Dual, constrictor-to-dilator, response of the mouse ductus arteriosus to the microsomal prostaglandin E synthase-1 inhibitor, 2-(6-chloro-1H- phenanthro[9,10d]imidazole- 2-yl)isophthalonitrile

Neonatology

Volumn 100, Issue 2, 2011, Pages 139-146

  Baragatti, Barbara ^a,b   Scebba, Francesca ^a   Sodini, Daria ^a   Pagni, Eleonora ^a   Ciofini, Enrica ^a   Xu, Daigen ^c   Coceani, Flavio ^a,b  

^a SCUOLA SUPERIORE SANT ANNA   (Italy)

^b INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^c MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

Cyclo oxygenase; Ductus arteriosus; Fetal and neonatal physiology; Nitric oxide; Nitric oxide synthase; Prostaglandin E synthase; Prostaglandin E 2

Indexed keywords

2 (6 CHLORO 1H PHENANTHRO[9,10 D]IMIDAZOLE 2 YL)ISOPHTHALONITRILE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MESSENGER RNA; MF 63; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTERY CONSTRICTION; ARTERY DILATATION; ARTICLE; DRUG BLOOD LEVEL; DUCTUS ARTERIOSUS; EX VIVO STUDY; FEMALE; FETUS; IN VIVO STUDY; ISOMETRICS; MOUSE; NEWBORN; NONHUMAN; POSTNATAL CARE; PRIORITY JOURNAL; PROTEIN EXPRESSION; UPREGULATION;

ANIMALS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DUCTUS ARTERIOSUS; DUCTUS ARTERIOSUS, PATENT; ENZYME INHIBITORS; FEMALE; GENE KNOCK-IN TECHNIQUES; HUMANS; IMIDAZOLES; INTRAMOLECULAR OXIDOREDUCTASES; MICE; MICE, INBRED C57BL; NITRIC OXIDE SYNTHASE TYPE III; PHENANTHRENES; PREGNANCY; VASOCONSTRICTION; VASODILATION;

MUS;

EID: 79952104524     PISSN: 16617800     EISSN: 16617819     Source Type: Journal    
DOI: 10.1159/000323790     Document Type: Article

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