Lipoteichoic acid enhances IL-6 production in human synovial fibroblasts via TLR2 receptor, PKCδ and c-Src dependent pathways

Biochemical Pharmacology

Volumn 79, Issue 11, 2010, Pages 1648-1657

  Tang, Chih Hsin ^a   Hsu, Chin Jung ^a,b   Yang, Wei Hung ^a,c   Fong, Yi Chin ^a,b  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY BEIGANG HOSPITAL   (Taiwan)

Author keywords

C Src; IL 6; LTA; PKC; RA

Indexed keywords

INTERLEUKIN 6; LIPOTEICHOIC ACID; PROTEIN C JUN; PROTEIN KINASE C DELTA; PROTEIN KINASE P60; SMALL INTERFERING RNA; SYNAPTOTAGMIN I; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG ACTIVITY; ENZYME ACTIVITY; FIBROBLAST; GENE ACTIVATION; GENE EXPRESSION; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN SYNTHESIS; RHEUMATOID ARTHRITIS; SIGNAL TRANSDUCTION; SYNOVIUM; UPREGULATION;

ARTHRITIS, RHEUMATOID; CELLS, CULTURED; FIBROBLASTS; HUMANS; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; NF-KAPPA B; PROTEIN KINASE C-DELTA; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; SIGNAL TRANSDUCTION; SYNOVIAL MEMBRANE; TEICHOIC ACIDS; TOLL-LIKE RECEPTOR 2; TRANSCRIPTION FACTOR AP-1;

EID: 77950083597     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2010.01.025     Document Type: Article

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