Altered Ca2+ handling by ryanodine receptor and Na +-Ca2+ exchange in the heart from ovariectomized rats: Role of protein kinase A

American Journal of Physiology - Cell Physiology

Volumn 292, Issue 5, 2007, Pages

  Kravtsov, Gennadi M ^a   Kam, Kenneth W L ^a   Liu, Jing ^a   Wu, Song ^a   Wong, Tak Ming ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Ovariectomy

Indexed keywords

ADENOSINE TRIPHOSPHATASE (CALCIUM); CAFFEINE; CALCIUM ION; CYCLIC AMP DEPENDENT PROTEIN KINASE; ESTROGEN; RYANODINE RECEPTOR; PROTEIN KINASE INHIBITOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SODIUM CALCIUM EXCHANGE PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOSOL; ELECTROSTIMULATION; ESTROGEN THERAPY; FEMALE; HEART; HEART MUSCLE CELL; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SODIUM CALCIUM EXCHANGE; SPRAGUE DAWLEY RAT; ANIMAL; CALCIUM SIGNALING; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; HEART CONTRACTION; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE; HOMEOSTASIS; METABOLISM; TIME; UPREGULATION;

RATTUS;

ANIMALS; CAFFEINE; CALCIUM SIGNALING; CYCLIC AMP-DEPENDENT PROTEIN KINASES; ELECTRIC STIMULATION; ESTROGENS; FEMALE; HEART VENTRICLES; HOMEOSTASIS; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; OVARIECTOMY; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SODIUM-CALCIUM EXCHANGER; TIME FACTORS; UP-REGULATION; VENTRICULAR FUNCTION, LEFT;

EID: 34250673589     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00368.2006     Document Type: Article

References (38)

1. Bassani JW, Bassani RA, Bers DM. Relaxation in rabbit and rat cardiac cells: species-dependent differences in cellular mechanisms. J Physiol 476: 279-293, 1994.
2. Bers DM. Cardiac excitation-contraction coupling. Nature 415: 198-205, 2002.
3. Bowling N, Bloomquist WE, Cohen ML, Bryant HU, Cole HW, Magee DE, Rowley ER, Vlahos CJ. Effects of prolonged ethinyl estradiol treatment on calcium channel binding and in vivo calcium-mediated hemodynamic responses in ovariectomized rats. J Pharmacol Exp Ther 281: 218-225, 1997.
4. Cheng H, Lederer WJ, Cannell MB. Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262: 740-744, 1993.
5. i in female rat cardiac myocytes. Clin Exp Pharmacol Physiol 30: 489-494, 2003.
6. Díaz ME, Graham HK, O'Neill SC, Trafford AW, Eisner DA. The control of sarcoplasmic reticulum Ca content in cardiac muscle. Cell Calcium 38: 391-396, 2005.
7. Eisner DA, Choi HS, Diaz ME, O'Neill SC, Trafford AW. Integrative analysis of calcium cycling in cardiac muscle. Circ Res 87: 1087-1094, 2000.
8. Fatkin D, Graham RM. Molecular mechanism of inherited cardiomyopathies. Physiol Rev 82: 945-980, 2002.
9. Ginsburg KS, Bers DM. Isoproterenol does not enhance Ca-dependent Na/Ca exchange current in intact rabbit ventricular myocytes. J Mol Cell Cardiol 39: 872-981, 2005.
10. Glass DB, Cheng HC, Mueller LM, Reed J, Walsh DA. Primary structural determinats essential for potent inhibition of cAMP-dependent proteine kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein. J Biol Chem 264: 8802-8810, 1989.
11. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985.
12. Ho JC, Wu S, Kam KW, Sham JS, Wong TM. Effects of pharmacological preconditioning with U50488H on calcium homeostasis in rat ventricular myocytes subjected to metabolic inhibition and anoxia. Br J Pharmacol 137: 739-748, 2002.
13. 2+ uptake and thapsigargin sensitivity in permeabilized rabbit and rat ventricular myocytes. Circ Res 73: 820-828, 1993.
14. Johnson BD, Zheng W, Korach KS, Scheuer T, Catterall WA, Rubanyi GM. Increased expression of the cardiac L-type calcium channel in estrogen receptor-deficient mice. J Gen Physiol 110: 135-140, 1997.
15. 2+ channels in the heart of ovariectomized rat. Br J Pharmacol 144: 972-981, 2005.
16. Kase H, Iwahashi K, Nakanishi S, Matsuda Y, Yamada K, Takahashi M, Murakata C, Sato A, Kaneko M. K-252 compounds, novel and potent inhibitors of protein kinase C and cyclic nucleotide-dependent protein kinases. Biochem Biophys Res Commun 142: 436-440, 1987.
17. Kolodgie FD, Farb A, Litovsky SH, Narula J, Jeffers LA, Lee SJ, Virmani R. Myocardial protection of contractile function after global ischemia by physiologic estrogen replacement in the ovariectomized rat. J Mol Cell Cardiol 29: 2403-2414, 1997.
18. Lehnart SE, Wehrens XHT, Kushnir A, Marks A. Cardiac ryanodine receptor function and regulation in heart disease. Ann NY Acad Sci 1015: 144-159, 2004.
19. 2+-ATPase. Circ Res 83: 889-897, 1998.
20. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ. Protein measurement with folin phenol reagent. J Biol Chem 193: 265-275, 1951.
21. Marx SO, Reiken S, Hisamatsu Y, Jayaraman T, Burkhoff D, Rosemblit N, Marks AR. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor); defective regulation in failing hearts. Cell 101: 365-376, 2000.
22. Patterson E, Ma L, Szabo B, Robinson CP, Thadani U. Ovariectomy and estrogen-induced alterations in myocardial contractility in female rabbits: role of the L-type calcium channel. J Pharmacol Exp Ther 284: 586-591, 1998.
23. Pei JM, Kravtsov GM, Wu S, Das R, Fung ML, Wong TM. Calcium homeostasis in rat cardiomyocytes during chronic hypoxia: a time course study. Am J Physiol Cell Physiol 285: C1420-C1428, 2003.
24. Ren J, Hintz KK, Roughead ZK, Duan J, Colligan PB, Ren BH, Lee KJ, Zeng H. Impact of estrogen replacement on ventricular myocyte contractile function and protein kinase B/Akt activation. Am J Physiol Heart Circ Physiol 284: H1800-H1807, 2003.
25. 2+ exchangers by PKA. Ann NY Acad Sci 976: 209-213, 2002.
26. i-increasing agents cyclopiazonic acid and thapsigargin. J Biol Chem 269: 8786-8791, 1994.
27. Schaible TF, Malhotra A, Ciambrone G, Scheuer J. The effects of gonadectomy on left ventricular function and cardiac contractile proteins in male and female rats. Circ Res 54: 38-49, 1984.
28. Scheuer J, Malhotra A, Schailbe TF, Capasso J. Effects of gonadectomy and hormonal replacement on rat hearts. Circ Res 61: 12-19, 1987.
29. Schulze DH, Muqhal M, Lederer WJ, Ruknudin AM. Sodium/calcium exchanger (NCX1) macromolecular complex. J Biol Chem 278: 28849-28855, 2003.
30. 2+ exchanger in mammalian cardiac myocytes. J Physiol 488: 623-631, 1995.
31. 2+ exchange. Molecular and pharmacological aspects. Circ Res 88: 864-876, 2001.
32. Solaro RJ, Rarick HM. Troponin and tropomyosin: proteins that switch on and tune in the activity of cardiac myofilaments. Circ Res 83: 471-480, 1998.
33. Stern MD. Theory of excitation-contraction coupling in cardiac muscle. Biophys J 63: 497-517, 1992.
34. 2+ exchanger. J Physiol 512: 651-667, 1998.
35. Terracciano CMN, Tweedie D, Mcleod KT. The effects of changes to action potential duration on the calcium content of the sarcoplasmic reticulum in isolated guinea-pig ventricular myocytes. Pflügers Arch 443: 542-544, 1997.
36. 2+ turnover in skinned muscle fibers. Biophys J 74: 1640-1653, 1998.
37. Wattanapermpool J, Reiser PJ. Differential effects of ovariectomy on calcium activation of cardiac and soleus myofilaments. Am J Physiol Heart Circ Physiol 277: H467-H473, 1999.
38. Wu S, Li HY, Wong TM. Cardioprotection of preconditioning by metabolic inhibition in the rat ventricular myocyte. Involvement of κ-opioid receptor. Circ Res 84: 1388-1395, 1999.