pp. 648-654
-
-
Lande-Diner, L.1
Cedar, H.2
-
55
-
-
34447098370
-
A chromatin landmark and transcription initiation at most promoters in human cells
-
Guenther MG, Levine SS, Boyer LA, Jaenisch R, Young RA. A chromatin landmark and transcription initiation at most promoters in human cells. Cell 2007, 130(1):77-88.
-
(2007)
Cell
, vol.130
, Issue.1
, pp. 77-88
-
-
Guenther, M.G.1
Levine, S.S.2
Boyer, L.A.3
Jaenisch, R.4
Young, R.A.5
-
56
-
-
57849109058
-
Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters
-
Core LJ, Waterfall JJ, Lis JT. Nascent RNA sequencing reveals widespread pausing and divergent initiation at human promoters. Science 2008, 322(5909):1845-1848.
-
(2008)
Science
, vol.322
, Issue.5909
, pp. 1845-1848
-
-
Core, L.J.1
Waterfall, J.J.2
Lis, J.T.3
-
57
-
-
33748629119
-
Genome-wide high-resolution mapping and functional analysis of DNA methylation in arabidopsis
-
Zhang X, Yazaki J, Sundaresan A, Cokus S, Chan SW, Chen H, Henderson IR, Shinn P, Pellegrini M, Jacobsen SE, Ecker JR. Genome-wide high-resolution mapping and functional analysis of DNA methylation in arabidopsis. Cell 2006, 126(6):1189-1201.
-
(2006)
Cell
, vol.126
, Issue.6
, pp. 1189-1201
-
-
Zhang, X.1
Yazaki, J.2
Sundaresan, A.3
Cokus, S.4
Chan, S.W.5
Chen, H.6
Henderson, I.R.7
Shinn, P.8
Pellegrini, M.9
Jacobsen, S.E.10
Ecker, J.R.11
-
58
-
-
33845880624
-
Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription
-
Zilberman D, Gehring M, Tran RK, Ballinger T, Henikoff S. Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription. Nat Genet 2007, 39(1):61-69.
-
(2007)
Nat Genet
, vol.39
, Issue.1
, pp. 61-69
-
-
Zilberman, D.1
Gehring, M.2
Tran, R.K.3
Ballinger, T.4
Henikoff, S.5
-
59
-
-
33847304609
-
Gene body-specific methylation on the active X chromosome
-
Hellman A, Chess A. Gene body-specific methylation on the active X chromosome. Science 2007, 315(5815):1141-1143.
-
(2007)
Science
, vol.315
, Issue.5815
, pp. 1141-1143
-
-
Hellman, A.1
Chess, A.2
-
60
-
-
0028940587
-
Gene number, noise reduction and biological complexity
-
Bird AP. Gene number, noise reduction and biological complexity. Trends Genet 1995, 11(3):94-100.
-
(1995)
Trends Genet
, vol.11
, Issue.3
, pp. 94-100
-
-
Bird, A.P.1
-
61
-
-
34249275353
-
Phenotypic plasticity and the epigenetics of human disease
-
Feinberg AP. Phenotypic plasticity and the epigenetics of human disease. Nature 2007, 447(7143):433-440.
-
(2007)
Nature
, vol.447
, Issue.7143
, pp. 433-440
-
-
Feinberg, A.P.1
-
62
-
-
54949085778
-
Global reorganization of replication domains during embryonic stem cell differentiation
-
Hiratani I, Ryba T, Itoh M, Yokochi T, Schwaiger M, Chang CW, Lyou Y, Townes TM, Schubeler D, Gilbert DM. Global reorganization of replication domains during embryonic stem cell differentiation. PLoS Biol 2008, 6(10):e245.
-
(2008)
PLoS Biol
, vol.6
, Issue.10
-
-
Hiratani, I.1
Ryba, T.2
Itoh, M.3
Yokochi, T.4
Schwaiger, M.5
Chang, C.W.6
Lyou, Y.7
Townes, T.M.8
Schubeler, D.9
Gilbert, D.M.10
-
63
-
-
49649122472
-
American Association for Cancer Research Human Epigenome Task Force; European Union, Network of Excellence, Scientific Advisory Board.Moving AHEAD with an international human epigenome project
-
American Association for Cancer Research Human Epigenome Task Force; European Union, Network of Excellence, Scientific Advisory Board.Moving AHEAD with an international human epigenome project. Nature 2008, 454(7205): 711-715.
-
(2008)
Nature
, vol.454
, Issue.7205
, pp. 711-715
-
-
-
64
-
-
34249026300
-
High-resolution profiling of histone methylations in the human genome
-
Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, Wang Z, Wei G, Chepelev I, Zhao K. High-resolution profiling of histone methylations in the human genome. Cell 2007, 129(4): 823-837.
-
(2007)
Cell
, vol.129
, Issue.4
, pp. 823-837
-
-
Barski, A.1
Cuddapah, S.2
Cui, K.3
Roh, T.Y.4
Schones, D.E.5
Wang, Z.6
Wei, G.7
Chepelev, I.8
Zhao, K.9
-
66
-
-
34250633637
-
Cancer as a manifestation of aberrant chromatin structure
-
Brock MV, Herman JG, Baylin SB. Cancer as a manifestation of aberrant chromatin structure. Cancer J 2007, 13(1): 3-8.
-
(2007)
Cancer J
, vol.13
, Issue.1
, pp. 3-8
-
-
Brock, M.V.1
Herman, J.G.2
Baylin, S.B.3
-
67
-
-
33847065486
-
The epigenomics of cancer
-
Jones PA, Baylin SB. The epigenomics of cancer. Cell 2007, 128(4): 683-692
-
(2007)
Cell
, vol.128
, Issue.4
, pp. 683-692
-
-
Jones, P.A.1
Baylin, S.B.2
-
68
-
-
59749105927
-
Genome-wide high throughput analysis of DNA methylation in eukaryotes
-
Pomraning KR, Smith KM, Freitag M. Genome-wide high throughput analysis of DNA methylation in eukaryotes. Methods 2009, 47(2): 142-150.
-
(2009)
Methods
, vol.47
, Issue.2
, pp. 142-150
-
-
Pomraning, K.R.1
Smith, K.M.2
Freitag, M.3
-
69
-
-
46249112085
-
Combinatorial patterns of histone acetylations and methylations in the human genome
-
Wang Z, Zang C, Rosenfeld JA, Schones DE, Barski A, Cuddapah S, Cui K, Roh TY, Peng W, Zhang MQ, Zhao K. Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet 2008, 40(7): 897-903
-
(2008)
Nat Genet
, vol.40
, Issue.7
, pp. 897-903
-
-
Wang, Z.1
Zang, C.2
Rosenfeld, J.A.3
Schones, D.E.4
Barski, A.5
Cuddapah, S.6
Cui, K.7
Roh, T.Y.8
Peng, W.9
Zhang, M.Q.10
Zhao, K.11
|