Neurotensin receptor-2 and -3 are crucial for the anti-apoptotic effect of neurotensin on pancreatic β-TC3 cells

International Journal of Biochemistry and Cell Biology

Volumn 41, Issue 12, 2009, Pages 2398-2402

  Béraud Dufour, Sophie ^a   Coppola, Thierry ^a   Massa, Fabienne ^a   Mazella, Jean ^a  

^a CNRS   (France)

Author keywords

Apoptosis; Beta cell; Neurotensin; Receptor; Receptor complex

Indexed keywords

CASPASE 3; LEVOCABASTINE; NEUROTENSIN; NEUROTENSIN RECEPTOR; NEUROTENSIN RECEPTOR 2; SMALL INTERFERING RNA; SORTILIN; STAUROSPORINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL MEMBRANE; CELL PROTECTION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; IMMUNOPRECIPITATION; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; RAT;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; APOPTOSIS; CASPASE 3; CELL LINE; CYTOPROTECTION; INSULIN-SECRETING CELLS; MICE; NEUROTENSIN; PROTEIN BINDING; PROTEIN TRANSPORT; RECEPTORS, NEUROTENSIN; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STAUROSPORINE;

EID: 70350257957     PISSN: 13572725     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biocel.2009.04.002     Document Type: Article

References (18)

1. Bouvier M. Oligomerization of G-protein-coupled transmitter receptors. Nature Reviews: Neuroscience 2 (2001) 274-286
2. Coppola T., Beraud-Dufour S., Antoine A., Vincent J.P., and Mazella J. Neurotensin protects pancreatic beta cells from apoptosis. The International Journal of Biochemistry & Cell Biology 40 (2008) 2296-2302
3. da Costa C.A., Ancolio K., and Checler F. Wild-type but not Parkinson's disease-related ala-53 → Thr mutant alpha-synuclein protects neuronal cells from apoptotic stimuli. The Journal of Biological Chemistry 275 (2000) 24065-24069
4. Dolais-Kitabgi J., Kitabgi P., Brazeau P., and Freychet P. Effect of neurotensin on insulin, glucagon, and somatostatin release from isolated pancreatic islets. Endocrinology 105 (1979) 256-260
5. Leeman S.E., and Carraway R.E. Neurotensin: discovery, isolation, characterization, synthesis and possible physiological roles. Annals of the New York Academy of Sciences 400 (1982) 1-16
6. Maggio R., Novi F., Scarselli M., and Corsini G.U. The impact of G-protein-coupled receptor hetero-oligomerization on function and pharmacology. Febs Journal 272 (2005) 2939-2946
7. Martin S., Navarro V., Vincent J.P., and Mazella J. Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line. Gastroenterology 123 (2002) 1135-1143
8. Martin S., Vincent J.P., and Mazella J. Recycling ability of the mouse and the human neurotensin type 2 receptors depends on a single tyrosine residue. Journal of Cell Science 115 (2002) 165-173
9. Maudsley S., Pierce K.L., Zamah A.M., Miller W.E., Ahn S., Daaka Y., et al. The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. The Journal of Biological Chemistry 275 (2000) 9572-9580
10. Mazella J., and Vincent J.P. Functional roles of the NTS2 and NTS3 receptors. Peptides 27 (2006) 2469-2475
11. Morinville A., Martin S., Lavallee M., Vincent J.P., Beaudet A., and Mazella J. Internalization and trafficking of neurotensin via NTS3 receptors in HT29 cells. The International Journal of Biochemistry & Cell Biology 36 (2004) 2153-2168
12. Nykjaer A., Lee R., Teng K.K., Jansen P., Madsen P., Nielsen M.S., et al. Sortilin is essential for proNGF-induced neuronal cell death. Nature 427 (2004) 843-848
13. Petersen C.M., Nielsen M.S., Nykjaer A., Jacobsen L., Tommerup N., Rasmussen H.H., et al. Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography. The Journal of Biological Chemistry 272 (1997) 3599-3605
14. Pissios P., Ozcan U., Kokkotou E., Okada T., Liew C.W., Liu S., et al. Melanin concentrating hormone is a novel regulator of islet function and growth. Diabetes 56 (2007) 311-319
15. Sarret P., Krzywkowski P., Segal L., Nielsen M.S., Petersen C.M., Mazella J., et al. Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system. Journal of Comparative Neurology 461 (2003) 483-505
16. Sarret P., Perron A., Stroh T., and Beaudet A. Immunohistochemical distribution of NTS2 neurotensin receptors in the rat central nervous system. Journal of Comparative Neurology 461 (2003) 520-538
17. Shi J., and Kandror K.V. Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes. Developmental Cell 9 (2005) 99-108
18. Terrillon S., and Bouvier M. Roles of G-protein-coupled receptor dimerization. EMBO Reports 5 (2004) 30-34