Cardiac sodium-calcium exchanger is regulated by allosteric calcium and exchanger inhibitory peptide at distinct sites

Circulation Research

Volumn 96, Issue 1, 2005, Pages 91-99

  Maack, Christoph ^a   Ganesan, Anand ^a   Sidor, Agnieszka ^a   O'Rourke, Brian ^a,b  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Institute of Molecular Cardiobiology   (United States)

Author keywords

Adenovirus; Cardiac myocytes; Mutation

Indexed keywords

CALCIUM ION; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE; PROTEIN; PROTEIN EXCHANGER INHIBITORY PEPTIDE; SODIUM CALCIUM EXCHANGE PROTEIN; SODIUM ION; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; DELETION MUTANT; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HOMEOSTASIS; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SARCOLEMMA; SODIUM CALCIUM EXCHANGE; SODIUM CELL LEVEL; VOLTAGE CLAMP;

ACTION POTENTIALS; ADENOCARCINOMA; ADENOVIRIDAE; ALLOSTERIC REGULATION; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CALCIUM; CELL LINE; CELL LINE, TUMOR; GENETIC VECTORS; GUINEA PIGS; HUMANS; KIDNEY; LUNG NEOPLASMS; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MYOCYTES, CARDIAC; PATCH-CLAMP TECHNIQUES; PEPTIDES; PHOSPHATIDYLINOSITOL 4,5-DIPHOSPHATE; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; SARCOLEMMA; SEQUENCE DELETION; SODIUM; SODIUM-CALCIUM EXCHANGER;

EID: 11844284767     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000151334.48676.68     Document Type: Article

References (38)

1. Kimura J, Miyamae S, Noma A. Identification of sodium-calcium exchange current in single ventricular cells of guinea-pig. J Physiol. 1987;384:199-222.
2. 2+ exchange in inside-out patches excised from guinea-pig ventricular myocytes. J Physiol 2000;523:339-351.
3. Bers DM. Calcium fluxes involved in control of cardiac myocyte contraction. Circ Res. 2000;87:275-281.
4. + concentration is elevated in heart failure but Na/K pump function is unchanged. Circulation. 2002;105:2543-2548.
5. Armoundas AA, Hobai IA, Tomaselli GF, Winslow RL, O'Rourke B. Role of sodium-calcium exchanger in modulating the action potential of ventricular myocytes from normal and failing hearts. Circ Res. 2003;93:46-53.
6. +]i and contractility in nonfailing and failing human myocardium. Circulation. 2002;106:447-453.
7. Weber CR, Piacentino V, 3rd, Houser SR, Bers DM. Dynamic regulation of sodium/calcium exchange function in human heart failure. Circulation. 2003;108:2224-2229.
8. 2+] during the cardiac action potential. Circ Res. 2002;90:182-189.
9. 2+ transient of failing human ventricular myocytes. Circ Res. 1999;84:435-444.
10. Hobai IA, Maack C, O'Rourke B. Partial inhibition of sodium/calcium exchange restores cellular calcium handling in canine heart failure. Circ Res. 2004;95:292-299.
11. Philipson KD, Nicoll DA. Sodium-calcium exchange: a molecular perspective. Annu Rev Physiol. 2000;62:111-133.
12. 2+ exchange: molecular and pharmacological aspects. Circ Res. 2001;88:864-876.
13. 2+ exchanger. J Biol Chem. 1991;266:1014-1020.
14. 2+ exchanger by the endogenous XIP region. J Gen Physiol. 1997;109:273-286.
15. He Z, Feng S, Tong Q, Hilgemann DW, Philipson KD. Interaction of PIP(2) with the XIP region of the cardiac Na/Ca exchanger. Am J Physiol Cell Physiol. 2000;278:C661-6.
16. 2+ exchange and KATP potassium channels by PIP2. Science. 1996;273:956-959.
17. Kleiboeker SB, Milanick MA, Hale CC. Interactions of the exchange inhibitory peptide with Na-Ca exchange in bovine cardiac sarcolemmal vesicles and ferret red cells. J Biol Chem. 1992;267:17836-17841.
18. 2+ exchanger. Proc Natl Acad Sci U S A. 1993;90:3870-3874.
19. 2+ exchanger. J Biol Chem. 1994;269:22847-22852.
20. 2+-binding domain. J Gen Physiol. 1995;105:403-420.
21. 2+ exchange assessed in transgenic mouse hearts. Am J Physiol. 1999;277:H2212-21.
22. Weber CR, Ginsburg KS, Philipson KD, Shannon TR, Bers DM. Allosteric regulation of Na/Ca exchange current by cytosolic Ca in intact cardiac myocytes. J Gen Physiol. 2001;117:119-131.
23. Patton C, Thompson S, Epel D. Some precaustions in using chelators to buffer metals in biological solutions. Cell Calcium. 2004;35:427-431.
24. O'Rourke B, Kass DA, Tomaselli GF, Kaab S, Tunin R, Marban E. Mechanisms of altered excitation-contraction coupling in canine tachycardia-induced heart failure, I: experimental studies. Circ Res. 1999;84:562-570.
25. 2+ indicators with greatly improved fluorescence properties. J Biol Chem. 1985;260:3440-3450.
26. Bassani JW, Bassani RA, Bers DM. Calibration of indo-1 and resting intracellular [Ca]i in intact rabbit cardiac myocytes. Biophys J. 1995;68:1453-1460.
27. 2+ exchange in giant excised sarcolemmal membrane patches. Nature. 1990;344:242-245.
28. Hale CC, Bliler S, Quinn TP, Peletskaya EN. Localization of an exchange inhibitory peptide (XIP) binding site on the cardiac sodium-calcium exchanger. Biochem Biophys Res Commun. 1997;236:113-117.
29. Xu W, Denison H, Hale CC, Gatto C, Milanick MA. Identification of critical positive charges in XIP, the Na/Ca exchange inhibitory peptide. Arch Biochem Biophys. 1997;341:273-279.
30. Chin TK, Spitzer KW, Philipson KD, Bridge JH. The effect of exchanger inhibitory peptide (XIP) on sodium-calcium exchange current in guinea pig ventricular cells. Circ Res. 1993;72:497-503.
31. Bossuyt J, Taylor BE, James-Kracke M, Hale CC. The cardiac sodium-calcium exchanger associates with caveolin-3. Ann NY Acad Sci. 2002;976:197-204.
32. Cha SH, Jung NH, Kim BR, Kim HW, Kwak JO. Evidence for cyclooxygenase-1 association with caveolin-1 and -2 in cultured human embryonic kidney (HEK 293) cells. IUBMB Life. 2004;56:221-227.
33. 2+ exchanger. Biochim Biophys Acta. 1994;1196:97-99.
34. 2+ exchanger. Science. 1990;250:562-565.
35. Reeves JP, Condrescu M. Allosteric activation of sodium-calcium exchange activity by calcium: persistence at low calcium concentrations. J Gen Physiol. 2003;122:621-639.
36. 2+ J Gen Physiol. 1997;109:361-369.
37. Hilgemann DW, Matsuoka S, Nagel GA, Collins A. Steady-state and dynamic properties of cardiac sodium-calcium exchange. Sodium-dependent inactivation. J Gen Physiol. 1992;100:905-932.
38. 2+ exchanger. Mol Cell Biochem. 1996;160-161:27-32.