Mrp2-deficiency in the rat impairs biliary and intestinal excretion and influences metabolism and dispostion of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)

Carcinogenesis

Volumn 22, Issue 5, 2001, Pages 805-811

  Dietrich, Christoph G ^b   De Waart, D Rudi ^a   Ottenhoff, Roel ^a   Bootsma, Albert H ^a   Van Gennip, Albert H ^a   Oude Elferink, Ronald P J ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; ALCOHOL; BUTHIONINE SULFOXIMINE; CARCINOGEN; GLUCURONIDE; GLUTATHIONE; HETEROCYCLIC AMINE; MULTIDRUG RESISTANCE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE; BILIARY EXCRETION; CONTROLLED STUDY; FEMALE; FOOD; INTESTINE; INTESTINE MUCOSA; LIVER LEVEL; METABOLISM; METABOLITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; RAT; RAT STRAIN; SECRETION; SPECIES; TIME; TISSUE LEVEL;

ANIMALS; BILIARY TRACT; CARCINOGENS; FEMALE; IMIDAZOLES; INJECTIONS, INTRAVENOUS; INTESTINES; MITOCHONDRIAL PROTEINS; RATS; RATS, WISTAR; RIBOSOMAL PROTEINS; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 0035033560     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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