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Volumn 14, Issue 3-4, 2008, Pages 160-166

Involvement of the p38 MAPK-NF-κB signal transduction pathway and COX-2 in the pathobiology of meniscus degeneration in humans

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; DIMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; P65 PROTEIN; PROTEIN P50; UNCLASSIFIED DRUG;

EID: 41649114143     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/2007-00138.Papachristou     Document Type: Article
Times cited : (35)

References (35)
  • 2
    • 0025361721 scopus 로고
    • The ultrastructure and biochemistry of meniscal cartilage
    • McDevitt CA, Webber RJ. (1990) The ultrastructure and biochemistry of meniscal cartilage. Clin. Orthop. Rel. Res. 252:8-18.
    • (1990) Clin. Orthop. Rel. Res , vol.252 , pp. 8-18
    • McDevitt, C.A.1    Webber, R.J.2
  • 3
    • 0020571475 scopus 로고
    • Ultrastructure of normal and torn menisci of the human knee joint
    • Ghadially F, Lalonde J, Wedge J. (1983) Ultrastructure of normal and torn menisci of the human knee joint. J. Anat. 136:773-91.
    • (1983) J. Anat , vol.136 , pp. 773-791
    • Ghadially, F.1    Lalonde, J.2    Wedge, J.3
  • 4
    • 0040419659 scopus 로고
    • Factors influencing the progression of osteoarthritis
    • Ewing JW ed, Raven Press, New York, p
    • Radin EL. (1990) Factors influencing the progression of osteoarthritis. In: Articular Cartilage and Knee Joint Function. Ewing JW (ed.). Raven Press, New York, p. 301-9.
    • (1990) Articular Cartilage and Knee Joint Function , pp. 301-309
    • Radin, E.L.1
  • 5
    • 0035126392 scopus 로고    scopus 로고
    • Early changes in lapine menisci during osteoarthritis development. Part II: Molecular alterations
    • Hellio Le Gravetand M, Vigon E, Otterness IG, Hart DA. (2001) Early changes in lapine menisci during osteoarthritis development. Part II: molecular alterations. Osteoarthritis Cart. 9:65-72.
    • (2001) Osteoarthritis Cart , vol.9 , pp. 65-72
    • Hellio Le Gravetand, M.1    Vigon, E.2    Otterness, I.G.3    Hart, D.A.4
  • 8
    • 4344688814 scopus 로고    scopus 로고
    • Signaling transduction: Target in osteoarthritis
    • Berenbaum F. (2004) Signaling transduction: target in osteoarthritis. Curr. Opin. Rheumatol. 16:616-22.
    • (2004) Curr. Opin. Rheumatol , vol.16 , pp. 616-622
    • Berenbaum, F.1
  • 10
    • 0142026209 scopus 로고    scopus 로고
    • p38 MAP kinases: Key signaling molecules as therapeutic targets for inflammatory disease
    • Kumar S, Bohem J, Lee JC. (2003) p38 MAP kinases: key signaling molecules as therapeutic targets for inflammatory disease. Nat. Rev. Drug Discov. 2:717-26.
    • (2003) Nat. Rev. Drug Discov , vol.2 , pp. 717-726
    • Kumar, S.1    Bohem, J.2    Lee, J.C.3
  • 11
    • 0037032817 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase pathways mediated by ERK, JNK and p38 protein kinases
    • Johnson GL, Lapadat R. (2002) Mitogen-activated protein kinase pathways mediated by ERK, JNK and p38 protein kinases. Science 289:1911-2.
    • (2002) Science , vol.289 , pp. 1911-1912
    • Johnson, G.L.1    Lapadat, R.2
  • 12
    • 0034213138 scopus 로고    scopus 로고
    • p38 MAP kinases: Beyond the stress response
    • Nebreda AR, Porras A. (2000) p38 MAP kinases: beyond the stress response. Trends Biochem. Sci. 25:257-60.
    • (2000) Trends Biochem. Sci , vol.25 , pp. 257-260
    • Nebreda, A.R.1    Porras, A.2
  • 14
    • 33745342580 scopus 로고    scopus 로고
    • NF-κB pathway: A good signaling paradigm for therapeutic target
    • Tergaonkar V. (2006) NF-κB pathway: a good signaling paradigm for therapeutic target. Int. J. Biochem. Cell Biol. 38:1647-53.
    • (2006) Int. J. Biochem. Cell Biol , vol.38 , pp. 1647-1653
    • Tergaonkar, V.1
  • 15
    • 0027232067 scopus 로고
    • NF-κB and Rel: Participants in a multiform transcriptional regulatory system
    • Grilli M, Chiu JJ, Lenardo MJ. (1993) NF-κB and Rel: participants in a multiform transcriptional regulatory system. Int. Rev. Cytol. 143:1-62.
    • (1993) Int. Rev. Cytol , vol.143 , pp. 1-62
    • Grilli, M.1    Chiu, J.J.2    Lenardo, M.J.3
  • 16
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Hayden MS, Ghosh S. (2004) Signaling to NF-κB. Genes Dev. 18:2195-224.
    • (2004) Genes Dev , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 17
    • 0030615201 scopus 로고    scopus 로고
    • Nuclear factor-kappaB: A pivotal transcription factor in chronic inflammatory diseases
    • Barnes PJ, Karin M. (1997) Nuclear factor-kappaB: a pivotal transcription factor in chronic inflammatory diseases. N. Engl. J. Med. 336:1066-71.
    • (1997) N. Engl. J. Med , vol.336 , pp. 1066-1071
    • Barnes, P.J.1    Karin, M.2
  • 18
    • 0033791318 scopus 로고    scopus 로고
    • Cyclooxygenases: Structural, cellular, and molecular biology
    • Smith WL, DeWitt DL, Garavito RM. (2000) Cyclooxygenases: structural, cellular, and molecular biology. Annu. Rev. Biochem. 69:145-82.
    • (2000) Annu. Rev. Biochem , vol.69 , pp. 145-182
    • Smith, W.L.1    DeWitt, D.L.2    Garavito, R.M.3
  • 19
    • 34247505895 scopus 로고    scopus 로고
    • Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation
    • Kang Y-L, Mbonye UR, DeLong CL, Wada M, Smith WL. (2007) Regulation of intracellular cyclooxygenase levels by gene transcription and protein degradation. Prog. Lipids Res. 46:108-25.
    • (2007) Prog. Lipids Res , vol.46 , pp. 108-125
    • Kang, Y.-L.1    Mbonye, U.R.2    DeLong, C.L.3    Wada, M.4    Smith, W.L.5
  • 21
    • 0025304539 scopus 로고
    • Rheumatoid arthritis: Pathophysiology and implications for therapy
    • Harris E. (1990) Rheumatoid arthritis: pathophysiology and implications for therapy. N. Engl. J. Med. 322:1277.
    • (1990) N. Engl. J. Med , vol.322 , pp. 1277
    • Harris, E.1
  • 25
    • 0016769319 scopus 로고
    • The pathology of degenerated meniscus lesion
    • Noble J, Hamblen DL. (1975) The pathology of degenerated meniscus lesion. J. Bone Joint Surg. Br. 57:180-6.
    • (1975) J. Bone Joint Surg. Br , vol.57 , pp. 180-186
    • Noble, J.1    Hamblen, D.L.2
  • 26
    • 33646477967 scopus 로고    scopus 로고
    • Molecular mechanisms of cartilage destruction: Mechanics, inflammatory mediators, and aging collide
    • Loeser RF. (2006) Molecular mechanisms of cartilage destruction: mechanics, inflammatory mediators, and aging collide. Arthritis Rheum. 54:1357-60.
    • (2006) Arthritis Rheum , vol.54 , pp. 1357-1360
    • Loeser, R.F.1
  • 27
    • 0033197876 scopus 로고    scopus 로고
    • Gene expression in menisci from knees of skeletally mature female rabbits
    • Hellio Le Gravetand M, Reno C, Hart DA. (1999) Gene expression in menisci from knees of skeletally mature female rabbits. J. Orthop. Res. 17:738-44.
    • (1999) J. Orthop. Res , vol.17 , pp. 738-744
    • Hellio Le Gravetand, M.1    Reno, C.2    Hart, D.A.3
  • 28
    • 34248580620 scopus 로고    scopus 로고
    • Role of apoptotic and matrix-degrading genes in articular cartilage and meniscus of mature and aged rabbits during development of osteoarthritis
    • Pennock AT, Robertson CM, Emmerson BC, Harwood FL, Amiel D. (2007) Role of apoptotic and matrix-degrading genes in articular cartilage and meniscus of mature and aged rabbits during development of osteoarthritis. Arthritis Rheum. 56:1529-36.
    • (2007) Arthritis Rheum , vol.56 , pp. 1529-1536
    • Pennock, A.T.1    Robertson, C.M.2    Emmerson, B.C.3    Harwood, F.L.4    Amiel, D.5
  • 29
    • 0031955304 scopus 로고    scopus 로고
    • The effect of ageing and osteoarthritis on the mature and senescent cross-links of collagen in human meniscus
    • Takahashi M, Suzuki M, Kushida K, Hoshino H, Innue T. (1998) The effect of ageing and osteoarthritis on the mature and senescent cross-links of collagen in human meniscus. Arthroscopy. 14:366-72.
    • (1998) Arthroscopy , vol.14 , pp. 366-372
    • Takahashi, M.1    Suzuki, M.2    Kushida, K.3    Hoshino, H.4    Innue, T.5
  • 30
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signaling cascades
    • Chang L, Karin M. (2001) Mammalian MAP kinase signaling cascades. Nature. 410:37-40.
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 31
    • 34247179473 scopus 로고    scopus 로고
    • A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis
    • Cuardo A, Lafarga V, Cheung PCF, Donaldo I, Llanos S, Cohen P, Nebreda AR. (2007) A new p38 MAP kinase-regulated transcriptional coactivator that stimulates p53-dependent apoptosis. EMBO J. 26:2115-26.
    • (2007) EMBO J , vol.26 , pp. 2115-2126
    • Cuardo, A.1    Lafarga, V.2    Cheung, P.C.F.3    Donaldo, I.4    Llanos, S.5    Cohen, P.6    Nebreda, A.R.7
  • 32
    • 0034746919 scopus 로고    scopus 로고
    • NF-?B: A key role in inflammatory disease
    • Tak PP, Firestein GS. (2001) NF-?B: a key role in inflammatory disease. J. Clin. Invest. 107:7-11.
    • (2001) J. Clin. Invest , vol.107 , pp. 7-11
    • Tak, P.P.1    Firestein, G.S.2
  • 35


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.