Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability

Oncogene

Volumn 30, Issue 7, 2011, Pages 790-805

  Latonen, L ^a,c   Moore, H M ^a   Bai, B ^b   Jaamaa S ^a   Laiho, M ^a,b  

^a UNIVERSITY OF HELSINKI   (Finland)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c UNIVERSITY OF TAMPERE   (Finland)

Author keywords

aggresome; nuclear export; polyadenylated RNA; proteasome; proteasome inhibitor; ubiquitin

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 1; CYCLIN DEPENDENT KINASE; CYCLINE; EXPORTIN 1; POLYADENYLATED RNA; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN P53; RETINOBLASTOMA PROTEIN; RIBOSOME RNA; UBIQUITIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; NUCLEOLUS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN STRUCTURE; PROTEIN TARGETING; PROTEIN TRANSPORT; RNA SYNTHESIS;

ACETYLCYSTEINE; CELL CYCLE PROTEINS; CELL LINE; CELL NUCLEOLUS; CYCLIN-DEPENDENT KINASES; CYCLINS; CYSTEINE PROTEINASE INHIBITORS; DNA-BINDING PROTEINS; HUMANS; LEUCINE; LEUPEPTINS; NUCLEAR PROTEINS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN;

ATAXIA TELANGIECTASIA; MAMMALIA;

EID: 79951814094     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2010.469     Document Type: Article

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