-
1
-
-
77953471201
-
Towards novel antifilarial drugs: Challenges and recent developments
-
P.K. Singh, A. Ajay, and S. Kushwaha Towards novel antifilarial drugs: challenges and recent developments Future Med Chem 2 2010 251 283
-
(2010)
Future Med Chem
, vol.2
, pp. 251-283
-
-
Singh, P.K.1
Ajay, A.2
Kushwaha, S.3
-
3
-
-
72049094540
-
Unresolved issues in anti-helmintic pharmacology for helminthiases of humans
-
T.G. Geary, K. Woo, and J.S. McCarthy Unresolved issues in anti-helmintic pharmacology for helminthiases of humans Int J Parasitol 40 2010 1 13
-
(2010)
Int J Parasitol
, vol.40
, pp. 1-13
-
-
Geary, T.G.1
Woo, K.2
McCarthy, J.S.3
-
4
-
-
47749135637
-
Ivermectin resistance in Onchocerca volvulus: Toward a genetic basis
-
S. Lustigman, and J.P. McCarter Ivermectin resistance in Onchocerca volvulus: toward a genetic basis PLoS Negl Trop Dis 1 2007 1 3
-
(2007)
PLoS Negl Trop Dis
, vol.1
, pp. 1-3
-
-
Lustigman, S.1
McCarter, J.P.2
-
5
-
-
34648836102
-
Draft genome of the filarial nematode parasite Brugia malayi
-
DOI 10.1126/science.1145406
-
E. Ghedin, S. Wang, and D. Spiro Draft genome of the filarial nematode parasite Brugia malayi Science 317 2007 1756 1760 (Pubitemid 47461841)
-
(2007)
Science
, vol.317
, Issue.5845
, pp. 1756-1760
-
-
Ghedin, E.1
Wang, S.2
Spiro, D.3
Caler, E.4
Zhao, Q.5
Crabtree, J.6
Allen, J.E.7
Delcher, A.L.8
Guiliano, D.B.9
Miranda-Saavedra, D.10
Angiuoli, S.V.11
Creasy, T.12
Amedeo, P.13
Haas, B.14
El-Sayed, N.M.15
Wortman, J.R.16
Feldblyum, T.17
Tallon, L.18
Schatz, M.19
Shumway, M.20
Koo, H.21
Salzberg, S.L.22
Schobel, S.23
Pertea, M.24
Pop, M.25
White, O.26
Barton, G.J.27
Carlow, C.K.S.28
Crawford, M.J.29
Daub, J.30
Dimmic, M.W.31
Estes, C.F.32
Foster, J.M.33
Ganatra, M.34
Gregory, W.F.35
Johnson, N.M.36
Jin, M.37
Komuniecki, R.38
Korf, I.39
Kumar, S.40
Laney, S.41
Li, B.-W.42
Li, W.43
Lindblom, T.H.44
Lustigman, S.45
Ma, D.46
Maina, C.V.47
Martin, D.M.A.48
McCarter, J.P.49
McReynolds, L.50
Mitreva, M.51
Nutman, T.B.52
Parkinson, J.53
Peregrin-Alvarez, J.M.54
Poole, C.55
Ren, Q.56
Saunders, L.57
Sluder, A.E.58
Smith, K.59
Stanke, M.60
Unnasch, T.R.61
Ware, J.62
Wei, A.D.63
Weil, G.64
Williams, D.J.65
Zhang, Y.66
Williams, S.A.67
Fraser-Liggett, C.68
Slatko, B.69
Blaxter, M.L.70
Scott, A.L.71
more..
-
7
-
-
58249093636
-
Inflammation and oxidative stress in vertebrate host-parasite systems
-
G. Sorci, and B. Faivre Inflammation and oxidative stress in vertebrate host-parasite systems Phil Trans R Soc B 364 2009 71 83
-
(2009)
Phil Trans R Soc B
, vol.364
, pp. 71-83
-
-
Sorci, G.1
Faivre, B.2
-
8
-
-
0141576694
-
Immune regulation by helminth parasites: Cellular and molecular mechanisms
-
DOI 10.1038/nri1183
-
R.M. Maizels, and M. Yazdanbakhsh Immune regulation by helminth parasites: cellular and molecular mechanisms Nat Rev Immun 3 2003 733 744 (Pubitemid 41070814)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.9
, pp. 733-744
-
-
Maizels, R.M.1
Yazdanbakhsh, M.2
-
9
-
-
0034850180
-
Immunological genomics of Brugia malayi: Filarial genes implicated in immune evasion and protective immunity
-
DOI 10.1046/j.1365-3024.2001.00397.x
-
R.M. Maizels, M.L. Blaxter, and A.L. Scott Immunological genomics of Brugia malayi: filarial genes implicated in immune evasion and protective immunity Parasit Immun 23 2001 327 344 (Pubitemid 32848285)
-
(2001)
Parasite Immunology
, vol.23
, Issue.7
, pp. 327-344
-
-
Maizels, R.M.1
Blaxter, M.L.2
Scott, A.L.3
-
10
-
-
66149110763
-
Antifilarial activity of 1,3-diarylpropen-one: Effect on glutathione-S-transferase, a phase II detoxification enzyme
-
S.K. Awasthi, N. Mishra, and S.K. Dixit Antifilarial activity of 1,3-diarylpropen-one: effect on glutathione-S-transferase, a phase II detoxification enzyme Am J Trop Med Hyg 80 2009 764 768
-
(2009)
Am J Trop Med Hyg
, vol.80
, pp. 764-768
-
-
Awasthi, S.K.1
Mishra, N.2
Dixit, S.K.3
-
11
-
-
0031841997
-
Resistance of filarial nematode parasites to oxidative stress
-
DOI 10.1016/S0020-7519(98)00107-6, PII S0020751998001076
-
M.E. Selkirk, V.P. Smith, R. Thomas, and K. Gounaris Resistance of filarial nematode parasites to oxidative stress Int J Parasitol 28 1998 1315 1332 (Pubitemid 28386943)
-
(1998)
International Journal for Parasitology
, vol.28
, Issue.9
, pp. 1315-1332
-
-
Selkirk, M.E.1
Smith, V.P.2
Thomas, G.R.3
Gounaris, K.4
-
12
-
-
25844490465
-
The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response
-
DOI 10.1101/gad.1324805
-
H. Inoue, N. Hisamoto, and J.H. An The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response Genes Dev 19 2005 2278 2283 (Pubitemid 41396903)
-
(2005)
Genes and Development
, vol.19
, Issue.19
, pp. 2278-2283
-
-
Inoue, H.1
Hisamoto, N.2
Jae, H.A.3
Oliveira, R.P.4
Nishida, E.5
Blackwell, T.K.6
Matsumoto, K.7
-
13
-
-
28044446334
-
Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3
-
DOI 10.1073/pnas.0508105102
-
J.H. An, K. Vranas, and M. Lucke Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3 Proc Natl Acad Sci USA 102 2005 16275 16280 (Pubitemid 41688904)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.45
, pp. 16275-16280
-
-
An, J.H.1
Vranas, K.2
Lucke, M.3
Inoue, H.4
Hisamoto, N.5
Matsumoto, K.6
Blackwell, T.K.7
-
14
-
-
33751382748
-
P38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans
-
DOI 10.1371/journal.pgen.0020183
-
E.R. Troemel, S.W. Chu, V. Reinke, S.S. Lee, F.M. Ausubel, and D.H. Kim p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans PLoS Genet 2 2006 1725 1739 (Pubitemid 44813572)
-
(2006)
PLoS Genetics
, vol.2
, Issue.11
, pp. 1725-1739
-
-
Troemel, E.R.1
Chu, S.W.2
Reinke, V.3
Lee, S.S.4
Ausubel, F.M.5
Kim, D.H.6
-
15
-
-
68649090472
-
P38 MAPK: Stress responses from molecular mechanisms to therapeutics
-
L. Coulthard, D. White, D. Jones, M. McDermott, and S. Burchill p38 MAPK: stress responses from molecular mechanisms to therapeutics Trends Mol Med 15 2009 369 379
-
(2009)
Trends Mol Med
, vol.15
, pp. 369-379
-
-
Coulthard, L.1
White, D.2
Jones, D.3
McDermott, M.4
Burchill, S.5
-
16
-
-
0042626242
-
SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response
-
DOI 10.1101/gad.1107803
-
J.H. An, and T.K. Blackwell SKN-1 links C. elegans mesendodermal specification to a conserved oxidative stress response Genes Dev 17 2003 1882 1893 (Pubitemid 36944565)
-
(2003)
Genes and Development
, vol.17
, Issue.15
, pp. 1882-1893
-
-
An, J.H.1
Blackwell, T.K.2
-
17
-
-
77649102440
-
Apicomplexa, trypanosome and parasitic nematode protein kinases as antiparasitic therapeutic targets
-
F. Liotta, and J.J. Siekierka Apicomplexa, trypanosome and parasitic nematode protein kinases as antiparasitic therapeutic targets Curr Opin Invest Drugs 11 2010 147 156
-
(2010)
Curr Opin Invest Drugs
, vol.11
, pp. 147-156
-
-
Liotta, F.1
Siekierka, J.J.2
-
18
-
-
0018850985
-
A simple, rapid, and sensitive DNA assay procedure
-
C. Labarca, and K. Paigen A simple, rapid, and sensitive DNA assay procedure Anal Biochem 102 1980 344 352 (Pubitemid 10115803)
-
(1980)
Analytical Biochemistry
, vol.102
, Issue.2
, pp. 344-352
-
-
Labarca, C.1
Paigen, K.2
-
19
-
-
51149102710
-
Trypan Blue exclusion test of cell viability
-
Strober W. Trypan Blue exclusion test of cell viability. Curr Proto Immun Appendix 2001:3B.
-
(2001)
Curr Proto Immun Appendix
-
-
Strober, W.1
-
20
-
-
33645422228
-
Production of active recombinant mitogen-activated protein kinases through transient transfection of 293T cells
-
Q. Zaho, P. Chen, M.E. Manson, and Y. Liu Production of active recombinant mitogen-activated protein kinases through transient transfection of 293T cells Prot Exp Purif 46 2006 468 474
-
(2006)
Prot Exp Purif
, vol.46
, pp. 468-474
-
-
Zaho, Q.1
Chen, P.2
Manson, M.E.3
Liu, Y.4
-
21
-
-
0032745423
-
RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase
-
S.A. Wadsworth, D.E. Cavender, and S.A. Beers RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase J Pharmacol Exp Ther 291 1999 680 687 (Pubitemid 29503541)
-
(1999)
Journal of Pharmacology and Experimental Therapeutics
, vol.291
, Issue.2
, pp. 680-687
-
-
Wadsworth, S.A.1
Cavender, D.E.2
Beers, S.A.3
Lalan, P.4
Schafer, P.H.5
Malloy, E.A.6
Wu, W.7
Fahmy, B.8
Olini, G.C.9
Davis, J.E.10
Pellegrino-Gensey, J.L.11
Wachter, M.P.12
Siekierka, J.J.13
-
22
-
-
36048945922
-
ImageJ for microscopy
-
T.J. Collins ImageJ for microscopy Biotechniques 43 2007 25 30
-
(2007)
Biotechniques
, vol.43
, pp. 25-30
-
-
Collins, T.J.1
-
24
-
-
0032212557
-
Purification and activation of recombinant p38 isoforms α, β, γ and δ
-
DOI 10.1006/prep.1998.0947
-
G.A. Keesler, J. Bray, and J. Hunt Purification and activation of recombinant p38 isoforms α, β, γ, and δ Prot Exp Purif 14 1998 221 228 (Pubitemid 28504167)
-
(1998)
Protein Expression and Purification
, vol.14
, Issue.2
, pp. 221-228
-
-
Keesler, G.A.1
Bray, J.2
Hunt, J.3
Johnson, D.A.4
Gleason, T.5
Yao, Z.6
Wang, S.-W.7
Parker, C.8
Yamane, H.9
Cole, C.10
Lichenstein, H.S.11
-
25
-
-
18344395134
-
Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site
-
DOI 10.1038/nsb770
-
C. Pargellis, L. Tong, and L. Churchill Inhibition of p38 MAP kinase by utilizing a novel allosteric binding site Nat Struct Biol 9 2002 268 272 (Pubitemid 34289898)
-
(2002)
Nature Structural Biology
, vol.9
, Issue.4
, pp. 268-272
-
-
Pargellis, C.1
Tong, L.2
Churchill, L.3
Cirillo, P.F.4
Gilmore, T.5
Graham, A.G.6
Grob, P.M.7
Hickey, E.R.8
Moss, N.9
Pav, S.10
Regan, J.11
-
26
-
-
21244476768
-
BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo
-
DOI 10.1074/jbc.M414221200
-
Y. Kuma, G. Sabio, J. Bain, N. Shpiro, R. Marquez, and A. Cuenda BIRB796 inhibits all p38 MAPK isoforms in vitro and in vivo J Biol Chem 280 2005 19472 19479 (Pubitemid 41379467)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.20
, pp. 19472-19479
-
-
Kuma, Y.1
Sabio, G.2
Bain, J.3
Shpiro, N.4
Marquez, R.5
Cuenda, A.6
-
27
-
-
0028988138
-
SB 203580 is a specific inhibitor of a MAP kinase homolog which is stimulated by cellular stresses and interleukin 1
-
A. Cuenda, J. Rouse, and Y.N. Doza SB 203580 is a specific inhibitor of a MAP kinase homolog which is stimulated by cellular stresses and interleukin 1 FEBS Lett 364 1995 229 233
-
(1995)
FEBS Lett
, vol.364
, pp. 229-233
-
-
Cuenda, A.1
Rouse, J.2
Doza, Y.N.3
-
28
-
-
0024433194
-
The further application of MTT-formazan colorimetry to studies on filarial worm viability
-
J.C.W. Comley, S. Townson, M.J. Rees, and A. Dobinson The further application of MTT-formazan colorimetry to studies on filarial worm viability Trop Med Parasitol 40 1989 311 316 (Pubitemid 19251003)
-
(1989)
Tropical Medicine and Parasitology
, vol.40
, Issue.3
, pp. 311-316
-
-
Comley, J.C.W.1
Townson, S.2
Rees, M.J.3
Dobinson, A.4
-
30
-
-
70349251884
-
Enzymatic antioxidant systems in helminth parasites
-
L. Chiumiento, and F. Bruschi Enzymatic antioxidant systems in helminth parasites Parasitol Res 105 2009 593 603
-
(2009)
Parasitol Res
, vol.105
, pp. 593-603
-
-
Chiumiento, L.1
Bruschi, F.2
-
31
-
-
70350302349
-
NADPH oxidases in innate immunity
-
G.M. Bokoch NADPH oxidases in innate immunity J Innate Imm 1 2009 507 508
-
(2009)
J Innate Imm
, vol.1
, pp. 507-508
-
-
Bokoch, G.M.1
-
32
-
-
35348981196
-
Activation of SKN-1 by novel kinases in Caenorhabditis elegans
-
DOI 10.1016/j.freeradbiomed.2007.08.025, PII S089158490700562X
-
A. Kell, N. Ventura, N. Kahn, and T.E. Johnson Activation of SKN-1 by novel kinases in Caenorhabditis elegans Free Radic Biol Med 43 2007 1560 1566 (Pubitemid 47615400)
-
(2007)
Free Radical Biology and Medicine
, vol.43
, Issue.11
, pp. 1560-1566
-
-
Kell, A.1
Ventura, N.2
Kahn, N.3
Johnson, T.E.4
-
33
-
-
33749988493
-
Endomesoderm specification in Caenorhabditis elegans and other nematodes
-
DOI 10.1002/bies.20480
-
M.F. Maduro Endomesoderm specification in Caenorhabditis elegans and other nematodes BioEssays 28 2006 1010 1022 (Pubitemid 44570450)
-
(2006)
BioEssays
, vol.28
, Issue.10
, pp. 1010-1022
-
-
Maduro, M.F.1
-
34
-
-
34249708427
-
RNA interference in parasitic helminths: Current situation, potential pitfalls and future prospects
-
DOI 10.1017/S0031182006002071
-
P. Geldhof, A. Visser, and D. Clark RNA interference in parasitic helminths: current situation, potential pitfalls and future prospects Parasitology 134 2007 609 619 (Pubitemid 46841605)
-
(2007)
Parasitology
, vol.134
, Issue.5
, pp. 609-619
-
-
Geldhof, P.1
Visser, A.2
Clark, D.3
Saunders, G.4
Britton, C.5
Gilleard, J.6
Berriman, M.7
Knox, D.8
-
35
-
-
33847310222
-
RNA interference in parasitic nematodes of animals: A reality check?
-
D.P. Knox, P. Geldhof, A. Visser, and C. Britton RNA interference in parasitic nematodes of animals: a reality check? Trends Parasitol 23 2007 105 107
-
(2007)
Trends Parasitol
, vol.23
, pp. 105-107
-
-
Knox, D.P.1
Geldhof, P.2
Visser, A.3
Britton, C.4
-
36
-
-
71849093559
-
Structural modeling and simulation studies of Brugia malayi glutathione-S-transferase with compounds exhibiting antifilarial activity: Implications in drug targeting and designing
-
M. Yadav, A. Singh, S. Rathaur, and E. Liebau Structural modeling and simulation studies of Brugia malayi glutathione-S-transferase with compounds exhibiting antifilarial activity: implications in drug targeting and designing J Mol Graph Model 28 2010 435 445
-
(2010)
J Mol Graph Model
, vol.28
, pp. 435-445
-
-
Yadav, M.1
Singh, A.2
Rathaur, S.3
Liebau, E.4
-
37
-
-
0033735542
-
Identification and localization of glutathione S-transferase as a potential target enzyme in Brugia species
-
U.R. Rao, G. Salinas, K. Mehta, and T.R. Klei Identification and localization of glutathione S-transferase as a potential target enzyme in Brugia species Parasitol Res 86 2000 908 915
-
(2000)
Parasitol Res
, vol.86
, pp. 908-915
-
-
Rao, U.R.1
Salinas, G.2
Mehta, K.3
Klei, T.R.4
|