Decreased hepatic breast cancer resistance protein expression and function in multidrug resistance-associated protein 2-deficient (TR-) rats

Drug Metabolism and Disposition

Volumn 39, Issue 3, 2011, Pages 441-447

  Yue, Wei ^a   Lee, Jin Kyung ^a   Abe, Koji ^a   Sugiyama, Yuichi ^a   Brouwer, Kim L R ^a  

^a University of North Carolina   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BREAST CANCER RESISTANCE PROTEIN; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 2; NITROFURANTOIN; PITAVASTATIN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG BILE LEVEL; DRUG DISPOSITION; GENE EXPRESSION; LIVER CELL; LIVER PERFUSION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WILD TYPE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTI-BACTERIAL AGENTS; ATP-BINDING CASSETTE TRANSPORTERS; BILE; BILIARY TRACT; BIOLOGICAL TRANSPORT; CELLS, CULTURED; GENE EXPRESSION REGULATION; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; HYPERBILIRUBINEMIA; LIVER; MALE; METABOLIC CLEARANCE RATE; NITROFURANTOIN; QUINOLINES; RATS; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING;

RATTUS; RATTUS NORVEGICUS;

EID: 79951879438     PISSN: 00909556     EISSN: 1521009X     Source Type: Journal    
DOI: 10.1124/dmd.110.035188     Document Type: Article

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