Inhibition of cyclooxygenase isoforms in late- but not midgestation decreases contractility of the ductus arteriosus and prevents postnatal closure in mice

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 291, Issue 6, 2006, Pages

  Reese, Jeff ^a,c   Anderson, Judy D ^a   Brown, Naoko ^a   Roman, Christine ^b   Clyman, Ronald I ^b  

^a VANDERBILT UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Nonsteroidal anti inflammatory drugs; Patent ductus arteriosus

Indexed keywords

4 [5 (4 CHLOROPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOL 1 YL]BENZENESULFONAMIDE; 5 (4 CHLOROPHENYL) 1 (4 METHOXYPHENYL) 3 TRIFLUOROMETHYL 1H PYRAZOLE; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2 INHIBITOR; INDOMETACIN; OMEPRAZOLE; PROSTAGLANDIN SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DUCTUS ARTERIOSUS; EXPERIMENTAL MOUSE; FEMALE; GESTATION PERIOD; MOUSE; MUSCLE CONTRACTILITY; NONHUMAN; PREGNANCY DISORDER; PREMATURE LABOR; PRIORITY JOURNAL; SINGLE DRUG DOSE; UPREGULATION; UTERUS CONTRACTILITY; VASA VASORUM;

ANIMALS; ANIMALS, NEWBORN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE INHIBITORS; DUCTUS ARTERIOSUS; FEMALE; GESTATIONAL AGE; ISOENZYMES; MEMBRANE PROTEINS; MICE; PREGNANCY; PREGNANCY, ANIMAL; VASCULAR PATENCY; VASOCONSTRICTION;

EID: 33750596080     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00259.2006     Document Type: Article

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