Analysis of the human serum proteome

Clinical Proteomics

Volumn 1, Issue 2, 2004, Pages 101-225

  Chan, King C ^a   Lucas, David A ^a   Hise, Denise ^b   Schaefer, Carl F ^b   Xiao, Zhen ^a   Janini, George M ^a   Buetow, Kenneth H ^b   Issaq, Haleem J ^a   Veenstra, Timothy D ^a   Conrads, Thomas P ^a  

^a SAIC FREDERICK INC   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Biomarker; Isoelectric focusing; Mass spectrometry; Multi dimensional separation; Proteomics; Serum

Indexed keywords

PLASMA PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CATION EXCHANGE; CELLULAR DISTRIBUTION; FRACTIONATION; HUMAN; ISOELECTRIC POINT; MICROCIRCULATION; MOLECULAR DYNAMICS; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEOMICS; REVERSED PHASE LIQUID CHROMATOGRAPHY; SIGNAL TRANSDUCTION; UNINDEXED SEQUENCE;

EID: 4344621315     PISSN: 15426416     EISSN: None     Source Type: Journal    
DOI: 10.1385/CP:1:2:101     Document Type: Article

References (16)

1. Aebersold R, Mann M. Mass spectrometry-based proteomics. Nature 2003;422:198-207.
2. Anderson NL, Anderson NG. The human plasma proteome: history, character, and diagnostic prospects. Mol Cell Proteomics 2002;1: 845-867.
3. Petricoin EF, Ardekani AM, Hitt BA, et al. Use of proteomic patterns in serum to identify ovarian cancer. Lancet 2002;359:572-577.
4. Conrads TP, Zhou M, Petricoin EF, 3rd, Liotta L, Veenstra TD. Cancer diagnosis using proteomic patterns. Expert Rev Mol Diagn 2003;3: 411-420.
5. Li J, Zhang Z, Rosenzweig J, Wang YY, Chan DW. Proteomics and bioinformatics approaches for identification of serum biomarkers to detect breast cancer. Clin Chem 2002;48:1296-1304.
6. Adam BL, Qu Y, Davis JW, et al. Serum protein fingerprinting coupled with a pattern-matching algorithm distinguishes prostate cancer from benign prostate hyperplasia and healthy men. Cancer Res 2002;62:3609-3614.
7. Petricoin EF, 3rd, Ornstein DK, Paweletz CP, et al. Serum proteomic patterns for detection of prostate cancer. J Natl Cancer Inst 2002;94: 1576-1578.
8. Adkins JN, Varnum SM, Auberry KJ, et al. Toward a human blood serum proteome: analysis by multidimensional separation coupled with mass spectrometry. Mol Cell Proteomics 2002;1:947-955.
9. Pieper R, Gatlin CL, Makusky AJ, et al. The human serum proteome: Display of nearly 3700 chromatographically separated protein spots on two-dimensional electrophoresis gels and identification of 325 distinct proteins. Proteomics 2003;3:1345-1364.
10. Tirumalai RS, Chan KC, Prieto DA, Issaq HJ, Conrads TP, Veenstra TD. Characterization of the low molecular weight human serum proteome. Mol Cell Proteomics 2003;2:1096-1103.
11. Washburn MP, Wolters D, Yates JR. Large-scale analysis of the yeast proteome by multi-dimensional protein identification technology. Nature Biotechnology 2001;19:242-247.
12. Grossklaus DJ, Smith JA, Shappell SB, Coffey CS, Chang SS, Cookson MS. The free/total prostate-specific antigen ratio (%fPSA) is the best predictor of tumor involvement in the radical prostatectomy specimen among men with an elevated PSA. Urol Oncol 2002;7:195-198.
13. Janini GM, Conrads TP, Veenstra TD, Issaq HJ. Development of a two-dimensional protein-peptide separation protocol for comprehensive proteome measurements. J Chromatogr B Analyt Technol Biomed Life Sci 2003;787: 43-51.
14. Yousef GM, Diamandis EP. The new human tissue kallikrein gene family: structure, function, and association to disease. Endocr Rev 2001;22:184-204.
15. Luo LY, Katsaros D, Scorilas A, et al. The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis. Cancer Res 2003;63:807-811.
16. Rumble B, Retallack R, Hilbich C, et al. Amyloid A4 protein and its precursor in Down's syndrome and Alzheimer's disease. N Engl J Med 1989;320:1446-1452.