-
1
-
-
0037306308
-
+ channels
-
DOI 10.1016/S0079-6107(02)00053-6, PII S0079610702000536
-
Seino S, Mikit T. Physiological and pathophysiological roles of ATP-sensitive K+ channels. Prog Biophys Mol Biol 2003;81:133-76 (Pubitemid 36141258)
-
(2003)
Progress in Biophysics and Molecular Biology
, vol.81
, Issue.2
, pp. 133-176
-
-
Seino, S.1
Miki, T.2
-
2
-
-
20644438226
-
KATP channel therapeutics at the bedside
-
Jahangir A, Terzic A. KATP channel therapeutics at the bedside J Mol Cell Cardiol 2005;39(1):99-112
-
(2005)
J. Mol. Cell Cardiol.
, vol.39
, Issue.1
, pp. 99-112
-
-
Jahangir, A.1
Terzic, A.2
-
3
-
-
0033037098
-
ATP-sensitive potassium channels: A model of heteromultimeric potassium channel/receptor assemblies
-
DOI 10.1146/annurev.physiol.61.1.337
-
Seino S. ATP-sensitive potassium channels: a model of heteromultimeric potassium channel/receptor assemblies. Annu Rev Physiol 1999;61:337-62 (Pubitemid 29143174)
-
(1999)
Annual Review of Physiology
, vol.61
, pp. 337-362
-
-
Seino, S.1
-
4
-
-
0029071861
-
Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic beta-cells and in the brain
-
Bond CT, Ammala C, Ashfield R, et al Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic beta-cells and in the brain. FEBS Letter 1995;367(1):61-6
-
(1995)
FEBS Letter
, vol.367
, Issue.1
, pp. 61-66
-
-
Bond, C.T.1
Ammala, C.2
Ashfield, R.3
-
5
-
-
0030996141
-
Association and stoichiometry of K(ATP) channel subunits
-
DOI 10.1016/S0896-6273(00)80321-9
-
Clement JP, Kunjilwar K, Gonzalez G, et al Association and stoichiometry of K (ATP) channel subunits. Neuron 1997;18(5):827-38 (Pubitemid 27232792)
-
(1997)
Neuron
, vol.18
, Issue.5
, pp. 827-838
-
-
Clement IV, J.P.1
Kunjilwar, K.2
Gonzalez, G.3
Schwanstecher, M.4
Panten, U.5
Aguilar-Bryan, L.6
Bryan, J.7
-
7
-
-
0029898253
-
+ channels
-
DOI 10.1016/S0896-6273(00)80124-5
-
Inagaki N, Gonoi T, Clement JP, et al A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels. Neuron 1996;16(5):1011-7 (Pubitemid 26171205)
-
(1996)
Neuron
, vol.16
, Issue.5
, pp. 1011-1017
-
-
Inagaki, N.1
Gonoi, T.2
Clement IV, J.P.3
Wang, C.-Z.4
Aguilar-Bryan, L.5
Bryan, J.6
Seino, S.7
-
8
-
-
0029743412
-
+ channel
-
DOI 10.1074/jbc.271.40.24321
-
Isomoto S, Kondo C, Yamada M, et al A novel sulphonylurea receptor forms with BIR (Kir6.2) a smooth muscle type ATP-sensitive K+ channel. J Biol Chem 1996;271(40):24321-4 (Pubitemid 26333158)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.40
, pp. 24321-24324
-
-
Isomoto, S.1
Kondo, C.2
Yamada, M.3
Matsumoto, S.4
Higashiguchi, O.5
Horio, Y.6
Matsuzawa, Y.7
Kurachi, Y.8
-
9
-
-
0029924673
-
Two types of ATP-sensitive potassium channels in rat portal vein smooth muscle cells
-
Zhang HL, Bolton TB. Two types of ATP-sensitive potassium channels in rat portal vein smooth muscle cells. Br J Pharmacol 1996;118:105-14 (Pubitemid 26131253)
-
(1996)
British Journal of Pharmacology
, vol.118
, Issue.1
, pp. 105-114
-
-
Zhang, H.-L.1
Bolton, T.B.2
-
10
-
-
0025913049
-
+ channel in the mitochondrial inner membrane
-
Inoue I, Nagase H, Kishi K, Higuti T. ATP-sensitive K+ channel in the mitochondrial inner membrane. Nature 1991;352:244-47 (Pubitemid 21912326)
-
(1991)
Nature
, vol.352
, Issue.6332
, pp. 244-247
-
-
Inoue, I.1
Nagase, H.2
Kishi, K.3
Higuti, T.4
-
11
-
-
0027051287
-
+ channel from rat liver and beef heart mitochondria
-
Paucek P, Mironova G, Mahdi E, et al Reconstruction and partial purification of the glibenclamide-sensitive, ATP-dependent K+ channel from rat liver and beef heart mitochondria. J Biol Chem 1992;267:26062-69 (Pubitemid 23014017)
-
(1992)
Journal of Biological Chemistry
, vol.267
, Issue.36
, pp. 26062-26069
-
-
Paucek, P.1
Mironova, G.2
Mahdi, F.3
Beavis, A.D.4
Woldegiorgis, G.5
Garlid, K.D.6
-
12
-
-
0035823614
-
Identyfication and properties of a novel intracellular mitochondrial ATP-sensitive potassium channel in brain
-
Bajgar R, Seetharaman S, Kowaltowski AJ, et al Identyfication and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain. J Biol Chem 2001;276:33369-74
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33369-33374
-
-
Bajgar, R.1
Seetharaman, S.2
Kowaltowski, A.J.3
-
14
-
-
0037010861
-
Opening of potassium channels modulates mitochondrial function in rat skeletal muscle
-
DOI 10.1016/S0005-2728(02)00340-7, PII S0005272802003407
-
Debska G, Kicinska A, Skalska J, et al Opening of potassium channels modulates mitochondrial function in rat skeletal muscle. Biochim Biophys Acta 2002;1556:97-105 (Pubitemid 35379667)
-
(2002)
Biochimica et Biophysica Acta - Bioenergetics
, vol.1556
, Issue.2-3
, pp. 97-105
-
-
Debska, G.1
Kicinska, A.2
Skalska, J.3
Szewczyk, A.4
May, R.5
Elger, C.E.6
Kunz, W.S.7
-
15
-
-
0024539763
-
The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism
-
Halestrap AP. The regulation of the matrix volume of mammalian mitochondria in vivo and in vitro and its role in the control of mitochondrial metabolism. Biochim Biophys Acta 1989;973:355-82 (Pubitemid 19073722)
-
(1989)
Biochimica et Biophysica Acta - Bioenergetics
, vol.973
, Issue.3
, pp. 355-382
-
-
Halestrap, A.P.1
-
16
-
-
0021741559
-
Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells
-
DOI 10.1038/312446a0
-
Ashcroft FM, Harrison DE, Ashcroft SJ. Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells. Nature 1984;312:446-8 (Pubitemid 15217837)
-
(1984)
Nature
, vol.312
, Issue.5993
, pp. 446-448
-
-
Ashcroft, F.M.1
Harrison, D.E.2
Ashcroft, S.J.H.3
-
18
-
-
0034325296
-
Regulation of glucagons release in mouse-cells by KATP channels and inactivation of TTX-sensitive Na+ channels
-
Gopel SO. Regulation of glucagons release in mouse-cells by KATP channels and inactivation of TTX-sensitive Na+ Channels. J Physiol 2000;528:509-20
-
(2000)
J. Physiol.
, vol.528
, pp. 509-520
-
-
Gopel, S.O.1
-
19
-
-
0034325594
-
Patch-clamp characterization of somatostatin-secreting - Cells in intact mouse pancreatic islets
-
Gopel SO, Kanno T, Barg S, Rorsman P. Patch-clamp characterization of somatostatin-secreting - cells in intact mouse pancreatic islets. J Physiol 2000;528:497-507
-
(2000)
J. Physiol.
, vol.528
, pp. 497-507
-
-
Gopel, S.O.1
Kanno, T.2
Barg, S.3
Rorsman, P.4
-
20
-
-
35148847369
-
Beta-cell hyperexcitability: From hyperinsulinism to diabetes
-
Nichols CG, Koster JC, Remedi MS. beta-cell hyperexcitability: from hyperinsulinism to diabetes. Diabetes Obes Metab 2007;9(Suppl 2):81-8
-
(2007)
Diabetes Obes Metab
, vol.9
, Issue.2
, pp. 81-88
-
-
Nichols, C.G.1
Koster, J.C.2
Remedi, M.S.3
-
21
-
-
23644442552
-
ATP-sensitive potassium channelopathies: Focus on insulin secretion
-
DOI 10.1172/JCI25495
-
Ashcroft FM, ATP-sensitive potassium channelopathies. focus on insulin secretion. J Clin Invest 2005;115:2047-58 (Pubitemid 41134141)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.8
, pp. 2047-2058
-
-
Ashcroft, F.M.1
-
22
-
-
0347359228
-
Hyperinsulinism in Infancy: From Basic Science to Clinical Disease
-
DOI 10.1152/physrev.00022.2003
-
Dunne MJ, Cosgrove KE, Shepherd RM,et al Hyperinsulinism in infancy: from basic science to clinical disease. Physiol Rev 2004;84(1):239-75 (Pubitemid 38049881)
-
(2004)
Physiological Reviews
, vol.84
, Issue.1
, pp. 239-275
-
-
Dunne, M.J.1
Cosgrove, K.E.2
Shepherd, R.M.3
Aynsley-Green, A.4
Lindley, K.J.5
-
23
-
-
0032751084
-
Channelopathies of inwardly rectifying potassium channels
-
Abraham MR, Jahangir A, Alekseev AE, Terzic A. Channelopathies of inwardly rectifying potassium channels. FASEB J 1999;13(14):1901-10 (Pubitemid 29517620)
-
(1999)
FASEB Journal
, vol.13
, Issue.14
, pp. 1901-1910
-
-
Abraham, M.R.1
Jahangir, A.2
Alekseev, A.E.3
Terzic, A.4
-
24
-
-
33846537882
-
Selective pancreatic ATP-sensitive potassium channel openers for the treatment of glucose homeostasis disorders
-
DOI 10.1358/dof.2006.031.11.1036837
-
De Tullio P, Lebrun P, Florence X, et al Selective pancreatic ATP-sensitive-potassium channel openers for the treatment of glucose homeostasis disorder. Drugs Fut 2006;31:991-1001 (Pubitemid 46165992)
-
(2006)
Drugs of the Future
, vol.31
, Issue.11
, pp. 991-1001
-
-
De Tullio, P.1
Lebrun, P.2
Florence, X.3
Antoine, M.-H.4
Francotte, P.5
Pirotte, B.6
-
25
-
-
33645824084
-
Physiological roles of ATP-sensitive K+ channels in smooth muscle
-
Pt 3
-
Teramoto N. Physiological roles of ATP-sensitive K+ channels in smooth muscle. J Physiol 2006;572(Pt 3):617-24
-
(2006)
J. Physiol.
, vol.572
, pp. 617-624
-
-
Teramoto, N.1
-
26
-
-
0036796478
-
Expression of mRNA transcripts for ATP-sensitive potassium channels in human myometrium
-
Curley M, Cairns MT, Friel AM, et al Expression of mRNA transcripts for ATP-sensitive potassium channels in human myometrium. Mol Hum Reprod 2002;8:941-5 (Pubitemid 35174929)
-
(2002)
Molecular Human Reproduction
, vol.8
, Issue.10
, pp. 941-945
-
-
Curley, M.1
Cairns, M.T.2
Friel, A.M.3
McMeel, O.M.4
Morrison, J.J.5
Smith, T.J.6
-
27
-
-
0042324046
-
ATP channel in human corporal smooth muscle cells
-
DOI 10.1038/sj.ijir.3901013
-
Insuk SO, Chae MR, Choi JW, et al Molecular basis and characteristics of KATP channel in human corporal smooth muscle cells. Int J Impot Res 2003;15(4):258-66 (Pubitemid 37101659)
-
(2003)
International Journal of Impotence Research
, vol.15
, Issue.4
, pp. 258-266
-
-
Insuk, S.O.1
Chae, M.R.2
Choi, J.W.3
Yang, D.K.4
Sim, J.H.5
Lee, S.W.6
-
28
-
-
33644780094
-
ATP channels reduces contractility of human prostate tissue
-
DOI 10.1002/pros.20355
-
Haynes JM, Cook AL. Protein kinase G-induced activation of K(ATP) channels reduces contractility of human prostate tissue. Prostate 2006;66:377-85 (Pubitemid 43346948)
-
(2006)
Prostate
, vol.66
, Issue.4
, pp. 377-385
-
-
Haynes, J.M.1
Cook, A.-L.M.2
-
29
-
-
0025103305
-
Modulation of ATP-sensitive K+ channels in skeletal muscle by intracellular protons
-
Davies NW. Modulation of ATP-sensitive K+ channels in skeletal muscle by intracellular protons. Nature 1990;343(6256):375-7
-
(1990)
Nature
, vol.343
, Issue.6256
, pp. 375-377
-
-
Davies, N.W.1
-
30
-
-
1642423664
-
+ channel opener, KCO912, on baseline and allergen induced airway hyperresponsiveness in allergic rabbits
-
DOI 10.1016/j.ejphar.2003.11.018
-
El-Hashim AZ, Buchheit KH, Fozard J, Page C. Effect of the K+(ATP) channel opener, KCO912, on baseline and allergen induced airway hyperresponsiveness in allergic rabbits. Eur J Pharmacol 2004;484(2-3):351-6 (Pubitemid 38117229)
-
(2004)
European Journal of Pharmacology
, vol.484
, Issue.2-3
, pp. 351-356
-
-
El-Hashim, A.Z.1
Buchheit, K.H.2
Fozard, J.3
Page, C.4
-
31
-
-
0037126931
-
Potential role of potassium channel openers in the treatment of asthma and chronic obstructive pulmonary disease
-
DOI 10.1016/S0024-3205(01)01487-4, PII S0024320501014874
-
Pelaia G, Gallelli L, Vatrella A, et al Potential role of potassium channel openers in the treatment of asthma and chronic obstructive pulmonary disease. Life Sci 2002;70(9):977-90 (Pubitemid 34085090)
-
(2002)
Life Sciences
, vol.70
, Issue.9
, pp. 977-990
-
-
Pelaia, G.1
Gallelli, L.2
Vatrella, A.3
Grembiale, R.D.4
Maselli, R.5
De Sarro, G.B.6
Marsico, S.A.7
-
32
-
-
0031896459
-
Neuroregulation of mucus secretion by opioid receptors and K(ATP) and BK(Ca) channels in ferret trachea in vitro
-
DOI 10.1038/sj.bjp.0701786
-
Ramnarine SI, Liu YC, Rogers DF. Neuroregulation of mucus secretion by opioid receptors and K(ATP) and BK (Ca) channels in ferret trachea in vitro. Br J Pharmacol 1998;123(8):1631-8 (Pubitemid 28182046)
-
(1998)
British Journal of Pharmacology
, vol.123
, Issue.8
, pp. 1631-1638
-
-
Ramnarine, S.I.1
Liu, Y.-C.2
Rogers, D.F.3
-
33
-
-
3042637079
-
Urinary bladder contraction and relaxation: Physiology and pathophysiology
-
DOI 10.1152/physrev.00038.2003
-
Andersson KE, Arner A. Urinary bladder contraction and relaxation: physiology and pathophysiology. Physiol Rev 2004;84:935-86 (Pubitemid 38823771)
-
(2004)
Physiological Reviews
, vol.84
, Issue.3
, pp. 935-986
-
-
Andersson, K.-E.1
Arner, A.2
-
34
-
-
4644244821
-
Potassium channel subtypes as molecular targets for overactive bladder and other urological disorders
-
DOI 10.1517/14728222.8.5.437
-
Gopalakrishnan M, Shieh CC, Potassium channel subtypes as molecular targets for overactive bladder and other urological disorders. Exp Opin Ther Targets 2004;8:437-58 (Pubitemid 39359650)
-
(2004)
Expert Opinion on Therapeutic Targets
, vol.8
, Issue.5
, pp. 437-458
-
-
Gopalakrishnan, M.1
Shieh, C.-C.2
-
35
-
-
0021086270
-
ATP-regulated K+ channels in cardiac muscle
-
Noma A. ATP-regulated K+ channels in cardiac muscle. Nature 1983;305:147-8
-
(1983)
Nature
, vol.305
, pp. 147-148
-
-
Noma, A.1
-
36
-
-
0033837022
-
ATP-sensitive potassium channels: A review of their cardioprotective pharmacology
-
DOI 10.1006/jmcc.2000.1111
-
Grover GJ, Garlid KD. ATP-sensitive potassium channels: a review of their cardioprotective pharmacology. J Mol Cell Cardiol 2000;32:677-95 (Pubitemid 30658936)
-
(2000)
Journal of Molecular and Cellular Cardiology
, vol.32
, Issue.4
, pp. 677-695
-
-
Grover, G.J.1
Garlid, K.D.2
-
37
-
-
19444367728
-
ATP channels in health and disease
-
DOI 10.1016/j.yjmcc.2005.02.026, PII S0022282805000751
-
Kane GC, Liu XK, Yamada S, et al Cardiac KATP channels in health and disease. J Mol Cell Cardiol 2005;38(6):937-43 (Pubitemid 40725941)
-
(2005)
Journal of Molecular and Cellular Cardiology
, vol.38
, Issue.6
, pp. 937-943
-
-
Kane, G.C.1
Liu, X.-K.2
Yamada, S.3
Olson, T.M.4
Terzic, A.5
-
38
-
-
0030700216
-
+ currents in rat arterial smooth muscle cells through protein kinase C
-
DOI 10.1111/j.1469-7793.1997.489bg.x
-
Kubo M, Quayle JM, Standen NB. Angiotensin II inhibition of ATP-sensitive K+ currents in rat arterial smooth muscle cells through protein kinase C. J Physiol 1997;503(Pt 3):489-96 (Pubitemid 27496663)
-
(1997)
Journal of Physiology
, vol.503
, Issue.3
, pp. 489-496
-
-
Kubo, M.1
Quayle, J.M.2
Standen, N.B.3
-
39
-
-
12144290256
-
ATP channel gating
-
DOI 10.1038/ng1329
-
Bienengraeber M, Olson TM, Selivanov VA, et al ABCC9 mutations identified in human dilated cardiomyopathy disrupt catalytic KATP channel gating. Nat Genet 2004;36(4):382-7 (Pubitemid 38437261)
-
(2004)
Nature Genetics
, vol.36
, Issue.4
, pp. 382-387
-
-
Bienengraeber, M.1
Olson, T.M.2
Selivanov, V.A.3
Kathmann, E.C.4
O'Cochlain, F.5
Gao, F.6
Karger, A.B.7
Ballew, J.D.8
Hodgson, D.M.9
Zingman, L.V.10
Pang, Y.-P.11
Alekseev, A.E.12
Terzic, A.13
-
40
-
-
33644800715
-
Effects of the blockade of cardiac sarcolemmal ATP-sensitive potassium channels on arrhythmias and coronary flow in ischemia-reperfusion model in isolated rat hearts
-
DOI 10.1016/j.vph.2005.11.006, PII S1537189105002582
-
Gok S, Vural K, Sekuri C, et al Effects of the blockade of cardiac sarcolemmal ATP-sensitive potassium channels on arrhythmias and coronary flow in ischaemia-reperfusion model in isolated rat hearts. Vascul Pharmacol 2006;44(4):197-205 (Pubitemid 43351178)
-
(2006)
Vascular Pharmacology
, vol.44
, Issue.4
, pp. 197-205
-
-
Gok, S.1
Vural, K.2
Sekuri, C.3
Onur, R.4
Tezcan, A.5
Izanli, A.6
-
41
-
-
29344475165
-
+ channels
-
DOI 10.1016/j.bbadis.2005.06.003, PII S0925443905001031, Mitochondria in Diseases and Therapeutics
-
Facundo HT, Fornazari M, Kowaltowski AJ. Tissue protection mediated by mitochondrial K+ channels. Biochim Biophys Acta 2006;1762:202-12 (Pubitemid 43006026)
-
(2006)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1762
, Issue.2
, pp. 202-212
-
-
Facundo, H.T.F.1
Fornazari, M.2
Kowaltowski, A.J.3
-
42
-
-
42049108814
-
Mechanisms underlying acute protection from cardiac ischemia-reperfusion injury
-
DOI 10.1152/physrev.00024.2007
-
Murphy E, Steenbergen C. Mechanisms underlying acute protection from cardiac ischaemia-reperfusion injury. Physiol Rev 2008;88:581-609 (Pubitemid 351520088)
-
(2008)
Physiological Reviews
, vol.88
, Issue.2
, pp. 581-609
-
-
Murphy, E.1
Steenbergen, C.2
-
43
-
-
0026012567
-
ATP-regulated K+ channels protect the myocardium against ischaemia/reperfusion damage
-
Cole W, McPherson C, Sontag D. ATP-regulated K+ channels protect the myocardium against ischaemia/ reperfusion damage. Circ Res 1991;69:571-81
-
(1991)
Circ. Res.
, vol.69
, pp. 571-581
-
-
Cole, W.1
McPherson, C.2
Sontag, D.3
-
44
-
-
0034782848
-
+ channels in mouse cardiac myocytes
-
DOI 10.1016/S0008-6363(01)00395-9, PII S0008636301003959
-
Knopp A, Thierfelder S, Doepner B, Benndorf K. Mitochondria are the main ATP source for a cytosolic pool controlling the activity of ATP-sensitive K(+) channels in mouse cardiac myocytes. Cardiovasc Res 2001;52(2):236-45 (Pubitemid 33000400)
-
(2001)
Cardiovascular Research
, vol.52
, Issue.2
, pp. 236-245
-
-
Knopp, A.1
Thierfelder, S.2
Doepner, B.3
Benndorf, K.4
-
45
-
-
0034048933
-
Nicorandil, a potent cardioprotective agent, acts by opening mitochondrial ATP-dependent potassium channels
-
DOI 10.1016/S0735-1097(99)00552-5, PII S0735109799005525
-
Sato T, Sasaki N, ORourke B, Marban E. Nicorandil, a potent cardioprotective agent, acts by opening mitochondrial ATP-dependent potassium channels. J Am Coll Cardiol 2000;35(2):514-8 (Pubitemid 30125546)
-
(2000)
Journal of the American College of Cardiology
, vol.35
, Issue.2
, pp. 514-518
-
-
Sato, T.1
Sasaki, N.2
O'Rourke, B.3
Marban, E.4
-
46
-
-
0028182423
-
Effects of the KATP channel opener bimakalim on coronary blood flow monophasic action potential duration and infarct size in dogs
-
Yao Z, Gross GJ. Effects of the KATP channel opener bimakalim on coronary blood flow, monophasic action potential duration, and infarct size in dogs. Circulation 1994;89(4):1769-75
-
(1994)
Circulation
, vol.89
, Issue.4
, pp. 1769-1775
-
-
Yao, Z.1
Gross, G.J.2
-
47
-
-
0028814519
-
Cardioprotective profile of the cardiac-selective ATPsensitive potassium channel opener BMS-180448
-
Grover GJ, McCullough JR, DAlonzo AJ, et al Cardioprotective profile of the cardiac-selective ATPsensitive potassium channel opener BMS-180448. J Cardiovasc Pharmacol 1995;25(1):40-50
-
(1995)
J. Cardiovasc. Pharmacol.
, vol.25
, Issue.1
, pp. 40-50
-
-
Grover, G.J.1
McCullough, J.R.2
D'Alonzo, A.J.3
-
48
-
-
47349093932
-
BK channel openers inhibit ROS production of isolated rat brain mitochondria
-
Kulawiak B, Kudin AP, Szewczyk A, Kunz WS. BK channel openers inhibit ROS production of isolated rat brain mitochondria. Exp Neurol 2008;212:543-7
-
(2008)
Exp. Neurol.
, vol.212
, pp. 543-547
-
-
Kulawiak, B.1
Kudin, A.P.2
Szewczyk, A.3
Kunz, W.S.4
-
49
-
-
0029016089
-
The role of mitochondrial potassium fluxes in controlling the protonmotive force in energized mitochondria
-
Czyz A, Szewczyk A, Nalecz MJ, Wojtczak L. The role of mitochondrial potassium fluxes in controlling the protonmotive force in energized mitochondria, Biochem Biophys Res Commun 1995;210:98-104
-
(1995)
Biochem. Biophys. Res. Commun
, vol.210
, pp. 98-104
-
-
Czyz, A.1
Szewczyk, A.2
Nalecz, M.J.3
Wojtczak, L.4
-
51
-
-
4143097031
-
+ channel activity
-
DOI 10.1073/pnas.0401703101
-
Ardehali H, Chen Z, Ko Y, et al Multiprotein complex containing succinate dehydrogenase confers mitochondrial ATP-sensitive K+ channel activity, Proc Natl Acad Sci USA 2004;101:11880-5 (Pubitemid 39095388)
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, Issue.32
, pp. 11880-11885
-
-
Ardehali, H.1
Chen, Z.2
Ko, Y.3
Mejia-Alvarez, R.4
Marban, E.5
-
52
-
-
1542343927
-
Evidence for mitochondrial K+ channels and their role in cardioprotection
-
ORourke B. Evidence for mitochondrial K+ channels and their role in cardioprotection. Circ Res 2004;94:420-32
-
(2004)
Circ. Res.
, vol.94
, pp. 420-432
-
-
O'Rourke, B.1
-
53
-
-
9644253068
-
Targeting mitochondrial ATP-sensitive potassium channels - A novel approach to neuroprotection
-
DOI 10.1016/j.brainresrev.2004.06.011, PII S0165017304000839
-
Busija DW, Lacza Z, Rajapakse N, et al Targeting mitochondrial ATP-sensitive potassium channels-a novel approach to neuroprotection. Brain Res Brain Res Rev 2004;46:282-94 (Pubitemid 39574329)
-
(2004)
Brain Research Reviews
, vol.46
, Issue.3
, pp. 282-294
-
-
Busija, D.W.1
Lacza, Z.2
Rajapakse, N.3
Shimizu, K.4
Kis, B.5
Bari, F.6
Domoki, F.7
Horiguchi, T.8
-
54
-
-
0034634284
-
Myocardial KATP channels in preconditioning
-
ORourke B. Myocardial KATP channels in preconditioning, Circ Res 2000;87:845-55
-
(2000)
Circ. Res.
, vol.87
, pp. 845-855
-
-
O'Rourke, B.1
-
55
-
-
0035823614
-
Identification and properties of a novel intracellular mitochondrial ATP-sensitive potassium channel in brain
-
Bajgar R, Seetharaman S, Kowaltowski AJ, et al Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain. J Biol Chem 2001;276(36):33369-74
-
(2001)
J. Biol. Chem.
, vol.276
, Issue.36
, pp. 33369-33374
-
-
Bajgar, R.1
Seetharaman, S.2
Kowaltowski, A.J.3
-
56
-
-
1542350297
-
ATP channel opener BMS-191095 induces neuronal preconditioning
-
DOI 10.1097/00001756-200402090-00027
-
Kis B, Nagy K, Snipes JA, et al The mitochondrial K(ATP) channel opener BMS-191095 induces neuronal preconditioning. Neuroreport 2004;15(2):345-9 (Pubitemid 38297363)
-
(2004)
NeuroReport
, vol.15
, Issue.2
, pp. 345-349
-
-
Kis, B.1
Nagy, K.2
Snipes, J.A.3
Rajapakse, N.C.4
Horiguchi, T.5
Grover, G.J.6
Busija, D.W.7
-
57
-
-
0034683225
-
Potassium channel openers prevent β-amyloid toxicity in bovine vascular endothelial cells
-
DOI 10.1016/S0304-3940(00)01293-3, PII S0304394000012933
-
Chi X, Sutton ET, Hellermann G, Price JM. Potassium channel openers prevent beta-amyloid toxicity in bovine vascular endothelial cells. Neurosci Lett 2000;290:9-12 (Pubitemid 30488850)
-
(2000)
Neuroscience Letters
, vol.290
, Issue.1
, pp. 9-12
-
-
Chi, X.1
Sutton, E.T.2
Hellermann, G.3
Price, J.M.4
-
58
-
-
77956220265
-
Mitochondria: The missing link between preconditioning and neuroprotection
-
Correia SC, Santos RX, Perry G, et al Mitochondria: The missing link between preconditioning and neuroprotection. J Alz Disease 2010; 20(Suppl 2):475-85
-
(2010)
J. Alz. Disease
, vol.20
, Issue.2
, pp. 475-485
-
-
Correia, S.C.1
Santos, R.X.2
Perry, G.3
-
59
-
-
65949090732
-
Iptakalim ameliorates MPP+-induced astrocyte mitochondrial dysfunction by increasing mitochondrial complex activity besides opening mitoK ATP channels
-
Zhang S, Ding JH, Zhou F, et al Iptakalim ameliorates MPP+-induced astrocyte mitochondrial dysfunction by increasing mitochondrial complex activity besides opening mitoK(ATP) channels. J Neurosci Res 2009;87(5):1230-9
-
(2009)
J. Neurosci. Res.
, vol.87
, Issue.5
, pp. 1230-1239
-
-
Zhang, S.1
Ding, J.H.2
Zhou, F.3
-
60
-
-
79952052541
-
ATP-dependent potassium channels: A converging target for endogenous anticonvulsant factors
-
Mazarati A. ATP-dependent potassium channels: a converging target for endogenous anticonvulsant factors. Epilepsy Curr 2005;5(4):139-41
-
(2005)
Epilepsy. Curr.
, vol.5
, Issue.4
, pp. 139-141
-
-
Mazarati, A.1
-
61
-
-
0032787545
-
ATP-gated K + channel openers enhance opioid antinociception: Indirect evidence for the release of endogenous opioid peptides
-
Lohmann AB, Welch SP. ATP-gated K (+) channel openers enhance opioid antinociception: indirect evidence for the release of endogenous opioid peptides. Eur J Pharmacol 1999;385:119-27
-
(1999)
Eur. J. Pharmacol.
, vol.385
, pp. 119-127
-
-
Lohmann, A.B.1
Welch, S.P.2
-
62
-
-
4644237028
-
Potassium channels and pain: Present realities and future opportunities
-
DOI 10.1016/j.ejphar.2004.07.026, PII S0014299904007356
-
Ocana M, Cendán CM, Cobos EJ, et al Potassium channels and pain: present realities and future opportunities. Eur J Pharmacol 2004;500:203-19 (Pubitemid 39304009)
-
(2004)
European Journal of Pharmacology
, vol.500
, Issue.SPEC. ISS.
, pp. 203-219
-
-
Ocana, M.1
Cendan, C.M.2
Cobos, E.J.3
Entrena, J.M.4
Baeyens, J.M.5
-
63
-
-
73049095036
-
Sarcolemmal ATP-sensitive K+ channels control
-
Alekseev AE, Reyes S, Yamada S, et al Sarcolemmal ATP-sensitive K+ channels control. Energy expenditure determining body weight. Cell Metab 2010;11:58-69
-
(2010)
Cell Metab.
, vol.11
, pp. 58-69
-
-
Alekseev, A.E.1
Reyes, S.2
Yamada, S.3
-
64
-
-
77954426174
-
Effects of a high fat diet on liver mitochondria: Increased ATP-sensitive K+ channel activity and reactive oxygen species generation
-
Cardoso AR, Cabral-Costa JV, Kowaltowski AJ. Effects of a high fat diet on liver mitochondria: increased ATP-sensitive K+ channel activity and reactive oxygen species generation. J Bioenerg Biomembr 2010;42:245-53
-
(2010)
J. Bioenerg. Biomembr.
, vol.42
, pp. 245-253
-
-
Cardoso, A.R.1
Cabral-Costa, J.V.2
Kowaltowski, A.J.3
-
65
-
-
33744474035
-
ATP channel openers
-
DOI 10.2174/156802606777323647
-
Mannhold R. Structure-activity relationships of K(ATP) channel openers. Curr Top Med Chem 2006;6(10):1031-47 (Pubitemid 43796964)
-
(2006)
Current Topics in Medicinal Chemistry
, vol.6
, Issue.10
, pp. 1031-1047
-
-
Mannhold, R.1
-
66
-
-
33846013945
-
ATP-sensitive potassium channel openers and 2 3-dimethyl-2-butylamine derivatives
-
Wang H, Tang Y, Wang L, et al ATP-sensitive potassium channel openers and 2,3-dimethyl-2-butylamine derivatives. Curr Med Chem 2007;14(2):133-65
-
(2007)
Curr. Med. Chem.
, vol.14
, Issue.2
, pp. 133-165
-
-
Wang, H.1
Tang, Y.2
Wang, L.3
-
67
-
-
0033945753
-
Potassium channel openers as potential therapeutic weapons in ion channel disease
-
DOI 10.1046/j.1523-1755.2000.00923.x
-
Lawson K. Potassium channel openers as potential therapeutic weapons in ion channel disease. Kidney Int 2000;57:838-45 (Pubitemid 30434774)
-
(2000)
Kidney International
, vol.57
, Issue.3
, pp. 838-845
-
-
Lawson, K.1
-
68
-
-
79952044874
-
Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators
-
Solvay Pharmaceuticals GMBH
-
Solvay Pharmaceuticals GMBH. Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators. WO2007125048; 2007
-
(2007)
WO2007125048
-
-
-
69
-
-
79952044874
-
Use of CBX cannabinoid receptor modulators as potassium channel modulators
-
Solvay Pharmaceuticals GMBH
-
Solvay Pharmaceuticals GMBH. Use of CBX cannabinoid receptor modulators as potassium channel modulators. WO2007125049; 2007
-
(2007)
WO2007125049
-
-
-
70
-
-
85047690626
-
The endogenous cennabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis
-
DOI 10.1172/JCI200317725
-
Cota D, Marsicano G, Tschop M, et al The endogenous cannabinoid system affects energy balance via central orexigenic drive and peripheral lipogenesis. J Clin Invest 2003;112(3):423-31 (Pubitemid 38063771)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.3
, pp. 423-431
-
-
Cota, D.1
Marsicano, G.2
Tschop, M.3
Grubler, Y.4
Flachskamm, C.5
Schubert, M.6
Auer, D.7
Yassouridis, A.8
Thone-Reineke, C.9
Ortmann, S.10
Tomassoni, F.11
Cervino, C.12
Nisoli, E.13
Linthorst, A.C.E.14
Pasquali, R.15
Lutz, B.16
Stalla, G.K.17
Pagotto, U.18
-
71
-
-
33644866501
-
Towards selective Kir6.2/SUR1 potassium channel openers medicinal chemistry and therapeutic perspectives
-
Hansen JB. Towards selective Kir6.2/ SUR1 potassium channel openers, medicinal chemistry and therapeutic perspectives. Curr Med Chem 2006;13(4):361-76
-
(2006)
Curr. Med. Chem.
, vol.13
, Issue.4
, pp. 361-376
-
-
Hansen, J.B.1
-
72
-
-
79952044140
-
Use of a combination of diazoxide and metformin for treating obesity or obesity related compounds
-
Cooperatieve Mirzorg U.A. Use of a combination of diazoxide and metformin for treating obesity or obesity related compounds. WO2010093243, 2010
-
(2010)
WO2010093243
-
-
Cooperatieve Mirzorg, U.A.1
-
73
-
-
79952054354
-
Pharmacodynamic hybrids endowed of hypoglicaemic and no-donor activities obtained combining hydroxylated derivatives of glibenclamide and nitrooxy-substituted carboxylic acids
-
Universita di Pisa
-
Universita di Pisa. Pharmacodynamic hybrids endowed of hypoglicaemic and NO-donor activities obtained combining hydroxylated derivatives of glibenclamide and nitrooxy-substituted carboxylic acids. WO2008017925, 2008
-
(2008)
WO2008017925
-
-
-
74
-
-
67749089273
-
NO-glibenclamide derivatives: Prototypes of a new class of nitric oxide-releasing anti-diabetic drugs
-
Calderone V, Rapposelli S, Martelli A, et al NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs. Bioorg Med Chem 2009;17:5426-32
-
(2009)
Bioorg. Med. Chem.
, vol.17
, pp. 5426-5432
-
-
Calderone, V.1
Rapposelli, S.2
Martelli, A.3
-
75
-
-
79952051207
-
Sulfonylurea inhibitors of ATP-sensitive potassium channels
-
Auspex Pharmaceuticals Inc
-
Auspex Pharmaceuticals, Inc. Sulfonylurea inhibitors of ATP-sensitive potassium channels. US20100056546; 2010
-
(2010)
US20100056546
-
-
-
76
-
-
79952062304
-
Sulfonylurea inhibitors of ATP-sensitive potassium channels
-
Auspex Pharmaceuticals Inc
-
Auspex Pharmaceuticals, Inc. Sulfonylurea inhibitors of ATP-sensitive potassium channels. US20100130615; 2010
-
(2010)
US20100130615
-
-
-
77
-
-
79952052067
-
Benzoic acid inhibitors of ATP-sensitive potassium channels
-
Auspex Pharmaceuticals Inc
-
Auspex Pharmaceuticals, Inc. Benzoic acid inhibitors of ATP-sensitive potassium channels. US20100120861; 2010
-
(2010)
US20100120861
-
-
-
78
-
-
79952054941
-
Phenylalanine amide inhibitors of ATP-sensitive potassium channels
-
Auspex Pharmaceuticals Inc
-
Auspex Pharmaceuticals, Inc. Phenylalanine amide inhibitors of ATP-sensitive potassium channels. WO2010060041; 2010
-
(2010)
WO2010060041
-
-
-
79
-
-
79952064180
-
Salts of potassium ATP channel openers and uses thereof
-
Essentialis Inc
-
Essentialis Inc. Salts of potassium ATP channel openers and uses thereof. US20100028429; 2010
-
(2010)
US20100028429
-
-
-
80
-
-
79952064745
-
Pharmaceutical formulations of potassium ATP channel openers and use thereof
-
Essentialis Inc
-
Essentialis Inc. Pharmaceutical formulations of potassium ATP channel openers and use thereof. US20090149451; 2009
-
(2009)
US20090149451
-
-
-
81
-
-
79952058321
-
Intranasal administration of modulators of hypothalamic ATP-sensitive potassium channels
-
Albert Einstein College of Medicine of Yeshiva University Signum Pharmaceutical Inc
-
Albert Einstein College of Medicine of Yeshiva University, Signum Pharmaceutical Inc. Intranasal administration of modulators of hypothalamic ATP-sensitive potassium channels. WO2006088875; 2006
-
(2006)
WO2006088875
-
-
-
82
-
-
79952046062
-
Intranasal administration of modulators of hypothalamic ATP-sensitive potassium channels
-
Herlands L, Pocai A, Rossetti L. Intranasal administration of modulators of hypothalamic ATP-sensitive potassium channels. US20070026079; 2007
-
(2007)
US20070026079
-
-
Herlands, L.1
Pocai, A.2
Rossetti, L.3
-
83
-
-
79952058558
-
Modulation of hypothalamic ATP-sensitive potassium channels
-
Albert Einstein College of Medicine of Yeshiva University
-
Albert Einstein College of Medicine of Yeshiva University. Modulation of hypothalamic ATP-sensitive potassium channels. US20090012067; 2009
-
(2009)
US20090012067
-
-
-
84
-
-
79952066523
-
Nitrogenous N-substituted 4-spiro-heterocyclic 2 2-dimethylchromane derivatives
-
Universitàdi Pisa
-
Universitàdi Pisa. Nitrogenous N-substituted 4-spiro-heterocyclic 2,2-dimethylchromane derivatives. WO2008007210; 2008
-
(2008)
WO2008007210
-
-
-
85
-
-
70350345216
-
Anti-ischaemic properties of a new spiro-cyclic benzopyran activator of the cardiac mitoKATP channel
-
Calderone V, Testai L, Martelli A, et al Anti-ischaemic properties of a new spiro-cyclic benzopyran activator of the cardiac mitoKATP channel. Biochem Pharmacol 2010;79:39-47
-
(2010)
Biochem. Pharmacol.
, vol.79
, pp. 39-47
-
-
Calderone, V.1
Testai, L.2
Martelli, A.3
-
86
-
-
64349100407
-
Enantioselectivity in Cardioprotection induced by S- - - 2 2-Dimethyl-N-4¢-acetamido-benzyl-4-spiromorpholone-chromane
-
Rapposelli S, Calderone V, Cirilli R, et al Enantioselectivity in Cardioprotection induced by (S)-(-)-2,2- Dimethyl-N-(4¢-acetamido-benzyl)- 4- spiromorpholone-chromane. J Med Chem 2009;52(5):1477-80
-
(2009)
J. Med. Chem.
, vol.52
, Issue.5
, pp. 1477-1480
-
-
Rapposelli, S.1
Calderone, V.2
Cirilli, R.3
-
87
-
-
56249144845
-
Spirocyclic benzopyran-based derivatives as new anti-ischaemic activators of mitochondrial ATP-sensitive potassium channel
-
Breschi MC, Calderone V, Digiacomo M, et al Spirocyclic Benzopyran-based derivatives as new anti-ischaemic activators of mitochondrial ATP-sensitive potassium channel. J Med Chem 2008;51(21):6945-54
-
(2008)
J. Med. Chem.
, vol.51
, Issue.21
, pp. 6945-6954
-
-
Breschi, M.C.1
Calderone, V.2
Digiacomo, M.3
-
88
-
-
79952047100
-
Organ protection preservation and recovery
-
Hybernation Therapeutics Ltd
-
Hybernation Therapeutics Ltd. Organ protection, preservation and recovery. US20100256083; 2010
-
(2010)
US20100256083
-
-
-
89
-
-
79952065987
-
Chemical preconditioning as a preventative or treatment for excitotoxic synaptic damage
-
University of Rochester
-
University of Rochester. Chemical preconditioning as a preventative or treatment for excitotoxic synaptic damage. WO2007053514; 2007
-
(2007)
WO2007053514
-
-
-
90
-
-
58549119121
-
Discovery and structure-activity relationships of a novel series of benzopyran-based KATP openers for urge urinary incontinence
-
Zhang X, Qiu Y, Li X, et al Discovery and structure-activity relationships of a novel series of benzopyran-based KATP openers for urge urinary incontinence. Bioorg Med Chem 2009;17:855-66
-
(2009)
Bioorg. Med. Chem.
, vol.17
, pp. 855-866
-
-
Zhang, X.1
Qiu, Y.2
Li, X.3
-
91
-
-
79952065986
-
Novel tricyclic dihydropyrazines as potassium channel openers
-
Zhang X, Sui Z. Novel tricyclic dihydropyrazines as potassium channel openers. US20070191382; 2007
-
(2007)
US20070191382
-
-
Zhang, X.1
Sui, Z.2
-
92
-
-
79952055568
-
Novel tricyclic dihydropyrazines as potassium channel openers
-
Janssen Pharmaceutica NV
-
Janssen Pharmaceutica NV. Novel tricyclic dihydropyrazines as potassium channel openers. WO2007095424; 2007
-
(2007)
WO2007095424
-
-
-
93
-
-
79952064994
-
Novel pyridine derivatives as potassium ion channel openers
-
Janssen Pharmaceutica NV
-
Janssen Pharmaceutica NV. Novel pyridine derivatives as potassium ion channel openers. WO2006091800; 2006
-
(2006)
WO2006091800
-
-
-
94
-
-
79952060065
-
Novel coumarin derivatives as ion channel openers
-
Janssen Pharmaceutica NV
-
Janssen Pharmaceutica NV. Novel coumarin derivatives as ion channel openers. WO2006078833; 2006
-
(2006)
WO2006078833
-
-
-
95
-
-
79952044399
-
Novel benzopyran derivatives as potassium channel openers
-
Janssen Pharmaceutica NV
-
Janssen Pharmaceutica NV. Novel benzopyran derivatives as potassium channel openers. WO2007027780; 2007
-
(2007)
WO2007027780
-
-
-
96
-
-
79952046803
-
Novel quinoline derivatives as potassium ion channel openers
-
Janssen Pharmaceutica NV
-
Janssen Pharmaceutica NV. Novel quinoline derivatives as potassium ion channel openers. WO2006091769; 2006
-
(2006)
WO2006091769
-
-
-
97
-
-
79952064046
-
3 4-diamino-3-cyclobutene-1 2-dione derivatives as potassium channel openers
-
Lanter JC, Sui Z. 3,4-diamino-3- cyclobutene-1,2-dione derivatives as potassium channel openers. US20090312412; 2009
-
(2009)
US20090312412
-
-
Lanter, J.C.1
Sui, Z.2
-
98
-
-
79952051933
-
Novel pyrazolylquinazolinones as potassium channel openers
-
Zhang X, Sui Z. Novel pyrazolylquinazolinones as potassium channel openers. US20070197566; 2007
-
(2007)
US20070197566
-
-
Zhang, X.1
Sui, Z.2
-
99
-
-
79952054237
-
Application of chromane HEF-05 in relaxation of vascular smooth muscles
-
Shenyang Pharmaceutical University
-
Shenyang Pharmaceutical University. Application of chromane HEF-05 in relaxation of vascular smooth muscles. CN101829081; 2010
-
(2010)
CN101829081
-
-
-
100
-
-
79952046663
-
New medical application of chromane compound HEF-05
-
Shenyang Pharmaceutical University
-
Shenyang Pharmaceutical University. New medical application of chromane compound HEF-05. CN101618033; 2010
-
(2010)
CN101618033
-
-
-
101
-
-
79952060657
-
Treatment of migraine and headaches
-
Region Hovedstaden Glostrup Hospital
-
Region Hovedstaden Glostrup Hospital, Olesen IJ, Olesen J. Treatment of migraine and headaches. WO2007009462; 2007
-
(2007)
WO2007009462
-
-
Olesen, I.J.1
Olesen, J.2
|