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Volumn 35, Issue 2, 2011, Pages 226-235

Spontaneous caloric restriction associated with increased leptin levels in obesity-resistant αmUPA mice

Author keywords

MUPA; calorie restriction; leptin; satiety; SIRT1

Indexed keywords

ADENOSINE PHOSPHATE; GHRELIN; GLUCOSE; LEPTIN; LIPID; MESSENGER RNA; NEUROPEPTIDE; NUCLEAR FACTOR Y; OREXIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN MCH; PROTEIN POMC; UNCLASSIFIED DRUG;

EID: 79951675537     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2010.125     Document Type: Article
Times cited : (19)

References (60)
  • 1
    • 17844401704 scopus 로고    scopus 로고
    • Anatomy and regulation of the central melanocortin system
    • DOI 10.1038/nn1455
    • Cone RD. Anatomy and regulation of the central melanocortin system. Nat Neurosci 2005; 8: 571-578. (Pubitemid 40594196)
    • (2005) Nature Neuroscience , vol.8 , Issue.5 , pp. 571-578
    • Cone, R.D.1
  • 3
    • 0036851553 scopus 로고    scopus 로고
    • Orexin-mediated feeding behavior involves both leptin-sensitive and -insensitive pathways
    • DOI 10.1016/S0031-9384(02)00843-0, PII S0031938402008430
    • Zhu Y, Yamanaka A, Kunii K, Tsujino N, Goto K, Sakurai T. Orexin-mediated feeding behavior involves both leptin-sensitive and-insensitive pathways. Physiol Behav 2002; 77: 251-257. (Pubitemid 35375255)
    • (2002) Physiology and Behavior , vol.77 , Issue.2-3 , pp. 251-257
    • Zhu, Y.1    Yamanaka, A.2    Kunii, K.3    Tsujino, N.4    Goto, K.5    Sakurai, T.6
  • 4
    • 20844451123 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
    • DOI 10.1016/j.cmet.2004.12.003, PII S1550413104000099
    • Kahn BB, Alquier T, Carling D, Hardie DG. AMP-activated protein kinase: ancient energy gauge provides clues to modern under-standing of metabolism. Cell Metab 2005; 1: 15-25. (Pubitemid 43960587)
    • (2005) Cell Metabolism , vol.1 , Issue.1 , pp. 15-25
    • Kahn, B.B.1    Alquier, T.2    Carling, D.3    Hardie, D.G.4
  • 9
    • 69849107217 scopus 로고    scopus 로고
    • Caloric restriction, SIRT1 and longevity
    • Canto C, Auwerx J. Caloric restriction, SIRT1 and longevity. Trends Endocrinol Metab 2009; 20: 325-331.
    • (2009) Trends Endocrinol Metab , vol.20 , pp. 325-331
    • Canto, C.1    Auwerx, J.2
  • 11
    • 64549127790 scopus 로고    scopus 로고
    • PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure
    • Canto C, Auwerx J. PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure. Curr Opin Lipidol 2009; 20: 98-105.
    • (2009) Curr Opin Lipidol , vol.20 , pp. 98-105
    • Canto, C.1    Auwerx, J.2
  • 15
    • 0032549811 scopus 로고    scopus 로고
    • A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis
    • DOI 10.1016/S0092-8674(00)81410-5
    • Puigserver P, Wu Z, Park CW, Graves R, Wright M, Spiegelman BM. A cold-inducible coactivator of nuclear receptors linked to adaptive thermogenesis. Cell 1998; 92: 829-839. (Pubitemid 28155321)
    • (1998) Cell , vol.92 , Issue.6 , pp. 829-839
    • Puigserver, P.1    Wu, Z.2    Park, C.W.3    Graves, R.4    Wright, M.5    Spiegelman, B.M.6
  • 16
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • DOI 10.1146/annurev.med.53.082901.104018
    • Berger J, Moller DE. The mechanisms of action of PPARs. Annu Rev Med 2002; 53: 409-435. (Pubitemid 34177889)
    • (2002) Annual Review of Medicine , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 18
    • 0025297143 scopus 로고
    • Human and murine urokinase cDNAs linked to the murine αA-crystallin promoter exhibites lens and non-lens expression in transgenic mice
    • DOI 10.1111/j.1432-1033.1990.tb15541.x
    • Miskin R, Axelrod JH, Griep AE, Lee E, Belin D, Vassalli JD et al. Human and murine urokinase cDNAs linked to the murine alpha A-crystallin promoter exhibit lens and non-lens expression in transgenic mice. Eur J Biochem 1990; 190: 31-38. (Pubitemid 20183960)
    • (1990) European Journal of Biochemistry , vol.190 , Issue.1 , pp. 31-38
    • Miskin, R.1    Axelrod, J.H.2    Griep, A.E.3    Lee, E.4    Belin, D.5    Vassalli, J.-D.6    Westphal, H.7
  • 19
    • 3242699717 scopus 로고    scopus 로고
    • UPA and uPAR in fibrinolysis, immunity and pathology
    • DOI 10.1016/j.it.2004.06.004, PII S1471490604001851
    • Mondino A, Blasi F. uPA and uPAR in fibrinolysis, immunity and pathology. Trends Immunol 2004; 25: 450-455. (Pubitemid 38951087)
    • (2004) Trends in Immunology , vol.25 , Issue.8 , pp. 450-455
    • Mondino, A.1    Blasi, F.2
  • 20
    • 0020986098 scopus 로고
    • Plasminogen activator in the developing rat cerebellum: Biosynthesis and localization in granular neurons
    • DOI 10.1016/0165-3806(83)90212-2
    • Soreq H, Miskin R. Plasminogen activator in the developing rat cerebellum: biosynthesis and localization in granular neurons. Brain Res 1983; 313: 149-158. (Pubitemid 14177879)
    • (1983) Developmental Brain Research , vol.11 , Issue.2 , pp. 149-158
    • Soreq, H.1    Miskin, R.2
  • 21
    • 0026453524 scopus 로고
    • The expression of tissue and urokinase-type plasminogen activators in neural development suggests different modes of proteolytic involvement in neuronal growth
    • Sumi Y, Dent MA, Owen DE, Seeley PJ, Morris RJ. The expression of tissue and urokinase-type plasminogen activators in neural development suggests different modes of proteolytic involvement in neuronal growth. Development 1992; 116: 625-637.
    • (1992) Development , vol.116 , pp. 625-637
    • Sumi, Y.1    Dent, M.A.2    Owen, D.E.3    Seeley, P.J.4    Morris, R.J.5
  • 22
    • 0030945560 scopus 로고    scopus 로고
    • MRNAs encoding urokinase-type plasminogen activator and plasminogen activator inhibitor-1 are elevated in the mouse brain following kainate-mediated excitation
    • DOI 10.1016/S0169-328X(97)00040-5, PII S0169328X97000405
    • Masos T, Miskin R. mRNAs encoding urokinase-type plaminogen activator and plasminogen activator inhibitor-1 are elevated in the mouse brain following kainate-mediated excitation. Brain Res Mol Brain Res 1997; 47: 157-169. (Pubitemid 27268271)
    • (1997) Molecular Brain Research , vol.47 , Issue.1-2 , pp. 157-169
    • Masos, T.1    Miskin, R.2
  • 23
    • 10944240588 scopus 로고    scopus 로고
    • In vivo gene delivery of urokinase-type plasminogen activator with regulatable lentivirus induces behavioural changes in chronic cocaine administration
    • DOI 10.1111/j.1460-9568.2004.03771.x
    • Bahi A, Boyer F, Gumy C, Kafri T, Dreyer JL. In vivo gene delivery of urokinase-type plasminogen activator with regulatable lentivirus induces behavioural changes in chronic cocaine administration. Eur J Neurosci 2004; 20: 3473-3488. (Pubitemid 40013557)
    • (2004) European Journal of Neuroscience , vol.20 , Issue.12 , pp. 3473-3488
    • Bahi, A.1    Boyer, F.2    Gumy, C.3    Kafri, T.4    Dreyer, J.-L.5
  • 24
    • 40349093347 scopus 로고    scopus 로고
    • Overexpression of plasminogen activators in the nucleus accumbens enhances cocaine-, amphetamine- and morphine-induced reward and behavioral sensitization
    • DOI 10.1111/j.1601-183X.2007.00346.x
    • Bahi A, Dreyer JL. Overexpression of plasminogen activators in the nucleus accumbens enhances cocaine-, amphetamine-and morphine-induced reward and behavioral sensitization. Genes Brain Behav 2008; 7: 244-256. (Pubitemid 351342201)
    • (2008) Genes, Brain and Behavior , vol.7 , Issue.2 , pp. 244-256
    • Bahi, A.1    Dreyer, J.-L.2
  • 25
    • 33750035770 scopus 로고    scopus 로고
    • Increased expression and activity of urokinase-type plasminogen activator during epileptogenesis
    • DOI 10.1111/j.1460-9568.2006.05062.x
    • Lahtinen L, Lukasiuk K, Pitkanen A. Increased expression and activity of urokinase-type plasminogen activator during epileptogenesis. Eur J Neurosci 2006; 24: 1935-1945. (Pubitemid 44583477)
    • (2006) European Journal of Neuroscience , vol.24 , Issue.7 , pp. 1935-1945
    • Lahtinen, L.1    Lukasiuk, K.2    Pitkanen, A.3
  • 27
    • 33645663533 scopus 로고    scopus 로고
    • Urokinase-type plasminogen activator mRNA is expressed in normal developing teeth and leads to abnormal incisor enamel in alpha MUPA transgenic mice
    • Miskin R, Masos T, Shoham Z, Williams-Simons L. Urokinase-type plasminogen activator mRNA is expressed in normal developing teeth and leads to abnormal incisor enamel in alpha MUPA transgenic mice. Transgenic Res 2006; 15: 241-254.
    • (2006) Transgenic Res , vol.15 , pp. 241-254
    • Miskin, R.1    Masos, T.2    Shoham, Z.3    Williams-Simons, L.4
  • 28
    • 0031003513 scopus 로고    scopus 로고
    • Transgenic mice overexpressing urokinase-type plasminogen activator in the brain exhibit reduced food consumption, body weight and size, and increased longevity
    • Miskin R, Masos T Transgenic mice overexpressing urokinase-type plasminogen activator in the brain exhibit reduced food consumption, body weight and size, and increased longevity. J Gerontol A Biol Sci Med Sci 1997; 52: B118-B124. (Pubitemid 27123962)
    • (1997) Journals of Gerontology - Series A Biological Sciences and Medical Sciences , vol.52 , Issue.2
    • Miskin, R.1    Masos, T.2
  • 29
    • 0033233288 scopus 로고    scopus 로고
    • αMUPA mice: A transgenic model for increased life span
    • DOI 10.1016/S0197-4580(99)00093-7, PII S0197458099000937
    • Miskin R, Masos T, Yahav S, Shinder D, Globerson A. alphaMUPA mice: a transgenic model for increased life span. Neurobiol Aging 1999; 20: 555-564. (Pubitemid 30001469)
    • (1999) Neurobiology of Aging , vol.20 , Issue.5 , pp. 555-564
    • Miskina, R.1    Masos, T.2    Yahav, S.3    Shinder, D.4    Globerson, A.5
  • 31
    • 0041883767 scopus 로고    scopus 로고
    • Mitochondrion-mediated apoptosis is enhanced in long-lived αMUPA transgenic mice and calorically restricted wild-type mice
    • DOI 10.1016/S0531-5565(03)00151-7
    • Tirosh O, Aronis A, Zusman I, Kossoy G, Yahav S, Shinder D et al. Mitochondrion-mediated apoptosis is enhanced in long-lived alphaMUPA transgenic mice and calorically restricted wild-type mice. Exp Gerontol 2003; 38: 955-963. (Pubitemid 37040798)
    • (2003) Experimental Gerontology , vol.38 , Issue.9 , pp. 955-963
    • Tirosh, O.1    Aronis, A.2    Zusman, I.3    Kossoy, G.4    Yahav, S.5    Shinder, D.6    Abramovitz, R.7    Miskin, R.8
  • 32
    • 27644563992 scopus 로고    scopus 로고
    • Long-lived αMUPA transgenic mice show reduced SOD2 expression, enhanced apoptosis and reduced susceptibility to the carcinogen dimethylhydrazine
    • DOI 10.1016/j.mad.2005.07.003, PII S0047637405001739
    • Tirosh O, Pardo M, Schwartz B, Miskin R. Long-lived alphaMUPA transgenic mice show reduced SOD2 expression, enhanced apoptosis and reduced susceptibility to the carcinogen dimethyl-hydrazine. Mech Ageing Dev 2005; 126: 1262-1273. (Pubitemid 41572243)
    • (2005) Mechanisms of Ageing and Development , vol.126 , Issue.12 , pp. 1262-1273
    • Tirosh, O.1    Pardo, M.2    Schwartz, B.3    Miskin, R.4
  • 33
    • 33646472592 scopus 로고    scopus 로고
    • Defending body mass during food restriction in Acomys russatus: A desert rodent that does not store food
    • Gutman R, Choshniak I, Kronfeld-Schor N. Defending body mass during food restriction in Acomys russatus: a desert rodent that does not store food. Am J Physiol Regul Integr Comp Physiol 2006; 290: R881-R891.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Gutman, R.1    Choshniak, I.2    Kronfeld-Schor, N.3
  • 34
    • 33751170896 scopus 로고    scopus 로고
    • Long-lived alphaMUPA transgenic mice exhibit pronounced circadian rhythms
    • Froy O, Chapnik N, Miskin R. Long-lived alphaMUPA transgenic mice exhibit pronounced circadian rhythms. Am J Physiol Endocrinol Metab 2006; 291: E1017-E1024.
    • (2006) Am J Physiol Endocrinol Metab , vol.291
    • Froy, O.1    Chapnik, N.2    Miskin, R.3
  • 35
    • 58149464684 scopus 로고    scopus 로고
    • High-fat diet delays and fasting advances the circadian expression of adiponectin signaling components in mouse liver
    • Barnea M, Madar Z, Froy O. High-fat diet delays and fasting advances the circadian expression of adiponectin signaling components in mouse liver. Endocrinology 2009; 150: 161-168.
    • (2009) Endocrinology , vol.150 , pp. 161-168
    • Barnea, M.1    Madar, Z.2    Froy, O.3
  • 36
    • 25444482392 scopus 로고    scopus 로고
    • Brain regulation of food intake and appetite: Molecules and networks
    • DOI 10.1111/j.1365-2796.2005.01553.x
    • Broberger C. Brain regulation of food intake and appetite: molecules and networks. JIntern Med 2005; 258: 301-327. (Pubitemid 41368681)
    • (2005) Journal of Internal Medicine , vol.258 , Issue.4 , pp. 301-327
    • Broberger, C.1
  • 38
    • 13944253348 scopus 로고    scopus 로고
    • Calorie restriction - The SIR2 connection
    • Guarente L, Picard F. Calorie restriction-the SIR2 connection. Cell 2005; 120: 473-482.
    • (2005) Cell , vol.120 , pp. 473-482
    • Guarente, L.1    Picard, F.2
  • 39
    • 33745204479 scopus 로고    scopus 로고
    • AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues
    • DOI 10.1113/jphysiol.2006.113217
    • Xue B, Kahn BB. AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. J Physiol 2006; 574: 73-83. (Pubitemid 43905798)
    • (2006) Journal of Physiology , vol.574 , Issue.1 , pp. 73-83
    • Xue, B.1    Kahn, B.B.2
  • 43
    • 50249103843 scopus 로고    scopus 로고
    • The suprachiasmatic nuclei are involved in determining circadian rhythms during restricted feeding
    • Froy O, Chapnik N, Miskin R. The suprachiasmatic nuclei are involved in determining circadian rhythms during restricted feeding. Neuroscience 2008; 155: 1152-1159.
    • (2008) Neuroscience , vol.155 , pp. 1152-1159
    • Froy, O.1    Chapnik, N.2    Miskin, R.3
  • 44
    • 14544271907 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Balancing the scales
    • DOI 10.1016/j.biochi.2004.10.017
    • Carling D. AMP-activated protein kinase: balancing the scales. Biochimie 2005; 87: 87-91. (Pubitemid 40298770)
    • (2005) Biochimie , vol.87 , Issue.1 SPEC. ISSUE , pp. 87-91
    • Carling, D.1
  • 45
    • 1042263152 scopus 로고    scopus 로고
    • Orexin: A link between energy homeostasis and adaptive behaviour
    • DOI 10.1097/00075197-200307000-00001
    • Sakurai T. Orexin: a link between energy homeostasis and adaptive behaviour. Curr Opin Clin Nutr Metab Care 2003; 6: 353-360. (Pubitemid 40684584)
    • (2003) Current Opinion in Clinical Nutrition and Metabolic Care , vol.6 , Issue.4 , pp. 353-360
    • Sakurai, T.1
  • 46
    • 17044427583 scopus 로고    scopus 로고
    • Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: Regulation by cholecystokinin and opioids
    • Appleyard SM, Bailey TW, Doyle MW, Jin YH, Smart JL, Low MJ et al. Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids. J Neurosci 2005; 25: 3578-3585.
    • (2005) J Neurosci , vol.25 , pp. 3578-3585
    • Appleyard, S.M.1    Bailey, T.W.2    Doyle, M.W.3    Jin, Y.H.4    Smart, J.L.5    Low, M.J.6
  • 48
    • 42149139040 scopus 로고    scopus 로고
    • Lack of starvation-induced activation of AMP-activated protein kinase in the hypothalamus of the Lou/C rats resistant to obesity
    • DOI 10.1038/sj.ijo.0803759, PII 0803759
    • Taleux N, De Potter I, Deransart C, Lacraz G, Favier R, Leverve XM et al. Lack of starvation-induced activation of AMP-activated protein kinase in the hypothalamus of the Lou/C rats resistant to obesity. Int J Obes (Lond) 2008; 32: 639-647. (Pubitemid 351536008)
    • (2008) International Journal of Obesity , vol.32 , Issue.4 , pp. 639-647
    • Taleux, N.1    De Potter, I.2    Deransart, C.3    Lacraz, G.4    Favier, R.5    Leverve, X.M.6    Hue, L.7    Guigas, B.8
  • 49
    • 66149104386 scopus 로고    scopus 로고
    • The Lou/C rat: A model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue
    • Veyrat-Durebex C, Montet X, Vinciguerra M, Gjinovci A, Meda P, Foti M et al. The Lou/C rat: a model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue. Am J Physiol Endocrinol Metab 2009; 296: E1120-E1132.
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Veyrat-Durebex, C.1    Montet, X.2    Vinciguerra, M.3    Gjinovci, A.4    Meda, P.5    Foti, M.6
  • 50
    • 17144429302 scopus 로고    scopus 로고
    • Calorie restriction, SIRT1 and metabolism: Understanding longevity
    • DOI 10.1038/nrm1616
    • Bordone L, Guarente L. Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat Rev Mol Cell Biol 2005; 6: 298-305. (Pubitemid 40516896)
    • (2005) Nature Reviews Molecular Cell Biology , vol.6 , Issue.4 , pp. 298-305
    • Bordone, L.1    Guarente, L.2
  • 51
    • 22744445281 scopus 로고    scopus 로고
    • Overview of caloric restriction and ageing
    • DOI 10.1016/j.mad.2005.03.012, PII S0047637405000783
    • Masoro EJ. Overview of caloric restriction and ageing. Mech Ageing Dev2005; 126: 913-922. (Pubitemid 41033171)
    • (2005) Mechanisms of Ageing and Development , vol.126 , Issue.9 SPEC. ISSUE , pp. 913-922
    • Masoro, E.J.1
  • 55
    • 67349276169 scopus 로고    scopus 로고
    • AMPKregulates energy expenditureby modulatingNAD+ metabolism and SIRT1 activity
    • Canto C, Gerhart-Hines Z, Feige JN, Lagouge M, Noriega L, Milne JCet al. AMPKregulates energy expenditureby modulatingNAD+ metabolism and SIRT1 activity. Nature 2009; 458: 1056-1060.
    • (2009) Nature , vol.458 , pp. 1056-1060
    • Canto, C.1    Gerhart-Hines, Z.2    Feige, J.N.3    Lagouge, M.4    Noriega, L.5    Jcet Al., M.6
  • 58
    • 29344469334 scopus 로고    scopus 로고
    • Ventromedial arcuate nucleus communicates peripheral metabolic information to the suprachiasmatic nucleus
    • DOI 10.1210/en.2005-1051
    • Yi CX, van der Vliet J, Dai J, Yin G, Ru L, Buijs RM. Ventromedial arcuate nucleus communicates peripheral metabolic information to the suprachiasmatic nucleus. Endocrinology 2006; 147: 283-294. (Pubitemid 43004282)
    • (2006) Endocrinology , vol.147 , Issue.1 , pp. 283-294
    • Yi, C.-X.1    Van Der Vliet, J.2    Dai, J.3    Yin, G.4    Ru, L.5    Buijs, R.M.6
  • 59
    • 67650754345 scopus 로고    scopus 로고
    • Leptin modulates spike coding in the rat suprachiasmatic nucleus
    • Inyushkin AN, Bhumbra GS, Dyball RE. Leptin modulates spike coding in the rat suprachiasmatic nucleus. JNeuroendocrinol 2009; 21: 705-714.
    • (2009) JNeuroendocrinol , vol.21 , pp. 705-714
    • Inyushkin, A.N.1    Bhumbra, G.S.2    Dyball, R.E.3
  • 60
    • 0037461579 scopus 로고    scopus 로고
    • Leptin phase-advances the rat suprachiasmatic circadian clock in vitro
    • DOI 10.1016/S0304-3940(02)01234-X
    • Prosser RA, Bergeron HE. Leptin phase-advances the rat suprachias-matic circadian clock in vitro. Neurosci Lett 2003; 336: 139-142. (Pubitemid 36044598)
    • (2003) Neuroscience Letters , vol.336 , Issue.3 , pp. 139-142
    • Prosser, R.A.1    Bergeron, H.E.2


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