Identification of diagnostic serum protein profiles of glioblastoma patients

Journal of Neuro-Oncology

Volumn 102, Issue 1, 2011, Pages 71-80

  Elstner, Anja ^a   Stockhammer, Florian ^a   Nguyen Dobinsky, Trong Nghia ^a   Nguyen, Quang Long ^a   Pilgermann, Ingo ^b   Gill, Amanjit ^a   Guhr, Anke ^c   Zhang, Tingguo ^d   Von Eckardstein, Kajetan ^e   Picht, Thomas ^a   Veelken, Julian ^f   Martuza, Robert L ^d   Von Deimling, Andreas ^g,i   Kurtz, Andreas ^a,h  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b Central Research Institute of Ambulatory Health Care in Germany   (Germany)

^c ROBERT KOCH INSTITUTE   (Germany)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^f Vivantes Klinikum   (Germany)

^g UNIVERSITY OF HEIDELBERG   (Germany)

^h Seoul National University   (South Korea)

ⁱ GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

Data mining; Glioblastoma; Serum marker proteins

Indexed keywords

BIOLOGICAL MARKER; BONE MORPHOGENETIC PROTEIN 2; CARBOPLATIN; CARMUSTINE; FATTY ACID BINDING PROTEIN; FATTY ACID BINDING PROTEIN 7; FRACTALKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; HEAT SHOCK PROTEIN 70; INTERLEUKIN 1ALPHA; LOMUSTINE; LYMPHOTOXIN; MIDKINE; PROCARBAZINE; RETINOL BINDING PROTEIN 4; SEROTONIN; SOMATOMEDIN BINDING PROTEIN 3; STEM CELL FACTOR; TEMOZOLOMIDE; THALIDOMIDE; THROMBOCYTE FACTOR 4; THROMBOSPONDIN 1; UNCLASSIFIED DRUG; VINCRISTINE;

ADULT; ARTICLE; ASTROCYTOMA; BRAIN TISSUE; CANCER PATIENT; CANCER SURVIVAL; CONTROLLED STUDY; CRANIOTOMY; DATA MINING; GENE EXPRESSION; GLIOBLASTOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN SECRETION; SENSITIVITY AND SPECIFICITY;

ADULT; AGED; BLOOD PROTEINS; BRAIN; BRAIN NEOPLASMS; CASE-CONTROL STUDIES; FEMALE; GLIOBLASTOMA; HUMANS; IMMUNOENZYME TECHNIQUES; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; PROGNOSIS; PROTEOMICS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 79952186124     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-010-0284-8     Document Type: Article

References (56)

1. Sallinen SL, Sallinen PK, Haapasalo HK et al (2000) Identification of differentially expressed genes in human gliomas by DNA microarray and tissue chip techniques. Cancer Res 60(23):6617-6622
2. Rickman DS, Bobek MP, Misek DE et al (2001) Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis. Cancer Res 61(18):6885-6891 (Pubitemid 32896514)
3. Fuller GN, Hess KR, Rhee CH et al (2002) Molecular classification of human diffuse gliomas by multidimensional scaling analysis of gene expression profiles parallels morphology-based classification, correlates with survival, and reveals clinically-relevant novel glioma subsets. Brain Pathol 12(1):108-116 (Pubitemid 33131367)
4. Nutt CL, Mani DR, Betensky RA et al (2003) Gene expression-based classification of malignant gliomas correlates better with survival than histological classification. Cancer Res 63(7):1602-1607 (Pubitemid 36373650)
5. Shai R, Shi T, Kremen TJ et al (2003) Gene expression profiling identifies molecular subtypes of gliomas. Oncogene 22(31):4918-4923 (Pubitemid 36981282)
6. van den Boom J, Wolter M, Kuick R et al (2003) Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction. Am J Pathol 163(3):1033-1043 (Pubitemid 37040139)
7. Liang Y, Diehn M, Watson N et al (2005) Gene expression profiling reveals molecularly and clinically distinct subtypes of glioblastoma multiforme. Proc Natl Acad Sci USA 102(16): 5814-5819 (Pubitemid 40559642)
8. Hess KR, Fuller GN, Rhee CH et al (2001) Statistical pattern analysis of gene expression profiles for glioblastoma tissues and cell lines. Int J Mol Med 8(2):183-188
9. Watson MA, Perry A, Budhraja V et al (2001) Gene expression profiling with oligonucleotide microarrays distinguishes World Health Organization grade of oligodendrogliomas. Cancer Res 61(5):1825-1829
10. Reddy SP, Britto R, Vinnakota K et al (2008) Novel glioblastoma markers with diagnostic and prognostic value identified through transcriptome analysis. Clin Cancer Res 14(10):2978-2987
11. Shirahata M, Iwao-Koizumi K, Saito S et al (2007) Gene expression-based molecular diagnostic system for malignant gliomas is superior to histological diagnosis. Clin Cancer Res 13(24):7341-7356
12. Furuta M, Weil RJ, Vortmeyer AO et al (2004) Protein patterns and proteins that identify subtypes of glioblastoma multiforme. Oncogene 23(40):6806-6814 (Pubitemid 39280012)
13. Iwadate Y, Sakaida T, Hiwasa T et al (2004) Molecular classification and survival prediction in human gliomas based on proteome analysis. Cancer Res 64(7):2496-2501 (Pubitemid 38523905)
14. Skog J, Würdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, Curry WT Jr, Carter BS, Krichevsky AM, Breakefield XO (2008) Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol 10(12):1470-1476
15. Welsh JB, Sapinoso LM, Kern SG et al (2003) Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum. Proc Natl Acad Sci USA 100(6):3410-3415 (Pubitemid 36356597)
16. Diehn M, Eisen MB, Botstein D et al (2000) Large-scale identification of secreted and membrane-associated gene products using DNA microarrays. Nat Genet 25(1):58-62 (Pubitemid 30257037)
17. Zhou W, Sokoll LJ, Bruzek DJ et al (1998) Identifying markers for pancreatic cancer by gene expression analysis. Cancer Epidemiol Biomarkers Prev 7(2):109-112 (Pubitemid 28109841)
18. Audero E, Cascone I, Zanon I et al (2001) Expression of angiopoietin-1 in human glioblastomas regulates tumor-induced angiogenesis: in vivo and in vitro studies. Arterioscler Thromb Vasc Biol 21(4):536-541 (Pubitemid 32323385)
19. Tanwar MK, Gilbert MR, Holland EC (2002) Gene expression microarray analysis reveals YKL-40 to be a potential serum marker for malignant character in human glioma. Cancer Res 62(15):4364-4368 (Pubitemid 34827294)
20. Streffer JR, Schuster M, Zipp F et al (1998) Soluble CD95 (Fas/APO-1) in malignant glioma: (no) implications for CD95-based immunotherapy? J Neurooncol 40(3):233-235
21. Krul ES, Tang J (1992) Secretion of apolipoprotein E by an astrocytoma cell line. J Neurosci Res 32(2):227-238
22. Koshikawa N, Nakamura T, Tsuchiya N et al (1996) Purification and identification of a novel and four known serine proteinase inhibitors secreted by human glioblastoma cells. J Biochem 119(2):334-339 (Pubitemid 26061531)
23. Roth W, Wild-Bode C, Platten M et al (2000) Secreted Frizzled-related proteins inhibit motility and promote growth of human malignant glioma cells. Oncogene 19(37):4210-4220
24. Mishima K, Asai A, Kadomatsu K et al (1997) Increased expression of midkine during the progression of human astrocytomas. Neurosci Lett 233(1):29-32 (Pubitemid 27402545)
25. Nano R, Capelli E, Argentina F et al (2003) Evaluation of serum levels of cytokines and intercellular adhesion molecule-1 (ICAM-1) in astrocytic tumours. Cell Mol Biol (Noisy-le-grand) 49(4):525-528
26. Salmaggi A, Eoli M, Frigerio S et al (1999) Circulating intercellular adhesion molecule-1 (ICAM-1), vascular cell adhesion molecule-1 (VCAM-1) and plasma thrombomodulin levels in glioblastoma patients. Cancer Lett 146(2):169-172 (Pubitemid 29492886)
27. Koga K, Todaka T, Morioka M et al (2001) Expression of angiopoietin-2 in human glioma cells and its role for angiogenesis. Cancer Res 61(16):6248-6254 (Pubitemid 32762564)
28. Fayyad JA, Jahshan CS, Karam EG (2001) Systems development of child mental health services in developing countries. Child Adolesc Psychiatr Clin N Am 10(4):745-762 (ix)
29. Kavsan V, Shostak K, Dmitrenko V et al (2005) Characterization of genes with increased expression in human glioblastomas. Tsitol Genet 39(6):37-49 (Pubitemid 46003921)
30. Freije WA, Castro-Vargas FE, Fang Z et al (2004) Gene expression profiling of gliomas strongly predicts survival. Cancer Res 64(18):6503-6510 (Pubitemid 39297907)
31. Ehtesham M, Yuan X, Kabos P et al (2004) Glioma tropic neural stem cells consist of astrocytic precursors and their migratory capacity is mediated by CXCR4. Neoplasia 6(3):287-293 (Pubitemid 38657085)
32. Kim JH, Skates SJ, Uede T et al (2002) Osteopontin as a potential diagnostic biomarker for ovarian cancer. JAMA 287(13):1671-1679 (Pubitemid 34289219)
33. Kononen J, Bubendorf L, Kallioniemi A et al (1998) Tissue microarrays for high-throughput molecular profiling of tumor specimens. Nat Med 4(7):844-847 (Pubitemid 28331029)
34. Webb G, Zhang S (2002) Beyond association rules: generalized rule discovery. Kluwer, Dordrecht
35. Webb G (1995) OPUS: an efficient admissible algorithm for unordered search. J Artif Intell Res 3:431-465
36. Doddi S, Marathe A, Ravi SS et al (2001) Discovery of association rules in medical data. Med Inform Internet Med 26(1):25-33 (Pubitemid 32547415)
37. Davidson AC, Hinkley DV (1997) Bootstrap methods and their application. Cambridge University Press, Cambridge
38. Johann DJ Jr, McGuigan MD, Patel AR et al (2004) Clinical proteomics and biomarker discovery. Ann N Y Acad Sci 1022: 295-305 (Pubitemid 38951617)
39. Bucca G, Carruba G, Saetta A et al (2004) Gene expression profiling of human cancers. Ann N Y Acad Sci 1028:28-37 (Pubitemid 40361807)
40. Naylor DJ, Hartl FU (2001) Contribution of molecular chaperones to protein folding in the cytoplasm of prokaryotic and eukaryotic cells. Biochem Soc Symp 68:45-68 (Pubitemid 33658552)
41. Kurtz A, Zimmer A, Schnutgen F et al (1994) The expression pattern of a novel gene encoding brain-fatty acid binding protein correlates with neuronal and glial cell development. Development 120(9):2637-2649 (Pubitemid 24268837)
42. Pockley AG, Georgiades A, Thulin T et al (2003) Serum heat shock protein 70 levels predict the development of atherosclerosis in subjects with established hypertension. Hypertension 42(3): 235-238 (Pubitemid 37093466)
43. Chan CP, Sanderson JE, Glatz JF et al (2004) A superior early myocardial infarction marker. Human heart-type fatty acid-binding protein. Z Kardiol 93(5):388-397
44. Chan KC, Lucas DA, Hise D et al (2004) Analysis of the human serum proteome. Clin Proteom 1(2):26
45. Adler MW, Rogers TJ (2005) Are chemokines the third major system in the brain? J Leukoc Biol 78(6):1204-1209
46. Angiolillo AL, Sgadari C, Taub DD et al (1995) Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo. J Exp Med 182(1):155-162
47. Strik HM, Weller M, Frank B et al (2000) Heat shock protein expression in human gliomas. Anticancer Res 20(6B):4457-4462 (Pubitemid 32141803)
48. Zhong L, Peng X, Hidalgo GE et al (2003) Antibodies to HSP70 and HSP90 in serum in non-small cell lung cancer patients. Cancer Detect Prev 27(4):285-290 (Pubitemid 36990247)
49. Chattopadhyay N, TFH J, Godbole MM et al (2004) Transforming growth factor beta receptor family ligands inhibit hepatocyte growth factor synthesis and secretion from astrocytoma cells. Brain Res Mol Brain Res 121(1-2):146-150 (Pubitemid 38224180)
50. Hallahan AR, Pritchard JI, Chandraratna RA et al (2003) BMP-2 mediates retinoid-induced apoptosis in medulloblastoma cells through a paracrine effect. Nat Med 9(8):1033-1038 (Pubitemid 37021783)
51. Yang S, Pham LK, Liao CP et al (2008) A novel bone morphogenetic protein signaling in heterotypic cell interactions in prostate cancer. Cancer Res 68(1):198-205 (Pubitemid 351380121)
52. Landry Y, Gies JP (2008) Drugs and their molecular targets: an updated overview. Fundam Clin Pharmacol 22(1):1-18 (Pubitemid 351171284)
53. Brem S, Tsanaclis AM, Gately S et al (1992) Immunolocalization of basic fibroblast growth factor to the microvasculature of human brain tumors. Cancer 70(11):2673-2680
54. Dudek AZ, Mahaseth H (2005) Circulating angiogenic cytokines in patients with advanced non-small cell lung cancer: correlation with treatment response and survival. Cancer Invest 23(3):193-200 (Pubitemid 40770736)
55. Brat DJ, Kaur B, Van Meir EG (2003) Genetic modulation of hypoxia induced gene expression and angiogenesis: relevance to brain tumors. Front Biosci 8:d100-d116 (Pubitemid 39069966)
56. Shen L, Dean NM, Glazer RI (1999) Induction of p53-dependent, insulin-like growth factor-binding protein-3-mediated apoptosis in glioblastoma multiforme cells by a protein kinase Calpha antisense oligonucleotide. Mol Pharmacol 55(2):396-402 (Pubitemid 29076038)