Lipopolysaccharide down-regulates carbolesterases 1 and 2 and reduces hydrolysis activity in vitro and in vivo via p38MAPK-NF-κB pathway

Toxicology Letters

Volumn 201, Issue 3, 2011, Pages 213-220

  Mao, Zhao ^a,b   Li, Yang ^a   Peng, Yan ^a   Luan, Xiaofei ^a   Gui, Haiyan ^a   Feng, Xuemin ^a   Hu, Gang ^a   Shen, Jianping ^a   Yan, Bingfang ^c   Yang, Jian ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b JINLING HOSPITAL   (China)

^c UNIVERSITY OF RHODE ISLAND   (United States)

Author keywords

Carboxylesterases 1; Carboxylesterases 2; Lipopolysaccharide; NF B; P38MAPK

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CARBOXYLESTERASE; CLOPIDOGREL; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IRINOTECAN; LIPOPOLYSACCHARIDE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PYRROLIDINE DITHIOCARBAMATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; HUMAN; HUMAN CELL; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; BLOTTING, WESTERN; CAMPTOTHECIN; CARBOXYLIC ESTER HYDROLASES; CELL SURVIVAL; CELLS, CULTURED; DOWN-REGULATION; ENZYME INHIBITORS; GENES, REPORTER; HUMANS; HYDROLYSIS; LIPOPOLYSACCHARIDES; MALE; MICE; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLATELET AGGREGATION INHIBITORS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUBCELLULAR FRACTIONS; TICLOPIDINE; TRANSFECTION;

EID: 79951774151     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxlet.2011.01.002     Document Type: Article

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